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المؤلفون: Guo H; IGM Biosciences, Mountain View, CA 94043, USA., Ha S; IGM Biosciences, Mountain View, CA 94043, USA., Botten JW; Department of Medicine, Division of Pulmonary Disease and Critical Care Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Department of Microbiology and Molecular Genetics, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT 05405, USA., Xu K; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Strohl WR; IGM Biosciences, Mountain View, CA 94043, USA., Shiver JW; IGM Biosciences, Mountain View, CA 94043, USA., Fu TM; IGM Biosciences, Mountain View, CA 94043, USA.

المصدر: Viruses [Viruses] 2024 Apr 28; Vol. 16 (5). Date of Electronic Publication: 2024 Apr 28.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/immunology , SARS-CoV-2*/genetics , Immune Evasion* , COVID-19*/immunology , COVID-19*/virology , Spike Glycoprotein, Coronavirus*/immunology , Spike Glycoprotein, Coronavirus*/genetics , Spike Glycoprotein, Coronavirus*/metabolism, Humans ; Angiotensin-Converting Enzyme 2/metabolism ; Angiotensin-Converting Enzyme 2/immunology ; Animals ; Evolution, Molecular ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/therapeutic use ; Mutation ; COVID-19 Vaccines/immunology ; Antibodies, Viral/immunology

SCR Organism: SARS-CoV-2 variants

المؤلفون: Guo H; IGM Biosciences, Mountain View, CA, USA., Cho B; IGM Biosciences, Mountain View, CA, USA., Hinton PR; IGM Biosciences, Mountain View, CA, USA., He S; IGM Biosciences, Mountain View, CA, USA., Yu Y; IGM Biosciences, Mountain View, CA, USA., Ramesh AK; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Sivaccumar JP; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ku Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Campo K; IGM Biosciences, Mountain View, CA, USA., Holland S; IGM Biosciences, Mountain View, CA, USA., Sachdeva S; IGM Biosciences, Mountain View, CA, USA., Mensch C; IGM Biosciences, Mountain View, CA, USA., Dawod M; IGM Biosciences, Mountain View, CA, USA., Whitaker A; Cellular, Molecular, and Biomedical Sciences Graduate Program, University of Vermont, Burlington, VT, USA.; Department of Medicine, Division of Pulmonary Disease and Critical Care Medicine, University of Vermont, Burlington, VT, USA., Eisenhauer P; Department of Medicine, Division of Pulmonary Disease and Critical Care Medicine, University of Vermont, Burlington, VT, USA., Falcone A; Department of Medicine, Division of Pulmonary Disease and Critical Care Medicine, University of Vermont, Burlington, VT, USA., Honce R; Department of Medicine, Division of Pulmonary Disease and Critical Care Medicine, University of Vermont, Burlington, VT, USA., Botten JW; Department of Medicine, Division of Pulmonary Disease and Critical Care Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology and Molecular Genetics, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA., Carroll SF; IGM Biosciences, Mountain View, CA, USA., Keyt BA; IGM Biosciences, Mountain View, CA, USA., Womack AW; IGM Biosciences, Mountain View, CA, USA., Strohl WR; IGM Biosciences, Mountain View, CA, USA., Xu K; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA., Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ha S; IGM Biosciences, Mountain View, CA, USA., Shiver JW; IGM Biosciences, Mountain View, CA, USA., Fu TM; IGM Biosciences, Mountain View, CA, USA.

المصدر: Emerging microbes & infections [Emerg Microbes Infect] 2023 Dec; Vol. 12 (2), pp. 2275598. Date of Electronic Publication: 2023 Dec 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

مواضيع طبية MeSH: Coronavirus Infections*/drug therapy , Coronavirus Infections*/prevention & control , Coronavirus Infections*/metabolism , Coronavirus*, Animals ; Mice ; Humans ; Angiotensin-Converting Enzyme 2/metabolism ; Protein Binding ; Spike Glycoprotein, Coronavirus

المؤلفون: Shrestha L; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Lin MJ; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Xie H; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Mills MG; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Mohamed Bakhash SA; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Gaur VP; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Livingston RJ; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Castor J; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Bruce EA; Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont., Botten JW; Department of Medicine, University of Vermont, Burlington, Vermont., Huang ML; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington., Jerome KR; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington., Greninger AL; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Electronic address: agrening@uw.edu., Roychoudhury P; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Electronic address: proychou@uw.edu.

