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1دورية أكاديمية
المؤلفون: Babak Basiri, Fang Xie, Bin Wu, Sara C. Humphreys, Julie M. Lade, Mai B. Thayer, Pam Yamaguchi, Monica Florio, Brooke M. Rock
المصدر: Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 725-736 (2020)
مصطلحات موضوعية: In vitro in vivo correlation, IVIVC, siRNA, liver homogenate stability, mass spectrometry, metabolite identification, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Mai B. Thayer, Sara C. Humphreys, Kyu S. Chung, Julie M. Lade, Kevin D. Cook, Brooke M. Rock
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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المؤلفون: William C. Fanslow, Kim C. Quon, Matthew M. Bio, Margaret F. Weidner, Wesley S. Chang, Jason W. O'Neill, Christopher J. Borths, Dan A. Rock, Seamus P. Ragan, Sophia Siu, Robert R. Milburn, Sonal K. Patel, Brooke M. Rock, Mark E. Tometsko, Jesse L. Gurgel, Allison P. Jacob, Kevin J. Hamblett
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afd7b980e59ed2ae74732dbadbd5224
https://doi.org/10.1158/0008-5472.22406852 -
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المؤلفون: William C. Fanslow, Kim C. Quon, Matthew M. Bio, Margaret F. Weidner, Wesley S. Chang, Jason W. O'Neill, Christopher J. Borths, Dan A. Rock, Seamus P. Ragan, Sophia Siu, Robert R. Milburn, Sonal K. Patel, Brooke M. Rock, Mark E. Tometsko, Jesse L. Gurgel, Allison P. Jacob, Kevin J. Hamblett
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eff3eb212c549f79dc7834903550168
https://doi.org/10.1158/0008-5472.22406858.v1 -
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المؤلفون: William C. Fanslow, Kim C. Quon, Matthew M. Bio, Margaret F. Weidner, Wesley S. Chang, Jason W. O'Neill, Christopher J. Borths, Dan A. Rock, Seamus P. Ragan, Sophia Siu, Robert R. Milburn, Sonal K. Patel, Brooke M. Rock, Mark E. Tometsko, Jesse L. Gurgel, Allison P. Jacob, Kevin J. Hamblett
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33716785c78c5ac8ae1ee739e76fa395
https://doi.org/10.1158/0008-5472.22406855.v1 -
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المؤلفون: Upendra P. Dahal, Brooke M. Rock, John Rodgers, Xiaomeng Shen, Zhe Wang, Jan L. Wahlstrom
المصدر: Drug Metabolism and Disposition. 50:600-612
مصطلحات موضوعية: Pharmacology, Pharmaceutical Science
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e58aabc5dfac2c30f80ad7fee27c19b9
https://doi.org/10.1124/dmd.121.000798 -
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المؤلفون: Michael J. Koren, Patrick Maurice Moriarty, Seth J. Baum, Joel Neutel, Martha Hernandez-Illas, Howard S. Weintraub, Monica Florio, Helina Kassahun, Stacey Melquist, Tracy Varrieur, Saptarsi M. Haldar, Winnie Sohn, Huei Wang, Mary Elliott-Davey, Brooke M. Rock, Tao Pei, Oliver Homann, Jennifer Hellawell, Gerald F. Watts
المصدر: Nature Medicine. 28:96-103
مصطلحات موضوعية: Adult, Male, Hyperlipidemias, Mice, Transgenic, General Medicine, Middle Aged, General Biochemistry, Genetics and Molecular Biology, Macaca fascicularis, Mice, Animals, Humans, Female, RNA, Small Interfering, Lipoprotein(a)
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المؤلفون: Upendra P, Dahal, Brooke M, Rock, John, Rodgers, Xiaomeng, Shen, Zhe, Wang, Jan L, Wahlstrom
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 50(5)
مصطلحات موضوعية: Proto-Oncogene Proteins p21(ras), Feces, Dogs, Lung Neoplasms, Pyrimidines, Pyridines, Carcinoma, Non-Small-Cell Lung, Animals, Humans, Glutathione, Piperazines, Serum Albumin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::93cc36a2c23298a8a9bfb866a3e35210
https://pubmed.ncbi.nlm.nih.gov/35153196 -
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المؤلفون: Kevin Cook, Brooke M. Rock, Mai B. Thayer, Sara C. Humphreys, Kyu S. Chung, Julie M. Lade
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Analyte, Nucleic acid quantitation, Molecular biology, Science, Oligonucleotides, 030226 pharmacology & pharmacy, Article, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, 0302 clinical medicine, Nucleic Acids, Sense (molecular biology), medicine, Animals, Humans, RNA, Small Interfering, Locked nucleic acid, Immunoassay, Multidisciplinary, medicine.diagnostic_test, Drug discovery, Oligonucleotide, Chemistry, Biological techniques, Rats, 030104 developmental biology, Biochemistry, Nucleic acid, Medicine
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المؤلفون: Mai B. Thayer, Brooke M. Rock, Jabbar Campbell, Sara C. Humphreys, Dan Adams, Wen Li Kelly Chen, Julie M. Lade
المصدر: Journal of Medicinal Chemistry. 63:6407-6422
مصطلحات موضوعية: Drug Evaluation, Preclinical, Design elements and principles, Computational biology, 01 natural sciences, 03 medical and health sciences, Drug Development, Biotransformation, Drug Discovery, Animals, Humans, Tissue Distribution, Product formation, Tissue distribution, RNA, Small Interfering, 030304 developmental biology, ADME, 0303 health sciences, Chemistry, Disposition, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Pharmaceutical Preparations, Drug development, Drug Design, Molecular Medicine