المؤلفون: Khawaja, AA, Chong, DLW, Sahota, J, Mikolasch, TA, Pericleous, C, Ripoll, VM, Booth, HL, Khan, S, Rodriguez-Justo, M, Giles, IP, Porter, JC

مصطلحات موضوعية: respiratory system, respiratory tract diseases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3303535d2098d85e665c69bbda246014
https://openaccess.sgul.ac.uk/id/eprint/112329/9/fimmu-11-02190.pdf

المؤلفون: Khawaja, AA, Sahota, J, Pericleous, C, Ripoll, VM, Chong, DLW, Azzopardi, G, Thomas, LW, Booth, HL, Groves, AM, Ashcroft, M, Giles, I, Porter, JC

المصدر: Thorax; 2017, Vol. 72 Issue: Supplement 3 pA49-A50, 2p

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المؤلفون: Chong, DLW, Sahota, J, Booth, HL, Porter, JC

المصدر: Thorax; 2017, Vol. 72 Issue: Supplement 3 pA49-A49, 1p

المؤلفون: Guillen-Guio B; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK.; Joint first authors., Paynton ML; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Joint first authors., Allen RJ; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Chin DPW; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Donoghue LJ; Genentech, San Francisco, CA, USA., Stockwell A; Genentech, San Francisco, CA, USA., Leavy OC; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Hernandez-Beeftink T; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Reynolds C; National Heart & Lung Institute, Imperial College London, London, UK., Cullinan P; National Heart & Lung Institute, Imperial College London, London, UK., Martinez F; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Booth HL; University College Hospital, University College London, London, UK., Fahy WA; GlaxoSmithKline, London, UK., Hall IP; School of Medicine, University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK., Hart SP; Hull York Medical School, University of Hull, Hull, UK., Hill MR; MRC Population Health Unit, University of Oxford, Oxford, UK., Hirani N; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Hubbard RB; School of Medicine, University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK., McAnulty RJ; Division of Medicine, University College London, London, UK., Millar AB; Bristol Medical School, University of Bristol, Bristol, UK., Navaratnam V; Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.; Queensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, QLD, Australia., Oballa E; GlaxoSmithKline, London, UK., Parfrey H; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK., Saini G; School of Medicine, University of Nottingham, Nottingham, UK., Sayers I; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Whyte MKB; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Adegunsoye A; Department of Medicine, University of Chicago, Chicago, IL, USA., Kaminski N; Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA., Ma SF; Department of Medicine, University of Virginia, Charlottesville, VA, USA., Strek ME; Department of Medicine, University of Chicago, Chicago, IL, USA., Zhang Y; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Fingerlin TE; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, USA., Molina-Molina M; Servei de Pneumologia, Laboratori de Pneumologia Experimental, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain.; Campus de Bellvitge, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Neighbors M; Genentech, San Francisco, CA, USA., Sheng XR; Genentech, San Francisco, CA, USA., Oldham JM; Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA., Maher TM; National Heart and Lung Institute, Imperial College London, London, UK.; Division of Pulmonary and Critical Care Medicine, University of Southern California, Los Angeles, USA., Molyneaux PL; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK., Flores C; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.; Genomics Division, Instituto Tecnologico y de Energias Renovables, Santa Cruz de Tenerife, Spain.; Facultad de Ciencias de la Salud, Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Noth I; Department of Medicine, University of Virginia, Charlottesville, VA, USA., Schwartz DA; Department of Medicine, University of Colorado, Anscuhtz, CO, USA., Yaspan BL; Genentech, San Francisco, CA, USA., Jenkins RG; National Heart and Lung Institute, Imperial College London, London, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK.; Joint senior authors., Hollox EJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.; Joint senior authors.

المصدر: ERJ open research [ERJ Open Res] 2024 Feb 19; Vol. 10 (1). Date of Electronic Publication: 2024 Feb 19 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE

