المؤلفون: Rodriguez-Antona, C, Savieo, JL, Lauschke, VM, Sangkuhl, K, Drogemoller, B, Wang, DX, Schaik, RNH, Gilep, AA, Peter, AP, Boone, EC, Ramey, BE, Klein, TE, Whirl-Carrillo, M, Pratt, VM, Gaedigk, A

المصدر: Clinical pharmacology and therapeutics. 112(6):1159-1171

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:149170953

المؤلفون: Zubiaur P; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Universidad Autónoma de Madrid (UAM) and Instituto de Investigación Sanitaria del Hospital Universitario de La Princesa (IP), Madrid, Spain., Rodríguez-Antona C; Pharmacogenomics and Tumor Biomarkers Group, Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM) CSIC/UAM, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras, Valencia, Spain., Boone EC; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA., Daly AK; Translational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Tsermpini EE; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Khasawneh LQ; Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, UAE., Sangkuhl K; Department of Biomedical Data Science, Stanford University, Stanford, California, USA., Duconge J; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico - Medical Sciences Campus, San Juan, Puerto Rico, USA., Botton MR; Transplant Immunology and Personalized Medicine Unit, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.; Postgraduate Program in Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Savieo J; Department of Clinical Operations, AccessDx, Houston, Texas, USA., Nofziger C; PharmGenetix GmbH, Niederalm, Austria., Whirl-Carrillo M; Department of Biomedical Data Science, Stanford University, Stanford, California, USA., Klein TE; Department of Biomedical Data Science, Stanford University, Stanford, California, USA.; Departments of Medicine (BMIR) and Genetics, Stanford University, Stanford, California, USA., Gaedigk A; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Aug 13. Date of Electronic Publication: 2024 Aug 13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

المؤلفون: Gaedigk A; Children's Mercy Research Institute, Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, and University of Missouri-Kansas City School of Medicine, Kansas City, Missouri., Turner AJ; RPRD Diagnostics and Medical College of Wisconsin, Department of Pediatrics, Section on Genomic Pediatrics, Milwaukee, Wisconsin., Moyer AM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Zubiaur P; Clinical Pharmacology Department, Hospital Universitario de la Princesa, Universidad Autónoma de Madrid, Instituto de Investigación Sanitaria de La Princesa, Madrid, Spain., Boone EC; Children's Mercy Research Institute, Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, and University of Missouri-Kansas City School of Medicine, Kansas City, Missouri., Wang WY; Children's Mercy Research Institute, Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, and University of Missouri-Kansas City School of Medicine, Kansas City, Missouri., Broeckel U; RPRD Diagnostics and Medical College of Wisconsin, Department of Pediatrics, Section on Genomic Pediatrics, Milwaukee, Wisconsin., Kalman LV; Division of Laboratory Systems, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: ljk0@cdc.gov.

المصدر: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2024 Jul 18. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100893612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-7811 (Electronic) Linking ISSN: 15251578 NLM ISO Abbreviation: J Mol Diagn Subsets: MEDLINE

المؤلفون: Wagner JB; Ward Family Heart Center, Children's Mercy, Kansas City, MO 64108, USA.; Division of Clinical Pharmacology and Toxicology, Children's Mercy, Kansas City, MO 64108, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA., Abdel-Rahman S; Division of Clinical Pharmacology and Toxicology, Children's Mercy, Kansas City, MO 64108, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA., Raghuveer G; Ward Family Heart Center, Children's Mercy, Kansas City, MO 64108, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA., Gaedigk A; Division of Clinical Pharmacology and Toxicology, Children's Mercy, Kansas City, MO 64108, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA., Boone EC; Division of Clinical Pharmacology and Toxicology, Children's Mercy, Kansas City, MO 64108, USA., Gaedigk R; Division of Clinical Pharmacology and Toxicology, Children's Mercy, Kansas City, MO 64108, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA., Staggs VS; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.; Health Services & Outcomes Research, Children's Mercy, Kansas City, MO 64108, USA., Reed GA; Clinical Pharmacology Shared Resource, University of Kansas Cancer Center, Fairway, KS 66205, USA., Zhang N; Clinical Pharmacology Shared Resource, University of Kansas Cancer Center, Fairway, KS 66205, USA., Leeder JS; Division of Clinical Pharmacology and Toxicology, Children's Mercy, Kansas City, MO 64108, USA.; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.

المصدر: Genes [Genes (Basel)] 2024 Jan 15; Vol. 15 (1). Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

مواضيع طبية MeSH: Hypercholesterolemia*/drug therapy , Hypercholesterolemia*/genetics, Adult ; Humans ; Child ; Atorvastatin/therapeutic use ; Genotype ; Heterozygote ; Genetic Variation ; Liver-Specific Organic Anion Transporter 1/genetics

المؤلفون: Turner AJ; RPRD Diagnostics LLC, Milwaukee, Wisconsin, USA., Haidar CE; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Yang W; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Boone EC; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA., Offer SM; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA., Empey PE; Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, USA., Haddad A; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, USA., Tahir S; Medical College of Wisconsin, School of Pharmacy, Milwaukee, Wisconsin, USA., Scharer G; RPRD Diagnostics LLC, Milwaukee, Wisconsin, USA., Broeckel U; RPRD Diagnostics LLC, Milwaukee, Wisconsin, USA., Gaedigk A; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

المصدر: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13699.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Dihydrouracil Dehydrogenase (NADP)*/metabolism , Population Health*, Child ; Humans ; Haplotypes ; Antimetabolites, Antineoplastic ; Pharmacogenomic Testing ; Genotype

