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1دورية أكاديمية
المصدر: ADMET and DMPK, Vol 4, Iss 4, Pp 302-313 (2016)
مصطلحات موضوعية: ABC transporters, transport inhibition, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Justine Calise, Hannah DeBerg, Nahir Garabatos, Sugandhika Khosa, Veronique Bajzik, Lorena Botero Calderon, Kelly Aldridge, Mario Rosasco, Brian C. Ferslew, Tong Zhu, Ronald Smulders, Lisa M. Wheatley, Tanya M. Laidlaw, Tielin Qin, Gurunadh R. Chichili, Daniel C. Adelman, Mary Farrington, David Robinson, David Jeong, Stacie M. Jones, Srinath Sanda, David Larson, William W. Kwok, Carolyn Baloh, Gerald T. Nepom, Erik Wambre, Edwin H. Kim, Kari C. Nadeau, Anna Nowak-Wegrzyn, Robert A. Wood, Hugh A. Sampson, Amy M. Scurlock, Sharon Chinthrajah, Julie Wang, Robert D. Pesek, Sayantani B. Sindher, Mike Kulis, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Joy Laurienzo-Panza, null Rachel Yan, null Tielin Qin, Don Whitehouse, Michelle L. Sever, Marshall Plaut, A. Wesley Burks, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien-Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh-Anh Nguyen, Jessica Garber, Kimberly O’Brien, Brandon Larson, C. Cousens-Jacobs, Alex Hu
المصدر: Journal of Allergy and Clinical Immunology.
مصطلحات موضوعية: Immunology, Immunology and Allergy
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المؤلفون: V. Pierre, Kim L. R. Brouwer, C. K. Johnston, Daniel Gonzalez, Brian C. Ferslew
المصدر: CPT: Pharmacometrics & Systems Pharmacology. 6:331-339
مصطلحات موضوعية: medicine.medical_specialty, Population, Urine, Pharmacology, 030226 pharmacology & pharmacy, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Fibrosis, Internal medicine, Nonalcoholic fatty liver disease, medicine, Pharmacology (medical), education, Volume of distribution, education.field_of_study, business.industry, medicine.disease, 3. Good health, NONMEM, 030220 oncology & carcinogenesis, Modeling and Simulation, Morphine, business, medicine.drug
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المؤلفون: Kim L. R. Brouwer, Curtis K. Johnston, Brian C. Ferslew, Guoxiang Xie, Mingming Su, Wei Jia, Paul W. Stewart, A. Sidney Barritt
المصدر: Digestive Diseases and Sciences. 60:3318-3328
مصطلحات موضوعية: Adult, Male, Taurine, medicine.medical_specialty, Time Factors, Cirrhosis, Physiology, medicine.drug_class, digestive system, Gastroenterology, Article, Bile Acids and Salts, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, Tandem Mass Spectrometry, Internal medicine, Nonalcoholic fatty liver disease, medicine, Metabolome, Humans, Metabolomics, Least-Squares Analysis, Liver injury, Bile acid, business.industry, Discriminant Analysis, nutritional and metabolic diseases, Fasting, Middle Aged, Hepatology, Postprandial Period, medicine.disease, digestive system diseases, chemistry, Case-Control Studies, Female, Steatohepatitis, business, Biomarkers, Chromatography, Liquid
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المؤلفون: Brian C. Ferslew, Thomas J. Urban, Peter W. Swaan, Kathleen Köck, Kim L. R. Brouwer, Ida Netterberg, Paul W. Stewart, Kyunghee Yang
المصدر: Drug Metabolism and Disposition. 42:665-674
مصطلحات موضوعية: Drug, Drug-Related Side Effects and Adverse Reactions, medicine.drug_class, media_common.quotation_subject, Pharmaceutical Science, Pharmacology, Biology, Transfection, Cholestasis, Pharmacokinetics, Predictive Value of Tests, Risk Factors, medicine, Humans, Pharmaceutical sciences, Special Section on Transporters in Toxicity and Disease, ATP Binding Cassette Transporter, Subfamily B, Member 11, media_common, Liver injury, Bile acid, medicine.disease, Bile Salt Export Pump, HEK293 Cells, Logistic Models, Liver, Pharmaceutical Preparations, ATP-Binding Cassette Transporters, Chemical and Drug Induced Liver Injury, Multidrug Resistance-Associated Proteins
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70303feaa3eec17d2cde5d8d9bf9a05d
https://doi.org/10.1124/dmd.113.054304 -
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المؤلفون: Kim L. R. Brouwer, Nathan D. Pfeifer, Brian C. Ferslew, Rhiannon N. Hardwick, Arlene S. Bridges
