المؤلفون: Rhiannon N. Hardwick, Marina Snellings, Brian C. Ferslew, Yang Lu, Kim L.R. Browuer

المصدر: ADMET and DMPK, Vol 4, Iss 4, Pp 302-313 (2016)

مصطلحات موضوعية: ABC transporters, transport inhibition, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://pub.iapchem.org/ojs/index.php/admet/article/view/322; https://doaj.org/toc/1848-7718

URL الوصول: https://doaj.org/article/51a8a10f0f3b47b196b087d93fcf53be

المؤلفون: Justine Calise, Hannah DeBerg, Nahir Garabatos, Sugandhika Khosa, Veronique Bajzik, Lorena Botero Calderon, Kelly Aldridge, Mario Rosasco, Brian C. Ferslew, Tong Zhu, Ronald Smulders, Lisa M. Wheatley, Tanya M. Laidlaw, Tielin Qin, Gurunadh R. Chichili, Daniel C. Adelman, Mary Farrington, David Robinson, David Jeong, Stacie M. Jones, Srinath Sanda, David Larson, William W. Kwok, Carolyn Baloh, Gerald T. Nepom, Erik Wambre, Edwin H. Kim, Kari C. Nadeau, Anna Nowak-Wegrzyn, Robert A. Wood, Hugh A. Sampson, Amy M. Scurlock, Sharon Chinthrajah, Julie Wang, Robert D. Pesek, Sayantani B. Sindher, Mike Kulis, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Joy Laurienzo-Panza, null Rachel Yan, null Tielin Qin, Don Whitehouse, Michelle L. Sever, Marshall Plaut, A. Wesley Burks, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien-Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh-Anh Nguyen, Jessica Garber, Kimberly O’Brien, Brandon Larson, C. Cousens-Jacobs, Alex Hu

المصدر: Journal of Allergy and Clinical Immunology.

مصطلحات موضوعية: Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::91c8110d6047e5910fc8bb0d5231f943
https://doi.org/10.1016/j.jaci.2023.03.020

المؤلفون: V. Pierre, Kim L. R. Brouwer, C. K. Johnston, Daniel Gonzalez, Brian C. Ferslew

المصدر: CPT: Pharmacometrics & Systems Pharmacology. 6:331-339

مصطلحات موضوعية: medicine.medical_specialty, Population, Urine, Pharmacology, 030226 pharmacology & pharmacy, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Fibrosis, Internal medicine, Nonalcoholic fatty liver disease, medicine, Pharmacology (medical), education, Volume of distribution, education.field_of_study, business.industry, medicine.disease, 3. Good health, NONMEM, 030220 oncology & carcinogenesis, Modeling and Simulation, Morphine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d48a43a82895f445fd79f36e49232c3a
https://doi.org/10.1002/psp4.12185

المؤلفون: Kim L. R. Brouwer, Curtis K. Johnston, Brian C. Ferslew, Guoxiang Xie, Mingming Su, Wei Jia, Paul W. Stewart, A. Sidney Barritt

المصدر: Digestive Diseases and Sciences. 60:3318-3328

مصطلحات موضوعية: Adult, Male, Taurine, medicine.medical_specialty, Time Factors, Cirrhosis, Physiology, medicine.drug_class, digestive system, Gastroenterology, Article, Bile Acids and Salts, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, Tandem Mass Spectrometry, Internal medicine, Nonalcoholic fatty liver disease, medicine, Metabolome, Humans, Metabolomics, Least-Squares Analysis, Liver injury, Bile acid, business.industry, Discriminant Analysis, nutritional and metabolic diseases, Fasting, Middle Aged, Hepatology, Postprandial Period, medicine.disease, digestive system diseases, chemistry, Case-Control Studies, Female, Steatohepatitis, business, Biomarkers, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416c6d903d054427bc567c312f7568d4
https://doi.org/10.1007/s10620-015-3776-8

المؤلفون: Brian C. Ferslew, Thomas J. Urban, Peter W. Swaan, Kathleen Köck, Kim L. R. Brouwer, Ida Netterberg, Paul W. Stewart, Kyunghee Yang

المصدر: Drug Metabolism and Disposition. 42:665-674

مصطلحات موضوعية: Drug, Drug-Related Side Effects and Adverse Reactions, medicine.drug_class, media_common.quotation_subject, Pharmaceutical Science, Pharmacology, Biology, Transfection, Cholestasis, Pharmacokinetics, Predictive Value of Tests, Risk Factors, medicine, Humans, Pharmaceutical sciences, Special Section on Transporters in Toxicity and Disease, ATP Binding Cassette Transporter, Subfamily B, Member 11, media_common, Liver injury, Bile acid, medicine.disease, Bile Salt Export Pump, HEK293 Cells, Logistic Models, Liver, Pharmaceutical Preparations, ATP-Binding Cassette Transporters, Chemical and Drug Induced Liver Injury, Multidrug Resistance-Associated Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70303feaa3eec17d2cde5d8d9bf9a05d
https://doi.org/10.1124/dmd.113.054304

