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1دورية أكاديمية
المؤلفون: Renger G. Tiessen, Ciara A. Kennedy, Bradley T. Keller, Nancy Levin, Lisette Acevedo, Bronislava Gedulin, Andre A. van Vliet, Alejandro Dorenbaum, Melissa Palmer
المصدر: BMC Gastroenterology, Vol 18, Iss 1, Pp 1-17 (2018)
مصطلحات موضوعية: Apical sodium-dependent bile acid transporter, Bile acids, Clinical pharmacology, Non-alcoholic steatohepatitis, Non-alcoholic fatty liver disease, Phase 1 clinical trial, Diseases of the digestive system. Gastroenterology, RC799-869
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: B. Ganesh Bhat, Stephen R. Rapp, Judith A. Beaudry, Nida Napawan, Dustie N. Butteiger, Kerri A. Hall, Christopher L. Null, Yi Luo, Bradley T. Keller
المصدر: Journal of Lipid Research, Vol 44, Iss 9, Pp 1614-1621 (2003)
مصطلحات موضوعية: apolipoprotein E, cholesterol, low density lipoprotein, apical sodium codependent bile acid transporter, farnesoid X receptor, enterohepatic, Biochemistry, QD415-436
وصف الملف: electronic resource
Relation: http://www.sciencedirect.com/science/article/pii/S0022227520337238; https://doaj.org/toc/0022-2275
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3دورية أكاديمية
المؤلفون: Dawn E. Telford, Jane Y. Edwards, Sara M. Lipson, Brian Sutherland, P.Hugh R. Barrett, John R. Burnett, Elaine S. Krul, Bradley T. Keller, Murray W. Huff
المصدر: Journal of Lipid Research, Vol 44, Iss 5, Pp 943-952 (2003)
مصطلحات موضوعية: bile acid reabsorption, atorvastatin, kinetics, cholesterol 7α-hydroxylase, LDL receptor, Biochemistry, QD415-436
وصف الملف: electronic resource
Relation: http://www.sciencedirect.com/science/article/pii/S0022227520311408; https://doaj.org/toc/0022-2275
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4
المؤلفون: Tiffany Shi, Alexander Miethke, Wujuan Zhang, Kenneth D.R. Setchell, Anil G. Jegga, Shana White, Shiva Kumar Shanmukhappa, Celine S. Lages, Amy Taylor, Rebekah Karns, Bradley T. Keller, Stephenson Nkinin, Julia Simmons
المصدر: Hepatology. 63:512-523
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Hepatology, Organic anion transporter 1, biology, Bilirubin, Phospholipid, medicine.disease, Proinflammatory cytokine, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Endocrinology, chemistry, Cholestasis, Biochemistry, Fibrosis, Internal medicine, Toxicity, medicine, biology.protein, 030211 gastroenterology & hepatology
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المؤلفون: Andre van Vliet, Bradley T. Keller, Melissa Palmer, Alejandro Dorenbaum, Ciara Kennedy, Renger G. Tiessen, Lisette Acevedo, Bronislava Gedulin, Nancy Levin
المصدر: BMC Gastroenterology
BMC Gastroenterology, Vol 18, Iss 1, Pp 1-17 (2018)مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, Placebo-controlled study, Benzothiepins, Gastroenterology, LUM002, chemistry.chemical_compound, Feces, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Homeostasis, Glycosides, SHP626, Non-alcoholic steatohepatitis, Membrane Glycoproteins, Symporters, General Medicine, Middle Aged, Tolerability, 030211 gastroenterology & hepatology, Female, Apical sodium-dependent bile acid transporter, Clinical pharmacology, Research Article, Adult, medicine.medical_specialty, Adolescent, Organic Anion Transporters, Sodium-Dependent, Placebo, Bile Acids and Salts, 03 medical and health sciences, Young Adult, Pharmacokinetics, Double-Blind Method, Internal medicine, Type 2 diabetes mellitus, medicine, Humans, lcsh:RC799-869, Adverse effect, Cholestenones, Aged, Cholesterol, business.industry, Volixibat, Phase 1 clinical trial, medicine.disease, Lipid Metabolism, Bile acids, 030104 developmental biology, chemistry, Diabetes Mellitus, Type 2, Pharmacodynamics, lcsh:Diseases of the digestive system. Gastroenterology, Steatohepatitis, business
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المؤلفون: Jeffrey T. Borenstein, Toni A. Steiner, Bradley T. Keller, Craig M. Neville, Eric Park, Ernest S. Kim, Katherine M. Kulig, Hideaki Shimada, Hiroyuki Eda, Krupali Patel
المصدر: Digestive Diseases and Sciences. 57:1152-1162
مصطلحات موضوعية: Liver Cirrhosis, Male, Time Factors, Stress fiber, Physiology, medicine.medical_treatment, Primary Cell Culture, Nanofibers, Biological Factors, Transforming Growth Factor beta2, Cell Movement, Stress Fibers, Gene expression, Cell Adhesion, Hepatic Stellate Cells, medicine, Animals, Rats, Wistar, Endothelin-1, Chemistry, Gene Expression Profiling, Growth factor, Gastroenterology, Quiescent state, hemic and immune systems, Anatomy, Phenotype, Rats, Cell biology, Membrane, Nanofiber, Hepatic stellate cell, Plastics
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7
المصدر: The Journal of Nutritional Biochemistry. 16:722-728
