المؤلفون: Flockhart Ian, Kwon Young, Samsonova Anastasia A, Booker Matthew, Mohr Stephanie E, Perrimon Norbert

المصدر: BMC Genomics, Vol 12, Iss 1, p 50 (2011)

مصطلحات موضوعية: Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://www.biomedcentral.com/1471-2164/12/50; https://doaj.org/toc/1471-2164

URL الوصول: https://doaj.org/article/eb6a6200a90a42e395b4505498ddfd65

المؤلفون: Venkadakrishnan VB; Dana-Farber Cancer Institute., Presser AG; Dana-Farber Cancer Institute., Singh R; Weill Cornell Medicine., Booker MA; Dana-Farber Cancer Institute., Traphagen NA; Dana-Farber Cancer Institute., Weng K; Dana-Farber Cancer Institute., Voss NC; Dana-Farber Cancer Institute., Mahadevan NR; Dana-Farber Cancer Institute., Mizuno K; Dana Farber Cancer Institute., Puca L; Division of Medical Oncology, Weill Cornell Medicine., Idahor O; Dana-Farber Cancer Institute., Ku SY; Dana-Farber Cancer Institute., Bakht MK; Dana-Farber Cancer Institute., Borah AA; Broad Institute of Harvard and MIT., Herbert ZT; Dana-Farber Cancer Institute., Tolstorukov MY; Dana-Farber Cancer Institute., Barbie DA; Dana-Farber Cancer Institute., Rickman DS; Weill Cornell Medicine., Brown M; Dana-Farber Cancer Institute., Beltran H; Dana-Farber Cancer Institute.

المصدر: Research square [Res Sq] 2024 Mar 04. Date of Electronic Publication: 2024 Mar 04.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

المؤلفون: Akitsu A, Kobayashi E, Feng Y, Stephens HM, Brazin KN, Masi DJ, Kirpatrick EH, Mallis RJ, Duke-Cohan JS, Booker MA, Cinella V, Feng WW, Holliday EL, Lee JJ, Zienkiewicz KJ, Tolstorukov MY, Hwang W, Lang MJ, Reinherz EL

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 30. Date of Electronic Publication: 2023 Nov 30.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Duplaquet L; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Li Y; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, USA., Xie Y; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Olsen SN; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Patel RA; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA., Hong D; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Hatton C; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Denize T; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Walton E; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Laimon YN; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Li R; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Jiang Y; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Bronson RT; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA., Southard J; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Boston, MA, USA., Li S; Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Boston, MA, USA., Signoretti S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Qiu X; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Cejas P; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Armstrong SA; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA, USA., Long HW; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, USA., Haffner MC; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Division of Clinical Research, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Oser MG; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Matthew_Oser@dfci.harvard.edu.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, USA. Matthew_Oser@dfci.harvard.edu.

المصدر: Nature cell biology [Nat Cell Biol] 2023 Sep; Vol. 25 (9), pp. 1346-1358. Date of Electronic Publication: 2023 Aug 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Small Cell Lung Carcinoma*/genetics , Lung Neoplasms*/genetics, Humans ; Animals ; Mice ; Histone Demethylases/genetics ; Chromatin ; Epigenomics

