المؤلفون: Mariano A; Department of Biochemical Sciences, Sapienza University of Rome, Roma, Italy., Ammendola S; Ambiotec di Sergio Ammendola, Cisterna di Latina, Italy., Migliorini A; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Leopizzi M; Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino-Sapienza University, Latina, Italy., Raimondo D; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Scotto d'Abusco A; Department of Biochemical Sciences, Sapienza University of Rome, Roma, Italy.

المصدر: Cell biochemistry and function [Cell Biochem Funct] 2024 Jul; Vol. 42 (5), pp. e4091.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8305874 Publication Model: Print Cited Medium: Internet ISSN: 1099-0844 (Electronic) Linking ISSN: 02636484 NLM ISO Abbreviation: Cell Biochem Funct Subsets: MEDLINE

مواضيع طبية MeSH: RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Fibroblasts*/metabolism , Fibroblasts*/drug effects , Phospholipase C gamma*/metabolism , Phospholipase C gamma*/genetics , Introns*, Humans ; Cells, Cultured ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; Synovial Membrane/metabolism ; Synovial Membrane/cytology ; Synovial Membrane/drug effects ; Matrix Metalloproteinase 3/metabolism ; Matrix Metalloproteinase 3/genetics ; ADAMTS5 Protein/metabolism ; ADAMTS5 Protein/genetics ; Synoviocytes/metabolism ; Synoviocytes/drug effects ; Matrix Metalloproteinase 13/metabolism ; Matrix Metalloproteinase 13/genetics

المؤلفون: Hu H; Department of Cataract, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China., Nie D; Department of Cataract, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China., Fang M; Department of Glaucoma, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China., He W; Department of Cataract, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China., Zhang J; Department of Cataract, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China., Liu X; Department of Cataract, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China., Zhang G; Department of Fundus Disease, Shenzhen Eye Hospital, Shenzhen Eye Institute, Jinan University, Shenzhen, China.

المصدر: The FEBS journal [FEBS J] 2024 Jun; Vol. 291 (12), pp. 2703-2714. Date of Electronic Publication: 2024 Feb 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

مواضيع طبية MeSH: TRPV Cation Channels*/metabolism , TRPV Cation Channels*/genetics , Glaucoma*/pathology , Glaucoma*/metabolism , Glaucoma*/genetics , Ependymoglial Cells*/metabolism , Ependymoglial Cells*/pathology , Phospholipase C gamma*/metabolism , Phospholipase C gamma*/genetics , Calcium*/metabolism , Cell Survival*/genetics , Retinal Ganglion Cells*/metabolism , Retinal Ganglion Cells*/pathology , Hydrostatic Pressure*, Animals ; Mice ; Disease Models, Animal ; Mice, Inbred C57BL ; Intraocular Pressure ; Adenosine Triphosphate/metabolism ; Receptors, Purinergic P2X7/metabolism ; Receptors, Purinergic P2X7/genetics ; Male ; Apoptosis ; Cells, Cultured

المؤلفون: Wang Y; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Peng D; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Department of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China., Zhang X; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Chen J; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Feng J; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Zhang R; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Mai W; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China., Chen H; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou 510632, China; National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou 510632, China., Yang Y; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou 510632, China; National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou 510632, China., Huang Y; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou 510632, China; National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou 510632, China. Electronic address: tydhuang@jnu.edu.cn., Zhang Q; Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou 510632, China; National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou 510632, China. Electronic address: tqhzhang@jnu.edu.cn.

المصدر: Journal of hazardous materials [J Hazard Mater] 2024 Aug 05; Vol. 474, pp. 134756. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE

مواضيع طبية MeSH: Cadmium*/toxicity , Brain-Derived Neurotrophic Factor*/metabolism , Phospholipase C gamma*/metabolism , Signal Transduction*/drug effects , Cyclic AMP Response Element-Binding Protein*/metabolism , Prenatal Exposure Delayed Effects* , Hippocampus*/drug effects , Hippocampus*/metabolism , Lactation* , Cognitive Dysfunction*/chemically induced, Animals ; Female ; Male ; Pregnancy ; Phospholipase C beta/metabolism ; Rats, Sprague-Dawley ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; Maternal Exposure ; Rats

المؤلفون: Zhu Z; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Luo Y; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Liao H; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Guo R; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Hao D; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Lu Z; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Huang M; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Sun C; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd., Linyi City, Shandong Province, China., Yao J; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd., Linyi City, Shandong Province, China., Wei N; Department of Oncology and Cancer Therapeutics Program, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, New York, United States., Zeng K; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China., Tu P; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China., Zhang G; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd., Linyi City, Shandong Province, China.

