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المؤلفون: Evelien G. E. Hurkmans, Annouk C. A. M. Brand, Job A. J. Verdonschot, D. Maroeska W. M. te Loo, Marieke J. H. Coenen
المساهمون: Clinical Chemistry, MUMC+: DA KG AIOS (9), MUMC+: DA KG Lab Bedrijfsbureau (9), RS: Carim - H02 Cardiomyopathy
المصدر: BMC Cancer, 22:1326. BioMed Central Ltd.
BMC Cancer, 22(1). BioMed Central Ltdمصطلحات موضوعية: Osteosarcoma, Cancer Research, Adolescent, Bone Neoplasms/drug therapy, Bone Neoplasms, Ototoxicity, Osteosarcoma/genetics, Oncology, SDG 3 - Good Health and Well-being, Pharmacogenetics, Genetics, Humans, Cisplatin, Cisplatin/therapeutic use, Child
وصف الملف: application/pdf
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المساهمون: Poitout, Dominique G.
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المؤلفون: Thürlimann, B.
مصطلحات موضوعية: Disodium pamidronate., Bones -- Cancer -- Chemotherapy., Diphosphonates -- Therapeutic use., Diphosphonates -- pharmacology., Antineoplastic Agents -- pharmacology., Hypercalcemia -- drug therapy., Bone Neoplasms -- drug therapy., Bone Neoplasms -- secondary., Bone and Bones -- physiology.
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المؤلفون: Biver, Emmanuel
المصدر: Revue médicale suisse, Vol. 15, No 647 (2019) pp. 824-830
مصطلحات موضوعية: ddc:616, Male, Bone Density Conservation Agents/therapeutic use, Diphosphonates, Bone Neoplasms/drug therapy/secondary, Denosumab/therapeutic use, Neoplasm Recurrence, Breast Neoplasms/drug therapy, Local, Bone Density, Humans, Female, Prostatic Neoplasms/drug therapy, Androgen Antagonists/therapeutic use
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1400::47cd9184d056aa9372d407001c046813
https://archive-ouverte.unige.ch/unige:123834 -
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المؤلفون: Roberta Mazzone, Piero Picci, Katia Scotlandi, Michela Pasello, Patrizia Nanni, Giordano Nicoletti, Maria Cristina Manara, Antonello Mai, Clara Guerzoni, Camilla Cristalli, Pier Luigi Lollini, Lorena Landuzzi, Sergio Valente, Giulia Stazi, Paola B. Arimondo, Clemens Zwergel
المساهمون: Istituto Ortopedico Rizzoli [Bologna, Italy], Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Centre National de la Recherche Scientifique (CNRS), Department of Medicinal Chemistry and Technologies, Institut Pasteur, Fondation Cenci Bolognetti - Istituto Pasteur Italia, Fondazione Cenci Bolognetti, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], This work was funded by AIRC (IG 18451 to K. Scotlandi, IG 19162 to A. Mai), the Italian Ministry of Health (TRANSCAN_ project TORPEDO_ER-2015-23604059 to K. Scotlandi), Progetto Ateneo Sapienza (to A. Mai), PRIN 2016 (prot 20152TE5PK to A. Mai), and the NIH (R01GM114306 to A. Mai)., The authors thank Cristina Ghinelli for editing the manuscript., Manara, Maria Cristina, Valente, Sergio, Cristalli, Camilla, Nicoletti, Giordano, Landuzzi, Lorena, Zwergel, Clemen, Mazzone, Roberta, Stazi, Giulia, Arimondo, Paola B, Pasello, Michela, Guerzoni, Clara, Picci, Piero, Nanni, Patrizia, Lollini, Pier-Luigi, Mai, Antonello, Scotlandi, Katia
