المؤلفون: Jacob Lauwring Andersen, Borbala Gesser, Erik Daa Funder, Christine Juul Fælled Nielsen, Helle Gotfred-Rasmussen, Mads Kirchheiner Rasmussen, Rachel Toth, Kurt Vesterager Gothelf, J. Simon C. Arthur, Lars Iversen, Poul Nissen

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ce38a48876bc4d9fb74081c34943de76

المؤلفون: Lars Iversen, Borbala Gesser, Mads Kirchheiner Rasmussen

المصدر: Psoriasis: Targets and Therapy
Gesser, B, Rasmussen, M K & Iversen, L 2020, ' Dimethyl Fumarate Targets MSK1, RSK1, 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis : A Demonstration of the Effect on Peripheral Blood Mononuclear Cells, Drawn from Two Patients with Severe Psoriasis Before and After Treatment with Dimethyl Fumarate ', Psoriasis (Auckland, N.Z.), vol. 10, pp. 1-11 . https://doi.org/10.2147/PTT.S234151

مصطلحات موضوعية: MSK1, T cell, IKKα, IKKβ, IκBα, Dermatology, Peripheral blood mononuclear cell, DMF, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Rheumatology, medicine, Anisomycin, Original Research, biology, Dimethyl fumarate, Chemistry, Kinase, RSK1, psoriasis, Molecular biology, medicine.anatomical_structure, NF-κB/p65, 030220 oncology & carcinogenesis, Mitogen-activated protein kinase, biology.protein, Phosphorylation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf710a0d888dc28e93ab072fc7160ab
http://europepmc.org/articles/PMC7138529

المؤلفون: Borbala Gesser, Mads Kirchheiner Rasmussen

المصدر: Gesser, B & Rasmussen, M K 2020, ' Psoriatic epidermis expresses high level of inflammatory mediators and the CDK2/4 cyclin-dependent kinases are involved in the regulation of cell-cycle progression in epidermal cells ', British Journal of Dermatology, vol. 182, no. 3, pp. 533-534 . https://doi.org/10.1111/bjd.18713

مصطلحات موضوعية: biology, Epidermis (botany), Cyclin-Dependent Kinase 2, Cell cycle progression, Cyclin-dependent kinase 2, Dermatology, Cyclin-Dependent Kinases, Up-Regulation, Cell biology, Epidermal Cells, Cyclin-dependent kinase, biology.protein, Epidermis, Inflammation Mediators

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1444d55b96e14d83de4c5ea5c98b04
https://doi.org/10.1111/bjd.18713

المؤلفون: Christine J. F. Nielsen, Kurt V. Gothelf, J. Simon C. Arthur, Erik Daa Funder, Helle Gotfred-Rasmussen, Jacob Andersen, Poul Nissen, Mads Kirchheiner Rasmussen, Borbala Gesser, Rachel Toth, Lars Iversen

المصدر: Andersen, J L, Gesser, B, Funder, E D, Nielsen, C J F, Gotfred-Rasmussen, H, Rasmussen, M K, Toth, R, Gothelf, K V, Arthur, J S C, Iversen, L & Nissen, P 2018, ' Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases ', Nature Communications, vol. 9, no. 1, 4344 . https://doi.org/10.1038/s41467-018-06787-w
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Science, Dimethyl Fumarate, Allosteric regulation, General Physics and Astronomy, Crystallography, X-Ray, Binding, Competitive, Ribosomal Protein S6 Kinases, 90-kDa, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, medicine, Transferase, Animals, Humans, Cysteine, Binding site, lcsh:Science, Multidisciplinary, Binding Sites, Dimethyl fumarate, biology, Chemistry, Kinase, General Chemistry, 3. Good health, 030104 developmental biology, HEK293 Cells, Biochemistry, Mechanism of action, Protein kinase domain, Mitogen-activated protein kinase, Mutation, biology.protein, lcsh:Q, medicine.symptom, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a8b9f1ef81620ab1ee814f6c2f8a1b
https://pure.au.dk/portal/da/publications/dimethyl-fumarate-is-an-allosteric-covalent-inhibitor-of-the-p90-ribosomal-s6-kinases(ff27ac53-9409-4678-aaee-a1e66d966606).html

المؤلفون: Jakob Nielsen, Borbala Gesser, Stine Andersen, R.B. Kjellerup, Mads Kirchheiner Rasmussen, Anne Hald Rittig, Claus Johansen, Lars Iversen

المصدر: Rasmussen, M K, Nielsen, J, Kjellerup, R B, Andersen, S M, Rittig, A H, Johansen, C, Iversen, L & Gesser, B 2017, ' Protein phosphatase 2Cδ/Wip1 regulates phospho-p90RSK2 activity in lesional psoriatic skin ', Inflammation Research, vol. 10, pp. 169-180 . https://doi.org/10.2147/JIR.S152869
Journal of Inflammation Research

