نتائج البحث - "C. Storgard"

1

Lesinurad monotherapy in gout patients intolerant to a xanthine oxidase inhibitor: a 6 month phase 3 clinical trial and extension study

المؤلفون: Maple Fung, J. Kopicko, C. Storgard, Kenneth G. Saag, Nihar Bhakta, Anne-Kathrin Tausche, Scott Baumgartner, Rieke Alten, Scott Adler, Nicola Dalbeth

المصدر: Rheumatology. 56:2170-2178

مصطلحات موضوعية: Adult, Male, Xanthine Oxidase, medicine.medical_specialty, Adolescent, Gout, medicine.drug_class, Drug Resistance, Pharmacology, Placebo, Gastroenterology, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Double-Blind Method, Rheumatology, Internal medicine, medicine, Clinical endpoint, Humans, Pharmacology (medical), 030212 general & internal medicine, Enzyme Inhibitors, Adverse effect, Xanthine oxidase inhibitor, Contraindication, Aged, Aged, 80 and over, 030203 arthritis & rheumatology, business.industry, Lesinurad, Middle Aged, Triazoles, Uricosuric Agents, medicine.disease, Treatment Outcome, chemistry, Thioglycolates, Uric acid, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f259315042f81c571e50f1d570fc53e
https://doi.org/10.1093/rheumatology/kex350

2

Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial

المؤلفون: Fernando Perez-Ruiz, Dinesh Khanna, Graeme Jones, J. Kopicko, Scott Adler, Nicola Dalbeth, Maple Fung, C. Storgard, Robert Terkeltaub, Nihar Bhakta, Scott Baumgartner

المصدر: Arthritis & Rheumatology. 69:1903-1913

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2816effc2326508d1ef93329e8667386
https://doi.org/10.1002/art.40159

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3

Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study)

المؤلفون: Nihar Bhakta, Robert T. Keenan, Scott Baumgartner, Alexander So, C. Storgard, Thomas Bardin, Puja P. Khanna, Scott Adler, J. Kopicko, Maple Fung

المصدر: Annals of the Rheumatic Diseases
Annals of the rheumatic diseases, vol. 76, no. 5, pp. 811-820

مصطلحات موضوعية: Male, Gout, Placebo-controlled study, chemistry.chemical_compound, 0302 clinical medicine, Clinical endpoint, Immunology and Allergy, Medicine, 030212 general & internal medicine, Renal Insufficiency, Young adult, Aged, 80 and over, Lesinurad, Middle Aged, Uricosuric Agents, Symptom Flare Up, Cardiovascular Diseases, Outcomes research, Creatinine, Thioglycolates, Retreatment, Drug Therapy, Combination, Female, medicine.drug, Adult, musculoskeletal diseases, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Allopurinol, Immunology, General Biochemistry, Genetics and Molecular Biology, Gout Suppressants, 03 medical and health sciences, Young Adult, Pharmacotherapy, Rheumatology, Double-Blind Method, Internal medicine, Humans, Aged, 030203 arthritis & rheumatology, Inflammation, business.industry, nutritional and metabolic diseases, Triazoles, Clinical and Epidemiological Research, medicine.disease, Surgery, Uric Acid, chemistry, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2c8d9bdf7dc5422a447f3e29149880
http://europepmc.org/articles/PMC5530336

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4

Comorbidity Burden in Trial-Aligned Patients with Established Gout in Germany, UK, US, and France: a Retrospective Analysis

المؤلفون: R. Morlock, Laura Horne, Pierre Chevalier, Dionne M. Hines, Xavier Ansolabehere, Lalitha Aiyer, C. Storgard, Fredrik Nyberg, Javier Nuevo

المصدر: Advances in Therapy

مصطلحات موضوعية: Male, Pediatrics, Gout, Databases, Factual, Myocardial Infarction, Cardiovascular, Comorbidities, 0302 clinical medicine, Serum uric acid, Germany, Retrospective analysis, Prevalence, Pharmacology (medical), 030212 general & internal medicine, Renal, media_common, Original Research, Medicine(all), Incidence (epidemiology), Incidence, General Medicine, Middle Aged, Cardiovascular Diseases, Female, Kidney Diseases, France, musculoskeletal diseases, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Pharmacology toxicology, 03 medical and health sciences, medicine, media_common.cataloged_instance, Humans, European Union, European union, Aged, Retrospective Studies, 030203 arthritis & rheumatology, business.industry, nutritional and metabolic diseases, Retrospective cohort study, medicine.disease, Comorbidity, United States, United Kingdom, Physical therapy, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8a678e0bd6479ecb86213b7b6e93e9
http://europepmc.org/articles/PMC4939171

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5

Lesinurad in combination with allopurinol: results of a phase 2, randomised, double-blind study in patients with gout with an inadequate response to allopurinol

المؤلفون: Fernando Perez-Ruiz, C. Storgard, Jeffrey N. Miner, M. Cravets, John S. Sundy