المؤلفون: Kim L. R. Brouwer, Nathan D. Pfeifer, Brian C. Ferslew, Rhiannon N. Hardwick, Arlene S. Bridges

المصدر: Journal of Pharmacology and Experimental Therapeutics. 347:737-745

مصطلحات موضوعية: Male, medicine.medical_specialty, Abcg2, Metabolism, Transport, and Pharmacogenomics, Excretion, Tandem Mass Spectrometry, Internal medicine, medicine, Animals, Bile, Rosuvastatin, Rosuvastatin Calcium, Biliary Tract, Pentanoic Acids, Cells, Cultured, Chromatography, High Pressure Liquid, Mice, Knockout, Pharmacology, Sulfonamides, biology, Multidrug resistance-associated protein 2, Rats, Fluorobenzenes, Pyrimidines, Endocrinology, Liver, Hepatocytes, biology.protein, Molecular Medicine, ATP-Binding Cassette Transporters, Efflux, Hepatic Elimination, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Carrier Proteins, Perfusion, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1556061840e38a2a0fbda8a1bfa4ad
https://doi.org/10.1124/jpet.113.208314

المؤلفون: Michael A. Wells, Fred B. Lih, Laura M. DeGraff, Bobbie K.H. Nguyen, Weibin Zha, Craig R. Lee, Darryl C. Zeldin, Rachel J. Church, Kim L. R. Brouwer, Matthew L. Edin, A. Sidney Barritt, Kimberly C. Vendrov, Brian C. Ferslew

مصطلحات موضوعية: 0301 basic medicine, Epoxide hydrolase 2, Adult, Male, medicine.medical_specialty, Physiology, Adipose tissue, Inflammation, Biochemistry, digestive system, Cytochrome P-450 CYP2J2, Article, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, Mice, 8,11,14-Eicosatrienoic Acid, Cytochrome P-450 Enzyme System, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Animals, Humans, Pharmacology, Epoxide Hydrolases, Metabolic Syndrome, biology, Hydrolysis, Cytochrome P450, nutritional and metabolic diseases, Cell Biology, Middle Aged, medicine.disease, digestive system diseases, Diet, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, chemistry, Liver, Solubility, biology.protein, Disease Progression, Arachidonic acid, Female, medicine.symptom, Steatosis, Steatohepatitis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc424fd3cd910368d65779df240fd4d3
https://europepmc.org/articles/PMC5035202/

المؤلفون: Changxiao Liu, Kim L. R. Brouwer, Brian C. Ferslew, Mingming Su, Cynthia Rajani, Wei Jia, Ke Lan, Guoxiang Xie

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, education, Cometabolism, Stereoisomerism, 01 natural sciences, Medicinal chemistry, Article, Mass Spectrometry, Dissociation (chemistry), Analytical Chemistry, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, Fragmentation (mass spectrometry), Humans, Dehydrogenation, Molecular Structure, 010401 analytical chemistry, Deoxycholic acid, Cholic acid, 0104 chemical sciences, 030104 developmental biology, chemistry, Biochemistry, Alcohols, Female, Carbon monoxide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349b7b1cfe1c96348a2195c68e2af9ac

المؤلفون: Kim L. R. Brouwer, Kathleen Köck, Brian C. Ferslew

المصدر: Drug Transporters

مصطلحات موضوعية: Chemistry, Liver structure, Pharmacology, Drug metabolism, Drug transport

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::331563c7586873018050508376b6e618
https://doi.org/10.1002/9781118705308.ch13

المؤلفون: Paul W. Stewart, E. Tsakalozou, Kim L. R. Brouwer, C. K. Johnston, Mary F. Paine, Wei Jia, Arlene S. Bridges, Brian C. Ferslew, A. S. Barritt

المصدر: Clinical pharmacology and therapeutics. 97(4)

مصطلحات موضوعية: Adult, Liver Cirrhosis, Male, medicine.medical_specialty, medicine.drug_class, Cmax, digestive system, Article, Bile Acids and Salts, Cohort Studies, Insulin resistance, Pharmacokinetics, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Humans, Pharmacology (medical), Pharmacology, Morphine Derivatives, Bile acid, Chemistry, Middle Aged, medicine.disease, Analgesics, Opioid, Endocrinology, Biochemistry, Liver, Area Under Curve, Toxicity, Morphine, Female, Efflux, Insulin Resistance, Glucuronide, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddf69bdc95ade788e6d487aa33fe61a
https://pubmed.ncbi.nlm.nih.gov/25669174