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المؤلفون: Nan Qiu, Chengsen Cui, Alexander Adibekian, Mingji Dai, Xianglin Yin, Jie-Qing Liu, Brendan G. Dwyer, Zhong-Jian Cai, Dominic Gregor Hoch, Daniel Abegg, Chang Liu
المصدر: J Am Chem Soc
مصطلحات موضوعية: Biological Products, DNA damage, Chemistry, Stereochemistry, Molecular Conformation, Nuclear Proteins, Total synthesis, Stereoisomerism, General Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, Chemical synthesis, Article, Catalysis, 0104 chemical sciences, chemistry.chemical_compound, Colloid and Surface Chemistry, Cascade reaction, Humans, Chemoproteomics, Diterpenes, Mode of action, DNA
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المؤلفون: Daniel Abegg, Dominic Gregor Hoch, Brendan G. Dwyer, Zhensheng Zhao, Dany Pechalrieu, Anton Shuster, Nan Qiu, Brittney Racioppo, Alexander Adibekian, Chao Wang
المصدر: Angewandte Chemie International Edition. 60:3071-3079
مصطلحات موضوعية: Proteases, Ultraviolet Rays, Drug Evaluation, Preclinical, 010402 general chemistry, Proteomics, Mycophenolate, 01 natural sciences, Catalysis, Carboxylesterase, Serine, Humans, Chemoproteomics, Sulfones, Enzyme Inhibitors, RNA, Small Interfering, 010405 organic chemistry, Drug discovery, Chemistry, Hydrolysis, Stereoisomerism, Serine hydrolase, General Medicine, General Chemistry, Urease, 0104 chemical sciences, Microscopy, Fluorescence, Pharmaceutical Preparations, Biochemistry, RNA Interference, Caco-2 Cells, Carboxylic Ester Hydrolases
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3
المؤلفون: Daniel Abegg, Chao Wang, Alexander Adibekian, Brendan G. Dwyer
المصدر: ChemBioChem. 20:2212-2216
مصطلحات موضوعية: Azides, Hydrolases, Organophosphonates, 010402 general chemistry, 01 natural sciences, Biochemistry, Serine, chemistry.chemical_compound, Humans, Serine hydrolase activity, Molecular Biology, 010405 organic chemistry, Chemistry, Drug discovery, Organic Chemistry, Leaving group, Activity-based proteomics, Serine hydrolase, 0104 chemical sciences, Molecular Probes, Click chemistry, Molecular Medicine, Click Chemistry, Azide
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المؤلفون: Romain Tessier, Stéphane Erb, Alexander Adibekian, Charlotte Sornay, Jerome Waser, Guilhem Chaubet, Daniel Abegg, Sarah Cianférani, Brendan G. Dwyer, Raj Kumar Nandi, Alain Wagner, Javier Ceballos
المصدر: Angewandte Chemie. 132
مصطلحات موضوعية: Bioconjugation, Biochemistry, Chemistry, General Medicine, Proteomics, In vitro, Cysteine
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5
المؤلفون: Romain Tessier, Raj Kumar Nandi, Brendan G. Dwyer, Daniel Abegg, Charlotte Sornay, Javier Ceballos, Stéphane Erb, Sarah Cianférani, Alain Wagner, Guilhem Chaubet, Alexander Adibekian, Jerome Waser
المصدر: Angewandte Chemie International Edition. 59
مصطلحات موضوعية: General Chemistry, Catalysis
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6
المصدر: Journal of Inorganic Biochemistry. 182:177-183
مصطلحات موضوعية: Indazole, Indazoles, 010405 organic chemistry, Stereochemistry, Oligonucleotide, RNA, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, Ruthenium, 0104 chemical sciences, Inorganic Chemistry, RNA, Transfer, Phe, chemistry.chemical_compound, chemistry, Transfer RNA, Organometallic Compounds, Ruthenium Compounds, NAMI-A, Dimethyl Sulfoxide, Ethidium bromide, DNA, Wybutosine
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المصدر: Cold Spring Harbor perspectives in biology. 10(11)
مصطلحات موضوعية: 0301 basic medicine, Drug discovery, Extramural, RNA, Computational biology, Biology, 010402 general chemistry, Highly selective, 01 natural sciences, Small molecule, General Biochemistry, Genetics and Molecular Biology, Article, 0104 chemical sciences, 03 medical and health sciences, RNA world hypothesis, 030104 developmental biology, Gene Expression Regulation, Drug Design, Animals, Humans, Self-Sustained Sequence Replication
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d74083258486d91ca3b855daba4447c
https://pubmed.ncbi.nlm.nih.gov/30385607 -
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المؤلفون: Dominic Gregor Hoch, Xiaojin Zhang, Howard Riezman, Dany Pechalrieu, Alexander Adibekian, J. Thomas Hannich, Chao Wang, Anton Shuster, Daniel Abegg, Qidong You, Brendan G. Dwyer
المصدر: Cell Chemical Biology, Vol. 27, No 5 (2020) pp. 586-597.e12
مصطلحات موضوعية: Proteomics, Xanthones, Clinical Biochemistry, Serine C-Palmitoyltransferase, Biology, 01 natural sciences, Biochemistry, Covalent inhibitors, Mice, chemistry.chemical_compound, Then test, Sphingosine, Drug Discovery, Animals, Humans, Chemoproteomics, Sphingosine-1-phosphate, Enzyme Inhibitors, Molecular Biology, Pharmacology, Mice, Inbred ICR, Sphingolipids, Natural product, 010405 organic chemistry, Gambogic acid, Serine C-palmitoyltransferase, Sphingolipid, 0104 chemical sciences, HEK293 Cells, chemistry, Covalent bond, ddc:540, Lipidomics, MCF-7 Cells, Molecular Medicine, lipids (amino acids, peptides, and proteins), Lysophospholipids
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d505c0608d7824d55064d62263d94728
https://doi.org/10.1016/j.chembiol.2020.03.008 -
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المؤلفون: Zi-Fu, Wang, Andrei, Ursu, Jessica L, Childs-Disney, Rea, Guertler, Wang-Yong, Yang, Viachaslau, Bernat, Suzanne G, Rzuczek, Rita, Fuerst, Yong-Jie, Zhang, Tania F, Gendron, Ilyas, Yildirim, Brendan G, Dwyer, Joseph E, Rice, Leonard, Petrucelli, Matthew D, Disney
المصدر: Cell chemical biology. 26(2)
مصطلحات موضوعية: Binding Sites, DNA Repeat Expansion, C9orf72 Protein, Amyotrophic Lateral Sclerosis, RNA-Binding Proteins, Molecular Dynamics Simulation, Article, Small Molecule Libraries, Kinetics, Frontotemporal Dementia, Polyribosomes, Protein Biosynthesis, Humans, Nucleic Acid Conformation, Thermodynamics, Nuclear Magnetic Resonance, Biomolecular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::db489aeede88b88763d3b52015dafa54
https://pubmed.ncbi.nlm.nih.gov/30503283 -
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المؤلفون: Daniel Abegg, Alexander Adibekian, Chao Wang, Brendan G. Dwyer
المصدر: ChemBioChem. 20:2161-2161
مصطلحات موضوعية: Serine, Drug discovery, Chemistry, Organic Chemistry, Feature discovery, Activity-based proteomics, Molecular Medicine, Cover (algebra), Computational biology, Molecular Biology, Biochemistry