المؤلفون: Silva PA; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil., Souza AA; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil., de Oliveira GM; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil., Ramada MHS; Programa de Pós-graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, 70790-160, Brazil., Hernández NV; Departmento de Biologia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, 36050, Mexico., Mora-Montes HM; Departmento de Biologia, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Guanajuato, 36050, Mexico., Bueno RV; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil., Martins-de-Sa D; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil.; Genesilico Biotech, Brasília, DF, Brazil., de Freitas SM; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil., Felipe MSS; Programa de Pós-graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília, Brasília, 70790-160, Brazil., Barbosa JARG; Laboratório de Biofísica Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, 70910-900, Brazil. joaobarbosa@unb.br.

المصدر: Fungal biology and biotechnology [Fungal Biol Biotechnol] 2024 May 07; Vol. 11 (1), pp. 5. Date of Electronic Publication: 2024 May 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101655873 Publication Model: Electronic Cited Medium: Internet ISSN: 2054-3085 (Electronic) Linking ISSN: 20543085 NLM ISO Abbreviation: Fungal Biol Biotechnol Subsets: PubMed not MEDLINE

المؤلفون: Garcia ML; Sao Carlos Institute of Physics, University of Sao Paulo, São Carlos, São Paulo, Brazil., de Oliveira AA; Sao Carlos Institute of Physics, University of Sao Paulo, São Carlos, São Paulo, Brazil., Bueno RV; Sao Carlos Institute of Physics, University of Sao Paulo, São Carlos, São Paulo, Brazil., Nogueira VHR; Sao Carlos Institute of Physics, University of Sao Paulo, São Carlos, São Paulo, Brazil., de Souza GE; Sao Carlos Institute of Physics, University of Sao Paulo, São Carlos, São Paulo, Brazil., Guido RVC; Sao Carlos Institute of Physics, University of Sao Paulo, São Carlos, São Paulo, Brazil.

المصدر: Drug development research [Drug Dev Res] 2022 Apr; Vol. 83 (2), pp. 264-284. Date of Electronic Publication: 2020 Feb 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

مواضيع طبية MeSH: Plasmodium falciparum* , Quantitative Structure-Activity Relationship*, Acyltransferases ; Humans ; Reproducibility of Results ; Thiophenes

المؤلفون: Bueno RV; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Davis S; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Dawson A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Ondachi PW; Research Triangle Institute, PO Box 12194, Research Triangle Park, Durham, NC 27709, USA., Carroll FI; Research Triangle Institute, PO Box 12194, Research Triangle Park, Durham, NC 27709, USA., Hunter WN; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.

المصدر: Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2022 Mar 01; Vol. 78 (Pt 3), pp. 353-362. Date of Electronic Publication: 2022 Feb 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101676043 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7983 (Electronic) Linking ISSN: 20597983 NLM ISO Abbreviation: Acta Crystallogr D Struct Biol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Nicotinic*/chemistry , Receptors, Nicotinic*/metabolism, Acetylcholine/chemistry ; Acetylcholine/metabolism ; Bridged Bicyclo Compounds, Heterocyclic/chemistry ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Carrier Proteins/chemistry ; Humans ; Pyridines

المؤلفون: Politi FAS; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara (SP), Brazil. Electronic address: flaviopoliti@hotmail.com., Bueno RV; University of São Paulo (USP), Physics Institute of São Carlos (IFSC), São Carlos (SP), Brazil., Zeoly LA; University of Campinas (UNICAMP), Chemistry Institute, Campinas (SP), Brazil., Fantatto RR; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara (SP), Brazil., Eloy JO; College of Pharmacy, Dentistry and Nursing, Federal University of Ceará (UFC), Fortaleza (CE), Brazil., Chorilli M; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara (SP), Brazil., Coelho F; University of Campinas (UNICAMP), Chemistry Institute, Campinas (SP), Brazil., Guido RVC; University of São Paulo (USP), Physics Institute of São Carlos (IFSC), São Carlos (SP), Brazil., Chagas ACS; Brazilian Agricultural Research Corporation (EMBRAPA), Southeast Livestock, São Carlos (SP), Brazil., Furlan M; Chemistry Institute, São Paulo State University (UNESP), Araraquara (SP), Brazil.