المصدر: Journal of Pharmacology and Experimental Therapeutics. 347:737-745
مصطلحات موضوعية: Male, medicine.medical_specialty, Abcg2, Metabolism, Transport, and Pharmacogenomics, Excretion, Tandem Mass Spectrometry, Internal medicine, medicine, Animals, Bile, Rosuvastatin, Rosuvastatin Calcium, Biliary Tract, Pentanoic Acids, Cells, Cultured, Chromatography, High Pressure Liquid, Mice, Knockout, Pharmacology, Sulfonamides, biology, Multidrug resistance-associated protein 2, Rats, Fluorobenzenes, Pyrimidines, Endocrinology, Liver, Hepatocytes, biology.protein, Molecular Medicine, ATP-Binding Cassette Transporters, Efflux, Hepatic Elimination, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Carrier Proteins, Perfusion, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1556061840e38a2a0fbda8a1bfa4ad
https://doi.org/10.1124/jpet.113.208314 -
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المؤلفون: Michael A. Wells, Fred B. Lih, Laura M. DeGraff, Bobbie K.H. Nguyen, Weibin Zha, Craig R. Lee, Darryl C. Zeldin, Rachel J. Church, Kim L. R. Brouwer, Matthew L. Edin, A. Sidney Barritt, Kimberly C. Vendrov, Brian C. Ferslew
مصطلحات موضوعية: 0301 basic medicine, Epoxide hydrolase 2, Adult, Male, medicine.medical_specialty, Physiology, Adipose tissue, Inflammation, Biochemistry, digestive system, Cytochrome P-450 CYP2J2, Article, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, Mice, 8,11,14-Eicosatrienoic Acid, Cytochrome P-450 Enzyme System, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Animals, Humans, Pharmacology, Epoxide Hydrolases, Metabolic Syndrome, biology, Hydrolysis, Cytochrome P450, nutritional and metabolic diseases, Cell Biology, Middle Aged, medicine.disease, digestive system diseases, Diet, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, Liver, Solubility, biology.protein, Disease Progression, Arachidonic acid, Female, medicine.symptom, Steatosis, Steatohepatitis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc424fd3cd910368d65779df240fd4d3
https://europepmc.org/articles/PMC5035202/ -
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المؤلفون: Changxiao Liu, Kim L. R. Brouwer, Brian C. Ferslew, Mingming Su, Cynthia Rajani, Wei Jia, Ke Lan, Guoxiang Xie
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, education, Cometabolism, Stereoisomerism, 01 natural sciences, Medicinal chemistry, Article, Mass Spectrometry, Dissociation (chemistry), Analytical Chemistry, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, Fragmentation (mass spectrometry), Humans, Dehydrogenation, Molecular Structure, 010401 analytical chemistry, Deoxycholic acid, Cholic acid, 0104 chemical sciences, 030104 developmental biology, chemistry, Biochemistry, Alcohols, Female, Carbon monoxide
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349b7b1cfe1c96348a2195c68e2af9ac
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المؤلفون: Kim L. R. Brouwer, Kathleen Köck, Brian C. Ferslew
المصدر: Drug Transporters
مصطلحات موضوعية: Chemistry, Liver structure, Pharmacology, Drug metabolism, Drug transport
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::331563c7586873018050508376b6e618
https://doi.org/10.1002/9781118705308.ch13 -
10Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis
المؤلفون: Paul W. Stewart, E. Tsakalozou, Kim L. R. Brouwer, C. K. Johnston, Mary F. Paine, Wei Jia, Arlene S. Bridges, Brian C. Ferslew, A. S. Barritt
المصدر: Clinical pharmacology and therapeutics. 97(4)
مصطلحات موضوعية: Adult, Liver Cirrhosis, Male, medicine.medical_specialty, medicine.drug_class, Cmax, digestive system, Article, Bile Acids and Salts, Cohort Studies, Insulin resistance, Pharmacokinetics, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Humans, Pharmacology (medical), Pharmacology, Morphine Derivatives, Bile acid, Chemistry, Middle Aged, medicine.disease, Analgesics, Opioid, Endocrinology, Biochemistry, Liver, Area Under Curve, Toxicity, Morphine, Female, Efflux, Insulin Resistance, Glucuronide, medicine.drug