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1دورية أكاديمية
المؤلفون: Jacob Lauwring Andersen, Borbala Gesser, Erik Daa Funder, Christine Juul Fælled Nielsen, Helle Gotfred-Rasmussen, Mads Kirchheiner Rasmussen, Rachel Toth, Kurt Vesterager Gothelf, J. Simon C. Arthur, Lars Iversen, Poul Nissen
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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المؤلفون: Lars Iversen, Borbala Gesser, Mads Kirchheiner Rasmussen
المصدر: Psoriasis: Targets and Therapy
Gesser, B, Rasmussen, M K & Iversen, L 2020, ' Dimethyl Fumarate Targets MSK1, RSK1, 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis : A Demonstration of the Effect on Peripheral Blood Mononuclear Cells, Drawn from Two Patients with Severe Psoriasis Before and After Treatment with Dimethyl Fumarate ', Psoriasis (Auckland, N.Z.), vol. 10, pp. 1-11 . https://doi.org/10.2147/PTT.S234151مصطلحات موضوعية: MSK1, T cell, IKKα, IKKβ, IκBα, Dermatology, Peripheral blood mononuclear cell, DMF, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Rheumatology, medicine, Anisomycin, Original Research, biology, Dimethyl fumarate, Chemistry, Kinase, RSK1, psoriasis, Molecular biology, medicine.anatomical_structure, NF-κB/p65, 030220 oncology & carcinogenesis, Mitogen-activated protein kinase, biology.protein, Phosphorylation
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المؤلفون: Borbala Gesser, Mads Kirchheiner Rasmussen
المصدر: Gesser, B & Rasmussen, M K 2020, ' Psoriatic epidermis expresses high level of inflammatory mediators and the CDK2/4 cyclin-dependent kinases are involved in the regulation of cell-cycle progression in epidermal cells ', British Journal of Dermatology, vol. 182, no. 3, pp. 533-534 . https://doi.org/10.1111/bjd.18713
مصطلحات موضوعية: biology, Epidermis (botany), Cyclin-Dependent Kinase 2, Cell cycle progression, Cyclin-dependent kinase 2, Dermatology, Cyclin-Dependent Kinases, Up-Regulation, Cell biology, Epidermal Cells, Cyclin-dependent kinase, biology.protein, Epidermis, Inflammation Mediators
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المؤلفون: Christine J. F. Nielsen, Kurt V. Gothelf, J. Simon C. Arthur, Erik Daa Funder, Helle Gotfred-Rasmussen, Jacob Andersen, Poul Nissen, Mads Kirchheiner Rasmussen, Borbala Gesser, Rachel Toth, Lars Iversen
المصدر: Andersen, J L, Gesser, B, Funder, E D, Nielsen, C J F, Gotfred-Rasmussen, H, Rasmussen, M K, Toth, R, Gothelf, K V, Arthur, J S C, Iversen, L & Nissen, P 2018, ' Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases ', Nature Communications, vol. 9, no. 1, 4344 . https://doi.org/10.1038/s41467-018-06787-w
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Science, Dimethyl Fumarate, Allosteric regulation, General Physics and Astronomy, Crystallography, X-Ray, Binding, Competitive, Ribosomal Protein S6 Kinases, 90-kDa, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, medicine, Transferase, Animals, Humans, Cysteine, Binding site, lcsh:Science, Multidisciplinary, Binding Sites, Dimethyl fumarate, biology, Chemistry, Kinase, General Chemistry, 3. Good health, 030104 developmental biology, HEK293 Cells, Biochemistry, Mechanism of action, Protein kinase domain, Mitogen-activated protein kinase, Mutation, biology.protein, lcsh:Q, medicine.symptom, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a8b9f1ef81620ab1ee814f6c2f8a1b
https://pure.au.dk/portal/da/publications/dimethyl-fumarate-is-an-allosteric-covalent-inhibitor-of-the-p90-ribosomal-s6-kinases(ff27ac53-9409-4678-aaee-a1e66d966606).html -
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المؤلفون: Jakob Nielsen, Borbala Gesser, Stine Andersen, R.B. Kjellerup, Mads Kirchheiner Rasmussen, Anne Hald Rittig, Claus Johansen, Lars Iversen
المصدر: Rasmussen, M K, Nielsen, J, Kjellerup, R B, Andersen, S M, Rittig, A H, Johansen, C, Iversen, L & Gesser, B 2017, ' Protein phosphatase 2Cδ/Wip1 regulates phospho-p90RSK2 activity in lesional psoriatic skin ', Inflammation Research, vol. 10, pp. 169-180 . https://doi.org/10.2147/JIR.S152869