المصدر: Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩مصطلحات موضوعية: 0301 basic medicine, Male, patient-derived xenograft (PDX), MESH: Osteosarcoma/genetics, MESH: Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Cellular differentiation, DNA Methyltransferase Inhibitor, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, chemotherapy, MESH: Mice, Knockout, 0302 clinical medicine, MESH: Osteosarcoma/drug therapy, Antineoplastic Combined Chemotherapy Protocols, MESH: Aminoquinolines/administration & dosage, MESH: Animals, MESH: Quinolines/chemistry, Enzyme Inhibitors, MESH: DNA (Cytosine-5-)-Methyltransferase 1/metabolism, Mice, Knockout, DNA methylation, Chemistry, 3. Good health, Tumor Burden, MESH: Benzamides/pharmacology, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Benzamides, oncology, Aminoquinolines, Quinolines, MESH: Cisplatin/administration & dosage, MESH: Bone Neoplasms/metabolism, Osteosarcoma, MESH: Doxorubicin/administration & dosage, epigenetic, MESH: Bone Neoplasms/genetics, medicine.drug, DNA (Cytosine-5-)-Methyltransferase 1, musculoskeletal diseases, MESH: Aminoquinolines/pharmacology, MESH: Cell Line, Tumor, DNA damage, MESH: Gene Expression Regulation, Neoplastic/drug effects, MESH: Tumor Burden/genetics, MESH: Xenograft Model Antitumor Assays, Bone Neoplasms, [SDV.CAN]Life Sciences [q-bio]/Cancer, 03 medical and health sciences, Cell Line, Tumor, osteosarcoma, medicine, Animals, Humans, Doxorubicin, MESH: DNA (Cytosine-5-)-Methyltransferase 1/antagonists & inhibitors, MESH: Enzyme Inhibitors/chemistry, Cisplatin, MESH: Humans, Nucleoside inhibitor, medicine.disease, MESH: Enzyme Inhibitors/pharmacology, Xenograft Model Antitumor Assays, MESH: Male, MESH: Enzyme Inhibitors/administration & dosage, MESH: Bone Neoplasms/drug therapy, 030104 developmental biology, MESH: Osteosarcoma/metabolism, Cancer research, cancer research, MESH: DNA (Cytosine-5-)-Methyltransferase 1/genetics, MESH: Benzamides/administration & dosage, MESH: Tumor Burden/drug effects
وصف الملف: STAMPA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55d5482d55dc2ed43ad6818ec4cbf60
https://hal.archives-ouvertes.fr/hal-02383680 -
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المؤلفون: Stephen P. Jackson, Mareike Herzog, Alejandra Bruna, Luca Pellegrini, Violeta Serra, Mark J. O'Connor, Zhongwu Lai, Chloé Lescale, Jacqueline J.L. Jacobs, Fengtang Yang, Jonathan Lam, Matylda Sczaniecka-Clift, Abigail Shea, Carlos Caldas, Matthias Ostermaier, Gabriel Balmus, Julia Coates, Wenming Wei, Inge de Krijger, Yaron Galanty, Mukerrem Demir, Ludovic Deriano, Petra Beli, Domenic Pilger, Harveer Dev, Rimma Belotserkovskaya, Alistair Martin, Beiyuan Fu, Ting-Wei Will Chiang, Qian Wu
المساهمون: Dev, Harveer [0000-0003-2874-6894], Yang, Fengtang [0000-0002-3573-2354], Balmus, Gabriel [0000-0003-2872-4468], Serra, Violeta [0000-0001-6620-1065], Beli, Petra [0000-0001-9507-9820], Pellegrini, Luca [0000-0002-9300-497X], Deriano, Ludovic [0000-0002-9673-9525], Jacobs, Jacqueline JL [0000-0002-7704-4795], Jackson, Stephen P [0000-0001-9317-7937], Apollo - University of Cambridge Repository, Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge [UK] (CAM), Department of Biochemistry [Cambridge], Cambridge University Hospitals - NHS (CUH), Intégrité du génome, immunité et cancer - Genome integrity, Immunity and Cancer, Institut Pasteur [Paris] (IP), Netherlands Cancer Institute (NKI), Antoni van Leeuwenhoek Hospital, Cancer Research UK Cambridge Institute [Cambridge, Royaume-Uni] (CRUK), Institute