نتائج البحث - "Butyrates pharmacology"

1

Involvement of the tumor suppressor gene p53 in tumor necrosis factor-induced differentiation of the leukemic cell line K562

المؤلفون: Ehinger, Mats, Nilsson, Eva, Persson, Ann-Maj, Olsson, Inge, Gullberg, Urban

المصدر: Cell Growth and Differentiation. 6(1):9-17

مصطلحات موضوعية: Antibodies, Monoclonal/immunology, Apoptosis, Base Sequence, Butyrates/pharmacology, Butyric Acid, Cell Differentiation, Cell Division/drug effects, Gene Expression/genetics, Genes, p53/genetics, Hemoglobins/biosynthesis, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology, Molecular Sequence Data, Transfection/genetics, Tretinoin/pharmacology, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha/pharmacology, Tumor Suppressor Protein p53/biosynthesis, Medicin och hälsovetenskap, Klinisk medicin, Hematologi, Medical and Health Sciences, Clinical Medicine, Hematology, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi, Basic Medicine, Cell and Molecular Biology, Cancer och onkologi, Cancer and Oncology

URL الوصول: https://lup.lub.lu.se/record/ea22339a-64d7-47d4-9a1c-2e2c751e6aab
http://cgd.aacrjournals.org/cgi/reprint/6/1/9

2

Development of a self-limiting model of methotrexate-induced mucositis reinforces butyrate as a potential therapy

المؤلفون: da Silva Ferreira, A R, van der Aa, S A J, Wehkamp, T, Wardill, H R, Ten Klooster, J P, Garssen, J, Harthoorn, L F, Hartog, A, Harmsen, H J M, Tissing, W J E, van Bergenhenegouwen, J, Afd Pharmacology, Pharmacology

المساهمون: Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Microbes in Health and Disease (MHD), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Afd Pharmacology, Pharmacology

المصدر: Scientific Reports, 11(1), 1. NLM (Medline)
Scientific Reports
Scientific Reports, 11:22911. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific reports

مصطلحات موضوعية: Antimetabolites, medicine.medical_treatment, Leucovorin, Pharmacology, Inbred C57BL, Tissue Culture Techniques, chemistry.chemical_compound, Mice, Citrulline, Ileum/drug effects, Intestinal Mucosa, Multidisciplinary, Antineoplastic/toxicity, Citrulline/metabolism, Intestinal stem cells, Cytokines/metabolism, Organoids, Butyrates, Cytokine, Leucovorin/pharmacology, Toxicity, Medicine, Cytokines, Antimetabolites, Antineoplastic/toxicity, Female, medicine.drug, Mucositis, Antimetabolites, Antineoplastic, Intestinal Mucosa/drug effects, Science, Butyrate, Article, Folinic acid, Methotrexate/toxicity, Ileum, Organoid, medicine, Butyrates/pharmacology, Chemotherapy, Animals, business.industry, medicine.disease, Mice, Inbred C57BL, Methotrexate, chemistry, Mucositis/chemically induced, Microbiome, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f0be1bb49864df41a96eba18f87645
https://dspace.library.uu.nl/handle/1874/419704

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3

Sodium Butyrate Stimulates Expression of Fibroblast Growth Factor 21 in Liver by Inhibition of Histone Deacetylase 3

المؤلفون: Jin Zhang, Zhanguo Gao, Weiping Jia, Aimin Xu, Huating Li, Xin Ye, Jianping Ye

المصدر: Diabetes

مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Mice, Obese, Mice, chemistry.chemical_compound, 0302 clinical medicine, Ketogenesis, Promoter Regions, Genetic, Hypolipidemic Agents, Mice, Knockout, chemistry.chemical_classification, 0303 health sciences, Sodium butyrate, Hep G2 Cells, 3. Good health, Butyrates, Liver, Ketone bodies, medicine.drug, Fibroblast Growth Factors - genetics - metabolism, medicine.medical_specialty, 030209 endocrinology & metabolism, Butyrate, Butyrates - pharmacology, Biology, Histone Deacetylases, 03 medical and health sciences, Internal medicine, Internal Medicine, medicine, Animals, Humans, Gene Expression Regulation - drug effects - physiology, PPAR alpha, Obesity, RNA, Messenger, 030304 developmental biology, Fatty acid, Histone Deacetylases - metabolism, HDAC3, Dietary Fats, Fibroblast Growth Factors, HEK293 Cells, Metabolism, Trichostatin A, Endocrinology, Gene Expression Regulation, chemistry, Histone deacetylase, Bezafibrate, Bezafibrate - pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6611769b8da3912c3cf406adfaff4de
https://doi.org/10.2337/db11-0846