المصدر: Thrombosis and haemostasis [Thromb Haemost] 2024 Aug; Vol. 124 (8), pp. 753-769. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Thieme Country of Publication: Germany NLM ID: 7608063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2567-689X (Electronic) Linking ISSN: 03406245 NLM ISO Abbreviation: Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Phospholipase C gamma*/metabolism , Signal Transduction*/drug effects , Thromboxane A2*/metabolism , Platelet Activation*/drug effects , Hemostasis*/drug effects , Thrombin*/metabolism , Blood Platelets*/metabolism , Blood Platelets*/drug effects , Protein Kinase C*/metabolism , Flavonoids*/pharmacology , Platelet Aggregation*/drug effects , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism, Animals ; Mice ; Humans ; Male ; Mice, Inbred C57BL ; Hemorrhage/chemically induced ; Hemorrhage/drug therapy ; Bleeding Time

المؤلفون: Xie A; Department of Anesthesiology, People’s Hospital of Deyang, Deyang, Sichuan, China., Zhang X; Department of Anesthesiology, People’s Hospital of Deyang, Deyang, Sichuan, China., Ju F; Department of Anesthesiology, People’s Hospital of Deyang, Deyang, Sichuan, China., Zhou Y; Department of Anesthesiology, People’s Hospital of Deyang, Deyang, Sichuan, China., Wu D; Department of Anesthesiology, People’s Hospital of Deyang, Deyang, Sichuan, China., Han J; Department of Anesthesiology, People’s Hospital of Deyang, Deyang, Sichuan, China.

المصدر: Aging [Aging (Albany NY)] 2024 Jul 05; Vol. 16 (13), pp. 11062-11071. Date of Electronic Publication: 2024 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-4589 (Electronic) Linking ISSN: 19454589 NLM ISO Abbreviation: Aging (Albany NY) Subsets: MEDLINE

مواضيع طبية MeSH: Sevoflurane*/pharmacology , Endoplasmic Reticulum Stress*/drug effects , Neuralgia*/metabolism , Neuralgia*/drug therapy , Signal Transduction*/drug effects , Oxidative Stress*/drug effects , Calcium-Calmodulin-Dependent Protein Kinase Type 2*/metabolism , Phospholipase C gamma*/metabolism , Inositol 1,4,5-Trisphosphate Receptors*/metabolism , Endoplasmic Reticulum Chaperone BiP* , Mice, Inbred C57BL*, Animals ; Mice ; Male ; Spinal Cord/metabolism ; Spinal Cord/drug effects ; Spinal Cord/pathology ; Homeostasis/drug effects ; Disease Models, Animal ; Sciatic Nerve/drug effects ; Sciatic Nerve/metabolism ; Sciatic Nerve/injuries

المؤلفون: Wang J; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Wu X; Department of Neurology, Wushan County People's Hospital of Chongqing, Chongqing, China., Fang J; Department of Neurosurgery, Second Affiliated Hospital of Jiaxing University, Jiaxing, China. Electronic address: Fang_jc@126.com., Li Q; Chongqing Health Center for Women and Children, Chongqing, China; Women and Children's Hospital of Chongqing Medical University, Chongqing, China. Electronic address: liqian12210@sina.com.

المصدر: Experimental gerontology [Exp Gerontol] 2024 Jul; Vol. 192, pp. 112452. Date of Electronic Publication: 2024 May 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE

مواضيع طبية MeSH: Phospholipase C gamma*/metabolism , Endothelial Cells*/drug effects , Endothelial Cells*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Apoptosis*/drug effects , Signal Transduction* , Cell Hypoxia*, Animals ; Cell Proliferation/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Brain/blood supply ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Rats ; Microvessels/drug effects ; Cells, Cultured ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/physiology ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor A/pharmacology

المؤلفون: Smith CIE; Department of Laboratory Medicine, Karolinska Institutet, and Karolinska ATMP Center, ANA Futura, Huddinge, Sweden., Zain R; Department of Laboratory Medicine, Karolinska Institutet, and Karolinska ATMP Center, ANA Futura, Huddinge, Sweden.; Centre for Rare Diseases, Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.