of Molecular Biology (IMB), Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), Wellcome Trust Sanger Institute [Hinxton, UK], AstraZeneca US [Waltham, USA], AstraZeneca [Cambridge, UK], The Wellcome Trust Sanger Institute [Cambridge], Vall d'Hebron Institute of Oncology [Barcelone] (VHIO), Vall d'Hebron University Hospital [Barcelona], The SPJ lab is largely funded by a Cancer Research UK (CRUK) Program Grant, C6/A18796, and a Wellcome Trust (WT) Investigator Award, 206388/Z/17/Z. Core infrastructure funding was provided by CRUK grant C6946/A24843 and WT grant WT203144. S.P.J. receives a salary from the University of Cambridge. H.D. is funded by WT Clinical Fellowship 206721/Z/17/Z. TWC was supported by a Cambridge International Scholarship. D.P. is funded by Cancer Research UK studentship C6/A21454. The P.B. lab is supported by the Emmy Noether Program (BE 5342/1-1) from the German Research Foundation and a Marie Curie Career Integration Grant from the European Commission (630763). The L.P. lab is funded by the WT (investigator award 104641/Z/14/Z) and the Medical Research Council (project grant MR/N000161/1). The C.C. lab was supported with funding from CRUK. The J.J. lab was supported by the European Research Council grant ERC-StG 311565, The Dutch Cancer Society (KWF) grant KWF 10999, and the Netherlands Organization for Scientific Research (NWO) as part of the National Roadmap Large-scale Research Facilities of the Netherlands, Proteins@Work (project no. 184.032.201 to the Proteomics Facility of the Netherlands Cancer Institute). The L.D. lab is funded by the Institut Pasteur, the Institut National du Cancer (no. PLBIO16-181) and the European Research Council (starting grant agreement no. 310917). W.W. is part of the Pasteur–Paris University (PPU) International PhD program and this project received funding from the CNBG company, China. Q.W. is funded by the Wellcome Trust (200814/Z/16/Z ). The V.S. lab work was funded by the Instituto de Salud Carlos III (ISCIII), an initiative of the Spanish Ministry of Economy and Innovation partially supported by European Regional Development FEDER Funds (PI17-01080 to VS), the European Research Area-NET, Transcan-2 (AC15/00063), a non-commercial research agreement with AstraZeneca UK, and structural funds from the Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR, 2017 SGR 540) and the Orozco Family. V.S. received a salary and travel support to C.C.’s lab from ISCIII (CP14/00228, MV15/00041) and the FERO Foundation., The authors thank all S.P.J. laboratory members for support and advice, and Cambridge colleagues N. Lawrence for OMX super-resolution microscopy support and R. Butler for help with computational image analyses and programming. The authors also thank S. Selivanova and S. Hough for help with plasmid amplification, sample preparation and tissue culture maintenance, K. Dry for extensive editorial assistance, F. Muñoz-Martinez for assistance with CRISPR–Cas9 knockout generation, L. Radu for assistance with protein purification, C. Lord (Institute of Cancer Research, London) for SUM149PT cells, D. Durocher (University of Toronto, Canada) for U2OS LacSceIII cells, F. Alt (Harvard University, USA) for CH12F3 cells and 53bp1 knockout CH12F3 cell clones, T. Honjo (Kyoto University, Japan) for permission to use the CH12F3 cell line, and J. Serrat in the Jacobs lab for technical assistance, Institut Pasteur [Paris], Johannes Gutenberg - Universität Mainz (JGU)
