المؤلفون: Pedersen, MK, Eriksson, R, Reguant, R, Collin, C, Pedersen, HK, Sorup, FKH, Simon, C, Birch, AM, Larsen, M, Nielsen, AP, Belling, K, Brunak, S

المصدر: European journal of epidemiology. 38(10):1043-1052

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:153438523

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المؤلفون: Mirzaei N; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Mota BC; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Birch AM; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Davis N; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Romero-Molina C; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Katsouri L; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Palmer EOC; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Golbano A; Institute of Neurosciences, Universitat Autònoma de Barcelona, Barcelona, Spain., Riggall LJ; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Nagy I; Department of Surgery and Cancer, Imperial College London, Chelsea and Westminster Hospital, London, UK., Tyacke R; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Nutt DJ; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Sastre M; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK.

المصدر: British journal of pharmacology [Br J Pharmacol] 2021 Feb; Vol. 178 (3), pp. 654-671. Date of Electronic Publication: 2020 Dec 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/drug therapy , Imidazolines*, Amyloid beta-Peptides ; Amyloid beta-Protein Precursor/genetics ; Animals ; Cognition ; Disease Models, Animal ; Female ; Imidazoles ; Ligands ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic

المؤلفون: Katsouri L; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Birch AM; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Renziehausen AWJ; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Zach C; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Aman Y; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Steeds H; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Bonsu A; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Palmer EOC; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Mirzaei N; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Ries M; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Sastre M; Department of Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK.

المصدر: Glia [Glia] 2020 May; Vol. 68 (5), pp. 1017-1030. Date of Electronic Publication: 2019 Dec 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*pathology , Astrocytes/*pathology , Cell Proliferation/*physiology , Spatial Memory/*physiology, Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Animals ; Astrocytes/metabolism ; Disease Models, Animal ; Disease Progression ; Glial Fibrillary Acidic Protein/genetics ; Glial Fibrillary Acidic Protein/metabolism ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Memory, Short-Term/physiology ; Mice ; Mice, Transgenic

المؤلفون: Birch AM; Department of Physiology, School of Medicine & Trinity College Institute of Neuroscience & Trinity Biomedical Sciences Institute, University of Dublin, Trinity College, Dublin 2, Ireland., Kelly ÁM; Department of Physiology, School of Medicine & Trinity College Institute of Neuroscience & Trinity Biomedical Sciences Institute, University of Dublin, Trinity College, Dublin 2, Ireland. Electronic address: aikelly@tcd.ie.

المصدر: Neuropharmacology [Neuropharmacology] 2019 Feb; Vol. 145 (Pt A), pp. 59-74. Date of Electronic Publication: 2018 Apr 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

مواضيع طبية MeSH: Environment*, Cognitive Aging/*psychology , Cognitive Dysfunction/*prevention & control, Animals ; Anxiety ; Apoptosis ; Brain/blood supply ; Brain/metabolism ; Brain/pathology ; Cognition ; Cognitive Aging/physiology ; Cognitive Dysfunction/pathology ; Cognitive Dysfunction/physiopathology ; Disease Resistance ; Exploratory Behavior ; Housing, Animal ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation/prevention & control ; Male ; Neurogenesis ; Random Allocation ; Rats, Wistar ; Recognition, Psychology ; Spatial Memory

المؤلفون: Zhang N; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom., Parr CJC; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom., Birch AM; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom., Goldfinger MH; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom., Sastre M; Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 ONN, United Kingdom. Electronic address: m.sastre@imperial.ac.uk.

