المؤلفون: Dennis Bo Jensen, Marion Kadlecova, Ilary Allodi, C. F. Meehan

المصدر: The Journal of Physiology. 598:4385-4403

مصطلحات موضوعية: Male, 0301 basic medicine, Adult male, Physiology, medicine.drug_class, animal diseases, Transgene, SOD1, Mice, Transgenic, Mice, 03 medical and health sciences, Superoxide Dismutase-1, 0302 clinical medicine, In vivo, medicine, Animals, Amyotrophic lateral sclerosis, Motor Neurons, Superoxide Dismutase, business.industry, Amyotrophic Lateral Sclerosis, nutritional and metabolic diseases, medicine.disease, In vitro, nervous system diseases, Disease Models, Animal, 030104 developmental biology, Rheobase, Spinal Cord, nervous system, Barbiturate, business, Neuroscience, 030217 neurology & neurosurgery, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d953e18d4fbea3453e58b009e4e114
https://doi.org/10.1113/jp280097

المؤلفون: Jacob Wienecke, Dennis Bo Jensen, C. F. Meehan, K. P. Dimintiyanova, S. Klingenberg

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Jensen, D B, Klingenberg, S, Dimintiyanova, K P, Wienecke, J & Meehan, C F 2020, ' Intramuscular Botulinum toxin A injections induce central changes to axon initial segments and cholinergic boutons on spinal motoneurones in rats ', Scientific Reports, vol. 10, no. 1, 893 . https://doi.org/10.1038/s41598-020-57699-z
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Cholera Toxin, Vesicular Acetylcholine Transport Proteins, lcsh:Medicine, Biology, medicine.disease_cause, Injections, Intramuscular, Article, 03 medical and health sciences, Gastrocnemius muscle, 0302 clinical medicine, Internal medicine, Vesicular acetylcholine transporter, medicine, Animals, Botulinum Toxins, Type A, Rats, Wistar, Muscle, Skeletal, lcsh:Science, Axon Initial Segment, Motor Neurons, Multidisciplinary, Toxin, lcsh:R, Axon initial segment, Botulinum toxin, Cholinergic Neurons, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Rheobase, Spinal Cord, Neurology, nervous system, Cholinergic, Soma, lcsh:Q, 030217 neurology & neurosurgery, medicine.drug, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaa73b34413e00a256f786b43d337ce
http://link.springer.com/article/10.1038/s41598-020-57699-z

المؤلفون: Dennis Bo Jensen, C. F. Meehan, Marion Kadlecova, Ilary Allodi

المصدر: The Journal of physiologyReferences. 599(17)

مصطلحات موضوعية: Physiology, Philosophy, MEDLINE, Library science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ee26fe72142360692c834728c739a0
https://pubmed.ncbi.nlm.nih.gov/34192811

المؤلفون: Dennis Bo Jensen, Natalya Sukiasyan, Anne Hedegaard, Hans Hultborn, C. F. Meehan, Katinka Stecina, Jacob Wienecke

المصدر: The Journal of Neuroscience. 38:9741-9753

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.drug_class, Rate modulation, Mice, 03 medical and health sciences, 0302 clinical medicine, Species Specificity, Motor system, medicine, Animals, Muscle, Skeletal, Research Articles, Motor Neurons, Membrane potential, CATS, Chemistry, General Neuroscience, Motor control, Mixed mode, Electric Stimulation, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Spinal Cord, nervous system, Barbiturate, Cats, Biophysics, Female, Soma, 030217 neurology & neurosurgery, Muscle Contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7fe51774a76e1d042448a6f0d19a83
https://doi.org/10.1523/jneurosci.2898-17.2018

المؤلفون: J Lehnhoff, Mihai Moldovan, Anne Hedegaard, Henriette S Jørgensen, Dennis Bo Jensen, Lillian Grøndahl, K. P. Dimintiyanova, C. F. Meehan, V.S. Bonnevie

المصدر: Jørgensen, H S, Jensen, D B, Dimintiyanova, K P, Bonnevie, V S, Hedegaard, A, Lehnhoff, J, Moldovan, M, Grondahl, L & Meehan, C F 2021, ' Increased Axon Initial Segment Length Results in Increased Na+ Currents in Spinal Motoneurones at Symptom Onset in the G127X SOD1 Mouse Model of Amyotrophic Lateral Sclerosis ', Neuroscience, vol. 468, pp. 247-264 . https://doi.org/10.1016/j.neuroscience.2020.11.016