المصدر: The Journal of molecular diagnostics : JMD [J Mol Diagn] 2022 Sep; Vol. 24 (9), pp. 963-976. Date of Electronic Publication: 2022 Jul 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100893612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-7811 (Electronic) Linking ISSN: 15251578 NLM ISO Abbreviation: J Mol Diagn Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/genetics , SARS-CoV-2*/genetics, Genome, Viral ; Humans ; RNA, Viral/genetics ; Whole Genome Sequencing/methods

المؤلفون: Bruce EA; Division of Immunobiology, Department of Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA., Mills MG; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Sampoleo R; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Perchetti GA; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Huang ML; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Despres HW; Department of Microbiology and Molecular Genetics, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA., Schmidt MM; Department of Microbiology and Molecular Genetics, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA., Roychoudhury P; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Shirley DJ; Data Science Department, Faraday, Inc., Burlington, VT, USA., Jerome KR; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Greninger AL; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Botten JW; Division of Immunobiology, Department of Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology and Molecular Genetics, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.

المصدر: EMBO molecular medicine [EMBO Mol Med] 2022 Feb 07; Vol. 14 (2), pp. e15290. Date of Electronic Publication: 2021 Dec 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Humans ; Pandemics ; Polymerase Chain Reaction ; RNA, Viral/genetics

المؤلفون: Victor J; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA., Deutsch J; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA., Whitaker A; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA., Lamkin EN; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA., March A; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA., Zhou P; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Botten JW; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA., Chatterjee N; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05405, USA; University of Vermont Cancer Center, University of Vermont, Burlington, VT, 05405, USA. Electronic address: nimrat.chatterjee@med.uvm.edu.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 19; Vol. 579, pp. 141-145. Date of Electronic Publication: 2021 Sep 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage*, COVID-19/*genetics , Host-Pathogen Interactions/*genetics , SARS-CoV-2/*pathogenicity, Animals ; Ataxia Telangiectasia Mutated Proteins/genetics ; Checkpoint Kinase 1/metabolism ; Chlorocebus aethiops ; Histones/genetics ; Phosphorylation ; Telomere ; Vero Cells

المؤلفون: Rissanen I; Division of Structural Biology, Wellcome Centre for Human Genetics, grid.4991.5University of Oxford, Oxford, United Kingdom.; Institute of Biotechnology and Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Krumm SA; Department of Infectious Diseases, King's College London, London, United Kingdom., Stass R; Division of Structural Biology, Wellcome Centre for Human Genetics, grid.4991.5University of Oxford, Oxford, United Kingdom., Whitaker A; Division of Immunobiology, Department of Medicine, Larner College of Medicine, grid.59062.38University of Vermont, Burlington, Vermont, USA.; Cellular, Molecular, and Biomedical Sciences Graduate Program, grid.59062.38University of Vermont, Burlington, Vermont, USA., Voss JE; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA., Bruce EA; Division of Immunobiology, Department of Medicine, Larner College of Medicine, grid.59062.38University of Vermont, Burlington, Vermont, USA.; Department of Microbiology and Molecular Genetics, Larner College of Medicine, grid.59062.38University of Vermont, Burlington, Vermont, USA., Rothenberger S; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Kunz S; Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA.; Ragon Institute of MGH, Harvard, and MIT, Cambridge, Massachusetts, USA., Huiskonen JT; Division of Structural Biology, Wellcome Centre for Human Genetics, grid.4991.5University of Oxford, Oxford, United Kingdom.; Institute of Biotechnology and Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Botten JW; Division of Immunobiology, Department of Medicine, Larner College of Medicine, grid.59062.38University of Vermont, Burlington, Vermont, USA.; Department of Microbiology and Molecular Genetics, Larner College of Medicine, grid.59062.38University of Vermont, Burlington, Vermont, USA., Bowden TA; Division of Structural Biology, Wellcome Centre for Human Genetics, grid.4991.5University of Oxford, Oxford, United Kingdom., Doores KJ; Department of Infectious Diseases, King's College London, London, United Kingdom.

المصدر: MBio [mBio] 2021 Aug 31; Vol. 12 (4), pp. e0253120. Date of Electronic Publication: 2021 Jul 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Neutralizing/*chemistry , Antibodies, Neutralizing/*immunology , Antibodies, Viral/*chemistry , Hantaan virus/*genetics , Hantaan virus/*immunology , Viral Envelope Proteins/*immunology, Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Viral/immunology ; Epitope Mapping ; Female ; HEK293 Cells ; Hantavirus Infections/immunology ; Humans ; Immunization ; Rabbits

المؤلفون: Drayman N; Pritzker School for Molecular Engineering, The University of Chicago, Chicago, IL, USA. tays@uchicago.edu nirdra@uchicago.edu., DeMarco JK; Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville, Louisville, KY, USA., Jones KA; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Azizi SA; Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Froggatt HM; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA., Tan K; Department of Medicine, Division of Immunobiology, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA., Maltseva NI; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA., Chen S; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Cellular Screening Center, The University of Chicago, Chicago, IL, USA., Nicolaescu V; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA., Dvorkin S; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA., Furlong K; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA., Kathayat RS; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Firpo MR; Pritzker School for Molecular Engineering, The University of Chicago, Chicago, IL, USA.; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA., Mastrodomenico V; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA., Bruce EA; Cellular Screening Center, The University of Chicago, Chicago, IL, USA.; Department of Medicine, Division of Immunobiology, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, USA., Schmidt MM; Department of Medicine, Division of Immunobiology, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, USA., Jedrzejczak R; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA., Muñoz-Alía MÁ; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Molecular Medicine, Mayo Clinic, Rochester, MN, USA., Schuster B; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Pritzker School for Molecular Engineering, The University of Chicago, Chicago, IL, USA., Nair V; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Pritzker School for Molecular Engineering, The University of Chicago, Chicago, IL, USA., Han KY; Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville, Louisville, KY, USA.; Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA., O'Brien A; Department of Pharmaceutical Sciences, College of Pharmacy, Biophysics Core at Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA.; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA., Tomatsidou A; Department of Medicine, Division of Immunobiology, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA., Meyer B; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France., Vignuzzi M; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA.; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France., Missiakas D; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA., Botten JW; Cellular Screening Center, The University of Chicago, Chicago, IL, USA.; Department of Medicine, Division of Immunobiology, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT, USA., Brooke CB; Department of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Lee H; Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Department of Pharmaceutical Sciences, College of Pharmacy, Biophysics Core at Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA., Baker SC; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.; Pritzker School for Molecular Engineering, The University of Chicago, Chicago, IL, USA.; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA., Mounce BC; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA., Heaton NS; Institut Pasteur, Viral Populations and Pathogenesis Unit, Centre National de la Recherche Scientifique UMR 3569, Paris, France.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA., Severson WE; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville, Louisville, KY, USA., Palmer KE; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville, Louisville, KY, USA., Dickinson BC; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA.; Department of Chemistry, The University of Chicago, Chicago, IL, USA., Joachimiak A; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, USA.; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA.; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA., Randall G; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA., Tay S; Department of Microbiology, Ricketts Laboratory, University of Chicago, Chicago, IL, USA. tays@uchicago.edu nirdra@uchicago.edu.; Pritzker School for Molecular Engineering, The University of Chicago, Chicago, IL, USA.

