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1
المؤلفون: Brian M. Arnold, Miriam del Prado, Smriti Iyengar, Edward L. Mattiuz, Zhipei Wu, Mark A. Winter, David Bleakman, Ken H. Ho, Ann Marie L. Ogden, Paul L. Ornstein, Carrie K. Jones, Sandra Ann Filla, Brian Michael Mathes, Michael Gregory Bell, Douglas Richard Stack, Ana Maria Escribano, Thomas J. Bleisch, Ana I. Mateo, Kevin John Hudziak, Andrew Alt, Rosa Maria A. Simmons, Harlan E. Shannon, Robert E. Stratford, Jose A. Martinez-Perez, Esteban Dominguez, Ana M. Castaño
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:6459-6462
مصطلحات موضوعية: Molecular Sequence Data, Clinical Biochemistry, Administration, Oral, Pain, Pharmaceutical Science, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Receptors, Kainic Acid, Oral administration, In vivo, Drug Discovery, Animals, Prodrugs, Amino Acid Sequence, Molecular Biology, Benzoic acid, chemistry.chemical_classification, Chemistry, Organic Chemistry, Haplorhini, Prodrug, Isoquinolines, Amino acid, Disease Models, Animal, Molecular Medicine
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2
المؤلفون: Edward L. Mattiuz, Ann Marie L. Ogden, Ana M. Castaño, Zhipei Wu, Robert E. Stratford, E. Dominguez, Thomas J. Bleisch, Brian Michael Mathes, Brian M. Arnold, David Bleakman, Smriti Iyengar, Rosa Maria A. Simmons, Harlan E. Shannon, Sandra Ann Filla, Jose A. Martinez-Perez, Douglas Richard Stack, Ana I. Mateo, Miriam del Prado, Kevin John Hudziak, Andrew Alt, Michael Gregory Bell, Carrie K. Jones, Paul L. Ornstein, Jennifer L. Buckmaster, Ana Maria Escribano, Mark A. Winter, Ken H. Ho
المصدر: Journal of Medicinal Chemistry. 48:4200-4203
مصطلحات موضوعية: Analgesic, Biological Availability, Pain, Kainate receptor, Pharmacology, Cell Line, Receptors, Kainic Acid, Drug Discovery, Animals, Humans, Receptors, AMPA, Amino Acids, Receptor, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, chemistry.chemical_classification, Analgesics, Chemistry, Glutamate receptor, Antagonist, Prodrug, Recombinant Proteins, Rats, Amino acid, Disease Models, Animal, Spinal Cord, Biochemistry, Hyperalgesia, Molecular Medicine, Licking
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3
المؤلفون: Stephen D. Silberstein, Brian M. Arnold, Lee A. Phebus, F Vandenhende, Kirk W. Johnson, Frederick G. Freitag, RG Wallihan, Stewart J. Tepper, David Bleakman, Timothy R. Smith, Christine N. Sang, NM Ramadan, Paul L. Ornstein, Amy S. Chappell
المصدر: Cephalalgia. 24:596-602
مصطلحات موضوعية: Adult, Male, medicine.drug_class, Migraine Disorders, Tetrazoles, Placebo, law.invention, 03 medical and health sciences, 0302 clinical medicine, Receptors, Kainic Acid, Randomized controlled trial, law, medicine, Humans, Receptors, AMPA, Adverse effect, Analysis of Variance, Chi-Square Distribution, business.industry, Antagonist, 030206 dentistry, General Medicine, Middle Aged, Isoquinolines, Receptor antagonist, medicine.disease, Clinical trial, Sumatriptan, Migraine, Anesthesia, Acute Disease, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, medicine.drug
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4
المؤلفون: Miriam del Prado, Ken H. Ho, Brian Michael Mathes, Smriti Iyengar, Mark A. Winter, Harlan E. Shannon, Carrie K. Jones, David K. Clawson, Ana Maria Escribano, Douglas Richard Stack, Esteban Dominguez, Paul L. Ornstein, Ana I. Mateo, Jose A. Martinez-Perez, Kevin John Hudziak, Andrew Alt, Edward L. Mattiuz, Brian M. Arnold, Sandra Ann Filla, Thomas J. Bleisch, Ana M. Castaño, Michael Gregory Bell, Rosa Maria A. Simmons, Robert E. Stratford, Ann Marie L. Ogden, Zhipei Wu, David Bleakman
المصدر: Bioorganicmedicinal chemistry letters. 23(23)
مصطلحات موضوعية: Male, Stereochemistry, Clinical Biochemistry, Analgesic, Molecular Sequence Data, Pharmaceutical Science, Administration, Oral, Pain, Tetrazoles, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Receptors, Kainic Acid, In vivo, Drug Discovery, Animals, Tetrazole, Prodrugs, Amino Acid Sequence, Receptor, Molecular Biology, Organic Chemistry, Prodrug, Isoquinolines, In vitro, Rats, Disease Models, Animal, chemistry, Molecular Medicine, Selectivity, Linker