المؤلفون: Steven J Kleene, Brian J Siroky, Julio A Landero-Figueroa, Bradley P Dixon, Nolan W Pachciarz, Lu Lu, Nancy K Kleene

المصدر: PLoS ONE, Vol 14, Iss 3, p e0214053 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/be21d27a5729441384f21ae60bb2e47f

المؤلفون: Bradley P Dixon, Jeff Henry, Brian J Siroky, Albert Chu, Pamela A Groen, John J Bissler

المصدر: PLoS ONE, Vol 6, Iss 1, p e16595 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3030598?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/464cdffd248c45b7bfedf7ec0aa5d4ba

المؤلفون: Xiaolei Liu, Elizabeth J. Kopras, Yang Liu, Chenggang Li, Anya Alayev, David R. Plas, Erik Zhang, Kantha Medepalli, Kouhei Masuda, Brian J. Siroky, David J. Kwiatkowski, Yang Sun, Marina K. Holz, Julia Sun, David Neal Franz, Michael T. Borchers, Darcy A. Krueger, Jamie K. Capal, Kathryn A. Wikenheiser-Brokamp, Jane J. Yu, Andrew R. Osterburg, Na Li, Maxwell Mays

المصدر: Molecular Cancer Research. 15:1318-1330

مصطلحات موضوعية: Male, 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Lung Neoplasms, Cell Survival, Angiomyolipoma, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Mice, 03 medical and health sciences, Tuberous sclerosis, Downregulation and upregulation, Cell Line, Tumor, Tuberous Sclerosis Complex 2 Protein, medicine, Animals, Humans, Lymphangioleiomyomatosis, Child, Prostaglandin receptor, Receptor, Molecular Biology, Sulfonamides, Epilepsy, Tumor Suppressor Proteins, Brain, Infant, medicine.disease, Kidney Neoplasms, Up-Regulation, nervous system diseases, 030104 developmental biology, medicine.anatomical_structure, Oncology, Child, Preschool, Mutation, Receptors, Prostaglandin E, EP3 Subtype, biology.protein, Cancer research, Female, Ras Homolog Enriched in Brain Protein, lipids (amino acids, peptides, and proteins), TSC1, TSC2, RHEB

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c46b81a990633960c5b18a7060006b
https://doi.org/10.1158/1541-7786.mcr-17-0077

المؤلفون: Keri Anne Drake, Prasad Devarajan, Brian J. Siroky, Kritton Shay-Winkler, Priyanka Parameswaran, LaTawnya Pleasant, Qing Ma, Jeffrey Robbins, Mahima Devarajan

المصدر: American Journal of Physiology-Renal Physiology. 313:F699-F705

مصطلحات موضوعية: medicine.medical_specialty, Pathology, Time Factors, Physiology, 030232 urology & nephrology, Cardiomyopathy, Mice, Transgenic, Cardiorenal syndrome, 030204 cardiovascular system & hematology, Kidney, 03 medical and health sciences, 0302 clinical medicine, Lipocalin-2, Internal medicine, Renin, Renin–angiotensin system, medicine, Animals, Genetic Predisposition to Disease, Heart Failure, Cardio-Renal Syndrome, business.industry, Acute kidney injury, alpha-Crystallin B Chain, Acute Kidney Injury, medicine.disease, Up-Regulation, Neutrophil gelatinase-associated lipocalin, Disease Models, Animal, Phenotype, medicine.anatomical_structure, Creatinine, Reperfusion Injury, Heart failure, Asymptomatic Diseases, Mutation, Disease Progression, Cardiology, Cardiomyopathies, business, Biomarkers, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a446478b2fa6ef0d2dd83e6739f027
https://doi.org/10.1152/ajprenal.00505.2016

المؤلفون: Jialiu Liu, Nancy K. Kleene, Nolan W. Pachciarz, Raven G. Comer, Steven J. Kleene, Bradley P. Dixon, Lu Lu, Brian J. Siroky, John J. Bissler, Charles D. Varnell

المصدر: American Journal of Physiology-Renal Physiology. 312:F791-F805

مصطلحات موضوعية: 0301 basic medicine, TRPV4, GABA Plasma Membrane Transport Proteins, medicine.medical_specialty, Physiology, TRPM Cation Channels, TRPV Cation Channels, Mice, Transgenic, Biology, Transfection, Cell Line, Osmotic stress response, Mice, 03 medical and health sciences, Transient receptor potential channel, Osmoregulation, 0302 clinical medicine, Osmotic Pressure, Internal medicine, Sense (molecular biology), medicine, Animals, TRPM3, Cilia, Kidney Tubules, Collecting, Osmotic response, Gene Editing, Saline Solution, Hypertonic, Cilium, Epithelial Cells, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Hydroxyprostaglandin Dehydrogenases, CRISPR-Cas Systems, 030217 neurology & neurosurgery, Research Article, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d209a4358d147bba20a872f74677a948
https://doi.org/10.1152/ajprenal.00465.2015

