المؤلفون: Davis JC; Department of Cancer Biology, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA., Waltz SE; Department of Cancer Biology, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.; Research Service, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.

المصدر: Genes [Genes (Basel)] 2024 Jul 20; Vol. 15 (7). Date of Electronic Publication: 2024 Jul 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-met*/metabolism , Proto-Oncogene Proteins c-met*/genetics , Neoplasms*/metabolism , Neoplasms*/genetics , Neoplasms*/pathology , Receptor Protein-Tyrosine Kinases*/metabolism , Receptor Protein-Tyrosine Kinases*/genetics , Glycolysis*/genetics, Humans ; Signal Transduction ; Animals ; Cholesterol/metabolism ; Cholesterol/biosynthesis ; Gene Expression Regulation, Neoplastic

المؤلفون: Barbosa-Matos C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Borges-Pereira C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Libório-Ramos S; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Fernandes R; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Oliveira M; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Mendes-Frias A; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Silvestre R; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Osório NS; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Bastos HN; Department of Pneumology, Centro Hospitalar do São João, Porto, Portugal.; i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.; Faculty of Medicine, University of Porto, Porto, Portugal., Santos RF; i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.; School of Health Sciences - Polytechnic of Porto, Porto, Portugal., Guimarães S; Department of Pathology, Centro Hospitalar Universitário de São João, Porto, Portugal., Morais A; Department of Pneumology, Centro Hospitalar do São João, Porto, Portugal., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Louvain, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Louvain, Belgium., Carvalho A; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Cunha C; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Costa S; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus Gualtar, Braga, 4710-057, Portugal. sandracosta@med.uminho.pt.; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal. sandracosta@med.uminho.pt.

المصدر: Respiratory research [Respir Res] 2024 Jun 22; Vol. 25 (1), pp. 257. Date of Electronic Publication: 2024 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE

مواضيع طبية MeSH: Mice, Inbred C57BL* , Pneumonia*/chemically induced , Pneumonia*/pathology , Pneumonia*/metabolism , Pneumonia*/immunology , Pneumonia*/genetics , Proto-Oncogene Proteins c-met*/metabolism , Proto-Oncogene Proteins c-met*/genetics , Pulmonary Fibrosis*/chemically induced , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/metabolism , Pulmonary Fibrosis*/immunology , Pulmonary Fibrosis*/genetics, Animals ; Female ; Humans ; Male ; Mice ; Bleomycin/toxicity ; Disease Models, Animal ; Lung/pathology ; Lung/metabolism ; Lung/immunology ; Mice, Knockout

المؤلفون: Jin F; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China., Lin Y; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China., Yuan W; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China., Wu S; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China., Yang M; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China., Ding S; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China; API Engineering Technology Research Center of Liaoning Province, Shenyang, Liaoning, 110036, PR China; Small Molecular Targeted Drug R&D Engineering Research Center of Liaoning Province, Shenyang, Liaoning, 110036, PR China., Liu J; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China; API Engineering Technology Research Center of Liaoning Province, Shenyang, Liaoning, 110036, PR China; Small Molecular Targeted Drug R&D Engineering Research Center of Liaoning Province, Shenyang, Liaoning, 110036, PR China. Electronic address: liuju1216@126.com., Chen Y; College of Pharmacy of Liaoning University, Shenyang, Liaoning, 110036, PR China; API Engineering Technology Research Center of Liaoning Province, Shenyang, Liaoning, 110036, PR China; Small Molecular Targeted Drug R&D Engineering Research Center of Liaoning Province, Shenyang, Liaoning, 110036, PR China. Electronic address: sy-chenye@163.com.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jun 05; Vol. 272, pp. 116477. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Proto-Oncogene Proteins c-met*/metabolism , Neoplasms*/drug therapy , Neoplasms*/pathology , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/therapeutic use , Proto-Oncogene Mas*, Humans ; Structure-Activity Relationship ; Molecular Structure ; Cell Proliferation/drug effects ; Animals

المؤلفون: Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Nakazawa S; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Harada G; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York., Lee JK; Foundation Medicine, Cambridge, Massachusetts., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Barrichello A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Vaz VR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Lamberti G; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gandhi MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gazgalis D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Feng WW; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Jiang J; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Baldacci S; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Locquet MA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gottlieb FH; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Chen MF; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York., Lee E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Haradon D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Smokovich A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Voligny E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Nguyen T; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Goel VK; Turning Point Therapeutics, Bristol Myers Squibb Company, San Diego, California., Zimmerman Z; Turning Point Therapeutics, Bristol Myers Squibb Company, San Diego, California., Atwal S; Turning Point Therapeutics, Bristol Myers Squibb Company, San Diego, California., Wang X; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Bahcall M; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Heist RS; Massachusetts General Hospital, Boston, Massachusetts., Iqbal S; The Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Gandhi N; Caris Life Sciences, Phoenix, Arizona., Elliott A; Caris Life Sciences, Phoenix, Arizona., Vanderwalde AM; Caris Life Sciences, Phoenix, Arizona., Ma PC; Penn State Cancer Institute, Penn State College of Medicine, Penn State University, Hershey, Pennsylvania., Halmos B; Montefiore Einstein Cancer Center, Bronx, New York., Liu SV; Georgetown University, Washington, DC., Che J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Schrock AB; Foundation Medicine, Cambridge, Massachusetts., Drilon A; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York., Jänne PA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

