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المؤلفون: Richard C. Turkington, Kieran Foley, Kevin M. Bradley, Richard D. Kennedy, David Campbell, Martin Eatock, Eoin Napier, Anita Lavery
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Foley, K G, Lavery, A, Napier, E, Campbell, D, Eatock, M M, Kennedy, R D, Bradley, K M & Turkington, R C 2021, ' A DNA-damage immune response assay combined with PET biomarkers predicts response to neo-adjuvant chemotherapy and survival in oesophageal adenocarcinoma ', Scientific Reports, vol. 11, no. 1, 13061 . https://doi.org/10.1038/s41598-021-92545-w
Scientific Reportsمصطلحات موضوعية: Male, Oncology, Esophageal Neoplasms, medicine.medical_treatment, Oesophageal adenocarcinoma, Logistic regression, 0302 clinical medicine, Medicine, 030212 general & internal medicine, Esophageal Neoplasms/diagnostic imaging, Neoplasm Recurrence, Local/pathology, Cancer, Aged, 80 and over, Immunoassay, Multidisciplinary, Hazard ratio, Gastroenterology, Middle Aged, Neoadjuvant Therapy, Adenocarcinoma/diagnostic imaging, 030220 oncology & carcinogenesis, Female, Adult, medicine.medical_specialty, Science, Adenocarcinoma, Sensitivity and Specificity, Article, Disease-Free Survival, 03 medical and health sciences, Immune system, Predictive Value of Tests, Internal medicine, Biomarkers, Tumor, Humans, In patient, Neo adjuvant chemotherapy, Aged, Proportional Hazards Models, Chemotherapy, business.industry, Proportional hazards model, DNA Damage/immunology, Survival Analysis, Biomarkers, Tumor/metabolism, Positron-Emission Tomography, Multivariate Analysis, Neoplasm Recurrence, Local, business, Biomarkers, DNA Damage
وصف الملف: application/pdf
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المؤلفون: El Mashed, Shereen, O'Donovan, Tracey R., Kay, Elaine, O'Grady, Anthony, McManus, Damian, Turkington, Richard C., McKenna, Sharon L.
المصدر: El Mashed, S, O'Donovan, T R, Kay, E, O'Grady, A, McManus, D, Turkington, R C & McKenna, S L 2022, ' Apoptosis and autophagy markers predict survival in neoadjuvant treated oesophageal adenocarcinoma patients ', BMC Cancer, vol. 22, 908 . https://doi.org/10.1186/s12885-022-09981-8
مصطلحات موضوعية: autophagy, Cancer Research, Esophageal Neoplasms, Caspase 3, Apoptosis, Adenocarcinoma, Prognosis, Neoadjuvant Therapy, predictive biomarkers, Caspase-3, SDG 3 - Good Health and Well-being, Oncology, Biomarkers, Tumor - metabolism, Autophagy, Biomarkers, Tumor, Genetics, oesophageal adenocarcinoma, Humans, LC3B, Adenocarcinoma - pathology, Retrospective Studies
وصف الملف: application/pdf
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المؤلفون: Swartz, Justin E., Smits, Hilde J.G., Philippens, Marielle E.P., de Bree, Remco, H.A.M. Kaanders, Johannes, Willems, Stefan M.
المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS)
المصدر: Oral Oncology, 128
Oral Oncology, 128. ELSEVIER SCIENCE BV
Oral Oncology, 128:105862. ELSEVIER SCIENCE BVمصطلحات موضوعية: EXPRESSION, Cancer Research, CLINICAL-RELEVANCE, ADVANCED HEAD, Image Processing, Biomarkers/metabolism, alpha Subunit/metabolism, OXYGEN, TUMOR HYPOXIA, Laryngeal Neoplasms/pathology, CHEMORADIATION, Computer-Assisted, Image Processing, Computer-Assisted, Pathology, Biomarkers, Tumor, Tumor/metabolism, Humans, Hypoxia, Laryngeal Neoplasms, NECK, Hypoxia-Inducible Factor 1, alpha Subunit/metabolism, Microscopy, Staining and Labeling, Squamous Cell Carcinoma of Head and Neck, Reproducibility of Results, PREDICTIVE-VALUE, Hypoxia-Inducible Factor 1, alpha Subunit, Prognosis, Cell Hypoxia, Oncology, Head and Neck Neoplasms, Nitroimidazoles, Biomarkers, Tumor/metabolism, INDUCIBLE FACTORS, Hypoxia-Inducible Factor 1, Oral Surgery, Biomarkers, RADIOTHERAPY, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
وصف الملف: application/pdf
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4رسالة جامعية
المؤلفون: Franklin, Oskar
المساهمون: Umeå universitet. Institutionen för kirurgisk och perioperativ vetenskap
مصطلحات موضوعية: Pancreatic cancer, Stroma, Basement membrane, Tumour markers, Type IV collagen, Endostatin, Osteopontin, Tenascin c, Hyaluronan, CD44, Micro-RNA, Adenocarcinoma -- metabolism, Adenocarcinoma -- pathology, Biomarkers, tumor -- metabolism, Carcinoma, pancreatic ductal -- metabolism, Carcinoma, pancreatic ductal -- pathology, Apoptosis, Autocrine communication, Cell movement, Collagen type IV -- metabolism
Degree: Diss. (sammanfattning) Umeå : Umeå universitet, 2016
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المؤلفون: Tereza Losmanová, Ralph A. Schmid, Mario P. Tschan, Philipp Zens, Amina Scherz, Sabina Berezowska
المصدر: Cells
Cells, vol. 10, no. 10, pp. 2731
Cells, Vol 10, Iss 2731, p 2731 (2021)
Losmanová, Tereza; Zens, Philipp; Scherz, Amina; Schmid, Ralph; Tschan, Mario P.; Berezowska, Sabina Anna (2021). Chaperone-Mediated Autophagy Markers LAMP2A and HSPA8 in Advanced Non-Small Cell Lung Cancer after Neoadjuvant Therapy. Cells, 10(10) MDPI 10.3390/cells10102731 <http://dx.doi.org/10.3390/cells10102731>
Volume 10
Issue 10مصطلحات موضوعية: Oncology, Male, medicine.medical_specialty, Lung Neoplasms, HSC70, QH301-705.5, medicine.medical_treatment, 610 Medicine & health, Chaperone-Mediated Autophagy, Article, Disease-Free Survival, LAMP2A, Chaperone-mediated autophagy, Internal medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Lysosomal-Associated Membrane Protein 2, medicine, Biomarkers, Tumor, HSPA8, Humans, Biology (General), Lung cancer, Survival analysis, Neoadjuvant therapy, non-small cell lung cancer, chaperone-mediated autophagy (CMA), Aged, business.industry, Autophagy, HSC70 Heat-Shock Proteins, General Medicine, Biomarkers, Tumor/metabolism, Carcinoma, Non-Small-Cell Lung/metabolism, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/therapy, Female, HSC70 Heat-Shock Proteins/metabolism, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Lung Neoplasms/therapy, Lysosomal-Associated Membrane Protein 2/metabolism, Middle Aged, Multivariate Analysis, Neoadjuvant Therapy, lung cancer, neoadjuvant therapy, medicine.disease, Clinical trial, Immunohistochemistry, 570 Life sciences, biology, business, 610 Medizin und Gesundheit, 570 Biowissenschaften, Biologie
وصف الملف: application/pdf
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6دورية أكاديمية
