المؤلفون: Zhao, XL, Howell, KA, He, SH, Brannan, JM, Wec, AZ, Davidson, E, Turner, HL, Chiang, CI, Lei, L, Fels, JM, Vu, H, Shulenin, S, Turonis, AN, Kuehne, AI, Liu, GD, Ta, M, Wang, YM, Sundling, C, Xiao, YL, Spence, JS, Doranz, BJ, Holtsberg, FW, Ward, AB, Chandran, K, Dye, JM, Qiu, XG, Li, YX, Aman, MJ

المصدر: Cell. 169(5):891

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:135838332

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المؤلفون: Husby ML; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA., Amiar S; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA., Prugar LI; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., David EA; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Plescia CB; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Huie KE; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., Brannan JM; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., Dye JM; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., Pienaar E; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA.; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA., Stahelin RV; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA.

المصدر: EMBO reports [EMBO Rep] 2022 Nov 07; Vol. 23 (11), pp. e51709. Date of Electronic Publication: 2022 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

مواضيع طبية MeSH: Hemorrhagic Fever, Ebola*/metabolism , Ebolavirus*/physiology, Animals ; Phosphatidylserines/metabolism ; Fendiline/metabolism ; Viral Matrix Proteins/metabolism ; Virus Assembly ; Cluster Analysis ; Mammals/metabolism

المؤلفون: Tenny S; University of Nebraska Medical Center, Brannan JM; GDB Research and Statistical Consulting, Brannan GD; GDB Research and Statistical Consulting/McLaren Macomb Hospital

المصدر: 2022 Jan.

المصدر: In: StatPearls

نوع المنشور: Study Guide

بيانات الدورية: Publisher: StatPearls Publishing Cited Medium: Internet

المؤلفون: Bayot ML; Adventist University of the Philippines-College of Medicine; Cavite State University-Med Tech Dept., Brannan GD; GDB Research and Statistical Consulting/McLaren Macomb Hospital, Brannan JM; GDB Research and Statistical Consulting, Tenny S; University of Nebraska Medical Center

المصدر: 2022 Jan.

المصدر: In: StatPearls

نوع المنشور: Review

بيانات الدورية: Publisher: StatPearls Publishing Cited Medium: Internet

المؤلفون: Beitzel BF; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Radoshitzky SR; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA.; The Geneva Foundation, Tacoma, WA 98402, USA., Di Paola N; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Brannan JM; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Kimmel D; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Caviness K; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Soloveva V; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Yu S; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Fort Detrick, Frederick, MD 21702, USA., Postnikova EN; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Fort Detrick, Frederick, MD 21702, USA., Finch CL; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Fort Detrick, Frederick, MD 21702, USA., Liu H; Department of Medicine, Brigham and Women's Hospital and Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Prugar L; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Bakken R; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Dye JM; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Kugelman JR; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Cunningham JM; Department of Medicine, Brigham and Women's Hospital and Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Sanchez-Lockhart M; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA., Kuhn JH; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Fort Detrick, Frederick, MD 21702, USA., Palacios G; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Frederick, MD 21702, USA.

المصدر: Viruses [Viruses] 2021 Oct 06; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Ebolavirus/*genetics , Hemorrhagic Fever, Ebola/*genetics , Reverse Genetics/*methods, Cell Line ; Disease Outbreaks ; Ebolavirus/immunology ; Ebolavirus/pathogenicity ; Genome, Viral/genetics ; Genotype ; Hemorrhagic Fever, Ebola/metabolism ; Hemorrhagic Fever, Ebola/virology ; Humans ; Medical Countermeasures ; Phenotype ; Phylogeny

المؤلفون: Verdonck S; Medicinal Chemistry, Rega Institute for Medical Research , KU Leuven , Herestraat 49-bus 1041 , 3000 Leuven , Belgium., Pu SY; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, and Department of Microbiology and Immunology , Stanford University School of Medicine , Stanford , California 94305 , United States., Sorrell FJ; Nuffield Department of Clinical Medicine, Target Discovery Institute (TDI) and Structural Genomics Consortium (SGC) , University of Oxford , Old Road Campus, Roosevelt Drive , Oxford OX3 7DQ , U.K., Elkins JM; Nuffield Department of Clinical Medicine, Target Discovery Institute (TDI) and Structural Genomics Consortium (SGC) , University of Oxford , Old Road Campus, Roosevelt Drive , Oxford OX3 7DQ , U.K.; Structural Genomics Consortium , Universidade Estadual de Campinas , Cidade Universitária Zeferino Vaz, Av. Dr. André Tosello, 550 , Barão Geraldo, Campinas , São Paulo 13083-886 , Brazil., Froeyen M; Medicinal Chemistry, Rega Institute for Medical Research , KU Leuven , Herestraat 49-bus 1041 , 3000 Leuven , Belgium., Gao LJ; Medicinal Chemistry, Rega Institute for Medical Research , KU Leuven , Herestraat 49-bus 1041 , 3000 Leuven , Belgium., Prugar LI; US Army Medical Research Institute of Infectious Diseases , Viral Immunology Branch , Fort Detrick , Maryland 21702 , United States., Dorosky DE; US Army Medical Research Institute of Infectious Diseases , Viral Immunology Branch , Fort Detrick , Maryland 21702 , United States., Brannan JM; US Army Medical Research Institute of Infectious Diseases , Viral Immunology Branch , Fort Detrick , Maryland 21702 , United States., Barouch-Bentov R; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, and Department of Microbiology and Immunology , Stanford University School of Medicine , Stanford , California 94305 , United States., Knapp S; Nuffield Department of Clinical Medicine, Target Discovery Institute (TDI) and Structural Genomics Consortium (SGC) , University of Oxford , Old Road Campus, Roosevelt Drive , Oxford OX3 7DQ , U.K.; Institute for Pharmaceutical Chemistry, Buchmann Institute for Life Sciences Campus Riedbeerg , Goethe-University Frankfurt , 60438 Frankfurt am Main , Germany., Dye JM; US Army Medical Research Institute of Infectious Diseases , Viral Immunology Branch , Fort Detrick , Maryland 21702 , United States., Herdewijn P; Medicinal Chemistry, Rega Institute for Medical Research , KU Leuven , Herestraat 49-bus 1041 , 3000 Leuven , Belgium., Einav S; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, and Department of Microbiology and Immunology , Stanford University School of Medicine , Stanford , California 94305 , United States., De Jonghe S; Medicinal Chemistry, Rega Institute for Medical Research , KU Leuven , Herestraat 49-bus 1041 , 3000 Leuven , Belgium.