المصدر: Cancer discovery [Cancer Discov] 2024 Aug 02; Vol. 14 (8), pp. 1440-1456.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-met*/genetics , Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Lung Neoplasms*/genetics , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Protein Kinase Inhibitors*/therapeutic use , Protein Kinase Inhibitors*/pharmacology , Point Mutation*, Humans ; Animals ; Mice ; Cell Line, Tumor

المؤلفون: Kron A; Lung Cancer Group Cologne, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany. Electronic address: anna.kron@uk-koeln.de., Scheffler M; Lung Cancer Group Cologne, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany., Wiesweg M; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany., Hummel HD; Translational Oncology/Early Clinical Trial Unit (ECTU), Comprehensive Cancer Center Mainfranken and Bavarian Cancer Research Center (BZKF), University Hospital Würzburg, Würzburg, Germany., Kulhavy J; Translational Oncology/Early Clinical Trial Unit (ECTU), Comprehensive Cancer Center Mainfranken and Bavarian Cancer Research Center (BZKF), University Hospital Würzburg, Würzburg, Germany., Gatteloehner S; Department of Pathology, University Hospital Giessen and Marburg, Giessen, Germany., Kollmeier J; Department of Pneumology, Heckeshorn Lung Clinic, Helios Klinikum Emil von Behring, Berlin, Germany., Schubart C; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Groß T; Department of Medical Oncology and Pneumology (Internal Medicine VIII), Eberhard Karls University, Tübingen, Germany., Demes MC; Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt, Germany., Keymel S; Department of Cardiology, Pulmonology, and Vascular Medicine, University Hospital Düsseldorf, Medical Faculty of the Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Joosten M; Institute of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Merkelbach-Bruse S; Institute of Pathology, University Hospital and Medical Faculty, University of Cologne, Cologne, Germany., Wölwer CB; Institute of Pathology, University Hospital and Medical Faculty, University of Cologne, Cologne, Germany., Tufman A; Department of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center, Member of the German Center for Lung Research (DZL), Munich, Germany., Kauffmann-Guerrero D; Department of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center, Member of the German Center for Lung Research (DZL), Munich, Germany., Oeser K; Novartis Pharma GmbH, Nuernberg, Germany., Zehaczek M; Novartis Pharma GmbH, Nuernberg, Germany., Jeratsch U; Novartis Pharma GmbH, Nuernberg, Germany., Wolf J; Lung Cancer Group Cologne, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.

المصدر: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2024 Aug; Vol. 207, pp. 114158. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article; Comparative Study; Multicenter Study

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Mutation* , Benzamides*/therapeutic use , Proto-Oncogene Proteins c-met*/genetics , Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Triazines*/therapeutic use , Triazines*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Aged ; Germany ; Retrospective Studies ; Adult ; Aged, 80 and over ; Protein Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/adverse effects ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/adverse effects ; Imidazoles

المؤلفون: Maleki F; Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, 53714-161, Tabriz, Iran., Razmi H; Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, 53714-161, Tabriz, Iran. Electronic address: mh_razmi@yahoo.com., Rashidi MR; Pharmacy Faculty, Tabriz University of Medical Science, Tabriz, Iran., Yousefi M; Department of Immunology, School of Medicine, Tabriz University of Medical Science, Tabriz, Iran., Ramezani S; Faculty of Textile Engineering, Urmia University of Technology, Urmia 5716693188, Iran., Ghorbani M; Iran Polymer and Petrochemical Institute, PO Box:14965/115, Tehran, Iran. Electronic address: ghorbani.marjan65@yahoo.com.