المؤلفون: Despierre, Evelyn, Vergote, Ignace, Anderson, Ryan, Coens, Corneel, Katsaros, Dionyssios, Hirsch, Fred R, Boeckx, Bram, Varella-Garcia, Marileila, Ferrero, Annamaria, Ray-Coquard, Isabelle, Berns, Els M J J, Casado, Antonio, Lambrechts, Diether, Jimeno, Antonio, European Organisation for Research and Treatment of Cancer-Gynaecological Cancer Group (EORTC-GCG, Groupe d’Investigateurs Nationaux pour les Etudes des Cancers de l’Ovaire (GINECO, Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (A-AGO, National Cancer Research Institute (NCRI, Australia New Zealand Gynaecological Oncology Group (ANZGOG, Mario Negri Gynecologic Oncology group (MaNGO, Goffin, Frédéric
المصدر: Targeted Oncology, 10 (4), 583 - 596 (2015-12)
مصطلحات موضوعية: Biomarkers, Tumor, Organoplatinum Compounds, Protein Kinase Inhibitors, Erlotinib Hydrochloride, Protein Kinases, EGFR protein, human, ErbB Receptors, Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Biomarkers, Tumor/genetics, Biomarkers, Tumor/metabolism, Disease Progression, Disease-Free Survival, ErbB Receptors/genetics, ErbB Receptors/metabolism, Erlotinib Hydrochloride/therapeutic use, Female, Humans, Middle Aged, Mutation, Organoplatinum Compounds/administration & dosage, Ovarian Neoplasms/drug therapy, Ovarian Neoplasms/enzymology, Ovarian Neoplasms/genetics, Protein Kinase Inhibitors/therapeutic use, Protein Kinases/genetics, Protein Kinases/metabolism, Antineoplastic Combined Chemotherapy Protocols, Ovarian Neoplasms, Receptor, Epidermal Growth Factor, Oncology, Cancer Research, Pharmacology (medical), Human health sciences, Sciences de la santé humaine, Oncologie
Relation: http://link.springer.com/content/pdf/10.1007/s11523-015-0369-6.pdf; urn:issn:1776-2596; urn:issn:1776-260X
URL الوصول: https://orbi.uliege.be/handle/2268/309161
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المؤلفون: Ella Reed, Clemens Gutmann, Bhawana Singh, Torsten Tonn, Sean A. Burnap, Salvatore Napoli, Ajay M. Shah, Jonathan D. Edgeworth, Manu Shankar-Hari, Konstantinos Theofilatos, Kaloyan Takov, Lukas E Schmidt, Kevin O'Gallagher, Katie J. Doores, Mauro Giacca, Rafael Fernandez-Leiro, Konstantina Dimitrakopoulou, Barnaby Sanderson, Mansoor Saqi, Mark J. W. McPhail, Adrian Hayday, Hashim Ali, Salma F Mujib, Georg Auzinger, Matthew Fish, Romy Kronstein-Wiedemann, Manuel Mayr, Francesca Trovato, Marieke Rienks, Stefan R. Bornstein, Christian Cassel, Umar Niazi, Adam Nabeebaccus, Silke Braun, Blair Merrick, Maria Hasman, Xiaoke Yin
المساهمون: Gutmann, Clemens [0000-0003-0675-8632], Takov, Kaloyan [0000-0002-8642-6306], Burnap, Sean A [0000-0002-3408-8608], Singh, Bhawana [0000-0002-5834-8320], Theofilatos, Konstantinos [0000-0001-6799-0553], Fish, Matthew [0000-0001-6462-3889], Schmidt, Lukas E [0000-0001-7565-1455], Rienks, Marieke [0000-0002-0590-9518], Yin, Xiaoke [0000-0002-5172-0935], Sanderson, Barnaby [0000-0002-9621-143X], Merrick, Blair [0000-0002-6061-6064], Niazi, Umar [0000-0001-7176-8883], Fernández-Leiro, Rafael [0000-0002-7941-0357], Braun, Silke [0000-0002-2558-1521], Doores, Katie J [0000-0002-5507-1725], Bornstein, Stefan R [0000-0002-5211-2536], Tonn, Torsten [0000-0001-9580-2193], Hayday, Adrian C [0000-0002-9495-5793], Giacca, Mauro [0000-0003-2927-7225], Shankar-Hari, Manu [0000-0002-5338-2538], Mayr, Manuel [0000-0002-0597-829X], Apollo - University of Cambridge Repository
المصدر: Gutmann, C, Takov, K, Burnap, S A, Singh, B, Ali, H, Theofilatos, K, Reed, E, Hasman, M, Nabeebaccus, A, Fish, M, McPhail, M J, O'Gallagher, K, Schmidt, L E, Cassel, C, Rienks, M, Yin, X, Auzinger, G, Napoli, S, Mujib, S F, Trovato, F, Sanderson, B, Merrick, B, Niazi, U, Saqi, M, Dimitrakopoulou, K, Fernández-Leiro, R, Braun, S, Kronstein-Wiedemann, R, Doores, K J, Edgeworth, J D, Shah, A M, Bornstein, S R, Tonn, T, Hayday, A C, Giacca, M, Shankar-Hari, M & Mayr, M 2021, ' SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care ', Nature Communications, vol. 12, no. 1, pp. 3406 . https://doi.org/10.1038/s41467-021-23494-1
Nature Communications