المصدر: Journal of medicinal chemistry [J Med Chem] 2019 Jun 27; Vol. 62 (12), pp. 5810-5831. Date of Electronic Publication: 2019 Jun 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*chemical synthesis , Antiviral Agents/*pharmacology , Protein Kinase Inhibitors/*chemical synthesis , Protein Kinase Inhibitors/*pharmacology , Protein Serine-Threonine Kinases/*antagonists & inhibitors , Pyridines/*chemical synthesis , Pyridines/*pharmacology, Antiviral Agents/chemistry ; Antiviral Agents/metabolism ; Cell Line ; Chemistry Techniques, Synthetic ; Humans ; Molecular Docking Simulation ; Protein Conformation ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/metabolism ; Protein Serine-Threonine Kinases/chemistry ; Protein Serine-Threonine Kinases/metabolism ; Pyridines/chemistry ; Pyridines/metabolism ; Structure-Activity Relationship

المؤلفون: Brannan JM; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Frederick, MD, 21702, USA., He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada., Howell KA; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA., Prugar LI; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Frederick, MD, 21702, USA., Zhu W; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada., Vu H; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA., Shulenin S; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA., Kailasan S; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA., Raina H; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA., Wong G; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada.; Department of Medical Microbiology, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada., Rahim MN; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada.; Department of Medical Microbiology, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada., Banadyga L; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada., Tierney K; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada., Zhao X; Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD, 21201, USA., Li Y; Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD, 21201, USA.; Institute for Bioscience and Biotechnology Research, University of Maryland, 9600 Gudelsky Drive, Rockville, MD, 20850, USA., Holtsberg FW; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA., Dye JM; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Frederick, MD, 21702, USA. john.m.dye1.civ@mail.mil., Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB, R3E 3R2, Canada. xiangguo.qiu@canada.ca.; Department of Medical Microbiology, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, MB, R3E 0J9, Canada. xiangguo.qiu@canada.ca., Aman MJ; Integrated BioTherapeutics, Inc., 4 Research Court, Suite 300, Rockville, MD, 20850, USA. javad@integratedbiotherapeutics.com.

المصدر: Nature communications [Nat Commun] 2019 Jan 10; Vol. 10 (1), pp. 105. Date of Electronic Publication: 2019 Jan 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*immunology , Antibodies, Neutralizing/*immunology , Ebolavirus/*immunology , Filoviridae Infections/*immunology , Marburgvirus/*immunology , Primate Diseases/*immunology, Animals ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Neutralizing/therapeutic use ; Ebolavirus/classification ; Ebolavirus/drug effects ; Ebolavirus/physiology ; Filoviridae Infections/therapy ; Filoviridae Infections/virology ; Host-Pathogen Interactions/drug effects ; Host-Pathogen Interactions/immunology ; Immunotherapy/methods ; Marburgvirus/drug effects ; Marburgvirus/physiology ; Primate Diseases/therapy ; Primate Diseases/virology ; Primates ; Treatment Outcome

المؤلفون: Coffin KM; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Liu J; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Warren TK; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Blancett CD; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Kuehl KA; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Nichols DK; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Bearss JJ; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Schellhase CW; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Retterer CJ; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Weidner JM; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Radoshitzky SR; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Brannan JM; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Cardile AP; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Dye JM; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Palacios G; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Sun MG; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Kuhn JH; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD 21702, USA., Bavari S; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA., Zeng X; United States Army Medical Research Institute of Infectious Diseases (USAMRIID), 1425 Porter Street, Fort Detrick, Frederick, MD 21702, USA. Electronic address: xiankun.zeng.fn@mail.mil.

المصدر: Cell host & microbe [Cell Host Microbe] 2018 Sep 12; Vol. 24 (3), pp. 405-416.e3. Date of Electronic Publication: 2018 Aug 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE

مواضيع طبية MeSH: Marburg Virus Disease/*virology , Marburgvirus/*physiology , Primate Diseases/*virology , Testis/*virology, Animals ; Macaca ; Male ; Marburg Virus Disease/immunology ; Marburg Virus Disease/metabolism ; Primate Diseases/immunology ; Primate Diseases/metabolism ; Sertoli Cells/metabolism ; Sertoli Cells/virology ; Survivors ; T-Lymphocytes, Regulatory/immunology ; Tight Junctions/metabolism ; Tight Junctions/virology