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المؤلفون: Bei Zhang, Jiayi Xu, Robert W. Myers, Roman Kats-Kagan, Qinghong Fu, Sunita Malkani, Hsuan-shen Chen, Rui Zhang, Maria E. Trujillo, Michael Kavana, Daniel R. McMasters, Brian T. Campbell, George H. Addona, George J. Eiermann, Zhesheng Chen, Michele Pachanski, Fengqi Zhang, Brian T. Farrer, Kaushik Mitra, Libo Xu, Nadine Elowe, Joel P. Berger, Emma R. Parmee, Songnian Lin, Wen Feng, Xinchun Tong
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:2069-2073
مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, medicine.medical_specialty, Indoles, medicine.medical_treatment, Clinical Biochemistry, Enzyme Activators, Pharmaceutical Science, 01 natural sciences, Biochemistry, Mice, 03 medical and health sciences, chemistry.chemical_compound, Enzyme activator, Allosteric Regulation, Diabetes mellitus, Internal medicine, Glucokinase, Drug Discovery, medicine, Animals, Humans, Hypoglycemic Agents, Insulin, Glucose homeostasis, Molecular Biology, Hexokinase, Chemistry, Organic Chemistry, Type 2 Diabetes Mellitus, Metabolism, medicine.disease, 0104 chemical sciences, Enzyme Activation, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Drug Design, Molecular Medicine
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المؤلفون: Wen Feng, Bei Zhang, Songnian Lin, Sunita Malkani, Hsuan-shen Chen, Libo Xu, Jiayi Xu, Rui Zhang, Nadine Elowe, Qinghong Fu, Maria E. Trujillo, Zhesheng Chen, Brian T. Farrer, Robert W. Myers, Michele Pachanski, Michael Kavana, George H. Addona, Daniel R. McMasters, George J. Eiermann, Xinchun Tong, Roman Kats-Kagan, Joel P. Berger, Emma R. Parmee, Brian T. Campbell, Fengqi Zhang, Kaushik Mitra
المصدر: Bioorganicmedicinal chemistry letters. 27(9)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Enzyme Activators, Carbohydrate metabolism, Hypoglycemia, 01 natural sciences, Biochemistry, 03 medical and health sciences, Mice, Internal medicine, Diabetes mellitus, Drug Discovery, Glucokinase, medicine, Distribution (pharmacology), Glucose homeostasis, Animals, Humans, Hypoglycemic Agents, Insulin, Adverse effect, Molecular Biology, Pancreas, Chemistry, Organic Chemistry, medicine.disease, 0104 chemical sciences, Mice, Inbred C57BL, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 2, Liver, Molecular Medicine
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المصدر: Journal of Pharmaceutical Sciences. 99:4973-4981
مصطلحات موضوعية: Chemical Phenomena, Stereochemistry, Chemistry, Pharmaceutical, Pharmaceutical Science, beta-Lactamases, law.invention, Drug Stability, law, Computational chemistry, Phase (matter), Animals, Particle Size, Solubility, Crystallization, Beta-Lactamase Inhibitors, Dissolution, Phase diagram, Aqueous solution, Molecular Structure, Chemistry, Water, Hydrogen Bonding, Bridged Bicyclo Compounds, Heterocyclic, Amorphous solid, Molecular Weight, Pharmaceutical Preparations, Injections, Intravenous, beta-Lactamase Inhibitors
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المؤلفون: Brian T. Farrer, Tsu Chien Weng, Manolis Matzapetakis, Lars Hemmingsen, Vincent L. Pecoraro, James E. Penner-Hahn
المصدر: Journal of the American Chemical Society. 124:8042-8054
مصطلحات موضوعية: Circular dichroism, Stereochemistry, Molecular Sequence Data, chemistry.chemical_element, Peptide, Biochemistry, Catalysis, Arsenic, Metal, Colloid and Surface Chemistry, Metalloproteins, Amino Acid Sequence, Peptide sequence, chemistry.chemical_classification, Trigonal planar molecular geometry, Cadmium, Circular Dichroism, Chemical shift, Mercury, General Chemistry, Bond length, Kinetics, chemistry, visual_art, visual_art.visual_art_medium, Spectrophotometry, Ultraviolet
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المصدر: Biochemistry. 40:14696-14705
مصطلحات موضوعية: Models, Molecular, Coiled coil, Protein Denaturation, Protein Folding, Protein Conformation, Chemistry, Stereochemistry, Spectrum Analysis, Leucines, Mercury, Trigonal crystal system, Hydrogen-Ion Concentration, Biochemistry, Peptide Fragments, Thermodynamic model, Heptad repeat, Crystallography, Drug Stability, Metalloproteins, Thermodynamics, Free energies, Titration, Chromatography, High Pressure Liquid, Guanidine, Cysteine
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المؤلفون: Brian T. Farrer, and Jennifer S. Pickett, H. Holden Thorp
المصدر: Journal of the American Chemical Society. 122:549-553
مصطلحات موضوعية: chemistry.chemical_classification, Hydride, Oligonucleotide, Inorganic chemistry, General Chemistry, Cleavage (embryo), Biochemistry, Medicinal chemistry, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Nucleic acid, Electronic effect, medicine, Nucleotide, Piperidine, Inosine, medicine.drug
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المؤلفون: Brian T. Farrer, H. Holden Thorp
المصدر: Inorganic Chemistry. 38:2497-2502
مصطلحات موضوعية: Inorganic Chemistry, Isotope, Computational chemistry, Chemistry, Kinetics, Physical chemistry, Comproportionation, Physical and Theoretical Chemistry, Proton-coupled electron transfer
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المؤلفون: Robert M. Wenslow, Andrey V. Peresypkin, Brian T. Farrer
المصدر: Journal of pharmaceutical sciences. 96(2)
مصطلحات موضوعية: Materials science, Magnetic Resonance Spectroscopy, Sodium, Analytical chemistry, Pharmaceutical Science, chemistry.chemical_element, law.invention, Polyethylene Glycols, chemistry.chemical_compound, law, Benzopyrans, Crystallization, Suspension (vehicle), Cellulose, Chromatography, High Pressure Liquid, Triglycerides, Phenyl Ethers, Caprylic acid, Microcrystalline cellulose, chemistry, Solubility, Solubilization, Slurry, Pharmaceutical Vehicles, Quantitative analysis (chemistry)
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المؤلفون: Brian T, Farrer, Vincent L, Pecoraro
المصدر: Current opinion in drug discoverydevelopment. 5(6)
مصطلحات موضوعية: Peptide Biosynthesis, Drug Design, Metals, Heavy, Molecular Sequence Data, Animals, Humans, Technology, Pharmaceutical, Amino Acid Sequence, Carrier Proteins, Peptides
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b4d9a40fed5d169926dbf7e134fd9c6f
https://pubmed.ncbi.nlm.nih.gov/12478724
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