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المؤلفون: Mark A. Nagy, Robert Hilgraf, Deborah S. Mortensen, Jan Elsner, Stephen Norris, Jayashree Tikhe, Won Yoon, David Paisner, Mercedes Delgado, Paul Erdman, Jason Haelewyn, Godrej Khambatta, Li Xu, William J. Romanow, Kevin Condroski, Sogole Bahmanyar, Meg McCarrick, Brent Benish, Kate Blease, Laurie LeBrun, Mehran F. Moghaddam, Julius Apuy, Stacie S. Canan, Brydon L. Bennett, Yoshitaka Satoh
المصدر: Journal of Medicinal Chemistry. 64:18193-18208
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Mark A, Nagy, Robert, Hilgraf, Deborah S, Mortensen, Jan, Elsner, Stephen, Norris, Jayashree, Tikhe, Won, Yoon, David, Paisner, Mercedes, Delgado, Paul, Erdman, Jason, Haelewyn, Godrej, Khambatta, Li, Xu, William J, Romanow, Kevin, Condroski, Sogole, Bahmanyar, Meg, McCarrick, Brent, Benish, Kate, Blease, Laurie, LeBrun, Mehran F, Moghaddam, Julius, Apuy, Stacie S, Canan, Brydon L, Bennett, Yoshitaka, Satoh
المصدر: Journal of medicinal chemistry. 64(24)
مصطلحات موضوعية: Cyclohexylamines, Structure-Activity Relationship, Pyrimidines, Drug Discovery, JNK Mitogen-Activated Protein Kinases, Animals, Humans, Phosphorylation, Protein Kinase Inhibitors, Idiopathic Pulmonary Fibrosis, Substrate Specificity
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المؤلفون: Weilin Xie, Jean Lachowicz, Timothy Hoey, Igor Belka, Paola Castiglioni, James Hartke, Steven D. Nathan, Leon Carayannopoulos, David A. Brenner, Matthew C. Groza, Ann M. Kapoun, Cho Ho, Nai-Yu Wang, Austin L. Gurney, Mingjun Zhang, Brent Benish, Jörg H W Distler, Michael Haughey, Jennifer Cain, Kate Blease, Suzana Couto, Brydon L. Bennett, Hariharan Kandasamy, Clifton Drew
المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0229445 (2020)مصطلحات موضوعية: 0301 basic medicine, Male, Chemokine, Biochemistry, Epithelium, Idiopathic pulmonary fibrosis, Mice, 0302 clinical medicine, Medizinische Fakultät, Fibrosis, Animal Cells, Non-alcoholic Fatty Liver Disease, Medicine and Health Sciences, Wnt Signaling Pathway, Cells, Cultured, Connective Tissue Cells, Multidisciplinary, biology, Liver Diseases, Wnt signaling pathway, Animal Models, Experimental Organism Systems, Liver, Connective Tissue, Mice, Inbred DBA, 030220 oncology & carcinogenesis, Medicine, Liver Fibrosis, Signal transduction, Cellular Types, Anatomy, Research Article, Science, Mouse Models, Gastroenterology and Hepatology, Research and Analysis Methods, Antibodies, 03 medical and health sciences, Model Organisms, In vivo, medicine, Animals, Humans, ddc:610, RSPO1, Immunohistochemistry Techniques, RSPO3, business.industry, Biology and Life Sciences, Proteins, Epithelial Cells, Cell Biology, Fibroblasts, medicine.disease, Idiopathic Pulmonary Fibrosis, Histochemistry and Cytochemistry Techniques, 030104 developmental biology, Biological Tissue, Cancer research, biology.protein, Immunologic Techniques, Animal Studies, Hepatocytes, business, Thrombospondins, Collagens, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Brydon L. Bennett, Gerald Horan, Steven Greenberg, Kate Blease, Francisco Ramírez-Valle, Peter H. Schafer, Ada Azaryan, Ralph Ceres, Ying Ye
المصدر: Diffuse Parenchymal Lung Disease.
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, business.industry, Kinase, medicine.disease, 030226 pharmacology & pharmacy, Gastroenterology, Jnk inhibitor, First generation, 03 medical and health sciences, FEV1/FVC ratio, 030104 developmental biology, 0302 clinical medicine, Internal medicine, Pulmonary fibrosis, Medicine, Disease biomarker, In patient, business, Lung function
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa86ea896b3e0b594fd1f97f75f36a2e
https://doi.org/10.1183/1393003.congress-2017.oa474 -
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المؤلفون: Mahmoud Assaf, Jos van der Velden, Nasreen Khalil, Peter H. Schafer, Ying Ye, William T. Smith, Gerald Horan, Rajesh Chopra, Maria Palmisano, Peng Chen, Yvonne M. W. Janssen-Heininger, Sidra M. Hoffman, Brydon L. Bennett, Zebulun Horowitz, R. Stevens, Sarah Abdalla, Karolyn G. Lahue, Donna Sutherland, James D. Nolin, Yong Liu, David G. Chapman
المصدر: Clinical and Translational Medicine
مصطلحات موضوعية: 0301 basic medicine, Matrix metalloproteinase 7, Pathology, medicine.medical_specialty, CC-930, Medicine (miscellaneous), Idiopathic pulmonary fibrosis, Tenascin-C, Gastroenterology, 03 medical and health sciences, FEV1/FVC ratio, Internal medicine, Pulmonary fibrosis, medicine, Adverse effect, Lung, medicine.diagnostic_test, business.industry, Research, Surfactant protein D, respiratory system, medicine.disease, respiratory tract diseases, 030104 developmental biology, Bronchoalveolar lavage, medicine.anatomical_structure, Molecular Medicine, Biomarker (medicine), JNK, business, Biomarkers, Progressive disease
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398cdbb0b157c2291e7780fcbc8ffb6b