مصطلحات موضوعية: Male, Simvastatin, medicine.medical_specialty, Combination therapy, Lipoproteins, Endocrinology, Diabetes and Metabolism, Guinea Pigs, Clinical Biochemistry, Organic Anion Transporters, Sodium-Dependent, Reductase, Biology, Biochemistry, Bile Acids and Salts, Cyclic N-Oxides, chemistry.chemical_compound, Internal medicine, Cholesterylester transfer protein, medicine, Animals, RNA, Messenger, Cholesterol 7-alpha-Hydroxylase, Molecular Biology, Glycoproteins, chemistry.chemical_classification, Messenger RNA, Nutrition and Dietetics, Symporters, Reverse Transcriptase Polymerase Chain Reaction, Cholesterol, Cholesterol, LDL, Cholesterol Ester Transfer Proteins, Diet, Enzymes, Enzyme, Endocrinology, Liver, chemistry, biology.protein, Hydroxymethylglutaryl CoA Reductases, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, Carrier Proteins, Homeostasis, Tropanes, medicine.drug
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8Discovery of Potent, Nonsystemic Apical Sodium-Codependent Bile Acid Transporter Inhibitors (Part 2)
المؤلفون: Miller Raymond E, Wei Huang, Horng-Chih Huang, Jay S. Trivedi, Scott R. Both, Nigam P. Rath, David B. Reitz, Deborah A. Mischke, Len F. Lee, Samuel J. Tremont, Steve R. Rapp, Danny J. Garland, Claude Jones, Banerjee Shyamal C, Matthew W. Mahoney, Theresa Fletcher, Michael B. Tollefson, Karen Regina, Emily J. Reinhard, Grace M. Wagner, Mark E. Smith, Judy Beaudry, J.-H Li, Kevin C. Glenn, Bradley T. Keller, Robert E. Manning, Kevin J. Koeller, Joe R. Schuh, Kolodziej Steve A, William F. Vernier, Carpenter Andrew J, Ching-Cheng Wang
المصدر: Journal of Medicinal Chemistry. 48:5853-5868
مصطلحات موضوعية: Male, Taurocholic Acid, medicine.drug_class, medicine.medical_treatment, Sodium, Organic Anion Transporters, Sodium-Dependent, chemistry.chemical_element, Benzothiepins, Chemical synthesis, Absorption, Cell Line, Steroid, Bile Acids and Salts, Structure-Activity Relationship, chemistry.chemical_compound, X-Ray Diffraction, Cricetinae, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Rats, Wistar, Mesocricetus, Symporters, Bile acid, Chemistry, Reabsorption, Anticholesteremic Agents, Humidity, Stereoisomerism, Taurocholic acid, Rats, Biochemistry, Symporter, Molecular Medicine, Crystallization
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9
المؤلفون: Khaldoun G. Tarakji, Bradley T. Keller, Ming Zhang, Eric J. Topol, A. Michael Lincoff, Farhad Forudi, Zhongmin Zhou, Mark E. Smith, Xiaorong Zhou, Alane T. Koki, Kai Wang, Marc S. Penn
المصدر: Journal of Cardiovascular Pharmacology. 45:61-67
مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Intimal hyperplasia, Arteriosclerosis, medicine.medical_treatment, Femoral artery, Matrix Metalloproteinase Inhibitors, Iliac Artery, Proinflammatory cytokine, Restenosis, medicine.artery, medicine, Animals, Cyclooxygenase Inhibitors, Chemokine CCL2, Pharmacology, Neointimal hyperplasia, Sulfonamides, Hyperplasia, Cyclooxygenase 2 Inhibitors, biology, business.industry, Stent, medicine.disease, Matrix Metalloproteinase 9, Celecoxib, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Cyclooxygenase 1, biology.protein, Matrix Metalloproteinase 2, Pyrazoles, Female, Stents, Rabbits, Cyclooxygenase, Tunica Intima, Cardiology and Cardiovascular Medicine, business, Angioplasty, Balloon, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0c8ee1f46464b414982aecdd47c48f
https://doi.org/10.1097/00005344-200501000-00011 -
10
المؤلفون: Yi Luo, Bradley T. Keller, B. Ganesh Bhat, Kerri A. Hall, Stephen R. Rapp, Christopher L. Null, Nida Napawan, Dustie N Butteiger, Judith A. Beaudry
المصدر: Journal of Lipid Research, Vol 44, Iss 9, Pp 1614-1621 (2003)
مصطلحات موضوعية: Male, Apolipoprotein E, medicine.medical_specialty, Arteriosclerosis, medicine.drug_class, Organic Anion Transporters, Sodium-Dependent, QD415-436, Cholesterol 7 alpha-hydroxylase, Biochemistry, Bile Acids and Salts, Cyclic N-Oxides, Mice, chemistry.chemical_compound, Apolipoproteins E, Endocrinology, Ileum, Cricetinae, Internal medicine, Atorvastatin, medicine, Animals, Humans, Pyrroles, Enzyme Inhibitors, Cells, Cultured, apolipoprotein E, Mice, Knockout, SLC10A2, Symporters, Bile acid, biology, Cholesterol, Reverse cholesterol transport, cholesterol, Biological Transport, Cell Biology, G protein-coupled bile acid receptor, apical sodium codependent bile acid transporter, chemistry, Heptanoic Acids, enterohepatic, biology.protein, lipids (amino acids, peptides, and proteins), Farnesoid X receptor, low density lipoprotein, Gene Deletion, farnesoid X receptor, Tropanes
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b168626b9bb4449febd1be6583ba2604
https://doi.org/10.1194/jlr.m200469-jlr200
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