المؤلفون: FitzGerald EA; Department of Chemistry - BMC, Uppsala University Uppsala 751 23 Sweden helena.danielson@kemi.uu.se.; Beactica Therapeutics Virdings allé 2 Uppsala 754 40 Sweden., Butko MT; Biodesy, Inc. 170 Harbor Way South San Francisco 94080 CA USA., Boronat P; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam De Boelelaan 1108 1081 HZ Amsterdam The Netherlands., Cederfelt D; Department of Chemistry - BMC, Uppsala University Uppsala 751 23 Sweden helena.danielson@kemi.uu.se., Abramsson M; Department of Chemistry - BMC, Uppsala University Uppsala 751 23 Sweden helena.danielson@kemi.uu.se., Ludviksdottir H; Department of Chemistry - BMC, Uppsala University Uppsala 751 23 Sweden helena.danielson@kemi.uu.se., van Muijlwijk-Koezen JE; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam De Boelelaan 1108 1081 HZ Amsterdam The Netherlands., de Esch IJP; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam De Boelelaan 1108 1081 HZ Amsterdam The Netherlands., Dobritzsch D; Department of Chemistry - BMC, Uppsala University Uppsala 751 23 Sweden helena.danielson@kemi.uu.se., Young T; Biodesy, Inc. 170 Harbor Way South San Francisco 94080 CA USA., Danielson UH; Department of Chemistry - BMC, Uppsala University Uppsala 751 23 Sweden helena.danielson@kemi.uu.se.; Science for Life Laboratory, Uppsala University Sweden.

المصدر: RSC advances [RSC Adv] 2021 Feb 17; Vol. 11 (13), pp. 7527-7537. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE

المؤلفون: Birman Y; Biodesy, Inc., South San Francisco 94080, United States., Khorsand S; Biodesy, Inc., South San Francisco 94080, United States., Tu E; Biodesy, Inc., South San Francisco 94080, United States., Mortensen RB; Biodesy, Inc., South San Francisco 94080, United States., Butko MT; Biodesy, Inc., South San Francisco 94080, United States. Electronic address: margaret.butko@biodesy.com.

المصدر: Methods (San Diego, Calif.) [Methods] 2019 Sep 01; Vol. 167, pp. 92-104. Date of Electronic Publication: 2019 May 19.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9426302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9130 (Electronic) Linking ISSN: 10462023 NLM ISO Abbreviation: Methods Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery/*methods , High-Throughput Screening Assays/*methods , Nucleic Acid Conformation/*drug effects , RNA/*drug effects, Caffeine/chemistry ; Humans ; Ligands ; RNA/chemistry ; Theophylline/chemistry ; Theophylline/pharmacology

المؤلفون: Rizvi NF; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Howe JA; Merck & Co., Inc. , Kenilworth , New Jersey 07033 , United States., Nahvi A; Merck & Co., Inc. , West Point , Pennsylvania 19486 , United States., Klein DJ; Merck & Co., Inc. , West Point , Pennsylvania 19486 , United States., Fischmann TO; Merck & Co., Inc. , Kenilworth , New Jersey 07033 , United States., Kim HY; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., McCoy MA; Merck & Co., Inc. , Kenilworth , New Jersey 07033 , United States., Walker SS; Merck & Co., Inc. , Kenilworth , New Jersey 07033 , United States., Hruza A; Merck & Co., Inc. , Kenilworth , New Jersey 07033 , United States., Richards MP; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Chamberlin C; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Saradjian P; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Butko MT; Biodesy, Inc. , South San Francisco , California 94080 , United States., Mercado G; Biodesy, Inc. , South San Francisco , California 94080 , United States., Burchard J; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Strickland C; Merck & Co., Inc. , Kenilworth , New Jersey 07033 , United States., Dandliker PJ; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Smith GF; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States., Nickbarg EB; Merck & Co., Inc. , Boston , Massachusetts 02115 , United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2018 Mar 16; Vol. 13 (3), pp. 820-831. Date of Electronic Publication: 2018 Feb 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery* , Small Molecule Libraries*, Mass Spectrometry/*methods , RNA/*metabolism, Crystallography, X-Ray ; Flavin Mononucleotide/metabolism ; Ligands ; Molecular Structure ; Pyrimidines/metabolism ; Pyrimidines/pharmacology ; Riboswitch

المؤلفون: Young TA; Biodesy, Inc., South San Francisco, CA, United States., Moree B; Biodesy, Inc., South San Francisco, CA, United States., Butko MT; Biodesy, Inc., South San Francisco, CA, United States., Clancy B; Biodesy, Inc., South San Francisco, CA, United States., Geck Do M; The University of Texas MD Anderson Cancer Center, Institute for Applied Cancer Science, Houston, TX, United States., Gheyi T; Lilly Biotechnology Center, San Diego, CA, United States., Strelow J; Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, United States., Carrillo JJ; Lilly Biotechnology Center, San Diego, CA, United States., Salafsky J; Biodesy, Inc., South San Francisco, CA, United States. Electronic address: joshua.salafsky@biodesy.com.

المصدر: Methods in enzymology [Methods Enzymol] 2018; Vol. 610, pp. 167-190. Date of Electronic Publication: 2018 Oct 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7988 (Electronic) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery/*methods , High-Throughput Screening Assays/*methods , Oligonucleotides/*metabolism , Peptides/*metabolism , Proteins/*metabolism, Animals ; Drug Discovery/instrumentation ; Equipment Design ; High-Throughput Screening Assays/instrumentation ; Humans ; Ligands ; Nucleic Acid Conformation/drug effects ; Oligonucleotides/chemistry ; Peptides/chemistry ; Protein Conformation/drug effects ; Proteins/chemistry

المؤلفون: Adams SR; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: sadams@ucsd.edu., Mackey MR; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Ramachandra R; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Palida Lemieux SF; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Steinbach P; Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093, USA., Bushong EA; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Butko MT; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Giepmans BNG; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA., Ellisman MH; National Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA., Tsien RY; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.