المؤلفون: Leavy OC; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Goemans AF; Department of Population Health Sciences, University of Leicester, Leicester, UK., Stockwell AD; Genentech, California, USA., Allen RJ; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Guillen-Guio B; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Hernandez-Beeftink T; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Adegunsoye A; University of Chicago, Chicago, USA., Booth HL; University College London Hospitals, London, UK., Cullinan P; Imperial College, London, UK., Fahy WA; GlaxoSmithKline, London, UK., Fingerlin TE; National Jewish Health, Colorado, USA., Virk HS; NIHR Leicester Biomedical Research Centre, Leicester, UK., Hall IP; University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK., Hart SP; University of Hull, Hull, UK., Hill MR; University of Oxford, Oxford, UK., Hirani N; University of Edinburgh, Edinburgh, UK., Hubbard RB; University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK., Kaminski N; Yale School of Medicine, Connecticut, USA., Ma SF; University of Virginia, Virginia, USA., McAnulty RJ; University College London, London, UK., Sheng XR; Genentech, California, USA., Millar AB; University of Bristol, Bristol, UK., Molina-Molina M; Servei de Pneumologia, Laboratori de Pneumologia Experimental, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain.; Campus de Bellvitge, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Navaratnam V; Department of Respiratory Medicine, Sir Charles Gardiner Hospital, Perth, Australia.; Centre for Respiratory Research, University of Western Australia, Perth, Australia., Neighbors M; Genentech, California, USA., Parfrey H; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK., Saini G; University of Nottingham, Nottingham, UK., Sayers I; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Strek ME; University of Chicago, Chicago, USA., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Whyte MK; University of Edinburgh, Edinburgh, UK., Zhang Y; University of Pittsburgh, Pittsburgh, USA., Maher TM; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK.; Division of Pulmonary and Critical Care Medicine, University of Southern California, Los Angeles, USA., Molyneaux PL; National Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK.; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK., Oldham JM; University of Michigan, Michigan, USA., Yaspan BL; Genentech, California, USA., Flores C; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.; Genomics Division, Instituto Tecnologico y de Energias Renovables, Santa Cruz de Tenerife, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.; Facultad de Ciencias de la Salud, Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Martinez F; Weill Cornell Medicine, New York, USA., Reynolds CJ; Imperial College, London, UK., Schwartz DA; University of Colorado Medicine, Colorado, USA., Noth I; University of Virginia, Virginia, USA., Jenkins RG; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK.

مؤلفون مشاركون: CleanUP-IPF Investigators of the Pulmonary Trials Cooperative

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Jan 15. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Chong DLW; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.; Institute for Infection and Immunity, St George's University of London, London, United Kingdom., Mikolasch TA; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Sahota J; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Rebeyrol C; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Garthwaite HS; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Booth HL; Interstitial Lung Disease Service, University College London Hospital, London, United Kingdom., Heightman M; Interstitial Lung Disease Service, University College London Hospital, London, United Kingdom., Denneny EK; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., José RJ; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Khawaja AA; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom., Duckworth A; Department of Clinical and Biomedical Science, University of Exeter, Exeter, United Kingdom., Labelle M; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States., Scotton CJ; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.; Department of Clinical and Biomedical Science, University of Exeter, Exeter, United Kingdom., Porter JC; UCL Respiratory, Division of Medicine, University College London, London, United Kingdom.

المصدر: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Oct 01; Vol. 325 (4), pp. L487-L499. Date of Electronic Publication: 2023 Aug 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Idiopathic Pulmonary Fibrosis*/pathology, Humans ; Mice ; Animals ; Lung/pathology ; Transforming Growth Factor beta1/pharmacology ; Fibrosis ; Transforming Growth Factor beta ; Bleomycin/adverse effects ; Inflammation/pathology ; Transforming Growth Factors/adverse effects

المؤلفون: Guillen-Guio B; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Paynton ML; Department of Population Health Sciences, University of Leicester, UK., Allen RJ; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Chin DPW; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Donoghue LJ; Genentech, California, USA., Stockwell A; Genentech, California, USA., Leavy OC; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Hernandez-Beeftink T; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Reynolds C; Imperial College London, London, UK., Cullinan P; Imperial College London, London, UK., Martinez F; Weill Cornell Medicine, New York, USA., Booth HL; University College London Hospitals, London, UK., Fahy WA; GlaxoSmithKline, London, UK., Hall IP; University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK., Hart SP; University of Hull, Hull, UK., Hill MR; University of Oxford, Oxford, UK., Hirani N; University of Edinburgh, Edinburgh, UK., Hubbard RB; University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK., McAnulty RJ; University College London, London, UK., Millar AB; University of Bristol, Bristol, UK., Navaratnam V; Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.; National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.; Queensland Lung Transplant Service, The Prince Charles Hospital, Brisbane, QLD, Australia., Oballa E; GlaxoSmithKline, London, UK., Parfrey H; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK., Saini G; University of Nottingham, Nottingham, UK., Sayers I; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Whyte MKB; University of Edinburgh, Edinburgh, UK., Adegunsoye A; University of Chicago, Chicago, USA., Kaminski N; Yale School of Medicine, Connecticut, USA., Shwu-Fan M; University of Virginia, Virginia, USA., Strek ME; University of Chicago, Chicago, USA., Zhang Y; University of Pittsburgh, Pittsburgh, USA., Fingerlin TE; National Jewish Health, Colorado, USA., Molina-Molina M; Servei de Pneumologia, Laboratori de Pneumologia Experimental, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain.; Campus de Bellvitge, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Neighbors M; Genentech, California, USA., Sheng XR; Genentech, California, USA., Oldham JM; University of Michigan, Michigan, USA., Maher TM; National Heart and Lung Institute, Imperial College London, London, UK.; Division of Pulmonary and Critical Care Medicine, University of Southern California, Los Angeles, USA., Molyneaux PL; National Heart and Lung Institute, Imperial College London, London, UK.; Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK., Flores C; Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.; Genomics Division, Instituto Tecnologico y de Energias Renovables, Santa Cruz de Tenerife, Spain.; Facultad de Ciencias de la Salud, Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Noth I; University of Virginia, Virginia, USA., Schwartz DA; University of Colorado Medicine, Colorado, USA., Yaspan BL; Genentech, California, USA., Jenkins RG; National Heart and Lung Institute, Imperial College London, London, UK., Wain LV; Department of Population Health Sciences, University of Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Hollox EJ; Department of Genetics and Genome Biology, University of Leicester, UK.

