المؤلفون: Donald William Ludovici, Gilles Bignan, Carsten Schubert, Erwin Fraiponts, Karine Smans, Norbert Esser, Danielle Peeters, Michael H. Parker, Maxwell D. Cummings, Peter Vermeulen, Lieven Meerpoel, Sabine De Breucker, Tianbao Lu, Luc Van Nuffel, Richard Alexander, Bruce L. Grasberger, James R. Bischoff, Christian Rocaboy, Ron Gilissen, Christophe Meyer, Boudewijn Janssens, Peter J. Connolly

المصدر: Bioorganic & Medicinal Chemistry Letters. 28:2159-2164

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Cell type, Oral treatment, Clinical Biochemistry, Cancer therapy, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Oral administration, Drug Discovery, medicine, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Organic Chemistry, Imidazoles, Cancer, Neoplasms, Experimental, medicine.disease, Bioavailability, Fatty Acid Synthase, Type I, Fatty acid synthase, 030104 developmental biology, Drug Design, 030220 oncology & carcinogenesis, Pharmacodynamics, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd313b43d21d3b1660d7723e4aead6d0
https://doi.org/10.1016/j.bmcl.2018.05.014

المؤلفون: Timothy Perera, Tinne Verhulst, Boudewijn Janssens, Glen Clack, Marion Libouban, Eleonora Jovcehva, Souichi Ogata, Berthold Wroblowski, Desiree De Lange, Laurence Anne Mevellec, Tianbao Lu

المصدر: Cancer Research. 78:4791-4791

مصطلحات موضوعية: Cancer Research, Kinase, business.industry, medicine.medical_treatment, Cancer, Tumor initiation, medicine.disease, Targeted therapy, Metastasis, Oncology, medicine, Cancer research, Erlotinib, business, IC50, medicine.drug, EGFR inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::075f06cdf2ceac4069f4bb5df1069441
https://doi.org/10.1158/1538-7445.am2018-4791

المؤلفون: A Mariën, Manfred Jung, Patrick Rene Angibaud, Wim Floren, Michel Janicot, T. Geerts, K. Van Emelen, Boudewijn Janssens, Luc Andries, J. Van Dun, Peter King, J. Arts, L Janssen, Dana L. Johnson, R W Tuman

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, Cancer Research, Administration, Oral, Angiogenesis Inhibitors, Hydroxamic Acids, Histones, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, HDAC, Neoplasms, Tumor Cells, Cultured, JNJ-16241199, Sulfones, Enzyme Inhibitors, Promoter Regions, Genetic, Histone deacetylase inhibitor, Immunohistochemistry, Isoenzymes, Oncology, medicine.drug, Cyclin-Dependent Kinase Inhibitor p21, medicine.drug_class, small molecule, Mice, Nude, Antineoplastic Agents, Biology, HDAC inhibitor, In vivo, Cell Line, Tumor, Panobinostat, R306465, medicine, Animals, Humans, Vorinostat, Cell Proliferation, Dose-Response Relationship, Drug, Cell growth, HDAC6, Xenograft Model Antitumor Assays, anticancer agent, Rats, Enzyme Activation, Histone Deacetylase Inhibitors, Disease Models, Animal, chemistry, Acetylation, Cancer research, Histone deacetylase, Translational Therapeutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f68efcc8c75d57eb34dbb5ff9cf3937
https://doi.org/10.1038/sj.bjc.6604025

المؤلفون: Peter ten Holte, Boudewijn Janssens, Sandrine Gaurrand, Janine Arts, Jacky van Gompel, Virginie Sophie Poncelet, Patrick Angibaud, Ann Marien, Hans De Winter, Bruno Roux, An Aerts, Verdonck Marc Gustaaf Celine, Jacky Van Dun, Luc Van Hijfte, Kristof Van Emelen, Isabelle Noëlle Constance Pilatte, Eddy Jean Edgard Freyne, Wim Floren, Michel Janicot, Sven Franciscus Anna Van Brandt, Jean-Michel Argoullon, Laurence Queguiner

المصدر: European Journal of Medicinal Chemistry. 40:597-606

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Stereochemistry, medicine.drug_class, Hydroxamic Acids, Inhibitory Concentration 50, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Cell Proliferation, Pharmacology, Histone deacetylase 5, Hydroxamic acid, Molecular Structure, biology, HDAC11, Histone deacetylase 2, HDAC10, Organic Chemistry, Histone deacetylase inhibitor, General Medicine, Histone Deacetylase Inhibitors, Pyrimidines, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Female, Histone deacetylase, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdbd08dce8f647012c95f1517777f59
https://doi.org/10.1016/j.ejmech.2005.01.008

المؤلفون: Boudewijn Janssens, Ian Stansfield, Hillary Millar, Yannick Ligny, Marc Salvati, Matthias Versele, Lieven Meerpoel, Gross Gerhard Max, Ricardo Attar, Sophie Nocquet-Thibault, Charles P. Theuer, Csoka Imre Christian, James P. Edwards, Tamara Geerts, Lut Janssen, Edgar Jacoby, Virginie Tronel, Y R F Simonnet, Laurie Lenox, Olivier Querolle, Nathalie Claudie Isabelle Amblard, Sriram Balasubramanian, Wim Floren, Virginie Sophie Poncelet