المصدر: Annals of the Rheumatic Diseases

مصطلحات موضوعية: musculoskeletal diseases, Adult, Male, medicine.medical_specialty, Gout, Allopurinol, Immunology, Urology, Placebo, General Biochemistry, Genetics and Molecular Biology, Gout Suppressants, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacotherapy, Double-Blind Method, Rheumatology, medicine, Clinical endpoint, Humans, Immunology and Allergy, Pharmacokinetics, 030212 general & internal medicine, Inflammation, 030203 arthritis & rheumatology, business.industry, nutritional and metabolic diseases, Lesinurad, Clinical and Epidemiological Research, Middle Aged, Triazoles, medicine.disease, Surgery, Treatment, Treatment Outcome, chemistry, Tolerability, Thioglycolates, Uric acid, Drug Therapy, Combination, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facd994bbac836170aa40a29ddfc6610
https://doi.org/10.1136/annrheumdis-2015-207919

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6

Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males

المؤلفون: Colin Edward Rowlings, Vijay Hingorani, Kimberly Manhard, C. Storgard, Zancong Shen, Brad Kerr, Li-Tain Yeh, Barry D. Quart

المصدر: Drug Design, Development and Therapy

مصطلحات موضوعية: Adult, Male, Adolescent, Organic Cation Transport Proteins, Pharmaceutical Science, Administration, Oral, Biological Availability, Organic Anion Transporters, urinary excretion, Capsules, clearance, Pharmacology, chemistry.chemical_compound, Young Adult, Pharmacokinetics, Double-Blind Method, Uricosuric Agent, Drug Discovery, medicine, food effect, Humans, single and multiple doses, Dosing, urate lowering, Original Research, Drug Design, Development and Therapy, Cross-Over Studies, Lesinurad, Triazoles, Uricosuric Agents, medicine.disease, Crossover study, Healthy Volunteers, Gout, Uric Acid, Pharmaceutical Solutions, Renal Elimination, chemistry, Gastrointestinal Absorption, Pharmacodynamics, Thioglycolates, Uric acid, URAT1

وصف الملف: text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc99c7830ed003b252867a2a1d299df
http://europepmc.org/articles/PMC4494180

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7

Open-label, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of intravenously administered CNF1010 (17-(allylamino)-17-demethoxygeldanamycin [17-AAG]) in patients with solid tumors

المؤلفون: C. Storgard, D. Toft, D. D. Von Hoff, Tomislav Dragovich, David S. Mendelson, Charles Erlichman, Francis Burrows, Muhammad Wasif Saif

المصدر: Cancer Chemotherapy and Pharmacology. 71:1345-1355

مصطلحات موضوعية: Adult, Male, Drug, Cancer Research, Maximum Tolerated Dose, Receptor, ErbB-2, Lactams, Macrocyclic, media_common.quotation_subject, Antineoplastic Agents, Pharmacology, Toxicology, Pharmacokinetics, Neoplasms, Benzoquinones, polycyclic compounds, Humans, Medicine, HSP70 Heat-Shock Proteins, Pharmacology (medical), In patient, HSP90 Heat-Shock Proteins, Infusions, Intravenous, Receptor, Aged, media_common, Dose-Response Relationship, Drug, biology, business.industry, Ansamycin, Middle Aged, Hsp90, female genital diseases and pregnancy complications, Hsp70, Clinical trial, Oncology, Leukocytes, Mononuclear, biology.protein, Nanoparticles, Emulsions, Female, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93f95c30aefa50ccf7b2275aed178da
https://doi.org/10.1007/s00280-013-2134-9

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8

Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study)

المؤلفون: J. Kopicko, Kenneth G. Saag, Nihar Bhakta, Scott Adler, Michael Becker, Scott Baumgartner, C. Storgard, David Fitz-Patrick, Maple Fung

المصدر: Arthritisrheumatology (Hoboken, N.J.). 69(1)

مصطلحات موضوعية: musculoskeletal diseases, Adult, Male, medicine.medical_specialty, Adolescent, Gout, medicine.drug_class, Allopurinol, Immunology, Urology, 030204 cardiovascular system & hematology, Placebo, Gout Suppressants, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Rheumatology, Double-Blind Method, medicine, Immunology and Allergy, Humans, Xanthine oxidase inhibitor, Aged, 030203 arthritis & rheumatology, Aged, 80 and over, Creatinine, business.industry, Tophus, nutritional and metabolic diseases, Lesinurad, Middle Aged, Triazoles, Uricosuric Agents, medicine.disease, United States, Surgery, Drug Combinations, chemistry, Thioglycolates, Uric acid, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4d2da9da0cd4f9ca48d7dd3e3f0d0c
https://pubmed.ncbi.nlm.nih.gov/30134053

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9

THU0537 Clinical Response of Tophus and Flares To Extended Use of Lesinurad in Combination with A Xanthine Oxidase Inhibitor in Patients with Gout

المؤلفون: Thomas Bardin, J Hu, Nicola Dalbeth, Maple Fung, Robert Terkeltaub, C. Storgard, Fernando Perez-Ruiz

المصدر: Annals of the Rheumatic Diseases. 75:386.2-386

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c843e5639f93522c2e855fee059b8a50
https://doi.org/10.1136/annrheumdis-2016-eular.3140

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10

THU0495 Examination of Serum Uric Acid (Sua) Lowering and Safety with Extended Treatment with Lesinurad and Allopurinol in Subjects with Gout

المؤلفون: Kenneth G. Saag, J Hu, Scott Adler, Thomas Bardin, Nihar Bhakta, Michael Becker, C. Storgard, Maple Fung

المصدر: Annals of the Rheumatic Diseases. 75:371.1-371

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e6e31afb76d90abe70d04f432149754
https://doi.org/10.1136/annrheumdis-2016-eular.2727

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