المصدر: Biosensors & bioelectronics [Biosens Bioelectron] 2024 Aug 01; Vol. 257, pp. 116319. Date of Electronic Publication: 2024 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers, Tumor*/blood , Biosensing Techniques*/methods , Electrochemical Techniques*/methods , Nanofibers*/chemistry , Proto-Oncogene Proteins c-met*/blood, Humans ; Imidazoles ; Limit of Detection ; Metal-Organic Frameworks/chemistry ; Nanoparticles/chemistry ; Neoplasms/blood ; Zeolites/chemistry

المؤلفون: Moure CJ; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Vara B; Department of Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey., Cheng MM; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Sondey C; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Muise E; Department of Data and Genome Sciences, Merck & Co., Inc., Rahway, New Jersey., Park E; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Vela Ramirez JE; Department of Discovery Pharmaceutical Sciences, Merck & Co., Inc., Rahway, New Jersey., Su D; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., D'Souza S; Department of Discovery Oncology, Merck & Co., Inc., Rahway, New Jersey., Yan Q; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Yeung CS; Department of Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey., Zhang M; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Mansueto MS; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Linn D; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Buchanan M; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Foti R; Department of PPDM, Merck & Co., Inc., Rahway, New Jersey., DiMauro E; Department of Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey., Long B; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey., Simov V; Department of Discovery Chemistry, Merck & Co., Inc., Rahway, New Jersey., Barry ER; Department of Quantitative Biosciences, Merck & Co., Inc., Rahway, New Jersey.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Aug 01; Vol. 23 (8), pp. 1095-1108.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Hepatocyte Growth Factor*/metabolism , Transcription Factors*/metabolism , Transcription Factors*/antagonists & inhibitors , Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Proto-Oncogene Proteins c-met*/metabolism , Signal Transduction*/drug effects , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/antagonists & inhibitors , YAP-Signaling Proteins* , Drug Resistance, Neoplasm*/drug effects, Humans ; Animals ; Mice ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Small Molecule Libraries/pharmacology ; TEA Domain Transcription Factors ; Cell Proliferation/drug effects

المؤلفون: Hong G; Traumatology & Orthopedics Institute, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, P.R. China.; Department of Orthopedic, the Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, P.R. China.; Division of Orthopaedic Surgery, University of Alberta, Edmonton, Alberta, Canada., Xie W; Developmental and Stem Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Ahmed K; Developmental and Stem Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Oborn C; Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada., Soltys CL; Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada., Kannu P; Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jul 31; Vol. 38 (14), pp. e23810.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Osteogenesis*/genetics , Proto-Oncogene Proteins c-met*/genetics , Proto-Oncogene Proteins c-met*/metabolism , Fracture Healing*/genetics , Bone Diseases, Developmental*/genetics , Bone Diseases, Developmental*/pathology , Disease Models, Animal* , Fibrous Dysplasia of Bone*/genetics , Fibrous Dysplasia of Bone*/pathology , Fibrous Dysplasia of Bone*/metabolism, Animals ; Mice ; Humans ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Mutation ; Cell Differentiation ; Mice, Inbred C57BL ; Male

SCR Disease Name: Osteofibrous Dysplasia

المؤلفون: Chiawpanit C; Cell Engineering for Cancer Therapy Research Group, Chiang Mai University, Chiang Mai, Thailand; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand; Office of Research Administration, Chiang Mai University, Chiang Mai, Thailand., Wathikthinnakorn M; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sawasdee N; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Phanthaphol N; College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom., Sujjitjoon J; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Junking M; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Yamabhai M; Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agriculture Technology, Suranaree University of Technology, Nakhon Ratchasima, Thailand., Panaampon J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Yenchitsomanus PT; Siriraj Center of Research Excellence for Cancer Immunotherapy (SiCORE-CIT), Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Panya A; Cell Engineering for Cancer Therapy Research Group, Chiang Mai University, Chiang Mai, Thailand; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand. Electronic address: aussara.pan@cmu.ac.th.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Jul 30; Vol. 136, pp. 112273. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Single-Chain Antibodies*/genetics , Single-Chain Antibodies*/therapeutic use , Single-Chain Antibodies*/immunology , Cholangiocarcinoma*/therapy , Cholangiocarcinoma*/immunology , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Killer Cells, Natural*/immunology , Bile Duct Neoplasms*/therapy , Bile Duct Neoplasms*/immunology , Proto-Oncogene Proteins c-met*/metabolism , Proto-Oncogene Proteins c-met*/immunology, Humans ; Cell Line, Tumor ; Immunotherapy, Adoptive/methods ; Immunotherapy/methods ; Precision Medicine

المؤلفون: Min W; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Yang H; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Wang D; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Chen C; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Wang Y; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Hou Y; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Zhu Y; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Sun C; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Wang X; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Yuan K; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China., Yang P; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 211198, China.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 12314-12330. Date of Electronic Publication: 2024 Jul 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Proto-Oncogene Proteins c-met*/metabolism , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Liver Neoplasms*/drug therapy , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/therapeutic use, Humans ; Cell Line, Tumor ; Structure-Activity Relationship ; Animals ; Cell Proliferation/drug effects ; Drug Discovery ; Proteolysis/drug effects ; Drug Screening Assays, Antitumor ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/therapeutic use ; Mice