Journal of Inflammation Researchمصطلحات موضوعية: 0301 basic medicine, Kinase, Chemistry, MIF, Immunology, Phosphatase, Molecular biology, P90 RSK1, 2, Serine, Blot, 030207 dermatology & venereal diseases, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Epidermal growth factor, PP2Cδ/Wip1, Journal Article, Immunology and Allergy, Phosphorylation, Macrophage migration inhibitory factor, Signal transduction, Journal of Inflammation Research, Original Research, EGF, PP2Cδ/ILKAP
وصف الملف: text/html
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5426ee3ed60184ebc977fdc240bc09f7
https://pure.au.dk/portal/da/publications/protein-phosphatase-2cwip1-regulates-phosphop90rsk2-activity-in-lesional-psoriatic-skin(0a805a6d-1685-46dc-ac36-409469e9d207).html -
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المؤلفون: Kristine Møller, Knud Kragballe, Claus Johansen, Lars Iversen, Jette Lindorff Riis, Christian Grønhøj Larsen, Borbala Gesser
المصدر: Archives of Dermatological Research. 296:195-202
مصطلحات موضوعية: Response element, NF-κB, Dermatology, General Medicine, Biology, Molecular biology, Blot, IκBα, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Cell culture, Transcription (biology), medicine, Keratinocyte, Transcription factor
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المؤلفون: Mads Kirchheiner Rasmussen, Rasmus Boye Kjellerup, Stine Maria Andersen, Anne Hald, Claus Johansen, Lars Iversen, Borbala Gesser
المصدر: Rasmussen, M K, Kjellerup, R B, Andersen, S M, Hald, A, Johansen, C, Iversen, L & Gesser, B 2014, ' Protein phosphatase 2Cδ (PP2Cδ) probably regulates the activity of phospho-p90RSK 2 in the lesional Psoriatic skin ' .
Aarhus UniversityURL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9bfacb7d40fc80224c3dc5063a64fc6f
https://pure.au.dk/portal/da/publications/protein-phosphatase-2c-pp2c-probably-regulates-the-activity-of-phospho-p90rsk-2-in-the-lesional-psoriatic-skin(707f780b-b7db-4926-b526-e7768b67e831).html -
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المؤلفون: Jacob Lauwring Andersen, Poul Nissen, Lars Iversen, Borbala Gesser
المصدر: Andersen, J L, Nissen, P, Iversen, L & Gesser, B Apr. 03 2014, Methods and tools for identification of rsk/msk kinase inhibitors, Patent No. WO2014048442 (A1) .
Aarhus UniversityURL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::458e0fad107dfd930e7fe71ed08e7cea
https://pure.au.dk/portal/da/publications/methods-and-tools-for-identification-of-rskmsk-kinase-inhibitors(9f76e0c1-3647-4f2c-a250-f0bf0e9c64bf).html -
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المؤلفون: Karen Bang, Christian Larsen, Borbala Gesser, Hiroyuki Yoneyama, Kouji Matsushima, Christian Vestergaard
المصدر: Vestergaard, C, Bang, K, Gesser, B, Yoneyama, H, Matsushima, K & Larsen, C G 2000, ' A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin ', Journal of Investigative Dermatology, vol. 115, no. 4, pp. 640-6 . https://doi.org/10.1046/j.1523-1747.2000.00115.x
مصطلحات موضوعية: Keratinocytes, Allergy, Chemokine, Receptors, CCR4, Biopsy, T-Lymphocytes, CCR4, chemokine receptors, Dermatology, Biochemistry, Peripheral blood mononuclear cell, immuno histochemistry, Cell Line, Dermatitis, Atopic, Mice, Chemokine receptor, TNFα, medicine, Animals, Humans, Molecular Biology, Skin, integumentary system, biology, business.industry, Cell Biology, Atopic dermatitis, medicine.disease, medicine.anatomical_structure, lymphocyte recirculation, Chemokines, CC, Immunology, biology.protein, Receptors, Chemokine, CCL27, Chemokine CCL17, business, Keratinocyte, IFNγ
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المؤلفون: Christian Grønhøj Larsen, Borbala Gesser, Jens Kragskov, S Sindet-Pedersen, Lambros Kostopoulos, Hans Stødkilde-Jørgensen, Steen Lindk˦r Jensen, Shengwel Li
المصدر: International Journal of Oral and Maxillofacial Surgery. 27:386-390
مصطلحات موضوعية: Chemotherapy, Antioxidant, business.industry, medicine.medical_treatment, Soft tissue edema, Tirilazad, Interleukin, Surgical procedures, Tirilazad mesylate, Otorhinolaryngology, Anesthesia, Edema, medicine, Surgery, Oral Surgery, medicine.symptom, business, medicine.drug