المصدر: Cell chemical biology [Cell Chem Biol] 2016 Nov 17; Vol. 23 (11), pp. 1417-1427. Date of Electronic Publication: 2016 Nov 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Lanthanoid Series Elements/*analysis , Microscopy, Energy-Filtering Transmission Electron/*methods, Animals ; Astrocytes/ultrastructure ; Cell-Penetrating Peptides/analysis ; Cells, Cultured ; Dogs ; HEK293 Cells ; Hippocampus/cytology ; Humans ; Madin Darby Canine Kidney Cells ; Male ; Mice, Inbred BALB C

المؤلفون: Butko MT; Biodesy, Inc. , 384 Oyster Point Boulevard, Suite No. 8, South San Francisco, California 94080, United States., Moree B; Biodesy, Inc. , 384 Oyster Point Boulevard, Suite No. 8, South San Francisco, California 94080, United States., Mortensen RB; Biodesy, Inc. , 384 Oyster Point Boulevard, Suite No. 8, South San Francisco, California 94080, United States., Salafsky J; Biodesy, Inc. , 384 Oyster Point Boulevard, Suite No. 8, South San Francisco, California 94080, United States.

المصدر: Analytical chemistry [Anal Chem] 2016 Nov 01; Vol. 88 (21), pp. 10482-10489. Date of Electronic Publication: 2016 Oct 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

مواضيع طبية MeSH: DNA/*chemistry , Intercalating Agents/*pharmacology , Lipid Bilayers/*chemistry , Oligonucleotides/*chemistry , RNA/*chemistry, Drug Evaluation, Preclinical/instrumentation ; Equipment Design ; High-Throughput Screening Assays/instrumentation ; Ligands ; Nucleic Acid Conformation

المؤلفون: Palida SF; Department of Pharmacology., Butko MT; Department of Pharmacology., Ngo JT; Department of Pharmacology, Howard Hughes Medical Institute., Mackey MR; National Center for Microscopy and Imaging Research., Gross LA; Department of Pharmacology, Howard Hughes Medical Institute., Ellisman MH; National Center for Microscopy and Imaging Research, Department of Neurosciences, and., Tsien RY; Department of Pharmacology, Howard Hughes Medical Institute, Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, California 92093 rtsien@ucsd.edu.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2015 May 20; Vol. 35 (20), pp. 7736-49.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Proteolysis*, Dendritic Spines/*metabolism , Isoenzymes/*metabolism , Protein Kinase C/*metabolism , Synapses/*metabolism, Amino Acid Sequence ; Animals ; Cells, Cultured ; Dendritic Spines/physiology ; Enzyme Stability ; HEK293 Cells ; Humans ; Isoenzymes/biosynthesis ; Isoenzymes/genetics ; Long-Term Potentiation ; Molecular Sequence Data ; Protein Kinase C/genetics ; Rats ; Rats, Sprague-Dawley ; Synapses/physiology ; Up-Regulation

المؤلفون: Butko MT; Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093, USA., Savas JN, Friedman B, Delahunty C, Ebner F, Yates JR 3rd, Tsien RY

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Feb 19; Vol. 110 (8), pp. E726-35. Date of Electronic Publication: 2013 Feb 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Proteomics* , Sensory Deprivation* , Synapses*, Nerve Tissue Proteins/*metabolism, Animals ; Immunohistochemistry ; Mice ; Microscopy, Electron ; Tandem Mass Spectrometry

المؤلفون: Butko MT; Department of Pharmacology and Howard Hughes Medical Institute, University of California San Diego, La Jolla, California, USA., Yang J, Geng Y, Kim HJ, Jeon NL, Shu X, Mackey MR, Ellisman MH, Tsien RY, Lin MZ

المصدر: Nature neuroscience [Nat Neurosci] 2012 Dec; Vol. 15 (12), pp. 1742-51. Date of Electronic Publication: 2012 Oct 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Fluorescent Dyes*, Bacterial Proteins/*analysis , Intracellular Signaling Peptides and Proteins/*metabolism , Luminescent Proteins/*analysis , Membrane Proteins/*metabolism , Membrane Proteins/*ultrastructure, Animals ; Animals, Newborn ; Bacterial Proteins/ultrastructure ; Cells, Cultured ; Disks Large Homolog 4 Protein ; Epitopes/analysis ; Epitopes/ultrastructure ; HEK293 Cells ; Humans ; Luminescent Proteins/ultrastructure ; Microscopy, Electron/methods ; Microscopy, Fluorescence/methods ; Rats ; Rats, Sprague-Dawley ; Time Factors

المؤلفون: Butko MT; Department of Neuroscience and Biomedical Graduate Program, Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093, USA., Drobizhev M, Makarov NS, Rebane A, Brinkman BC, Gleeson JG

المصدر: BMC biotechnology [BMC Biotechnol] 2011 Mar 02; Vol. 11, pp. 20. Date of Electronic Publication: 2011 Mar 02.

نوع المنشور: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101088663 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6750 (Electronic) Linking ISSN: 14726750 NLM ISO Abbreviation: BMC Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Microscopy, Fluorescence, Multiphoton/*methods, Animals ; Cell Line ; Cells/metabolism ; Humans ; Sensitivity and Specificity