مؤلفون مشاركون: CleanUP-IPF Investigators of the Pulmonary Trials Cooperative

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Jul 24. Date of Electronic Publication: 2023 Jul 24.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Thakker C; Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK clare.thakker@nhs.net.; University College London, London, UK., Booth HL; University College London Hospitals NHS Foundation Trust, London, UK., Lambert J; University College London Hospitals NHS Foundation Trust, London, UK.; UCL Cancer Institute, University College London, London, UK., Morgan S; Camden Directorate, North Central London Integrated Care Board, London, UK.; Hampstead Group Practice, London, UK., Checkley AM; Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK.; London School of Hygiene and Tropical Medicine, London, UK.

المصدر: BMJ (Clinical research ed.) [BMJ] 2023 Feb 03; Vol. 380, pp. e070295. Date of Electronic Publication: 2023 Feb 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: British Medical Association Country of Publication: England NLM ID: 8900488 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-1833 (Electronic) Linking ISSN: 09598138 NLM ISO Abbreviation: BMJ Subsets: MEDLINE

مواضيع طبية MeSH: Eosinophilia*/diagnosis, Humans

المؤلفون: Rangaka MX; Institute for Global Health, University College London, London, UK l.rangaka@ucl.ac.uk.; School of Public Health, and Clinical Infectious Disease Research Institute-AFRICA, University of Cape Town, Cape Town, South Africa., Hamada Y; Institute for Global Health, University College London, London, UK., Duong T; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Bern H; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Calvert J; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Francis M; Institute for Global Health, University College London, London, UK., Clarke AL; Centre for Behavioural Medicine, UCL School of Pharmacy, London, UK., Ghanouni A; Centre for Behavioural Medicine, UCL School of Pharmacy, London, UK., Layton C; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Hack V; Institute for Global Health, University College London, London, UK., Owen-Powell E; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Surey J; Institute for Global Health, University College London, London, UK., Sanders K; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Booth HL; North Central London Tuberculosis Service, Whittington Health NHS Trust and University College London Hospitals NHS Foundation Trust, London, UK., Crook A; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, London, UK., Griffiths C; Wolfson Institute for Population Health Barts and the London School of Medicine and Dentistry, Queen Mary University, London, UK., Horne R; Centre for Behavioural Medicine, UCL School of Pharmacy, London, UK., Kunst H; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University, London, UK., Lipman M; UCL Respiratory, Division of Medicine, University College, London, UK.; Royal Free London Hospital NHS Foundation Trust, London, UK., Mandelbaum M; TB Alert, Brighton, UK., White PJ; Modelling and Economics Unit, National Infection Service, Public Health England, London, UK.; MRC Centre for Global Infectious Disease Analysis, Imperial College, London, UK., Zenner D; Institute for Global Health, University College London, London, UK.; Wolfson Institute for Population Health Barts and the London School of Medicine and Dentistry, Queen Mary University, London, UK., Abubakar I; Institute for Global Health, University College London, London, UK.

المصدر: BMJ open [BMJ Open] 2022 Sep 06; Vol. 12 (9), pp. e057717. Date of Electronic Publication: 2022 Sep 06.

نوع المنشور: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

مواضيع طبية MeSH: Rifampin*/therapeutic use , Latent Tuberculosis*/drug therapy, Adult ; Humans ; Adolescent ; Young Adult ; Middle Aged ; Aged ; Isoniazid/therapeutic use ; Antitubercular Agents/therapeutic use ; State Medicine ; United Kingdom ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic