لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Slavish PJ; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Cuypers MG; Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Rimmer MA; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Abdolvahabi A; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Jeevan T; Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Kumar G; Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Jarusiewicz JA; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Vaithiyalingam S; Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Jones JC; Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Bowling JJ; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Price JE; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., DuBois RM; Baskin School of Engineering, University of California at Santa Cruz, Santa Cruz, CA, 95064, USA., Min J; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Webby RJ; Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Rankovic Z; Departments of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Electronic address: zoran.rankovic@stjude.org., White SW; Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Electronic address: stevew.white@stjude.org.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2023 Feb 05; Vol. 247, pp. 115035. Date of Electronic Publication: 2022 Dec 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: HIV Integrase Inhibitors* , Orthomyxoviridae* , Influenza, Human*/drug therapy , Dibenzothiepins*/pharmacology , Dibenzothiepins*/therapeutic use, Humans ; RNA-Dependent RNA Polymerase ; Pyridones/pharmacology ; Pyridones/therapeutic use ; Endonucleases ; Triazines/pharmacology ; Antiviral Agents/pharmacology

المؤلفون: Palacios G; Department of Immunology, St Jude Children's Research Hospital, Memphis, TN - 38105-3678, USA., Bowling JJ; Department of Chemical Biology & Therapeutics, St Jude Children's Research Hospital, Memphis, TN - 38105-3678, USA., Abdolvahabi A; Department of Chemical Biology & Therapeutics, St Jude Children's Research Hospital, Memphis, TN - 38105-3678, USA.

المصدر: Future medicinal chemistry [Future Med Chem] 2019 Mar; Vol. 11 (6), pp. 495-498. Date of Electronic Publication: 2019 Mar 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Future Science Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery/*methods , Lipidomics/*methods , Metabolomics/*methods, Animals ; Humans ; Mass Spectrometry/methods ; Metabolic Networks and Pathways/drug effects

المؤلفون: Perera WH; Ironstone Separations, Inc., Etta, Oxford, MS 38627, USA., Ghiviriga I; Department of Chemistry, University of Florida, Gainesville, FL 32611, USA., Rodenburg DL; Ironstone Separations, Inc., Etta, Oxford, MS 38627, USA., Alves K; Ironstone Separations, Inc., Etta, Oxford, MS 38627, USA., Bowling JJ; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Avula B; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA., Khan IA; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA; Division of Pharmacognosy, Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS 38677, USA., McChesney JD; Ironstone Separations, Inc., Etta, Oxford, MS 38627, USA. Electronic address: jdmcchesney@yahoo.com.

المصدر: Phytochemistry [Phytochemistry] 2017 Mar; Vol. 135, pp. 106-114. Date of Electronic Publication: 2016 Dec 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Diterpenes/*isolation & purification , Glycosides/*isolation & purification , Stevia/*chemistry, Diterpenes/chemistry ; Diterpenes, Kaurane ; Glycosides/chemistry ; Molecular Structure ; Saponins/analysis ; Triterpenes/analysis

المؤلفون: Cassilly CD; Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America., Maddox MM; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, United States of America., Cherian PT; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, United States of America., Bowling JJ; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, United States of America., Hamann MT; Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Medical University of South Carolina, Charleston, South Carolina, United States of America., Lee RE; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, United States of America., Reynolds TB; Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America.

المصدر: PloS one [PLoS One] 2016 May 16; Vol. 11 (5), pp. e0154932. Date of Electronic Publication: 2016 May 16 (Print Publication: 2016).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Antifungal Agents/*pharmacology , Depsipeptides/*pharmacology , Piperidones/*pharmacology , Spiro Compounds/*pharmacology, Antifungal Agents/chemistry ; CDPdiacylglycerol-Serine O-Phosphatidyltransferase/antagonists & inhibitors ; CDPdiacylglycerol-Serine O-Phosphatidyltransferase/metabolism ; Candida albicans/drug effects ; Depsipeptides/chemistry ; Drug Antagonism ; Drug Discovery ; Drug Resistance, Fungal ; High-Throughput Screening Assays ; Microbial Sensitivity Tests ; Molecular Structure ; Piperidones/chemistry ; Spiro Compounds/chemistry

المؤلفون: Zhang J; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Bowling JJ; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Smithson D; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.; Genentech, San Francisco, CA, USA., Clark J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Jacob MR; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Khan SI; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Tekwani BL; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.; Department of Biomolecular Sciences and Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Connelly M; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Samoylenko V; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.; Keiser University, West Palm Beach, FL, USA., Ibrahim MA; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Zaki MA; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.; Beni-Suef University, Beni-Suef, Egypt., Wang M; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Hester JP; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Tu Y; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Jeffries C; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Twarog N; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Shelat AA; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Walker LA; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA.; Department of Biomolecular Sciences and Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA., Muhammad I; National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA. milias@olemiss.edu., Guy RK; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. kip.guy@stjude.org.

المصدر: Malaria journal [Malar J] 2016 May 10; Vol. 15 (1), pp. 270. Date of Electronic Publication: 2016 May 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials/*pharmacology , Biological Products/*pharmacology , Plant Extracts/*pharmacology , Plants/*chemistry , Plasmodium falciparum/*drug effects, Antimalarials/isolation & purification ; Antimalarials/toxicity ; Biological Products/isolation & purification ; Biological Products/toxicity ; Cell Survival/drug effects ; Cells, Cultured ; Epithelial Cells/drug effects ; Fibroblasts/drug effects ; High-Throughput Screening Assays ; Humans ; Plant Extracts/isolation & purification ; Plant Extracts/toxicity

المؤلفون: Li H; College of Pharmacy, Pusan National University, Busan 609-735, Republic of Korea. Electronic address: lihuayue@naver.com., Bowling JJ; Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, Oxford, MN 38677, USA. Electronic address: bowlingjj@gmail.com., Su M; College of Pharmacy, Pusan National University, Busan 609-735, Republic of Korea. Electronic address: smz0310@163.com., Hong J; College of Pharmacy, Kyung Hee University, Seoul 130-701, Republic of Korea. Electronic address: jhong@khu.ac.kr., Lee BJ; College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address: lbj@nmr.snu.ac.kr., Hamann MT; Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, Oxford, MN 38677, USA. Electronic address: mthamann@olemiss.edu., Jung JH; College of Pharmacy, Pusan National University, Busan 609-735, Republic of Korea. Electronic address: jhjung@pusan.ac.kr.

المصدر: Biochimica et biophysica acta [Biochim Biophys Acta] 2014 Mar; Vol. 1840 (3), pp. 977-84. Date of Electronic Publication: 2013 Nov 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-3002 (Print) Linking ISSN: 00063002 NLM ISO Abbreviation: Biochim Biophys Acta Subsets: MEDLINE

مواضيع طبية MeSH: Cystine-Knot Miniproteins/*chemistry , Porifera/*chemistry, Administration, Oral ; Amino Acid Sequence ; Animals ; Calcium/metabolism ; Drug Discovery ; Models, Molecular ; Molecular Sequence Data ; Protein Stability ; Protein Structure, Secondary ; Protein Structure, Tertiary

المؤلفون: Li H; College of Pharmacy, Pusan National University , Busan 609-735, Republic of Korea., Su M, Hamann MT, Bowling JJ, Kim HS, Jung JH

المصدر: Journal of natural products [J Nat Prod] 2014 Feb 28; Vol. 77 (2), pp. 304-10. Date of Electronic Publication: 2014 Feb 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Pharmacognosy Country of Publication: United States NLM ID: 7906882 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6025 (Electronic) Linking ISSN: 01633864 NLM ISO Abbreviation: J Nat Prod Subsets: MEDLINE

مواضيع طبية MeSH: Cystine/*chemistry , Peptides/*chemistry , Porifera/*chemistry, Amino Acid Sequence ; Animals ; Chymotrypsin/metabolism ; Crystallography, X-Ray ; Humans ; Marine Biology ; Models, Molecular ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Pancreatic Elastase/metabolism ; Pepsin A/metabolism ; Protein Conformation ; Stereoisomerism ; Trypsin/metabolism