المصدر: European journal of haematology [Eur J Haematol] 2024 Jul; Vol. 113 (1), pp. 130-131. Date of Electronic Publication: 2024 Mar 26.

نوع المنشور: Letter

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 8703985 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0609 (Electronic) Linking ISSN: 09024441 NLM ISO Abbreviation: Eur J Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Agammaglobulinaemia Tyrosine Kinase*/genetics , Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors , Gain of Function Mutation* , Phospholipase C gamma*/genetics , Protein Kinase Inhibitors*/therapeutic use, Humans ; Drug Resistance, Neoplasm/genetics ; Mutation

المؤلفون: Wang H; Department of Neurobiology, School of Basic Medical Science, Capital Medical University, Beijing 100069, PR China., Han S; Department of Neurobiology, School of Basic Medical Science, Capital Medical University, Beijing 100069, PR China., Xie J; Department of Neurobiology, School of Basic Medical Science, Capital Medical University, Beijing 100069, PR China., Zhao R; Department of Neurobiology, School of Basic Medical Science, Capital Medical University, Beijing 100069, PR China., Li S; The Neurological Department, Fu Wai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100037, PR China. Electronic address: shujuanli@ccmu.edu.cn., Li J; Department of Neurobiology, School of Basic Medical Science, Capital Medical University, Beijing 100069, PR China. Electronic address: junfali@ccmu.edu.cn.

المصدر: Experimental neurology [Exp Neurol] 2024 Sep; Vol. 379, pp. 114863. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Calpain*/metabolism , Calpain*/antagonists & inhibitors , Interleukin-17*/metabolism , Apoptosis*/physiology , Apoptosis*/drug effects , Phospholipase C gamma*/metabolism , Neurons*/metabolism , Neurons*/pathology , Neurons*/drug effects , Mice, Inbred C57BL* , Brain Ischemia*/metabolism , Brain Ischemia*/pathology , Signal Transduction*/physiology , Signal Transduction*/drug effects , Caspase 12*/metabolism, Animals ; Mice ; Male ; src-Family Kinases/metabolism ; src-Family Kinases/antagonists & inhibitors ; Infarction, Middle Cerebral Artery/pathology ; Cells, Cultured

المؤلفون: Chinen J; Division of Immunology, Allergy, and Retrovirology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, The Woodlands, Tex. Electronic address: jchinen@bcm.edu.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 May; Vol. 153 (5), pp. 1260-1261. Date of Electronic Publication: 2024 Feb 18.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't; Editorial

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Phenotype* , Phospholipase C gamma*/genetics, Humans ; Female ; Male ; Genetic Variation ; Mutation

المؤلفون: Alinger JB; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Mace EM; Departments of Pediatrics, Baylor College of Medicine, Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex; Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY., Porter JR; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Mo., Mah-Som AY; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Daugherty AL; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Li S; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Throm AA; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Pingel JT; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Saucier N; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Yao A; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Chinn IK; Departments of Pediatrics, Baylor College of Medicine, Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex; Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex., Lupski JR; Departments of Molecular and Human Genetics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex., Ehlayel M; Hamad Medical Center, Doha, Qatar., Keller M; Children's National Medical Center, Washington, DC., Bowman GR; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Mo., Cooper MA; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo., Orange JS; Departments of Pediatrics, Baylor College of Medicine, Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex; Center for Human Immunobiology, Texas Children's Hospital, Houston, Tex; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY., French AR; Division of Rheumatology, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo. Electronic address: french_a@wustl.edu.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 Jan; Vol. 153 (1), pp. 216-229. Date of Electronic Publication: 2023 Sep 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Haploinsufficiency* , Immunologic Deficiency Syndromes*/genetics , Phospholipase C gamma*/genetics, Animals ; Humans ; Mice ; Herpesviridae Infections ; Killer Cells, Natural ; Signal Transduction