المصدر: Cancer Research. 77:4199-4199

مصطلحات موضوعية: TRAF3, Cancer Research, Chemistry, Kinase, RELB, Cell, medicine.disease, Lymphoma, medicine.anatomical_structure, Oncology, Ubiquitin ligase complex, medicine, Cancer research, Signal transduction, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::feb3cdad510f1cd0028dfe83b41470b9
https://doi.org/10.1158/1538-7445.am2017-4199

المؤلفون: Danielle Peeters, Michael H. Parker, Donald William Ludovici, Christophe Meyer, Richard Alexander, Bruce L. Grasberger, S. de Breucker, Christian Rocaboy, Norbert Esser, Lieven Meerpoel, Tianbao Lu, Ronaldus Arnodus Hendrika Joseph Gilissen, Maxwell D. Cummings, Peter J. Connolly, James R. Bischoff, Gilles Bignan, Erwin Fraiponts, Boudewijn Janssens, Karine Smans, Carsten Schubert

المصدر: European Journal of Cancer. 50:141-142

مصطلحات موضوعية: Cancer Research, Oncology, Chemistry, Stereochemistry, Domain (software engineering)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b2caf22b40b42ea7e9026627bb170080
https://doi.org/10.1016/s0959-8049(14)70556-8

المؤلفون: R. Van Ginckel, Boudewijn Janssens, R. De Coster, Myriam Callens, Luc Wouters, N. Goeminne

المصدر: Cancer Chemotherapy and Pharmacology. 38:21-28

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, medicine.drug_class, 9,10-Dimethyl-1,2-benzanthracene, Ovariectomy, Administration, Oral, Toxicology, Effective dose (radiation), Rats, Sprague-Dawley, chemistry.chemical_compound, Oral administration, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Pharmacology (medical), Enzyme Inhibitors, Aromatase, skin and connective tissue diseases, Progesterone, Pharmacology, Aromatase inhibitor, Estradiol, biology, Aromatase Inhibitors, business.industry, 7,12-Dimethylbenz[a]anthracene, Androstenedione, Estrogen Antagonists, Mammary Neoplasms, Experimental, Luteinizing Hormone, Triazoles, Rats, Disease Models, Animal, Tamoxifen, Endocrinology, Oncology, chemistry, Carcinogens, Vorozole, biology.protein, Female, Growth inhibition, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749cfa752565b78acaa39869eae0b360
https://doi.org/10.1007/s002800050442

المؤلفون: Lieven Meerpoel, Gilles Bignan, Luc Van Nuffel, Peter Vermeulen, Ron Gilissen, Tianbao Lu, Max Cummings, Christophe Meyer, Bruce L. Grasberger, Peter J. Connolly, Michael H. Parker, Erwin Fraiponts, Richard Alexander, Karine Smans, Boudewijn Janssens, Danielle Peeters, Norbert Esser, Donald William Ludovici, Carsten Schubert, James R. Bischoff, Sabine De Breucker

المصدر: Cancer Research. 74:4747-4747

مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, biology, Cell growth, Chemistry, Cancer, Pharmacology, medicine.disease, medicine.disease_cause, Fatty acid synthase, Enzyme, Oncology, Apoptosis, Cancer cell, medicine, biology.protein, Carcinogenesis, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bbc77f2de582fc793cad2cd350548d6d
https://doi.org/10.1158/1538-7445.am2014-4747

المؤلفون: Carsten Schubert, Ron Gilissen, Bruce L. Grasberger, Christophe Meyer, Peter J. Connolly, Sabine De Breucker, Luc Van Nuffel, Norbert Esser, James R. Bischoff, Michael H. Parker, Donald William Ludovici, Erwin Fraiponts, Boudewijn Janssens, Danielle Peeters, Karine Smans, Tianbao Lu, Peter Vermeulen, Lieven Meerpoel, Gilles Bignan

المصدر: Cancer Research. 74:2535-2535

مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, biology, In vitro, Palmitic acid, chemistry.chemical_compound, Fatty acid synthase, Enzyme, Oncology, Biochemistry, Biosynthesis, chemistry, In vivo, Cell culture, biology.protein, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5984cccf305d5033564ca0577f95f99e
https://doi.org/10.1158/1538-7445.am2014-2535

المؤلفون: Nathalie C. Bellocq, Frederik Tack, Wim Floren, Suzie H. Pun, Michel Janicot, Gregory S. Jensen, Boudewijn Janssens, Jianjun Cheng, Mark E. Davis, Annette Bakker, Brendan H. Grubbs, Marcus E. Brewster

المصدر: Cancer biologytherapy. 3(7)

مصطلحات موضوعية: Male, Cancer Research, Biodistribution, Adamantane, Deoxyribozyme, Gene delivery, Polyethylene Glycols, chemistry.chemical_compound, Mice, Drug Delivery Systems, Neoplasms, Animals, Infusions, Parenteral, Infusions, Intravenous, Pharmacology, chemistry.chemical_classification, Cyclodextrins, Drug Carriers, Cyclodextrin, Oligonucleotide, Gene Transfer Techniques, Transferrin, DNA, Catalytic, Oncology, chemistry, Biochemistry, Nucleic acid, Biophysics, Molecular Medicine, DNA, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4984575e56e2635c8a1553ac7c043c45
https://pubmed.ncbi.nlm.nih.gov/15136766