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المؤلفون: Elizabeth Ann Gleason, L. Nathan Tumey, Steven M. Murphy, George Mbella Ekema, Bruce Sherf, Robert W. Mays, Joel Danzig, Jianping Song, John J. Harrington, Marc Palmer, Doug Hanniford, Gary Pawlowski, Michael J. Robarge, Chris Doucette, Margaret Loftus, Karen Hunady, Youssef L. Bennani, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:3287-3290
مصطلحات موضوعية: Indoles, Receptors, Prostaglandin, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Chemical synthesis, Thromboxane A2, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Receptors, Immunologic, Molecular Biology, Prostaglandin D2 receptor, Indole test, Sulfonamides, Esterification, Chemistry, Organic Chemistry, Antagonist, In vitro, Molecular Medicine, Prostaglandin D2, Ramatroban, medicine.drug
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2
المؤلفون: Karen Hunady, Bruce Sherf, John J. Harrington, Chris Doucette, N. Wang, J. Song, Douglas Hanniford, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: ASSAY and Drug Development Technologies. 3:309-318
مصطلحات موضوعية: Genetic Vectors, Histamine Antagonists, Gene Expression, Biology, Transfection, Binding, Competitive, RAGE (receptor), Histamine Agonists, Iodine Radioisotopes, Radioligand Assay, Cell Line, Tumor, Complementary DNA, Drug Discovery, Gene expression, Humans, Receptors, Histamine H3, Technology, Pharmaceutical, Fluorometry, Binding site, Gene, Drug discovery, Imidazoles, Molecular biology, Cell biology, Molecular Medicine, Target protein, Histamine H3 receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3f13b80fc9140bd411ad080a4543d4
https://doi.org/10.1089/adt.2005.3.309 -
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المؤلفون: John J. Harrington, Chris Doucette, Karen Hunady, Doug Hanniford, Margaret Loftus, Varga Norbert, L. Nathan Tumey, Daniel P. Silver, Elizabeth Ann Gleason, David C. Bom, Jianping Song, Joel Danzig, Marc Palmer, Steven M. Murphy, Michael J. Robarge, Gary Pawlowski, Youssef L. Bennani, George Mbella Ekema, Bruce Sherf, Robert W. Mays, Alain Stricker-Krongrad, Kurt R. Brunden
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:1749-1753
مصطلحات موضوعية: Isostere, Receptors, Prostaglandin, Clinical Biochemistry, Carbazoles, Molecular Conformation, Pharmaceutical Science, Prostaglandin, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Isomerism, Drug Discovery, medicine, Anti-Asthmatic Agents, Receptors, Immunologic, Receptor, Molecular Biology, Sulfonamides, Molecular Structure, Organic Chemistry, Antagonist, Chemotaxis, Eosinophil, medicine.anatomical_structure, Models, Chemical, chemistry, Molecular Medicine, Ramatroban, Prostaglandin D2, medicine.drug
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4
المؤلفون: Zhengfan Jiang, George Stark Stark, Joel Danzig, Bruce Sherf, Ge Jin, Alison K. Klika, Xiaoxia Li, Ben Faga, Michelle Callahan, John Harrington
المصدر: Proceedings of the National Academy of Sciences. 101:2028-2033
مصطلحات موضوعية: Molecular Sequence Data, Electrophoretic Mobility Shift Assay, Enzyme-Linked Immunosorbent Assay, Biology, Cell Line, Mice, chemistry.chemical_compound, Genes, Reporter, Gene expression, Animals, Humans, Amino Acid Sequence, Transgenes, Promoter Regions, Genetic, Transcription factor, Adaptor Proteins, Signal Transducing, TNF Receptor-Associated Factor 6, Regulation of gene expression, Multidisciplinary, MAP kinase kinase kinase, Kinase, Interleukin-8, Intracellular Signaling Peptides and Proteins, NF-kappa B, Computational Biology, Proteins, NF-κB, Biological Sciences, MAP Kinase Kinase Kinases, NFKB1, Molecular biology, Cell biology, Gene Expression Regulation, chemistry, NIH 3T3 Cells, Carrier Proteins, Peptides, Transforming growth factor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d311a615ee515329b9f09faf2f169
https://doi.org/10.1073/pnas.0307314101 -
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المؤلفون: Anthony E. Ting, Alain Stricker-Krongrad, Kurt R. Brunden, E Graham, J. Song, Douglas Hanniford, M F Poole, John J. Harrington, Chris Doucette, Bruce Sherf
المصدر: Assay and drug development technologies. 3(6)
مصطلحات موضوعية: Agonist, medicine.medical_specialty, Serotonin, medicine.drug_class, Drug Evaluation, Preclinical, Pharmacology, Biology, Transfection, Binding, Competitive, Cell Line, Radioligand Assay, Internal medicine, Drug Discovery, Receptor, Serotonin, 5-HT2B, medicine, Receptor, Serotonin, 5-HT2C, Humans, Receptor, Serotonin, 5-HT2A, Calcium Signaling, Ergolines, Receptor, Dose-Response Relationship, Drug, 5-HT2 receptor, Amphetamines, Serotonin Receptor Agonists, Lysergic Acid Diethylamide, Endocrinology, Scintillation proximity assay, Molecular Medicine, Ketanserin, Serotonin Antagonists, Signal transduction, Endogenous agonist, Serotonin 5-HT2 Receptor Agonists