المؤلفون: Blandin AF; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Giglio R; Dana-Farber Cancer Institute, Boston, Massachusetts., Graham MS; Memorial Sloan Kettering Cancer Center, New York, New York., Garcia G; Dana-Farber Cancer Institute, Boston, Massachusetts., Malinowski S; Dana-Farber Cancer Institute, Boston, Massachusetts., Woods JK; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Brigham and Women's Hospital, Boston, Massachusetts., Ramkissoon S; Dana-Farber Cancer Institute, Boston, Massachusetts., Ramkissoon L; Dana-Farber Cancer Institute, Boston, Massachusetts., Dubois F; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Schoolcraft K; Dana-Farber Cancer Institute, Boston, Massachusetts., Tsai J; Dana-Farber Cancer Institute, Boston, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Wang D; Dana-Farber Cancer Institute, Boston, Massachusetts., Jones R; Dana-Farber Cancer Institute, Boston, Massachusetts., Vogelzang J; Dana-Farber Cancer Institute, Boston, Massachusetts., Pelton K; Dana-Farber Cancer Institute, Boston, Massachusetts., Becker S; Dana-Farber Cancer Institute, Boston, Massachusetts., Watkinson F; Dana-Farber Cancer Institute, Boston, Massachusetts., Sinai C; Dana-Farber Cancer Institute, Boston, Massachusetts., Cohen EF; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Haemels V; Laboratory for Precision Cancer Medicine, Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Goumnerova L; TromboProtea, Inc, Weston, Massachusetts., Wright K; Dana-Farber Cancer Institute, Boston, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Kieran M; Day One Biopharmaceuticals, Brisbane, California., Fehnel K; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Reardon D; Dana-Farber Cancer Institute, Boston, Massachusetts., Tauziede-Espariat A; GHU Paris, Sainte-Anne Hospital, Paris, France., Lulla R; Hasbro Children's Hospital, Providence, Rhode Island., Carcamo B; Texas Tech University, Health Science Center, Paul L. Foster School of Medicine, El Paso, Texas.; El Paso Children's Hospital, El Paso, Texas., Chaleff S; Maine Medical Center, Portland, Maine., Charest A; Beth Israel Deaconess Medical Center, Boston, Massachusetts., De Smet F; Laboratory for Precision Cancer Medicine, Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium., Ligon AH; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Brigham and Women's Hospital, Boston, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Dubuc A; Dana-Farber Cancer Institute, Boston, Massachusetts.; Brigham and Women's Hospital, Boston, Massachusetts., Pages M; Department of Genetics, Institute Curie, Paris, France.; INSERM U830, Laboratory of Translational Research in Pediatric Oncology, SIREDO Pediatric Oncology Center, Institute Curie, Paris, France., Varlet P; GHU Paris, Sainte-Anne Hospital, Paris, France., Wen PY; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Alexander BM; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Brigham and Women's Hospital, Boston, Massachusetts., Chi S; Dana-Farber Cancer Institute, Boston, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Alexandrescu S; Dana-Farber Cancer Institute, Boston, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Kittler R; University of Texas Southwestern Medical Center, Dallas, Texas., Bachoo R; University of Texas Southwestern Medical Center, Dallas, Texas., Bandopadhayay P; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts., Beroukhim R; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Brigham and Women's Hospital, Boston, Massachusetts., Ligon KL; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Brigham and Women's Hospital, Boston, Massachusetts.; Boston Children's Cancer and Blood Disorder Center, Boston, Massachusetts.; Dana-Farber Cancer Institute, Center for Patient-Derived Models (CPDM), Boston, Massachusetts.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Jul 14; Vol. 29 (14), pp. 2651-2667.

نوع المنشور: Editorial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Glioblastoma*/drug therapy , Glioblastoma*/genetics , Glioma*/drug therapy, Mice ; Animals ; Anaplastic Lymphoma Kinase/genetics ; Retrospective Studies ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use

المؤلفون: Knelson EH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Ivanova EV; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Tarannum M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Campisi M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Lizotte PH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Ozgenc I; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Noureddine M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Meisenheimer B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Chen M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Piel B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Spicer N; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Obua B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Messier CM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Shannon E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Graduate Medical Sciences Program, Boston University School of Medicine, Boston, Massachusetts., Mahadevan NR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Tani T; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Schol PJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Lee-Hassett AM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Zlota A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Vo HV; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Ha M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Bertram AA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Han S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Thai TC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gustafson CE; Deparment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Venugopal K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Haggerty TJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Albertson TP; Deparment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Hartley AV; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Eser PO; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Li ZH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Cañadas I; Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Vivero M; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., De Rienzo A; Deparment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Richards WG; Deparment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Abu-Yousif AO; Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts., Appleman VA; Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts., Gregory RC; Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts., Parent A; Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts., Lineberry N; Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts., Smith EL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Miret JJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Romee R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Paweletz CP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts., Bueno R; Deparment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Barbie DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.

المصدر: Cancer immunology research [Cancer Immunol Res] 2022 Aug 03; Vol. 10 (8), pp. 947-961.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

مواضيع طبية MeSH: Immunotherapy, Adoptive* , Killer Cells, Natural* , Membrane Proteins*/agonists , Mesothelioma, Malignant*, Cell Line, Tumor ; Cell- and Tissue-Based Therapy ; Humans ; Receptors, Chimeric Antigen

المؤلفون: Raghavan S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Winter PS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: pswinter@mit.edu., Navia AW; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Williams HL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., DenAdel A; Center for Computational Molecular Biology, Brown University, Providence, RI 02912, USA; Division of Applied Mathematics, Brown University, Providence, RI 02912, USA., Lowder KE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Galvez-Reyes J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kalekar RL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Mulugeta N; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kapner KS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Raghavan MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Borah AA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Liu N; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Väyrynen SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Costa AD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Ng RWS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Wang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Hill EK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ragon DY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Brais LK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Jaeger AM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Spurr LF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Li YY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Cherniack AD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Cohen EF; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Wakiro I; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Rotem A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Johnson BE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., McFarland JM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Sicinska ET; Harvard Medical School, Boston, MA 02115, USA; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Jacks TE; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Sullivan RJ; Harvard Medical School, Boston, MA 02115, USA; Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA., Shapiro GI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Clancy TE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA., Perez K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Rubinson DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Ng K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Cleary JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Crawford L; Center for Computational Molecular Biology, Brown University, Providence, RI 02912, USA; Department of Biostatistics, Brown University, Providence, RI 02912, USA; Microsoft Research New England, Cambridge, MA 02142, USA., Manalis SR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Nowak JA; Harvard Medical School, Boston, MA 02115, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Aguirre AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address: andrew_aguirre@dfci.harvard.edu., Shalek AK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address: shalek@mit.edu.

