المؤلفون: Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Song X; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Childress AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Skaggs EM; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Byrd AL; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Gosser CM; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Esoe DP; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., DuCote TJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Plaugher DR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Lukyanchuk A; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536., Goettl RA; Markey Cancer Center, University of Kentucky, Lexington KY 40536., Liu J; Markey Cancer Center, University of Kentucky, Lexington KY 40536.; Department of Internal Medicine, University of Kentucky, Lexington KY 40536., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536.; Markey Cancer Center, University of Kentucky, Lexington KY 40536.; Corresponding author.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 23. Date of Electronic Publication: 2024 Jul 23.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: DuCote TJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Song X; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Chen F; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Plaugher DR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Childress AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Gellert AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Skaggs EM; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Qu X; Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia., Liu J; Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia.; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia., Liu J; Department of Cancer Biostatistics, University of Kentucky, Lexington, Kentucky., Li F; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York University, New York, New York., Wong KK; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York University, New York, New York., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky.

المصدر: Cancer research communications [Cancer Res Commun] 2024 Feb 13; Vol. 4 (2), pp. 388-403.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung* , Carcinoma, Squamous Cell*/drug therapy , Lung Neoplasms*/drug therapy, Humans ; Mice ; Animals ; Cell Line ; Enzyme Inhibitors ; Lung/pathology ; Tumor Microenvironment ; Enhancer of Zeste Homolog 2 Protein/genetics

المؤلفون: Evans K; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Dabrowska C; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Ng ME; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY, USA., Lee JH; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK. jhl62@cam.ac.uk.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. jhl62@cam.ac.uk.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2805, pp. 3-18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Organoids*/cytology , Lung*/cytology , Cell Differentiation*, Animals ; Mice ; Cell Culture Techniques/methods ; Cell Separation/methods ; Epithelial Cells/cytology ; Stem Cells/cytology ; Stem Cells/metabolism ; Phenotype ; Trachea/cytology ; Coculture Techniques/methods

المؤلفون: Chen F; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA.; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, P. R. China., Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Lee JH; Wellcome - MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA. cfbrainson@uky.edu.; Markey Cancer Center, University of Kentucky, Lexington, KY, USA. cfbrainson@uky.edu.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2805, pp. 19-30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Organoids*/cytology , Lung*/cytology , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology, Animals ; Mice ; Cell Culture Techniques, Three Dimensional/methods ; Humans ; Cell Culture Techniques/methods ; Epithelial Cells/cytology ; Transduction, Genetic/methods

المؤلفون: W-M Fan T; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA. Electronic address: twmfan@gmail.com., Islam JMM; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA., Higashi RM; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA., Lin P; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA., Lane AN; Center for Environmental and System Biochemistry, University of Kentucky, Lexington, Kentucky, USA; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, USA; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105485. Date of Electronic Publication: 2023 Nov 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Enhancer of Zeste Homolog 2 Protein*/genetics , Enhancer of Zeste Homolog 2 Protein*/metabolism , Metabolic Reprogramming*/genetics, Humans ; Cell Line, Tumor ; Polycomb Repressive Complex 2/antagonists & inhibitors ; Polycomb Repressive Complex 2/genetics ; A549 Cells ; Adenocarcinoma of Lung/physiopathology ; Gene Knockdown Techniques ; Glycolysis/genetics ; Citric Acid Cycle/genetics ; Pentose Phosphate Pathway/genetics ; Purine Nucleotides/genetics ; Gene Expression Regulation, Neoplastic

المؤلفون: DuCote TJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Skaggs EM; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky., Bocklage TJ; Markey Cancer Center, University of Kentucky, Lexington, Kentucky; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky., Allison DB; Markey Cancer Center, University of Kentucky, Lexington, Kentucky; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky; Markey Cancer Center, University of Kentucky, Lexington, Kentucky. Electronic address: cfbrainson@uky.edu.

المصدر: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2023 Aug; Vol. 103 (8), pp. 100176. Date of Electronic Publication: 2023 May 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/pathology, Humans ; Animals ; Mice ; Hematoxylin ; Artificial Intelligence ; Tumor Microenvironment ; Eosine Yellowish-(YS)