المصدر: Neuroscience letters [Neurosci Lett] 2018 Oct 15; Vol. 685, pp. 190-195. Date of Electronic Publication: 2018 Aug 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7972 (Electronic) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci Lett Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*genetics , Amyloid beta-Protein Precursor/*metabolism , Wnt Signaling Pathway/*physiology , beta Catenin/*metabolism, Amyloid beta-Protein Precursor/genetics ; Animals ; Cell Nucleus/metabolism ; Glycogen Synthase Kinase 3/metabolism ; Mice ; Phosphorylation ; Wnt Signaling Pathway/genetics

المؤلفون: McCoull W; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K., Bailey A; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Barton P; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K., Birch AM; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Brown AJ; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Butler HS; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Boyd S; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K., Butlin RJ; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Chappell B; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Clarkson P; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K., Collins S; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Davies RM; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Ertan A; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Hammond CD; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Holmes JL; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Lenaghan C; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Midha A; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Morentin-Gutierrez P; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K., Moore JE; IMED CVMD, AstraZeneca , Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K., Raubo P; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K., Robb G; IMED Oncology and Discovery Sciences, AstraZeneca , 310 Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2017 Apr 13; Vol. 60 (7), pp. 3187-3197. Date of Electronic Publication: 2017 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Carboxylic Acids/*chemistry , Carboxylic Acids/*pharmacology , Indazoles/*chemistry , Indazoles/*pharmacology , Receptors, G-Protein-Coupled/*agonists, Animals ; Blood Glucose/analysis ; Carboxylic Acids/pharmacokinetics ; Humans ; Indazoles/pharmacokinetics ; Mice ; Mice, Inbred C57BL ; Models, Molecular

المؤلفون: Katsouri L; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Lim YM; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Blondrath K; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Eleftheriadou I; Gene Therapy, Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Lombardero L; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Birch AM; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Mirzaei N; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom., Irvine EE; Institute for Clinical Sciences, Medical Research Council Clinical Sciences Centre, London W12 0NN, United Kingdom., Mazarakis ND; Gene Therapy, Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom; m.sastre@imperial.ac.uk n.mazarakis@imperial.ac.uk., Sastre M; Division of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom; m.sastre@imperial.ac.uk n.mazarakis@imperial.ac.uk.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Oct 25; Vol. 113 (43), pp. 12292-12297. Date of Electronic Publication: 2016 Oct 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*genetics , Amyloid Precursor Protein Secretases/*genetics , Aspartic Acid Endopeptidases/*genetics , Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*genetics , Protein Aggregation, Pathological/*genetics, Alzheimer Disease/pathology ; Alzheimer Disease/therapy ; Amyloid beta-Peptides/metabolism ; Animals ; Gene Expression Regulation/genetics ; Genetic Vectors/therapeutic use ; Humans ; Lentivirus/genetics ; Memory/physiology ; Mice, Transgenic ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/administration & dosage ; Protein Aggregation, Pathological/therapy ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology

المؤلفون: Katsouri L; Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK., Ashraf A; Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK., Birch AM; Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK., Lee KK; Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK., Mirzaei N; Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK., Sastre M; Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK. Electronic address: m.sastre@imperial.ac.uk.

المصدر: Neurobiology of aging [Neurobiol Aging] 2015 Feb; Vol. 36 (2), pp. 821-31. Date of Electronic Publication: 2014 Oct 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*drug therapy , Alzheimer Disease/*genetics , Alzheimer Disease/*metabolism , Amyloid Precursor Protein Secretases/*genetics , Amyloid beta-Peptides/*metabolism , Aspartic Acid Endopeptidases/*genetics , Fibroblast Growth Factor 2/*administration & dosage , Gene Expression/*drug effects, Alzheimer Disease/pathology ; Amyloid Precursor Protein Secretases/metabolism ; Animals ; Aspartic Acid Endopeptidases/metabolism ; Brain/metabolism ; Brain/pathology ; Cell Line ; Disease Models, Animal ; Female ; Fibroblast Growth Factor 2/metabolism ; Fibroblast Growth Factor 2/pharmacology ; Humans ; Injections, Subcutaneous ; Male ; Mice, Transgenic ; Transcription, Genetic/drug effects ; tau Proteins/metabolism