يعرض 1 - 4 نتائج من 4 نتيجة بحث عن '"Brian Jermain"', وقت الاستعلام: 0.92s تنقيح النتائج
  1. 1
    دورية أكاديمية
    A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

    المؤلفون: Patrick O. Hanafin, Brian Jermain, Anthony J. Hickey, Alexander V. Kabanov, Angela DM. Kashuba, Timothy P. Sheahan, Gauri G. Rao

    المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 2, Pp 89-99 (2021)

    مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2163-8306

    URL الوصول: https://doaj.org/article/bda925b05d3b4d6ab7b8cfb0cdce9b1b

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  2. 2
    A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

    المؤلفون: Anthony J. Hickey, Angela D. M. Kashuba, Alexander V. Kabanov, Timothy P. Sheahan, Patrick O. Hanafin, Gauri G. Rao, Brian Jermain

    المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 2, Pp 89-99 (2021)
    CPT: Pharmacometrics & Systems Pharmacology

    مصطلحات موضوعية: viruses, Respiratory Mucosa, Pharmacology, Antiviral Agents, Loading dose, Article, Mice, chemistry.chemical_compound, Species Specificity, Pharmacokinetics, In vivo, Modelling and Simulation, Animals, Humans, Distribution (pharmacology), Pharmacology (medical), Cells, Cultured, Active metabolite, Mice, Knockout, Alanine, Research, lcsh:RM1-950, COVID-19, Articles, Prodrug, Adenosine Monophosphate, COVID-19 Drug Treatment, Mice, Inbred C57BL, lcsh:Therapeutics. Pharmacology, chemistry, Modeling and Simulation, Models, Animal, Nucleoside triphosphate, Female, Nucleoside

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa200f34fe43222110ae0968f6598f6
    https://doaj.org/article/bda925b05d3b4d6ab7b8cfb0cdce9b1b

    View record at Wiley Find this article in full text from ProQuest
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  3. 3
    Pharmacodynamic and immunomodulatory effects of polymyxin B in combination with fosfomycin against KPC-2-producing Klebsiella pneumoniae

    المؤلفون: Rajnikant Sharma, Estefany Garcia, John K. Diep, Vince H. Lee, Faisal Minhaj, Brian Jermain, Evelyn J. Ellis-Grosse, Cely S. Abboud, Gauri G. Rao

    المصدر: International journal of antimicrobial agents. 59(4)

    مصطلحات موضوعية: Microbiology (medical), Immunity, General Medicine, Microbial Sensitivity Tests, beta-Lactamases, Anti-Bacterial Agents, Klebsiella Infections, Klebsiella pneumoniae, Infectious Diseases, Carbapenem-Resistant Enterobacteriaceae, Bacterial Proteins, Fosfomycin, Humans, Pharmacology (medical), Polymyxin B

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d49a73ba93e7913c7b44494b12e86d
    https://pubmed.ncbi.nlm.nih.gov/35288260

    View record from ScienceDirect Full Text via ClinicalKey
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  4. 4
    Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing

    المؤلفون: Yanguang Cao, Gauri G. Rao, Brian Jermain, Adrian Luis Lifschitz, Carlos Edmundo Lanusse, Patrick O. Hanafin

    المصدر: CONICET Digital (CONICET)
    Consejo Nacional de Investigaciones Científicas y Técnicas
    instacron:CONICET
    Journal of Pharmaceutical Sciences

    مصطلحات موضوعية: PHARMACOKINETICS, animal diseases, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, 0302 clinical medicine, Ivermectin, Oral administration, Importins, Receptor, Lung, education.field_of_study, Chemistry, Physiologically based pharmacokinetic modeling, 021001 nanoscience & nanotechnology, Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism, Drug repositioning, medicine.anatomical_structure, purl.org/becyt/ford/3 [https], Coronavirus Infections, 0210 nano-technology, IMPORTINS, medicine.drug, Pneumonia, Viral, Population, SARS-COV-2, Antiviral Agents, Models, Biological, Betacoronavirus, 03 medical and health sciences, purl.org/becyt/ford/3.3 [https], Pharmacokinetic/pharmacodynamic (PK/PD) modeling, Pharmacometrics, Pharmacokinetics, PHARMACOKINETIC/PHARMACODYNAMIC (PK/PD) MODELING, parasitic diseases, PHARMACOMETRICS, medicine, Animals, Humans, Computer Simulation, MINIMAL PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL, education, Pandemics, IC50, KINETICS, SARS-CoV-2, Drug Repositioning, COVID-19, Kinetics, PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING, Minimal physiologically-based pharmacokinetic model, Cattle, IVERMECTIN

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8545152e2d1b9fb02e826aae040905a0
    https://jpharmsci.org/article/S0022-3549(20)30495-0/fulltext

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