المؤلفون: Tatjana Schwarz, Christian Drosten, Andreas Wieser, Lara Maria Jeworowski, Barner M, Meng Yuan, Yuanzi Hua, Harald Prüss, Jakob Kreye, Homeyer Ma, Tabea M. Eser, Marie Luisa Schmidt, Stöffler L, Gänzer H, Ramberger M, Dietmar Schmitz, Victor M. Corman, van Hoof S, Elisa Sanchez-Sendin, Hans-Christian Kornau, Horler J, Michael Hoelscher, Ian A. Wilson, Foverskov Rasmussen H, Désirée Kunkel, Wardenburg Nv, Guenter Weiss, Inge Kroidl, S. M. Reincke, Wenli Yu, Brandl Se, Christof Geldmacher, Henry Tien, Huo S

مصطلحات موضوعية: chemistry.chemical_classification, Coronavirus disease 2019 (COVID-19), biology, chemistry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), biology.protein, Antibody, Beta (finance), Virology, Virus, Neutralization, Antigenic drift, Amino acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd6387a4f7e618b564d520c58dcff189
https://doi.org/10.1101/2021.09.30.462420

المؤلفون: Reincke SM; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Yuan M; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Kornau HC; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Neuroscience Research Center (NWFZ), Cluster NeuroCure, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Corman VM; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin., van Hoof S; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Sánchez-Sendin E; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Ramberger M; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Yu W; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Hua Y; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Tien H; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Schmidt ML; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany., Schwarz T; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany., Jeworowski LM; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany., Brandl SE; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Rasmussen HF; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Homeyer MA; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Stöffler L; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Barner M; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Kunkel D; Flow and Mass Cytometry Core Facility, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany., Huo S; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Horler J; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., von Wardenburg N; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Kroidl I; Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (LMU), Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany., Eser TM; Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (LMU), Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany., Wieser A; Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (LMU), Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany., Geldmacher C; Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (LMU), Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany., Hoelscher M; Division of Infectious Diseases and Tropical Medicine, Medical Center of the University of Munich (LMU), Germany.; German Center for Infection Research (DZIF), partner site Munich, Germany., Gänzer H; Department of Internal Medicine, BKH Schwaz, Schwaz, Austria., Weiss G; Department of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria., Schmitz D; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Neuroscience Research Center (NWFZ), Cluster NeuroCure, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Drosten C; Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany., Prüss H; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany., Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Kreye J; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin, Berlin, Germany.; Helmholtz Innovation Lab BaoBab (Brain Antibody-omics and B-cell Lab), Berlin, Germany.; Department of Pediatric Neurology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

المصدر: Science (New York, N.Y.) [Science] 2022 Feb 18; Vol. 375 (6582), pp. 782-787. Date of Electronic Publication: 2022 Jan 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Cross Reactions*, Antibodies, Neutralizing/*immunology , Antibodies, Viral/*immunology , COVID-19/*immunology , SARS-CoV-2/*immunology , Spike Glycoprotein, Coronavirus/*immunology, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/genetics ; Antibodies, Viral/genetics ; Antibodies, Viral/metabolism ; Antigenic Drift and Shift ; COVID-19/virology ; Female ; Humans ; Male ; Middle Aged ; Neutralization Tests ; Protein Binding ; Protein Domains ; Protein Interaction Domains and Motifs ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism

SCR Organism: SARS-CoV-2 variants