https://hdl.handle.net/10453/130399 -
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المؤلفون: Gregory D. Ferguson, Frans Baculi, Kristen Jensen-Pergakes, Maria Celeridad, Steven Pierce, Barbra Pagarigan, Garrick Packard, Matt Hickman, Brydon L. Bennett, Yang Tang, Li Xu, Veronique Plantevin-Krenitsky, Sanaa Torres, Lisa Nadolny, Lida Tehrani, R. J. Bates, Trish Nguyen, Jason Haelewyn, Kelven Burnett, Laurie LeBrun, Philip P Chamberlain, Weilin Xie, Kate Blease, Keiji Miyazawa, Mercedes Delgado, Pilgrim Jackson, Heather Brown
المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0145705 (2016)مصطلحات موضوعية: 0301 basic medicine, Male, Neutrophils, Pyridines, lcsh:Medicine, Syk, Arthritis, Receptors, Fc, Crystallography, X-Ray, Rats, Sprague-Dawley, 0302 clinical medicine, Medicine, Edema, Kinome, lcsh:Science, Receptor, Skin, Multidisciplinary, Kinase, Intracellular Signaling Peptides and Proteins, hemic and immune systems, Protein-Tyrosine Kinases, Basophils, Hypertension, Female, Collagen, Tyrosine kinase, Research Article, Indazoles, Neutropenia, chemical and pharmacologic phenomena, Cell Line, 03 medical and health sciences, Inhibitory Concentration 50, Immune system, Animals, Humans, Syk Kinase, Inflammation, Dose-Response Relationship, Drug, business.industry, lcsh:R, Autoantibody, Janus Kinase 2, Triazoles, medicine.disease, Arthritis, Experimental, Vascular Endothelial Growth Factor Receptor-2, Rats, Eosinophils, 030104 developmental biology, HEK293 Cells, Rats, Inbred Lew, Immunology, Cancer research, lcsh:Q, business, 030215 immunology
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المؤلفون: David J. Nikolic-Paterson, Brydon L. Bennett, Robert S Flanc, Frank Y. Ma, Glenn C. Friedman, Greg H. Tesch
المصدر: Laboratory Investigation. 89:470-484
مصطلحات موضوعية: medicine.medical_specialty, Anti-Glomerular Basement Membrane Disease, Kidney Glomerulus, urologic and male genital diseases, Rats, Inbred WKY, Pathology and Forensic Medicine, Proinflammatory cytokine, Internal medicine, Animals, Medicine, Macrophage, Pyrazolones, Molecular Biology, Kidney, biology, urogenital system, business.industry, Kinase, Macrophages, JNK Mitogen-Activated Protein Kinases, Glomerulonephritis, Cell Biology, medicine.disease, female genital diseases and pregnancy complications, Rats, Blockade, Endocrinology, medicine.anatomical_structure, Gene Expression Regulation, Mitogen-activated protein kinase, Antibody Formation, biology.protein, Female, business, Signal Transduction, Kidney disease
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المؤلفون: Keiichi Mitsuyama, Kazuyo Handa, Osamu Tsuruta, Yutaka Matsui, Nobuo Tomiyasu, Atsushi Toyonaga, J. Masuda, Yoshitaka Satoh, Brydon L. Bennett, Kazunori Harada, Asuka Suzuki, Kosuke Takaki, Michio Sata
المصدر: Clinical and Experimental Immunology. 143:24-29
مصطلحات موضوعية: Time Factors, p38 mitogen-activated protein kinases, Blotting, Western, Immunology, Biology, p38 Mitogen-Activated Protein Kinases, Rats, Sprague-Dawley, Lesion, Extracellular, medicine, Animals, Immunology and Allergy, Enzyme Inhibitors, Extracellular Signal-Regulated MAP Kinases, Anthracenes, Ethanol, Kinase, Stomach, c-jun, JNK Mitogen-Activated Protein Kinases, Immunohistochemistry, Rats, Enzyme Activation, medicine.anatomical_structure, Gastric Mucosa, Gastritis, Animal Studies, Phosphorylation, Female, Signal transduction, medicine.symptom, Signal Transduction
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المؤلفون: Brydon L. Bennett, Kian Fan Chung, Ian M. Adcock, Paul R. Eynott, Sum-Yee Leung, Puneeta Nath
المصدر: European Journal of Pharmacology. 506:273-283
مصطلحات موضوعية: Male, medicine.medical_specialty, Inflammation, Mice, Internal medicine, medicine, Animals, Protein kinase A, Lung, Anthracenes, Pharmacology, Mice, Inbred BALB C, Dose-Response Relationship, Drug, medicine.diagnostic_test, biology, Kinase, business.industry, JNK Mitogen-Activated Protein Kinases, respiratory system, Eosinophil, medicine.disease, Asthma, respiratory tract diseases, Ovalbumin, medicine.anatomical_structure, Bronchoalveolar lavage, Endocrinology, Bronchial hyperresponsiveness, Immunology, biology.protein, Bronchial Hyperreactivity, medicine.symptom, business, Respiratory tract
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المؤلفون: Jeffrey A. Muir, Brydon L. Bennett, Timothy C. Chambers, William A. Gaarde, Toria B. Obey, Christopher S. Lyle, Lihua Du
المصدر: Journal of Biological Chemistry. 279:11957-11966
مصطلحات موضوعية: Cyclin-dependent kinase 1, biology, Kinase, Cell growth, p38 mitogen-activated protein kinases, Cyclin-dependent kinase 2, Cyclin B, Cell Biology, Cell cycle, Biochemistry, Cell biology, biology.protein, Cancer research, Protein kinase A, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cc1b5e09713f11f32d9d3873e6dc992f
https://doi.org/10.1074/jbc.m304935200
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