مصطلحات موضوعية: 0301 basic medicine, Kinase, Chemistry, MIF, Immunology, Phosphatase, Molecular biology, P90 RSK1, 2, Serine, Blot, 030207 dermatology & venereal diseases, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Epidermal growth factor, PP2Cδ/Wip1, Journal Article, Immunology and Allergy, Phosphorylation, Macrophage migration inhibitory factor, Signal transduction, Journal of Inflammation Research, Original Research, EGF, PP2Cδ/ILKAP

وصف الملف: text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5426ee3ed60184ebc977fdc240bc09f7
https://pure.au.dk/portal/da/publications/protein-phosphatase-2cwip1-regulates-phosphop90rsk2-activity-in-lesional-psoriatic-skin(0a805a6d-1685-46dc-ac36-409469e9d207).html

المؤلفون: Kristine Møller, Knud Kragballe, Claus Johansen, Lars Iversen, Jette Lindorff Riis, Christian Grønhøj Larsen, Borbala Gesser

المصدر: Archives of Dermatological Research. 296:195-202

مصطلحات موضوعية: Response element, NF-κB, Dermatology, General Medicine, Biology, Molecular biology, Blot, IκBα, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Cell culture, Transcription (biology), medicine, Keratinocyte, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::06f52bf33a3f3f3aa4639cf224abe2b7
https://doi.org/10.1007/s00403-004-0509-9

المؤلفون: Mads Kirchheiner Rasmussen, Rasmus Boye Kjellerup, Stine Maria Andersen, Anne Hald, Claus Johansen, Lars Iversen, Borbala Gesser

المصدر: Rasmussen, M K, Kjellerup, R B, Andersen, S M, Hald, A, Johansen, C, Iversen, L & Gesser, B 2014, ' Protein phosphatase 2Cδ (PP2Cδ) probably regulates the activity of phospho-p90RSK 2 in the lesional Psoriatic skin ' .
Aarhus University

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9bfacb7d40fc80224c3dc5063a64fc6f
https://pure.au.dk/portal/da/publications/protein-phosphatase-2c-pp2c-probably-regulates-the-activity-of-phospho-p90rsk-2-in-the-lesional-psoriatic-skin(707f780b-b7db-4926-b526-e7768b67e831).html

المؤلفون: Jacob Lauwring Andersen, Poul Nissen, Lars Iversen, Borbala Gesser

المصدر: Andersen, J L, Nissen, P, Iversen, L & Gesser, B Apr. 03 2014, Methods and tools for identification of rsk/msk kinase inhibitors, Patent No. WO2014048442 (A1) .
Aarhus University

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::458e0fad107dfd930e7fe71ed08e7cea
https://pure.au.dk/portal/da/publications/methods-and-tools-for-identification-of-rskmsk-kinase-inhibitors(9f76e0c1-3647-4f2c-a250-f0bf0e9c64bf).html

المؤلفون: Karen Bang, Christian Larsen, Borbala Gesser, Hiroyuki Yoneyama, Kouji Matsushima, Christian Vestergaard

المصدر: Vestergaard, C, Bang, K, Gesser, B, Yoneyama, H, Matsushima, K & Larsen, C G 2000, ' A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin ', Journal of Investigative Dermatology, vol. 115, no. 4, pp. 640-6 . https://doi.org/10.1046/j.1523-1747.2000.00115.x

مصطلحات موضوعية: Keratinocytes, Allergy, Chemokine, Receptors, CCR4, Biopsy, T-Lymphocytes, CCR4, chemokine receptors, Dermatology, Biochemistry, Peripheral blood mononuclear cell, immuno histochemistry, Cell Line, Dermatitis, Atopic, Mice, Chemokine receptor, TNFα, medicine, Animals, Humans, Molecular Biology, Skin, integumentary system, biology, business.industry, Cell Biology, Atopic dermatitis, medicine.disease, medicine.anatomical_structure, lymphocyte recirculation, Chemokines, CC, Immunology, biology.protein, Receptors, Chemokine, CCL27, Chemokine CCL17, business, Keratinocyte, IFNγ

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae3156f1f122a95d313fd95a4660fb9
https://doi.org/10.1046/j.1523-1747.2000.00115.x

المؤلفون: Christian Grønhøj Larsen, Borbala Gesser, Jens Kragskov, S Sindet-Pedersen, Lambros Kostopoulos, Hans Stødkilde-Jørgensen, Steen Lindk˦r Jensen, Shengwel Li

المصدر: International Journal of Oral and Maxillofacial Surgery. 27:386-390

مصطلحات موضوعية: Chemotherapy, Antioxidant, business.industry, medicine.medical_treatment, Soft tissue edema, Tirilazad, Interleukin, Surgical procedures, Tirilazad mesylate, Otorhinolaryngology, Anesthesia, Edema, medicine, Surgery, Oral Surgery, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48c4e85a636b4cc6a621585521f44b28
https://doi.org/10.1016/s0901-5027(98)80070-2