Gutmann, C, Takov, K, Burnap, S A, Singh, B, Ali, H, Theofilatos, K, Reed, E, Hasman, M, Nabeebaccus, A, Fish, M, McPhail, M J, O'Gallagher, K, Schmidt, L E, Cassel, C, Rienks, M, Yin, X, Auzinger, G, Napoli, S, Mujib, S F, Trovato, F, Sanderson, B, Merrick, B, Niazi, U, Saqi, M, Dimitrakopoulou, K, Fernández-Leiro, R, Braun, S, Kronstein-Wiedemann, R, Doores, K J, Edgeworth, J D, Shah, A M, Bornstein, S R, Tonn, T, Hayday, A C, Giacca, M, Shankar-Hari, M & Mayr, M 2021, ' SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care ', Nature Communications, vol. 12, no. 1, 3406 . https://doi.org/10.1038/s41467-021-23494-1
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)مصطلحات موضوعية: 0301 basic medicine, Proteomics, Male, General Physics and Astronomy, Kaplan-Meier Estimate, law.invention, Prognostic markers, 0302 clinical medicine, law, Medicine, Mannan-binding lectin, Serum Amyloid P-Component/metabolism, Multidisciplinary, biology, COVID-19/metabolism, Antigens, Neoplasm/metabolism, Hazard ratio, PTX3, Viral Load, Middle Aged, Intensive care unit, Antibodies, Neutralizing/immunology, Serum Amyloid P-Component, C-Reactive Protein, 030220 oncology & carcinogenesis, Spike Glycoprotein, Coronavirus, RNA, Viral, Female, Antibody, Proteomics/methods, Adult, medicine.medical_specialty, Critical Care, Science, General Biochemistry, Genetics and Molecular Biology, Article, Sepsis, 03 medical and health sciences, Antigens, Neoplasm, SARS-CoV-2/genetics, Internal medicine, Intensive care, Biomarkers, Tumor, Animals, Humans, RNA, Viral/blood, Mass spectrometry, business.industry, SARS-CoV-2, C-Reactive Protein/metabolism, Viral Load/immunology, Critical Care/statistics & numerical data, COVID-19, General Chemistry, medicine.disease, Antibodies, Neutralizing, Complement system, 030104 developmental biology, HEK293 Cells, Biomarkers, Tumor/metabolism, biology.protein, Spike Glycoprotein, Coronavirus/immunology, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b54981bd87b0451c4c66e6cc9dea4d
https://www.pure.ed.ac.uk/ws/files/263687109/s41467_021_23494_1.pdf -
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المؤلفون: Rudi Dierckx, Laura Kist de Ruijter, Sjoerd G. Elias, Elisabeth G.E. de Vries, Marjolijn N. Lub-de Hooge, Sjoukje F. Oosting
المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS), Molecular Neuroscience and Ageing Research (MOLAR), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)
المصدر: Nature Reviews Clinical Oncology, 16(4), 241-255. Nature Publishing Group
Nature Reviews Clinical Oncology, 16, 241. Nature Publishing Groupمصطلحات موضوعية: 0301 basic medicine, Nuclear imaging, Cost-Benefit Analysis, COMPARATIVE BIODISTRIBUTION, Review, TUMOR HYPOXIA, Tumour tissue, F-18-FLUOROMISONIDAZOLE PET, 0302 clinical medicine, NECK-CANCER, METASTATIC BREAST-CANCER, Neoplasms, Tumor/metabolism, Tumor Microenvironment, ZR-89-BEVACIZUMAB PET, Medicine, Non-U.S. Gov't, IN-VIVO, Clinical Oncology, Clinical Trials as Topic, Antineoplastic Agents/economics, Research Support, Non-U.S. Gov't, Molecular Imaging/economics, Molecular Imaging, Drug development, Oncology, 030220 oncology & carcinogenesis, Biomarker (medicine), MACROPHAGE MANNOSE RECEPTOR, LOCALLY ADVANCED HEAD, Neoplasms/diagnostic imaging, Positron-Emission Tomography/economics, Antineoplastic Agents, Computational biology, Research Support, 03 medical and health sciences, POSITRON-EMISSION-TOMOGRAPHY, Journal Article, Biomarkers, Tumor, Humans, business.industry, Patient Selection, Clinical trial, 030104 developmental biology, Clinical research, Biomarkers, Tumor/metabolism, Positron-Emission Tomography, Molecular imaging, business, Biomarkers
وصف الملف: application/pdf; image/pdf
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المساهمون: Netherlands Institute for Neuroscience (NIN)
المصدر: GLIA, 67(8), 1417. John Wiley and Sons Inc.