المصدر: Cell [Cell] 2021 Dec 09; Vol. 184 (25), pp. 6119-6137.e26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Microenvironment*, Biomarkers, Tumor/*metabolism , Carcinoma, Pancreatic Ductal/*metabolism , Pancreatic Neoplasms/*metabolism, Adult ; Aged ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Single-Cell Analysis

المؤلفون: Kumar S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Zeng Z; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T. H. Chan School of Public Health, Boston, Massachusetts., Bagati A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Sanz LA; Department of Molecular and Cellular Biology and Genome Center, University of California, Davis, California., Hartono SR; Department of Molecular and Cellular Biology and Genome Center, University of California, Davis, California., Ito Y; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Abderazzaq F; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Hatchi E; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Jiang P; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.; Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Cartwright ANR; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Olawoyin O; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Yale School of Medicine, New Haven, Connecticut., Mathewson ND; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Pyrdol JW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Li MZ; Department of Genetics, Harvard Medical School and Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts., Doench JG; Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Elledge SJ; Department of Genetics, Harvard Medical School and Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts., Chédin F; Department of Molecular and Cellular Biology and Genome Center, University of California, Davis, California., Liu XS; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T. H. Chan School of Public Health, Boston, Massachusetts. kai_wucherpfennig@dfci.harvard.edu xsliu@ds.dfci.harvard.edu., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts. kai_wucherpfennig@dfci.harvard.edu xsliu@ds.dfci.harvard.edu.; Department of Immunology, Harvard Medical School, Boston, Massachusetts.; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

المصدر: Cancer discovery [Cancer Discov] 2021 Aug; Vol. 11 (8), pp. 2050-2071. Date of Electronic Publication: 2021 Mar 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Immune Checkpoint Inhibitors/*pharmacology , Neoplasms/*therapy , Protein-Arginine N-Methyltransferases/*antagonists & inhibitors, Cell Line, Tumor/drug effects ; Humans ; Immunotherapy ; T-Lymphocytes/drug effects

المؤلفون: Turrero García M; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Baizabal JM; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Tran DN; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Peixoto R; Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Wang W; Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Xie Y; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Adam MA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., English LA; Summer Honors Undergraduate Research Program, Harvard Medical School, Boston, MA 02115, USA., Reid CM; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Brito SI; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Harwell CC; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA corey_harwell@hms.harvard.edu.

المصدر: Development (Cambridge, England) [Development] 2020 Nov 16; Vol. 147 (22). Date of Electronic Publication: 2020 Nov 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

مواضيع طبية MeSH: Cerebral Cortex/*metabolism , DNA-Binding Proteins/*metabolism , GABAergic Neurons/*metabolism , Interneurons/*metabolism , Neural Stem Cells/*metabolism , Transcription Factors/*metabolism, Animals ; Cerebral Cortex/cytology ; DNA-Binding Proteins/genetics ; GABAergic Neurons/cytology ; Interneurons/cytology ; Mice ; Neural Stem Cells/cytology ; Transcription Factors/genetics

المؤلفون: Oser MG; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Sabet AH; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA., Gao W; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Chakraborty AA; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Schinzel AC; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA., Jennings RB; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Fonseca R; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA., Bonal DM; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02210, USA., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA., Flaifel A; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Novak JS; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Christensen CL; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA., Zhang H; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York 10016, USA., Herbert ZT; Molecular Biology Core Facilities, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA., Buss EJ; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA., Wong KK; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York 10016, USA., Bronson RT; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts 02215., Nguyen QD; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02210, USA., Signoretti S; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA., Kaelin WG Jr; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Massachusetts 02115, USA.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA.

المصدر: Genes & development [Genes Dev] 2019 Dec 01; Vol. 33 (23-24), pp. 1718-1738. Date of Electronic Publication: 2019 Nov 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation/*genetics , Neuroendocrine Cells/*cytology , Receptors, Notch/*physiology , Retinoblastoma-Binding Protein 2/*metabolism , Signal Transduction/*genetics , Small Cell Lung Carcinoma/*enzymology, Animals ; Basic Helix-Loop-Helix Transcription Factors ; Cell Line ; Cell Transformation, Neoplastic/genetics ; Disease Models, Animal ; Gene Expression Regulation, Neoplastic/genetics ; Histone Demethylases/metabolism ; Humans ; In Vitro Techniques ; Mice ; Neuroendocrine Cells/pathology ; Small Cell Lung Carcinoma/physiopathology