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, medicine.medical_specialty, SOD1, EXCITABILITY CHANGES, LUMBAR MOTONEURONS, ASTROCYTES, axon initial segment, 03 medical and health sciences, 0302 clinical medicine, MOTOR UNIT LOSS, In vivo, Internal medicine, ACTIVITY-DEPENDENT RELOCATION, medicine, Amyotrophic lateral sclerosis, Na+ channels, business.industry, General Neuroscience, nutritional and metabolic diseases, ELECTRICAL-PROPERTIES, medicine.disease, Axon initial segment, Antidromic, 030104 developmental biology, Endocrinology, SYNAPTIC-TRANSMISSION, nervous system, CORD-INJURY, TIME-COURSE, RILUZOLE, Immunohistochemistry, ALS, business, 030217 neurology & neurosurgery, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbfff9cd08b2f8bca38e79e30b2c8f2
https://curis.ku.dk/portal/da/publications/increased-axon-initial-segment-length-results-in-increased-na-currents-in-spinal-motoneurones-at-symptom-onset-in-the-g127x-sod1-mouse-model-of-amyotrophic-lateral-sclerosis(b9eefe46-013e-4580-bd24-128d3bfef7c0).html

المؤلفون: C. F. Meehan, V.S. Bonnevie, Mihai Moldovan, Henriette S Jørgensen, Dennis Bo Jensen, Lillian Grøndahl, J Lehnhoff, Anne Hedegaard, K. P. Dimintiyanova

مصطلحات موضوعية: Genetically modified mouse, medicine.medical_specialty, business.industry, SOD1, medicine.disease, Axon initial segment, Antidromic, Endocrinology, nervous system, In vivo, Internal medicine, medicine, Immunohistochemistry, Amyotrophic lateral sclerosis, business, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::566e0b62d0da7367c539e4301ba384e0
https://doi.org/10.1101/2020.06.25.096552

المؤلفون: H S, Jørgensen, D B, Jensen, K P, Dimintiyanova, V S, Bonnevie, A, Hedegaard, J, Lehnhoff, M, Moldovan, L, Grondahl, C F, Meehan

المصدر: Neuroscience. 468

مصطلحات موضوعية: Disease Models, Animal, Mice, Superoxide Dismutase-1, Spinal Cord, Superoxide Dismutase, Amyotrophic Lateral Sclerosis, Animals, Mice, Transgenic, Neurodegenerative Diseases, Axon Initial Segment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ac20183a89d1d1bb54bc069a7946f53e
https://pubmed.ncbi.nlm.nih.gov/33246068

المؤلفون: Simon Erlendsson, Gith Noes-Holt, Kathrine L. Jensen, Sofie E Pedersen, Ulrik Gether, Lise Arleth, Søren Roi Midtgaard, Klaus B. Nissen, Kenneth L. Madsen, Mette Rathje, Nikolaj R. Christensen, Kristian Strømgaard, Christian Bjerggaard Vaegter, Marta De Luca, Mette Richner, Anders Bach, Dennis Bo Jensen, Andreas T. Sørensen, Michèle Schönauer, Ina Ammendrup-Johnsen, C. F. Meehan, Michael Brett Lever, Astrid B Hansen, Kaare Teilum, Christian R. O. Bartling

المصدر: Christensen, N R, De Luca, M, Lever, M B, Richner, M, Hansen, A B, Noes-Holt, G, Jensen, K L, Rathje, M, Jensen, D B, Erlendsson, S, Bartling, C R, Ammendrup-Johnsen, I, Pedersen, S E, Schönauer, M, Nissen, K B, Midtgaard, S R, Teilum, K, Arleth, L, Sørensen, A T, Bach, A, Strømgaard, K, Meehan, C F, Vaegter, C B, Gether, U & Madsen, K L 2020, ' A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain ', EMBO Molecular Medicine, vol. 12, 11248 . https://doi.org/10.15252/emmm.201911248
Christensen, N R, De Luca, M, Lever, M B, Richner, M, Hansen, A B, Noes-Holt, G, Jensen, K L, Rathje, M, Jensen, D B, Erlendsson, S, Bartling, C R O, Ammendrup-Johnsen, I, Pedersen, S E, Schönauer, M, Nissen, K B, Midtgaard, S R, Teilum, K, Arleth, L, Sørensen, A T, Bach, A, Strømgaard, K, Meehan, C F, Vægter, C B, Gether, U & Madsen, K L 2020, ' A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain ', EMBO Molecular Medicine, vol. 12, no. 6, e11248 . https://doi.org/10.15252/emmm.201911248
EMBO molecular medicine 12(6), e11248 (2020). doi:10.15252/emmm.201911248
EMBO Molecular Medicine, Vol 12, Iss 6, Pp n/a-n/a (2020)
EMBO Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Medicine (General), PDZ domain, PDZ Domains, AMPA receptor, QH426-470, Article, Cell membrane, 03 medical and health sciences, R5-920, 0302 clinical medicine, Chemical Biology, Genetics, medicine, Humans, Receptors, AMPA, ddc:610, synaptic plasticity, Chemistry, calcium permeable AMPARs, Nuclear Proteins, Articles, biopharmaceuticals, Cell biology, maladaptive plasticity, scaffold proteins, 030104 developmental biology, medicine.anatomical_structure, Membrane protein, Synaptic plasticity, Neuropathic pain, Neuralgia, Molecular Medicine, Carrier Proteins, PICK1, 030217 neurology & neurosurgery, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f2a79c35640aba4c47c10fe446bf83
https://pure.au.dk/portal/da/publications/a-highaffinity-bivalent-pdz-domain-inhibitor-complexes-pick1-to-alleviate-neuropathic-pain(1f97eff6-28ca-4b06-a6fe-7e8ac62e3100).html

المؤلفون: Mihai Moldovan, V.S. Bonnevie, Anne Hedegaard, C. F. Meehan, Lillian Grøndahl, J Lehnhoff, K. P. Dimintiyanova

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Bonnevie, V S, Dimintiyanova, K P, Hedegaard, A, Lehnhoff, J, Grøndahl, L, Moldovan, M & Meehan, C F 2020, ' Shorter axon initial segments do not cause repetitive firing impairments in the adult presymptomatic G127X SOD-1 Amyotrophic Lateral Sclerosis mouse ', Scientific Reports, vol. 10, no. 1, 1280 . https://doi.org/10.1038/s41598-019-57314-w
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, SOD1, Mutation, Missense, lcsh:Medicine, Alpha (ethology), Mice, Transgenic, Neurotransmission, Biology, Ion channels in the nervous system, Synaptic Transmission, Article, Mice, 03 medical and health sciences, Superoxide Dismutase-1, 0302 clinical medicine, medicine, Animals, Humans, Amyotrophic lateral sclerosis, lcsh:Science, Motor Neurons, Multidisciplinary, Sodium channel, Amyotrophic Lateral Sclerosis, lcsh:R, medicine.disease, Axon initial segment, Axons, Peripheral, Disease Models, Animal, 030104 developmental biology, Amino Acid Substitution, nervous system, lcsh:Q, Neuroscience, 030217 neurology & neurosurgery, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa57dacfbf0a99d160a13b5b3f0d384
https://doi.org/10.1038/s41598-019-57314-w

المؤلفون: Peter A. Kirkwood, Tim W. Ford, C. F. Meehan

المصدر: Experimental neurology. 331

مصطلحات موضوعية: 0301 basic medicine, Male, Dendritic spine, Microtubule-associated protein, Plasticity, Hyperreflexia, Biology, Thoracic Vertebrae, Lesion, 03 medical and health sciences, 0302 clinical medicine, Developmental Neuroscience, Interneurons, medicine, Animals, Axon, Spinal Cord Injuries, Neuronal Plasticity, Anatomy, Commissure, 030104 developmental biology, medicine.anatomical_structure, Neurology, Cats, Soma, Female, medicine.symptom, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7b4bd9596f49b5ae34ef3c43fcb08c
https://pubmed.ncbi.nlm.nih.gov/32464119