المؤلفون: Zubiaur P; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Instituto Teófilo Hernando, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain.; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA., Soria-Chacartegui P; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Instituto Teófilo Hernando, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain., Boone EC; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA., Prasad B; Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA., Dinh J; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA., Wang WY; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA., Zugbi S; Unit of Innovative Treatments, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina., Rodríguez-Lopez A; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Instituto Teófilo Hernando, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain., González-Iglesias E; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Instituto Teófilo Hernando, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain., Leeder JS; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA., Abad-Santos F; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Instituto Teófilo Hernando, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Gaedigk A; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2023 Nov; Vol. 114 (5), pp. 1033-1042. Date of Electronic Publication: 2023 Aug 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP2C19*/genetics , Cytochrome P-450 Enzyme System*/metabolism, Humans ; Alleles ; Haplotypes

المؤلفون: Gaedigk A; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute, Kansas City, Missouri; University of Missouri-Kansas City School of Medicine, Kansas City, Missouri., Boone EC; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute, Kansas City, Missouri., Turner AJ; RPRD Diagnostics, Milwaukee, Wisconsin; Section on Genomic Pediatrics, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin., van Schaik RHN; Department of Clinical Chemistry/International Federation of Clinical Chemistry and Laboratory Medicine Expert Center Pharmacogenetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Chernova D; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute, Kansas City, Missouri., Wang WY; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute, Kansas City, Missouri., Broeckel U; RPRD Diagnostics, Milwaukee, Wisconsin; Section on Genomic Pediatrics, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin., Granfield CA; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Hodge JC; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Ly RC; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Lynnes TC; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Mitchell MW; Coriell Institute for Medical Research, Camden, New Jersey., Moyer AM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Oliva J; RPRD Diagnostics, Milwaukee, Wisconsin., Kalman LV; Division of Laboratory Systems, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: ljk0@cdc.gov.

المصدر: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2023 Sep; Vol. 25 (9), pp. 655-664. Date of Electronic Publication: 2023 Jun 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100893612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-7811 (Electronic) Linking ISSN: 15251578 NLM ISO Abbreviation: J Mol Diagn Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP3A*/genetics , Genetic Testing*, Humans ; Alleles ; Genotype ; DNA/genetics

المؤلفون: Sy VT; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Boone EC; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Xiao H; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Vierling MM; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Schmitz SF; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Ung Q; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Trawick SS; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA., Hammond TM; School of Biological Sciences, Illinois State University, Normal, IL 61790, USA., Shiu PKT; Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA.

المصدر: G3 (Bethesda, Md.) [G3 (Bethesda)] 2023 Aug 09; Vol. 13 (8).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN: 2160-1836 (Electronic) Linking ISSN: 21601836 NLM ISO Abbreviation: G3 (Bethesda) Subsets: MEDLINE

مواضيع طبية MeSH: Meiosis*/genetics , Neurospora crassa*/metabolism, DNA, Fungal/genetics ; Fungal Proteins/genetics ; DEAD-box RNA Helicases/genetics

المؤلفون: Ramsey LB; Divisions of Clinical Pharmacology and Research in Patient Services, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Gong L; Department of Biomedical Data Science, Stanford University, Stanford, California, USA., Lee SB; Precision Medicine Institute, Macrogen Inc., Seoul, Korea., Wagner JB; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA., Zhou X; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, USA., Sangkuhl K; Department of Biomedical Data Science, Stanford University, Stanford, California, USA., Adams SM; School of Pharmacy, Shenandoah University, Fairfax, Virginia, USA., Straka RJ; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Empey PE; School of Pharmacy and Institute for Precision Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Boone EC; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri, USA., Klein TE; Department of Biomedical Data Science, Stanford University, Stanford, California, USA.; Department of Medicine (BMIR), Stanford University, Stanford, California, USA., Niemi M; Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland., Gaedigk A; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2023 Apr; Vol. 113 (4), pp. 782-793. Date of Electronic Publication: 2022 Jul 27.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects, Humans ; Haplotypes ; Cytochrome P-450 Enzyme System/genetics ; Alleles ; Pharmacogenetics ; Liver-Specific Organic Anion Transporter 1/genetics

المؤلفون: Pratt VM; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Wang WY; Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri., Boone EC; Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri., Broeckel U; RPRD Diagnostics, Milwaukee, Wisconsin; Department of Pediatrics, Section on Genomic Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin., Cody N; Sema4, Stamford, Connecticut; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Edelmann L; Sema4, Stamford, Connecticut; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Gaedigk A; Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri., Lynnes TC; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Medeiros EB; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Moyer AM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Mitchell MW; Coriell Institute for Medical Research, Camden, New Jersey., Scott SA; Department of Pathology, Stanford University, Stanford, California; Clinical Genomics Laboratory, Stanford Healthcare, Palo Alto, California., Starostik P; Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida., Turner A; RPRD Diagnostics, Milwaukee, Wisconsin; Department of Pediatrics, Section on Genomic Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin., Kalman LV; Division of Laboratory Systems, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: ljk0@cdc.gov.

المصدر: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2022 Oct; Vol. 24 (10), pp. 1079-1088. Date of Electronic Publication: 2022 Aug 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100893612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-7811 (Electronic) Linking ISSN: 15251578 NLM ISO Abbreviation: J Mol Diagn Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Testing* , Pharmacogenetics*, Methyltransferases/*genetics , Pyrophosphatases/*genetics, Alleles ; DNA/genetics ; Haplotypes ; Humans