المصدر: Science (New York, N.Y.) [Science] 2021 Aug 20; Vol. 373 (6557), pp. 931-936. Date of Electronic Publication: 2021 Jul 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Drug Treatment*, Antiviral Agents/*pharmacology , Coronavirus 3C Proteases/*antagonists & inhibitors , Coronavirus OC43, Human/*drug effects , Cysteine Proteinase Inhibitors/*pharmacology , SARS-CoV-2/*drug effects , Thiazoles/*pharmacology, A549 Cells ; Animals ; Antiviral Agents/chemistry ; Antiviral Agents/metabolism ; Antiviral Agents/therapeutic use ; Benzamides ; COVID-19/virology ; Catalytic Domain ; Coronavirus 3C Proteases/chemistry ; Coronavirus 3C Proteases/metabolism ; Coronavirus OC43, Human/physiology ; Cysteine Proteinase Inhibitors/chemistry ; Cysteine Proteinase Inhibitors/metabolism ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; Mice ; Mice, Transgenic ; Microbial Sensitivity Tests ; Piperidines ; Pyridines ; SARS-CoV-2/enzymology ; SARS-CoV-2/physiology ; Thiazoles/chemistry ; Thiazoles/metabolism ; Thiazoles/therapeutic use ; Viral Load/drug effects ; Virus Replication/drug effects

المؤلفون: Montgomery TL; Department of Biomedical and Health Sciences, College of Nursing and Health Sciences, University of Vermont, Burlington, Vermont, USA., Paavola M; Center for Health and Wellbeing, University of Vermont, Burlington, Vermont, USA., Bruce EA; Department of Microbiology & Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.; Translational Global Infectious Disease Research Center, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA., Botten JW; Department of Microbiology & Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.; Translational Global Infectious Disease Research Center, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.; Division of Immunobiology, Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA., Crothers JW; Translational Global Infectious Disease Research Center, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.; Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont, USA., Krementsov DN; Department of Biomedical and Health Sciences, College of Nursing and Health Sciences, University of Vermont, Burlington, Vermont, USA.

المصدر: Journal of clinical microbiology [J Clin Microbiol] 2021 Jun 18; Vol. 59 (7), pp. e0072321. Date of Electronic Publication: 2021 Jun 18.

نوع المنشور: Letter

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-660X (Electronic) Linking ISSN: 00951137 NLM ISO Abbreviation: J Clin Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Clinical Laboratory Techniques ; DNA ; Humans ; Laboratories ; Reverse Transcriptase Polymerase Chain Reaction

المؤلفون: Tu HA; Department of Microbiology and Molecular Genetics, Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Cellular, Molecular, and Biomedical Sciences Graduate Program, University of Vermont, Burlington, VT 05405, USA., Nivarthi UK; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA., Graham NR; Department of Microbiology and Molecular Genetics, Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Eisenhauer P; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Delacruz MJ; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA., Pierce KK; Department of Microbiology and Molecular Genetics, Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Whitehead SS; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Boyson JE; Cellular, Molecular, and Biomedical Sciences Graduate Program, University of Vermont, Burlington, VT 05405, USA.; Department of Surgery, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Botten JW; Department of Microbiology and Molecular Genetics, Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Cellular, Molecular, and Biomedical Sciences Graduate Program, University of Vermont, Burlington, VT 05405, USA.; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Kirkpatrick BD; Department of Microbiology and Molecular Genetics, Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA., Durbin AP; Department of International Health, Center for Immunization Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., deSilva AM; Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA., Diehl SA; Department of Microbiology and Molecular Genetics, Vaccine Testing Center, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.; Cellular, Molecular, and Biomedical Sciences Graduate Program, University of Vermont, Burlington, VT 05405, USA.

المصدر: Cell reports. Medicine [Cell Rep Med] 2020 Dec 22; Vol. 1 (9), pp. 100155. Date of Electronic Publication: 2020 Dec 22 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med

مواضيع طبية MeSH: B-Lymphocytes/*immunology , Dengue Vaccines/*immunology , Flavivirus/*immunology , Vaccines, Attenuated/*immunology, Adaptive Immunity/immunology ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Dengue/immunology ; Dengue Virus/immunology ; Humans ; Plasma Cells/immunology