المؤلفون: Charilaos Filippakis, Amine Belaid, Brian J. Siroky, Julie Nijmeh, Thomas Alesi, Nicola Alesi, Ellizabeth Henske, Constance Wu, Hilaire C. Lam

المصدر: Molecular Cancer Research. 18:A01-A01

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Endosome, Chemistry, Autophagy, mTORC1, medicine.disease_cause, Glutamine, Oncology, Downregulation and upregulation, Cancer research, medicine, TSC2, Carcinogenesis, Molecular Biology, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::10aa98001edd13e0bb8e292c040e3610
https://doi.org/10.1158/1557-3125.pi3k-mtor18-a01

المؤلفون: Hilaire C. Lam, Elizabeth P. Henske, Brian J. Siroky

المصدر: Nature reviews. Nephrology. 14(11)

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Angiomyolipoma, mTORC1, In Vitro Techniques, Mechanistic Target of Rapamycin Complex 1, Tuberous Sclerosis Complex 1 Protein, 03 medical and health sciences, Tuberous sclerosis, Renal cell carcinoma, Stress, Physiological, Tuberous Sclerosis, Tuberous Sclerosis Complex 2 Protein, medicine, Autophagy, Tumor Microenvironment, Animals, Humans, Carcinoma, Renal Cell, Kidney, business.industry, Autosomal dominant trait, Kidney Diseases, Cystic, medicine.disease, Lipid Metabolism, Kidney Neoplasms, nervous system diseases, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Nephrology, Cancer research, TSC1, TSC2, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab11b62a0735fdcf8d082f695a17671
https://pubmed.ncbi.nlm.nih.gov/30232410

المؤلفون: Nicola Alesi, Brian J. Siroky, Hilaire C. Lam, Thomas Hougard, Harilaos Filippakis, Amine Belaid, Constance Wu, Julie Nijmeh, Elizabeth P. Henske

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Carcinogenesis, Science, TSC2-deficient Cells, Down-Regulation, mTORC1, Mice, SCID, medicine.disease_cause, Autophagy-Related Protein 5, Cell Line, Amiloride, 03 medical and health sciences, chemistry.chemical_compound, Mice, Downregulation and upregulation, Mice, Inbred NOD, Tuberous Sclerosis, Ethylisopropylamiloride (EIPA), Tuberous Sclerosis Complex 2 Protein, medicine, Autophagy, Animals, Protein Kinase Inhibitors, Cell Proliferation, Dextran Uptake, Multidisciplinary, Chemistry, Lipid metabolism, Dextrans, Class III Phosphatidylinositol 3-Kinases, Mouse Embryonic Fibroblasts (MEFs), nervous system diseases, Up-Regulation, 030104 developmental biology, Cell culture, Tuberous Sclerosis Complex, Cancer research, Medicine, Pinocytosis, TSC2, Growth inhibition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e46e67889644692827a4a0a1edd5f6
https://pubmed.ncbi.nlm.nih.gov/30242175

المؤلفون: Prasad Devarajan, Emily Donaworth, Brian J. Siroky, Rajit K. Basu, Hector R. Wong

المصدر: Renal Failure. 37:469-475

مصطلحات موضوعية: medicine.medical_specialty, Time Factors, Urology, Renal function, Apoptosis, Kidney, Kidney Function Tests, urologic and male genital diseases, Critical Care and Intensive Care Medicine, Article, Sepsis, Mice, chemistry.chemical_compound, medicine, Animals, Renal Insufficiency, Inflammation, Creatinine, Renal ischemia, urogenital system, business.industry, Acute kidney injury, Recovery of Function, General Medicine, Acute Kidney Injury, medicine.disease, female genital diseases and pregnancy complications, Surgery, Disease Models, Animal, Matrix Metalloproteinase 8, medicine.anatomical_structure, chemistry, Nephrology, Reperfusion Injury, business, Reperfusion injury, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9816b345534341f8544481ef8bb26056
https://doi.org/10.3109/0886022x.2014.996842

المؤلفون: Karen Agricola, Cynthia Tudor, Jamie K. Capal, Hannah Schäfer, Brian J. Siroky, David Neal Franz, Darcy A. Krueger, Anna R. Thamann, Bradley P. Dixon, Andrew T. Trout, Alexander J. Towbin

المصدر: The Journal of pediatrics. 187

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, medicine.medical_specialty, Adolescent, Autosomal dominant polycystic kidney disease, Kidney, Contiguous gene syndrome, 03 medical and health sciences, Tuberous sclerosis, Young Adult, 0302 clinical medicine, Tuberous Sclerosis, medicine, Humans, Clinical significance, Cyst, 030212 general & internal medicine, Child, Sirolimus, Renal cystic disease, Subependymal giant cell astrocytoma, business.industry, fungi, food and beverages, Infant, Kidney Diseases, Cystic, medicine.disease, Magnetic Resonance Imaging, Tuberous sclerosis protein, 030104 developmental biology, Treatment Outcome, Child, Preschool, Pediatrics, Perinatology and Child Health, Female, business, Immunosuppressive Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304f4c13f314eaae1772943fb94e3386
https://pubmed.ncbi.nlm.nih.gov/28600153