المصدر: Acta tropica [Acta Trop] 2021 Jul; Vol. 219, pp. 105920. Date of Electronic Publication: 2021 Apr 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6254 (Electronic) Linking ISSN: 0001706X NLM ISO Abbreviation: Acta Trop Subsets: MEDLINE

مواضيع طبية MeSH: Haemonchus/*drug effects , Nanostructures/*chemistry , Thiophenes/*chemistry , Thiophenes/*pharmacology, Animals ; Anthelmintics/chemistry ; Anthelmintics/pharmacology ; Anthelmintics/therapeutic use ; Asteraceae/chemistry ; Drug Compounding ; Feces/parasitology ; Haemonchiasis/drug therapy ; Haemonchus/physiology ; Parasite Egg Count/veterinary ; Sheep ; Sheep Diseases/parasitology ; Thiophenes/therapeutic use

المؤلفون: Fernandes RS; Physics Institute of São Carlos, University of São Paulo, São Carlos 13566-590, SP, Brazil., Freire MCLC; Physics Institute of São Carlos, University of São Paulo, São Carlos 13566-590, SP, Brazil., Bueno RV; Physics Institute of São Carlos, University of São Paulo, São Carlos 13566-590, SP, Brazil., Godoy AS; Physics Institute of São Carlos, University of São Paulo, São Carlos 13566-590, SP, Brazil., Gil LHVG; Instituto Aggeu Magalhães, IAM-FIOCRUZ, Recife 50670-420, PE, Brazil., Oliva G; Physics Institute of São Carlos, University of São Paulo, São Carlos 13566-590, SP, Brazil.

المصدر: Viruses [Viruses] 2020 May 30; Vol. 12 (6). Date of Electronic Publication: 2020 May 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Drug Discovery/*methods , Genes, Reporter/*physiology , RNA Viruses/*drug effects , Replicon/*physiology, Animals ; Antiviral Agents/chemistry ; Cell Line ; Chlorocebus aethiops ; Cricetinae ; Humans ; RNA Viruses/genetics ; Transfection ; Vero Cells

المؤلفون: de Souza GE; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., Bueno RV; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., de Souza JO; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., Zanini CL; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., Cruz FC; Department of Pharmacology, Federal University of São Paulo, Rua Botucatu 862, São Paulo, SP, 04023-062, Brazil., Oliva G; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil., Guido RVC; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil. rvcguido@usp.br., Aguiar ACC; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP, 13563-120, Brazil. carolcaguiar@yahoo.com.br.

المصدر: Malaria journal [Malar J] 2019 Dec 30; Vol. 18 (1), pp. 447. Date of Electronic Publication: 2019 Dec 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

مواضيع طبية MeSH: Drug Combinations*, Antimalarials/*pharmacology , Artesunate/*pharmacology , Plasmodium berghei/*drug effects , Plasmodium falciparum/*drug effects, Antimalarials/toxicity ; Artesunate/toxicity ; Hep G2 Cells ; Humans ; Malaria, Falciparum/prevention & control ; Toxicity Tests

المؤلفون: Okada-Junior CY; Nuclei of Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Department of Organic Chemistry, Institute of Chemistry, and Laboratory of Medicinal Chemistry, Organic Synthesis and Molecular Modeling (LaQMedSOMM), Department of Organic Chemistry, Institute of Chemistry, São Paulo State University-UNESP, Rua Professor Francisco Degni, 55, Jardim Quitandinha, 14800-060 Araraquara, São Paulo, Brazil., Monteiro GC; Nuclei of Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Department of Organic Chemistry, Institute of Chemistry, and Laboratory of Medicinal Chemistry, Organic Synthesis and Molecular Modeling (LaQMedSOMM), Department of Organic Chemistry, Institute of Chemistry, São Paulo State University-UNESP, Rua Professor Francisco Degni, 55, Jardim Quitandinha, 14800-060 Araraquara, São Paulo, Brazil., Aguiar ACC; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, Sao Carlos, São Paulo 13563-120, Brazil., Batista VS; Nuclei of Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Department of Organic Chemistry, Institute of Chemistry, and Laboratory of Medicinal Chemistry, Organic Synthesis and Molecular Modeling (LaQMedSOMM), Department of Organic Chemistry, Institute of Chemistry, São Paulo State University-UNESP, Rua Professor Francisco Degni, 55, Jardim Quitandinha, 14800-060 Araraquara, São Paulo, Brazil., de Souza JO; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, Sao Carlos, São Paulo 13563-120, Brazil., Souza GE; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, Sao Carlos, São Paulo 13563-120, Brazil., Bueno RV; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, Sao Carlos, São Paulo 13563-120, Brazil., Oliva G; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, Sao Carlos, São Paulo 13563-120, Brazil., Nascimento-Júnior NM; Nuclei of Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Department of Organic Chemistry, Institute of Chemistry, and Laboratory of Medicinal Chemistry, Organic Synthesis and Molecular Modeling (LaQMedSOMM), Department of Organic Chemistry, Institute of Chemistry, São Paulo State University-UNESP, Rua Professor Francisco Degni, 55, Jardim Quitandinha, 14800-060 Araraquara, São Paulo, Brazil., Guido RVC; Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, Sao Carlos, São Paulo 13563-120, Brazil., Bolzani VS; Nuclei of Bioassays, Biosynthesis and Ecophysiology of Natural Products (NuBBE), Department of Organic Chemistry, Institute of Chemistry, and Laboratory of Medicinal Chemistry, Organic Synthesis and Molecular Modeling (LaQMedSOMM), Department of Organic Chemistry, Institute of Chemistry, São Paulo State University-UNESP, Rua Professor Francisco Degni, 55, Jardim Quitandinha, 14800-060 Araraquara, São Paulo, Brazil.