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1800a42af4f6eba00ba0aea30e3c6fe
https://pubmed.ncbi.nlm.nih.gov/16438660 -
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المؤلفون: Joel Danzig, Sikander Gill, Steven M. Murphy, Karen Hunady, Linas Padegimas, Anthony E. Ting, Alain Stricker-Krongrad, Kurt R. Brunden, Rajwant Gill, Bruce Sherf, Marc Palmer, Michelle Fontilla Poole
المصدر: Journal of pharmacological and toxicological methods. 54(1)
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, ERG1 Potassium Channel, hERG, CHO Cells, Pharmacology, Toxicology, QT interval, Sudden death, Cell Line, Radioligand Assay, Cricetinae, Animals, Humans, cardiovascular diseases, Patch clamp, Membrane potential, biology, Chemistry, Ligand binding assay, Chinese hamster ovary cell, Potassium channel, Ether-A-Go-Go Potassium Channels, Recombinant Proteins, biology.protein, Protein Binding
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المؤلفون: John J. Harrington, Bruce Sherf, Kurt R. Brunden
المصدر: Pharmacogenomics. 6(4)
مصطلحات موضوعية: Pharmacology, Genetics, Reverse pharmacology, Genome, Organisms, Genetically Modified, Drug discovery, Emerging technologies, Drug Evaluation, Preclinical, Computational biology, Biology, RAGE (receptor), Drug Delivery Systems, Pharmacogenetics, Drug Design, Molecular Medicine, Animals, Humans, Identification (biology), Human genome, Gene, Nucleic Acid Amplification Techniques
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المؤلفون: Steven M. Murphy, Bruce Sherf, Tom Dent, Daniel P. Silver, Andrew Bailey, L. Nathan Tumey, Jianmin Wang, Youssef L. Bennani, Elizabeth Ann Gleason, David C. Bom, Bayard Huck, Christina Leventhal, Sherry Boozer, John J. Harrington, Stephen Rundlett, Kurt R. Brunden
المصدر: Bioorganicmedicinal chemistry letters. 15(2)
مصطلحات موضوعية: Xeroderma pigmentosum, DNA repair, DNA damage, Flap Endonucleases, Clinical Biochemistry, Flap structure-specific endonuclease 1, Pharmaceutical Science, Biochemistry, Endonuclease, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Temozolomide, Humans, Urea, Enzyme Inhibitors, Molecular Biology, Xeroderma Pigmentosum, biology, Organic Chemistry, Base excision repair, medicine.disease, Methyl Methanesulfonate, Methyl methanesulfonate, Dacarbazine, chemistry, Urinary Bladder Neoplasms, biology.protein, Molecular Medicine, Nucleotide excision repair, DNA Damage
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المؤلفون: Jianmin Wang, John J. Harrington, Daniel P. Silver, Bayard Huck, Kurt R. Brunden, Christina Leventhal, Bruce Sherf, L. Nathan Tumey, Tom Dent, Steven M. Murphy, Elizabeth Ann Gleason, Andrew Bailey, Sherry Boozer, Stephen Rundlett, Youssef L. Bennani
المصدر: Bioorganicmedicinal chemistry letters. 14(19)
مصطلحات موضوعية: chemistry.chemical_classification, biology, DNA damage, DNA repair, Flap Endonucleases, Organic Chemistry, Clinical Biochemistry, Flap structure-specific endonuclease 1, Pharmaceutical Science, Base excision repair, Biochemistry, Endonuclease, chemistry.chemical_compound, Butyrates, Structure-Activity Relationship, Enzyme, chemistry, Drug Discovery, biology.protein, Molecular Medicine, Flap endonuclease, Enzyme Inhibitors, Molecular Biology, DNA
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المؤلفون: Kalok Lo, Neil Veloso, Kevin Cothren, Rakesh Ramachandran, Matthew D. Ducar, Laura Lerner, John J. Harrington, Emery Smith, Robert W. Mays, Joel Danzig, Dana Costanzo, Scott Cain, Christina Leventhal, P. David Jackson, Sherry Boozer, Jennifer Hess, Mark Thornton, Stephen Rundlett, Karen McElligott, Bruce Sherf, Rob Perry, Jessica Whittington, Jason Offenbacher, Alison K. Klika
المصدر: Nature biotechnology. 19(5)
مصطلحات موضوعية: endocrine system diseases, Databases, Factual, Molecular Sequence Data, Biomedical Engineering, Bioengineering, Enzyme-Linked Immunosorbent Assay, Biology, Applied Microbiology and Biotechnology, RAGE (receptor), Cell Line, Gene Frequency, Complementary DNA, Gene expression, Humans, Genomic library, Gene, Sequence Tagged Sites, Regulation of gene expression, Genetics, Expressed Sequence Tags, Expressed sequence tag, Genomic Library, Genome, Human, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Proteins, Gene expression profiling, Gene Expression Regulation, Genetic Techniques, Multigene Family, cardiovascular system, Molecular Medicine, Biotechnology