المؤلفون: Guo, J, Anderson, M G, Tapang, P, Palma, J P, Rodriguez, L E, Niquette, A, Li, J, Bouska, J J, Wang, G, Semizarov, D, Albert, D H, Donawho, C K, Glaser, K B, Shah, O J^{Aff1, IDtpj200820_cor14}

المصدر: The Pharmacogenomics Journal. 9(2):90-102

المؤلفون: Dai, Y., Guo, Y., Frey, R. R., Ji, Z., Curtin, M. L., Ahmed, A. A., Albert, D. H., Arnold, L., Arries, S. S., Barlozzari, T., Bauch, J. L., Bouska, J. J., Bousquet, P. F., Cunha, G. A., Glaser, K. B., Guo, J., Li, J., Marcotte, P. A., Marsh, K. C., Moskey, M. D., Pease, L. J., Stewart, K. D., Stoll, V. S., Tapang, P., Wishart, N., Davidsen, S. K., Michaelides, M. R.

المصدر: Journal of Medicinal Chemistry; September 2005, Vol. 48 Issue: 19 p6066-6083, 18p

المؤلفون: Wada, C. K., Holms, J. H., Curtin, M. L., Dai, Y., Florjancic, A. S., Garland, R. B., Guo, Y., Heyman, H. R., Stacey, J. R., Steinman, D. H., Albert, D. H., Bouska, J. J., Elmore, I. N., Goodfellow, C. L., Marcotte, P. A., Tapang, P., Morgan, D. W., Michaelides, M. R., Davidsen, S. K.

المصدر: Journal of Medicinal Chemistry; January 2002, Vol. 45 Issue: 1 p219-232, 14p

المؤلفون: Michaelides, M. R., Dellaria, J. F., Gong, J., Holms, J. H., Bouska, J. J., Stacey, J., Wada, C. K., Heyman, H. R., Curtin, M. L., Guo, Y.

المصدر: Bioorganic & Medicinal Chemistry Letters; 2001, Vol. 11 Issue: 12 p1553-1556, 4p

المؤلفون: Curtin ML; Cancer Research Area, Abbott Laboratories, Dept. 47J, Bldg. AP10, 100 Abbott Park Road, Abbott Park, IL 60064, USA. mike.curtin@abbott.com, Florjancic AS, Heyman HR, Michaelides MR, Garland RB, Holms JH, Steinman DH, Dellaria JF, Gong J, Wada CK, Guo Y, Elmore IB, Tapang P, Albert DH, Magoc TJ, Marcotte PA, Bouska JJ, Goodfellow CL, Bauch JL, Marsh KC, Morgan DW, Davidsen SK

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2001 Jun 18; Vol. 11 (12), pp. 1557-60.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Matrix Metalloproteinase Inhibitors*, Biphenyl Compounds/*pharmacokinetics , Hydroxamic Acids/*pharmacokinetics, Administration, Oral ; Animals ; Antineoplastic Agents/blood ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacokinetics ; Area Under Curve ; Biological Availability ; Biphenyl Compounds/blood ; Biphenyl Compounds/chemical synthesis ; Cell Division/drug effects ; Dogs ; Enzyme Inhibitors/blood ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/pharmacokinetics ; Half-Life ; Haplorhini ; Hydroxamic Acids/blood ; Hydroxamic Acids/chemical synthesis ; Inhibitory Concentration 50 ; Injections, Intravenous ; Metabolic Clearance Rate ; Neoplasms, Experimental/drug therapy ; Rats ; Structure-Activity Relationship ; Tumor Cells, Cultured

المؤلفون: Nienaber VL; Department of Structural Biology, Abbott Laboratories, Abbott Park, IL 60064-6098, USA. vicki.nienaber@abbott.com, Richardson PL, Klighofer V, Bouska JJ, Giranda VL, Greer J

المصدر: Nature biotechnology [Nat Biotechnol] 2000 Oct; Vol. 18 (10), pp. 1105-8.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Print ISSN: 1087-0156 (Print) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Crystallography, X-Ray* , Drug Design*, Antineoplastic Agents/*chemistry , Drug Evaluation, Preclinical/*methods , Enzyme Inhibitors/*chemistry , Urokinase-Type Plasminogen Activator/*antagonists & inhibitors, Administration, Oral ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacology ; Enzyme Inhibitors/administration & dosage ; Enzyme Inhibitors/pharmacology ; Ligands ; Macromolecular Substances ; Molecular Conformation ; Naphthalenes/chemistry ; Naphthalenes/pharmacology ; Quinolines/chemistry ; Quinolines/pharmacology ; Structure-Activity Relationship ; Time Factors ; Urokinase-Type Plasminogen Activator/metabolism

المؤلفون: Sheppard GS; Department 47J, AP-10, Abbott Laboratory, Abbott Park, Illinois 60064, USA., Florjancic AS, Giesler JR, Xu L, Guo Y, Davidsen SK, Marcotte PA, Elmore I, Albert DH, Magoc TJ, Bouska JJ, Goodfellow CL, Morgan DW, Summers JB

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1998 Nov 17; Vol. 8 (22), pp. 3251-6.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Matrix Metalloproteinase Inhibitors*, Gelatinases/*antagonists & inhibitors , Hydroxamic Acids/*pharmacology , Ketones/*pharmacology , Metalloendopeptidases/*antagonists & inhibitors , Protease Inhibitors/*pharmacology, Matrix Metalloproteinase 1 ; Matrix Metalloproteinase 2 ; Matrix Metalloproteinase 7 ; Structure-Activity Relationship

المؤلفون: Bouska JJ; Immunoscience Research, Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, IL 60064, USA., Bell RL, Goodfellow CL, Stewart AO, Brooks CD, Carter GW

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 1997 Sep; Vol. 25 (9), pp. 1032-8.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Print Cited Medium: Print ISSN: 0090-9556 (Print) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Glucuronosyltransferase/*analysis , Hydroxyurea/*analogs & derivatives , Lipoxygenase Inhibitors/*metabolism , Microsomes, Liver/*metabolism, Animals ; Half-Life ; Humans ; Hydroxyurea/metabolism ; Hydroxyurea/pharmacokinetics ; Macaca fascicularis ; Metabolic Clearance Rate ; Structure-Activity Relationship