المصدر: ACS omega [ACS Omega] 2018 Aug 20; Vol. 3 (8), pp. 9424-9430. Date of Electronic Publication: 2018 Aug 20 (Print Publication: 2018).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE

المؤلفون: Panwar P; Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada.; Center for Blood Research, Vancouver, BC, Canada.; Clinical Cell Biology, Vejle Hospital/Lillebaelt Hospital, Institute of Regional Health Research, University of Southern Denmark, Vejle, Denmark., Søe K; Clinical Cell Biology, Vejle Hospital/Lillebaelt Hospital, Institute of Regional Health Research, University of Southern Denmark, Vejle, Denmark., Guido RV; Laboratório de Química Medicinal e Computacional, Centro de Inovação em Biodiversidade e Fármacos, Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, Brazil., Bueno RV; Laboratório de Química Medicinal e Computacional, Centro de Inovação em Biodiversidade e Fármacos, Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, Brazil., Delaisse JM; Clinical Cell Biology, Vejle Hospital/Lillebaelt Hospital, Institute of Regional Health Research, University of Southern Denmark, Vejle, Denmark., Brömme D; Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada.; Center for Blood Research, Vancouver, BC, Canada.; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

المصدر: British journal of pharmacology [Br J Pharmacol] 2016 Jan; Vol. 173 (2), pp. 396-410. Date of Electronic Publication: 2015 Dec 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Abietanes/*metabolism , Biphenyl Compounds/*metabolism , Bone Resorption/*metabolism , Cathepsin K/*antagonists & inhibitors , Cathepsin K/*metabolism, Abietanes/pharmacology ; Abietanes/therapeutic use ; Animals ; Biphenyl Compounds/pharmacology ; Biphenyl Compounds/therapeutic use ; Bone Resorption/drug therapy ; Cathepsin K/chemistry ; Cattle ; Dose-Response Relationship, Drug ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Osteoclasts/drug effects ; Osteoclasts/metabolism ; Protein Structure, Tertiary

المؤلفون: Bueno RV, Braga RC, Segretti ND, Ferreira EI, Trossini GH, Andrade CH; LabMol, Faculdade de Farmacia, Universidade Federal de Goias, 1a. Av. com Praca Universitaria, Setor Universitario, Goiania - GO, 74605-220, Brazil. carolina@ufg.br.

المصدر: Current pharmaceutical design [Curr Pharm Des] 2014; Vol. 20 (27), pp. 4474-85.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9602487 Publication Model: Print Cited Medium: Internet ISSN: 1873-4286 (Electronic) Linking ISSN: 13816128 NLM ISO Abbreviation: Curr Pharm Des Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Antitubercular Agents/*chemistry , Mycobacterium tuberculosis/*drug effects , Nucleic Acids/*biosynthesis , Tuberculosis, Multidrug-Resistant/*drug therapy, Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Extensively Drug-Resistant Tuberculosis/drug therapy ; Extensively Drug-Resistant Tuberculosis/microbiology ; Humans ; Molecular Structure ; Mycobacterium tuberculosis/enzymology ; Mycobacterium tuberculosis/metabolism ; Quantitative Structure-Activity Relationship ; Tuberculosis, Multidrug-Resistant/microbiology

المؤلفون: Neves BJ; Laboratório de Planejamento de Fármacos e Estudos de Metabolismo por Modelagem Molecular, Faculdade de Farmácia, Universidade Federal de Goiás, Praça Universitária com 1a Av, Goiânia GO 74605-220, Brazil., Bueno RV, Braga RC, Andrade CH

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2013 Apr 15; Vol. 23 (8), pp. 2436-41. Date of Electronic Publication: 2013 Feb 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Antimalarials/*chemistry , Antimalarials/*pharmacology , Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/*antagonists & inhibitors , Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/*chemistry , Plasmodium falciparum/*enzymology , Rhodanine/*analogs & derivatives , Rhodanine/*pharmacology, Binding Sites ; Drug Design ; Drug Discovery ; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism ; Humans ; Ligands ; Models, Molecular ; Plasmodium falciparum/drug effects ; Protein Binding ; Quantitative Structure-Activity Relationship ; Rhodanine/chemistry