المصدر: Nature Cell Biology
Nature Cell Biology, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩مصطلحات موضوعية: MESH: DNA Breaks, Double-Stranded, RAD51, Cell Cycle Proteins, Poly (ADP-Ribose) Polymerase Inhibitor, MESH: Recombinational DNA Repair, Mice, MESH: Animals, DNA Breaks, Double-Stranded, skin and connective tissue diseases, Cancer, Telomere-binding protein, Ovarian Neoplasms, MESH: Breast Neoplasms / metabolism, MESH: Telomere-Binding Proteins / metabolism, 3. Good health, Cell biology, MESH: HEK293 Cells, MESH: Proteins / genetics, MESH: Telomere-Binding Proteins / genetics, MESH: Tumor Suppressor p53-Binding Protein 1 / metabolism, MESH: Xenograft Model Antitumor Assays, Telomere-Binding Proteins, MESH: Ovarian Neoplasms / drug therapy, Bone Neoplasms, MESH: Ovarian Neoplasms / metabolism, Article, 03 medical and health sciences, MESH: Cell Cycle Proteins, MESH: Bone Neoplasms / metabolism, Humans, MESH: Osteosarcoma / metabolism, [SDV.GEN]Life Sciences [q-bio]/Genetics, MESH: Humans, MESH: Tumor Suppressor p53-Binding Protein 1 / genetics, Dose-Response Relationship, Drug, HEK 293 cells, Proteins, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, DNA, MESH: BRCA1 Protein / deficiency, 030104 developmental biology, Multiprotein Complexes, MESH: Mad2 Proteins / metabolism, MESH: Breast Neoplasms / genetics, MESH: Bone Neoplasms / drug therapy, Cisplatin, Homologous recombination, MESH: Osteosarcoma / genetics, MESH: Female, 0301 basic medicine, DNA End-Joining Repair, MESH: Proteins / metabolism, MESH: Dose-Response Relationship, Drug, chemistry.chemical_compound, MESH: Osteosarcoma / pathology, MESH: Breast Neoplasms / pathology, Homologous Recombination, Polymerase, MESH: Breast Neoplasms / drug therapy, Osteosarcoma, biology, Chemistry, BRCA1 Protein, DNA damage and repair, MESH: Poly(ADP-ribose) Polymerase Inhibitors / pharmacology, MESH: Bone Neoplasms / genetics, DNA-Binding Proteins, MESH: Bone Neoplasms / pathology, Mad2 Proteins, Female, MESH: Ovarian Neoplasms / genetics, Tumor Suppressor p53-Binding Protein 1, MESH: Cisplatin / pharmacology, MESH: Cell Line, Tumor, Lymphocytes, Null, [SDV.CAN]Life Sciences [q-bio]/Cancer, Breast Neoplasms, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, MESH: BRCA1 Protein / genetics, Poly(ADP-ribose) Polymerase Inhibitors, Cell Line, Tumor, MESH: Drug Resistance, Neoplasm* / genetics, MESH: Mad2 Proteins / genetics, MESH: Ovarian Neoplasms / pathology, Animals, MESH: Mice, MESH: Osteosarcoma / drug therapy, Oligonucleotide, Protective Devices, Recombinational DNA Repair, Cell Biology, MESH: Multiprotein Complexes, Xenograft Model Antitumor Assays, HEK293 Cells, Drug Resistance, Neoplasm, biology.protein, MESH: DNA End-Joining Repair, MESH: DNA-Binding Proteins
وصف الملف: application/pdf
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المؤلفون: Ryan, Charles J, Smith, Matthew R, Fizazi, Karim, Saad, Fred, Mulders, Peter F A, Sternberg, Cora N, Miller, Kurt, Logothetis, Christopher J, Shore, Neal D, Small, Eric J, Carles, Joan, Flaig, Thomas W, Taplin, Mary-Ellen, Higano, Celestia S, de Souza, Paul, de Bono, Johann S, Griffin, Thomas W, De Porre, Peter, Yu, Margaret K, Park, Youn C, Li, Jinhui, Kheoh, Thian, Naini, Vahid, Molina, Arturo, Rathkopf, Dana E