Glia
GLIA, 33, 12941-12959. John Wiley and Sons Inc.مصطلحات موضوعية: 0301 basic medicine, Pathology, Cell, Review Article, GFAPδ, Astrocytoma/classification, Review, Central Nervous System Neoplasms, 0302 clinical medicine, GFAP delta, glioma, Tumor/metabolism, Protein Isoforms, Non-U.S. Gov't, Intermediate filament, education.field_of_study, Glial fibrillary acidic protein, biology, GFAP, Research Support, Non-U.S. Gov't, Astrocytoma, Glial Fibrillary Acidic Protein/metabolism, Neural stem cell, medicine.anatomical_structure, Neurology, GFAP variants, biomarker, Protein Isoforms/metabolism, medicine.medical_specialty, intermediate filaments, Population, macromolecular substances, Research Support, 03 medical and health sciences, Cellular and Molecular Neuroscience, Glioma, Glial Fibrillary Acidic Protein, medicine, Biomarkers, Tumor, Journal Article, Humans, Animals, Central Nervous System Neoplasms/classification, Progenitor cell, education, astrocytoma, neoplasms, medicine.disease, nervous system diseases, 030104 developmental biology, nervous system, Biomarkers, Tumor/metabolism, biology.protein, Biomarkers, 030217 neurology & neurosurgery
وصف الملف: text/plain; image/pdf; application/pdf
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المؤلفون: Rachel Deplus, Martine Duterque-Coquillaud, Anne Flourens, Edith Bonnelye, Nathalie Vanpouille, Tian V. Tian, Philippe Clézardin, Anais Fradet, Carine Delliaux, Xavier Leroy, Yvan de Launoit, Mathilde Bouchet, Arnauld Villers
المساهمون: Mécanismes de tumorigenèse et thérapies ciblées, Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches Cliniques de Montréal (IRCM), Université de Montréal (UdeM), Universitat Pompeu Fabra [Barcelona] (UPF), Physiopathologie, diagnostic et traitements des maladies osseuses / Pathophysiology, Diagnosis & Treatments of Bone Diseases (LYOS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Pôle de Biologie Pathologie Génétique [CHU Lille], This work was in part supported by the Centre national de la recherche scientifique (CNRS), Ligue nationale contre le Cancer (Comité du Pas-de-Calais), Institut national du cancer (INCa_4419), Institut Pasteur de Lille, Conseil Régional du Nord-Pas-de-Calais and Fondation pour la Recherche Médicale (FRM), Conseil Régional du Nord-Pas-de-Calais, Association pour la Recherche sur le Cancer (ARC), MINECO (Juan de la Cierva Postdoctoral Fellowship FJCI-2014-22946), ARTP (Association de Recherche sur les tumeurs de prostate)., Mécanismes de la Tumorigénèse et Thérapies Ciblées (M3T) - UMR 8161 (M3T), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Center for Genomic Regulation (CRG-UPF), CIBER de Epidemiología y Salud Pública (CIBERESP), Service d'urologie, Hôpital Huriez-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), We would like to thank M. Tardivel, A. Bongiovanni and E. Werkmeister from the BioImaging Center Lille Nord de France (BICeL) for their technical assistance, M. Canouil for his statistics advice, and M. Vernier for his bioinformatic advice and stimulating discussions. We would also like to thank the local Tumor Tissue Bank (Tumorothèque), Regional Reference Oncology Center (CRRC) (Head, Pr. M.C. Copin) in Lille, France.
المصدر: Cancer Letters
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Oncogene Proteins, Fusion, [SDV]Life Sciences [q-bio], MESH: Gene Expression Regulation, Neoplastic, Mice, SCID, urologic and male genital diseases, Fusion gene, MESH: Oncogene Proteins, Fusion/metabolism, Metastasis, Prostate cancer, 0302 clinical medicine, MESH: Animals, MESH: Mice, SCID, MESH: Osteoblasts/pathology, ComputingMilieux_MISCELLANEOUS, MESH: Prostatic Neoplasms/genetics, Endothelin-1, Bone metastasis, MESH: Prostatic Neoplasms/pathology, Tumor Burden, 3. Good health, Gene Expression Regulation, Neoplastic, Phenotype, Osteoblastic lesions, Oncology, 030220 oncology & carcinogenesis, PC-3 Cells, MESH: Bone Neoplasms/metabolism, MESH: Bone Neoplasms/secondary, MESH: PC-3 Cells, MESH: Endothelin-1/metabolism, Erg, MESH: Alkaline Phosphatase/metabolism, MESH: Cell Line, Tumor, Transplantation, Heterologous, MESH: Biomarkers, Tumor/genetics, MESH: Tumor Burden/genetics, Bone Neoplasms, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, MESH: Phenotype, TMPRSS2, MESH: Oncogene Proteins, Fusion/genetics, 03 medical and health sciences, Transcriptional regulation, Cell Line, Tumor, Biomarkers, Tumor, medicine, Animals, Humans, MESH: Transplantation, Heterologous, MESH: Biomarkers, Tumor/metabolism, Osteoblasts, MESH: Alkaline Phosphatase/genetics, MESH: Humans, MESH: Prostatic Neoplasms/metabolism, Prostatic Neoplasms, Gene rearrangement, Alkaline Phosphatase, MESH: Bone Neoplasms/genetics, MESH: Osteoblasts/metabolism, medicine.disease, MESH: Male, Collagen Type I, alpha 1 Chain, TMPRSS2:ERG, 030104 developmental biology, MESH: Endothelin-1/genetics, Cancer research, Ectopic expression
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