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4

Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes

المؤلفون: Rada-Iglesias, Alvaro, Enroth, Stefan, Ameur, Adam, Koch, Christoph M., Clelland, Gayle K., Respuela-Alonso, Patricia, Wilcox, Sarah, Dovey, Oliver M., Ellis, Peter D., Langford, Cordelia F., Dunham, Ian, Komorowski, Jan, Wadelius, Claes

المصدر: Genome Research. 17(6):708-719

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-17397
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17567991&dopt=Citation

5

Fluorescent proteins in animal cells for process development: Optimization of sodium butyrate treatment as an example

المؤلفون: Florian M. Wurm, Martin Jordan, Pascal Batard, L. Hunt

المصدر: Biotechnology and Bioengineering. 77:528-537

مصطلحات موضوعية: Luminescent Proteins/*genetics/metabolism, Cell Culture Techniques/*methods, Green Fluorescent Proteins, Cell Culture Techniques, Clone (cell biology), Gene Expression, Cell Count, Bioengineering, CHO Cells, Butyrate, Biology, Fluorescence/*methods, Applied Microbiology and Biotechnology, Green fluorescent protein, Flow cytometry, Dose-Response Relationship, chemistry.chemical_compound, Cricetinae, medicine, Animals, Glucose/metabolism, Transgenes, Recombinant Proteins/genetics/metabolism, CHO Cells/cytology/physiology, Microscopy, Dose-Response Relationship, Drug, medicine.diagnostic_test, Chinese hamster ovary cell, Sodium butyrate, Recombinant Proteins, Butyrates, Luminescent Proteins, Glucose, Microscopy, Fluorescence, Biochemistry, chemistry, Cell culture, Indicators and Reagents, Drug, Butyrates/*pharmacology, Plate reader, Indicators and Reagents/*metabolism, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c9a0f09fa4c0209435875ce432c20a
https://doi.org/10.1002/bit.10108

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6

Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor

المؤلفون: Graeme Milligan, Sunil K. Pandey, Brian D. Hudson, Amanda E. Mackenzie, Irina G. Tikhonova, Elisabeth Christiansen, Hannah Murdoch, Maria E Due-Hansen, Trond Ulven, Anna Mette Hansen, Richard J. Ward, Rudi Marquez

المصدر: The Journal of Biological Chemistry
Hudson, B D, Due-Hansen, M E, Christiansen, E, Hansen, A M, Mackenzie, A E, Murdoch, H, Pandey, S K, Ward, R J, Marquez, R, Tikhonova, I G, Ulven, T & Milligan, G 2013, ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ', Journal of Biological Chemistry, vol. 288, no. 24, pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337
Hudson, B D, Due-Hansen, M E, Christiansen, E, Hansen, A, Mackenzie, A E, Murdoch, H, Pandey, S K, Ward, R J, Marquez, R, Tikhonova, I G, Ulven, T & Milligan, G 2013, ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ', Journal of Biological Chemistry, vol. 288, pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337

مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Amino Acid Motifs, Benzeneacetamides, 7-Helix Receptor, Plasma protein binding, Lipolysis/drug effects, Biochemistry, Mice, 0302 clinical medicine, Glucagon-Like Peptide 1/metabolism, Thiazoles/chemistry, Glucagon-Like Peptide 1, Adipocytes, Receptor, 0303 health sciences, Adipocyte, 3. Good health, Enteroendocrine Cells/metabolism, Butyrates, 030220 oncology & carcinogenesis, Free fatty acid receptor, Signal transduction, Cyclopropanes/chemistry, Guanosine 5'-O-(3-Thiotriphosphate)/metabolism, Protein Binding, Signal Transduction, Receptors, Cell Surface/agonists, Enteroendocrine Cells, Lipolysis, Allosteric regulation, Receptors, Cell Surface, Biology, G Protein-coupled Receptors (GPCRs), 03 medical and health sciences, Allosteric Regulation, Free fatty acid receptor 2, Butyrates/pharmacology, Animals, Humans, Homology modeling, Binding site, Molecular Biology, 030304 developmental biology, Binding Sites, Cell Biology, Benzeneacetamides/pharmacology, Protein Structure, Tertiary, Rats, Thiazoles, HEK293 Cells, Amino Acid Substitution, Guanosine 5'-O-(3-Thiotriphosphate), Mutagenesis, Site-Directed, Fatty Acid, Adipocytes/drug effects