المساهمون: Bjartell, Anders, Creator
المصدر: The Lancet Oncology EpiHealth: Epidemiology for Health BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 16(2):60-152
مصطلحات موضوعية: Aged, Androstenes/therapeutic use, Antineoplastic Agents, Hormonal/therapeutic use, Antineoplastic Combined Chemotherapy Protocols, Bone Neoplasms/drug therapy, Disease Progression, Double-Blind Method, Follow-Up Studies, Humans, Male, Neoplasm Staging, Prednisone/therapeutic use, Prognosis, Prostatic Neoplasms, Castration-Resistant/drug therapy, Survival Rate, Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology
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المؤلفون: Mechthild Krause, Rémi Dendale, Damien C. Weber, Annika Hall, Jürgen Debus, Alessandra Bolsi, Cai Grau, Jens Heufelder, Juliette Thariat, Dirk Geismar, Andrzej Kacperek, Tomasz Kajdrowicz, Roberto Orecchia, Barbara Bachtiary, Klaus Herfarth, André N. Abrunhosa-Branquinho, V. Vondracek, Maurizio Amichetti, Kristina Nilsson
المصدر: Radiotherapy and Oncology 124(2017), 185-189
Weber, D C, Abrunhosa-Branquinho, A, Bolsi, A, Kacperek, A, Dendale, R, Geismar, D, Bachtiary, B, Hall, A, Heufelder, J, Herfarth, K, Debus, J, Amichetti, M, Krause, M, Orecchia, R, Vondracek, V, Thariat, J, Kajdrowicz, T, Nilsson, K & Grau, C 2017, ' Profile of European proton and carbon ion therapy centers assessed by the EORTC facility questionnaire ', Radiotherapy and Oncology, vol. 124, no. 2, pp. 185-189 . https://doi.org/10.1016/j.radonc.2017.07.012مصطلحات موضوعية: Medizin, Chondrosarcoma/radiotherapy, 030218 nuclear medicine & medical imaging, Eye tumors, 0302 clinical medicine, Proton Therapy/instrumentation, Surveys and Questionnaires, Proton Therapy, Medicine, 610 Medicine & health, Survey, Child, Carbon ion therapy, Brain Neoplasms, Eye Neoplasms/radiotherapy, Heavy Ion Radiotherapy/instrumentation, Hematology, CANCER, Proton therapy, Europe, EORTC, TRIALS, Oncology, Chordoma/radiotherapy, 030220 oncology & carcinogenesis, Elementary Particles, RADIOTHERAPY, medicine.medical_specialty, RADIATION ONCOLOGY GROUP, QUALITY-ASSURANCE, Brain Neoplasms/radiotherapy, Chondrosarcoma, Bone Neoplasms, Heavy Ion Radiotherapy, Pencil beam scanning, 03 medical and health sciences, Breast cancer, Chordoma, Humans, Radiology, Nuclear Medicine and imaging, Medical physics, Elementary Particles/therapeutic use, business.industry, Eye Neoplasms, Bone Neoplasms/drug therapy, medicine.disease, Carbon, Treatment modality, Carbon/chemistry, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1e115eee72813501ae93b92c24aa55
https://www.hzdr.de/publications/Publ-26981-1 -
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المؤلفون: Ciray, I., Lindman, H., Astrom, G. K., Wanders, A., Bergh, J., Ahlstrom, H. K.
المصدر: Acta Radiol. 44(5):472-84
مصطلحات موضوعية: Adult, Aged, Bone Marrow/*pathology, Bone Neoplasms/*drug therapy/*secondary, Breast Neoplasms/*pathology, Drug Therapy, Combination, Granulocyte Colony-Stimulating Factor/*therapeutic use, Humans, *Magnetic Resonance Imaging, Middle Aged, Retrospective Studies
وصف الملف: print
URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-110900
http://www.ncbi.nlm.nih.gov/pubmed/14510752