المؤلفون: Keith AD; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Sawyer EB; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Choy DCY; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Xie Y; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Biggs GS; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Klein OJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Brear PD; Department of Biochemistry, University of Cambridge, Sanger Building, Cambridge CB2 1GA, UK., Wales DJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk., Barker PD; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK. adk44@cam.ac.uk.

المصدر: Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2024 Jan 03; Vol. 26 (2), pp. 695-712. Date of Electronic Publication: 2024 Jan 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 100888160 Publication Model: Electronic Cited Medium: Internet ISSN: 1463-9084 (Electronic) Linking ISSN: 14639076 NLM ISO Abbreviation: Phys Chem Chem Phys Subsets: MEDLINE

مواضيع طبية MeSH: Hemeproteins*/metabolism, Anaerobiosis ; Phylogeny ; Heme/metabolism ; Escherichia coli/metabolism

المؤلفون: Iegre J; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Atkinson EL; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Brear PD; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., Cooper BM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk., Hyvönen M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., Spring DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. spring@ch.cam.ac.uk.

المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2021 May 26; Vol. 19 (20), pp. 4380-4396.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Casein Kinase II/*chemistry , Casein Kinase II/*metabolism , Molecular Probes/*metabolism, Animals ; Biocatalysis ; Drug Discovery ; Humans

المؤلفون: Atkinson EL; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Iegre J; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK., Brear PD; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Zhabina EA; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Hyvönen M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Spring DR; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 31; Vol. 26 (7). Date of Electronic Publication: 2021 Mar 31.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Casein Kinase II/*metabolism , Molecular Probes/*chemistry , Protein Kinase Inhibitors/*chemistry , Protein Kinases/*chemistry , Protein Kinases/*metabolism, Adenosine Triphosphate/metabolism ; Binding Sites ; COVID-19 ; Casein Kinase II/chemistry ; Dichlororibofuranosylbenzimidazole/chemistry ; Dichlororibofuranosylbenzimidazole/pharmacology ; Humans ; Molecular Probes/metabolism ; Naphthyridines/chemistry ; Naphthyridines/pharmacology ; Phenazines/chemistry ; Phenazines/pharmacology ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Protein Kinase Inhibitors/pharmacology

المؤلفون: Whitehouse AJ; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Libardo MDJ; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology , National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda , Maryland 20892 , United States., Kasbekar M; National Center for Advancing Translational Sciences , National Institutes of Health , Bethesda , Maryland 20850 , United States., Brear PD; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge , CB2 1GA , U.K., Fischer G; Department of Biochemistry , University of Cambridge , Tennis Court Road , Cambridge , CB2 1GA , U.K., Thomas CJ; National Center for Advancing Translational Sciences , National Institutes of Health , Bethesda , Maryland 20850 , United States., Barry CE 3rd; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology , National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda , Maryland 20892 , United States., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology , National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda , Maryland 20892 , United States., Coyne AG; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K., Abell C; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , U.K.

المصدر: Journal of medicinal chemistry [J Med Chem] 2019 Dec 12; Vol. 62 (23), pp. 10586-10604. Date of Electronic Publication: 2019 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*, Antitubercular Agents/*chemistry , Antitubercular Agents/*pharmacology , Fumarate Hydratase/*antagonists & inhibitors , Mycobacterium tuberculosis/*drug effects, Binding Sites ; Fumarate Hydratase/metabolism ; Humans ; Models, Molecular ; Molecular Structure ; Mycobacterium tuberculosis/enzymology ; Protein Conformation ; Structure-Activity Relationship