المؤلفون: DuCote TJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Song X; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Chen F; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Plaugher DR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Childress AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Edgin AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA., Qu X; Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23219 USA., Liu J; Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23219 USA.; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23219 USA., Liu J; Department of Cancer Biostatistics, University of Kentucky, Lexington KY 40536 USA., Li F; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York University, New York, NY 10016 USA., Wong KK; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York University, New York, NY 10016 USA., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington KY 40536 USA.; Markey Cancer Center, University of Kentucky, Lexington KY 40536 USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 08. Date of Electronic Publication: 2023 Jun 08.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Burikhanov R; Department of Radiation Medicine, College of Medicine, University of Kentucky Lexington, Kentucky, USA., Ganguly S; Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky Lexington, Kentucky, USA., Ellingson S; Department of Internal Medicine, College of Medicine, University of Kentucky Lexington, Kentucky, USA., Sviripa VM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky Lexington, Kentucky, USA., Araujo N; Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky Lexington, Kentucky, USA., Li S; Department of Medicine, Division of Oncology, Washington University St. Louis, Missouri, USA., Venkatraman P; Tata Memorial Centre-Advanced Centre for Treatment Research and Education in Cancer Navi Mumbai, Maharashtra, India., Rao M; Department of Pharmacy Practice, Center for Translational Research, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education Manipal, Karnataka, India., Choughule A; Tata Memorial Centre-Advanced Centre for Treatment Research and Education in Cancer Navi Mumbai, Maharashtra, India., Brainson CF; Department of Toxicology and Cancer Biology, College of Medicine, University of Kentucky Lexington, Kentucky, USA.; Markey Cancer Center, University of Kentucky Lexington, Kentucky, USA., Zhan CG; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky Lexington, Kentucky, USA., Spielmann HP; Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky Lexington, Kentucky, USA., Watt DS; Department of Molecular and Cellular Biochemistry, College of Medicine, University of Kentucky Lexington, Kentucky, USA., Govindan R; Department of Medicine, Division of Oncology, Washington University St. Louis, Missouri, USA., Rangnekar VM; Department of Radiation Medicine, College of Medicine, University of Kentucky Lexington, Kentucky, USA.; Markey Cancer Center, University of Kentucky Lexington, Kentucky, USA.

المصدر: American journal of cancer research [Am J Cancer Res] 2023 Mar 15; Vol. 13 (3), pp. 976-991. Date of Electronic Publication: 2023 Mar 15 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101549944 Publication Model: eCollection Cited Medium: Print ISSN: 2156-6976 (Print) Linking ISSN: 21566976 NLM ISO Abbreviation: Am J Cancer Res Subsets: PubMed not MEDLINE

المؤلفون: Chen F; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA.; Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, 510060, Guangzhou, P. R. China., Byrd AL; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Liu J; Department of Internal Medicine, University of Kentucky, Lexington, KY, 40536, USA., Flight RM; Department of Molecular & Cellular Biochemistry, University of Kentucky, Lexington, KY, 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., DuCote TJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Song X; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Edgin AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Lukyanchuk A; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Dixon DT; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Gosser CM; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Esoe DP; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Jayswal RD; Markey Cancer Center Biostatistics and Bioinformatics Shared Resource Facility, Lexington, KY, 40536, USA., Orkin SH; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA., Moseley HNB; Department of Molecular & Cellular Biochemistry, University of Kentucky, Lexington, KY, 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Wang C; Department of Internal Medicine, University of Kentucky, Lexington, KY, 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA. cfbrainson@uky.edu.; Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA. cfbrainson@uky.edu.

المصدر: Nature communications [Nat Commun] 2023 Jan 20; Vol. 14 (1), pp. 336. Date of Electronic Publication: 2023 Jan 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/genetics , Adenocarcinoma of Lung*/drug therapy , Adenocarcinoma of Lung*/genetics, Humans ; Proto-Oncogene Proteins p21(ras)/genetics ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Polycomb Repressive Complex 2/genetics ; Polycomb Repressive Complex 2/metabolism ; Polycomb-Group Proteins/genetics ; Epigenesis, Genetic ; Forkhead Transcription Factors/genetics

المؤلفون: Byrd AL; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Qu X; Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA., Lukyanchuk A; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Liu J; Department of Internal Medicine, University of Kentucky, Lexington, KY, USA., Chen F; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Naughton KJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., DuCote TJ; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Song X; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Bowman HC; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Zhao Y; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Edgin AR; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA., Wang C; Department of Internal Medicine, University of Kentucky, Lexington, KY, USA; Markey Cancer Center, University of Kentucky, Lexington, KY, USA., Liu J; Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, USA; Markey Cancer Center, University of Kentucky, Lexington, KY, USA. Electronic address: cfbrainson@uky.edu.

المصدر: Stem cell reports [Stem Cell Reports] 2023 Jan 10; Vol. 18 (1), pp. 289-304. Date of Electronic Publication: 2022 Dec 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

مواضيع طبية MeSH: Polycomb Repressive Complex 2*/genetics , Pulmonary Disease, Chronic Obstructive*/genetics, Humans ; Mice ; Animals ; Cell Differentiation/genetics ; Enhancer of Zeste Homolog 2 Protein/genetics ; Embryonic Stem Cells ; Polycomb Repressive Complex 1