نتائج البحث - "C5-convertase"

1

The Role of Properdin in C5 Convertase Activity and C5b-9 Formation in the Complement Alternative Pathway

المؤلفون: Elena B. Volokhina, Nicole C. A. J. van de Kar, Marloes A. H. M. Michels, Thea J A M van der Velden, Rianne J. F. Maas, Lambertus P. van den Heuvel

المصدر: Journal of Immunology, 207, 2465-2472
Journal of Immunology, 207, 10, pp. 2465-2472

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba78de6d5f0327c34a72846b5da0371
https://doi.org/10.4049/jimmunol.2100238

2

The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models

المؤلفون: Yi Wang, Masha Fridkis-Hareli, Ante S. Lundberg, Nirmal K. Banda, Jeff Hunter, Michael Storek, Fang Sun, Gaurav Mehta, Richard Altman, Eran Or, Suresh Katti, Krista Johnson, Tao Peng, V. Michael Holers

المصدر: Molecular Immunology. 105:150-164

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ea905eb539010676c87e74844d92dc
https://doi.org/10.1016/j.molimm.2018.09.013

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3

Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies

المؤلفون: Gregers R. Andersen, Henrik Pedersen, Nick S. Laursen, Alessandra Zarantonello

المصدر: Biomolecules
Zarantonello, A, Pedersen, H, Laursen, N S & Andersen, G R 2021, ' Nanobodies provide insight into the molecular mechanisms of the complement cascade and offer new therapeutic strategies ', Biomolecules, vol. 11, no. 2, 298 . https://doi.org/10.3390/biom11020298
Biomolecules, Vol 11, Iss 298, p 298 (2021)

مصطلحات موضوعية: 0301 basic medicine, Hemoglobinuria, Paroxysmal, Molecular Conformation, lcsh:QR1-502, Complement C3-C5 Convertases, Review, Biochemistry, lcsh:Microbiology, Epitopes, 0302 clinical medicine, proteolytic cascade, Complement C1, structural biology, Complement Activation, Convertase, Atypical Hemolytic Uremic Syndrome, Complement (complexity), inhibitor, Nanomedicine, 030220 oncology & carcinogenesis, molecular mechanism, Structural biology, Protein Binding, Complement system, Inhibitor, Proteolytic cascade, Biology, Antibodies, Monoclonal, Humanized, Molecular mechanism, C5-convertase, 03 medical and health sciences, Classical complement pathway, Atypical hemolytic uremic syndrome, medicine, biochemistry, Animals, Humans, Molecular Biology, complement system, Inflammation, Innate immune system, Complement System Proteins, Single-Domain Antibodies, medicine.disease, convertase, Immunity, Innate, 030104 developmental biology, Immunoglobulin G, Proteolysis, Paroxysmal nocturnal hemoglobinuria, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be91f65f61fa05090bd8fe2254c7d773
http://europepmc.org/articles/PMC7922070

Find this article in full text from ProQuest

4

Terminal complement without C5 convertase?

المؤلفون: Lubka T. Roumenina

المصدر: Blood. 137(4)

مصطلحات موضوعية: Terminal (electronics), Chemistry, Immunology, Complement Pathway, Alternative, Cell Biology, Hematology, Complement C3-C5 Convertases, Complement System Proteins, Longitudinal Studies, Biochemistry, Cell biology, C5-convertase, Complement (complexity)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a8c34ac4dc9d185ef9f54646b50891
https://pubmed.ncbi.nlm.nih.gov/33507296

5

Development of methods for analysis of 'C5 Nephritic Factors' (C5NeF)

المؤلفون: Bäckström, Filippa

مصطلحات موضوعية: C5 Nephritic factor, Klinisk laboratoriemedicin, Complement system, C3-glomerulopati, Komplementsystemet, C3 Nephritic factor, Clinical Laboratory Medicine, C5-konvertas, ELISA, C3-glomerulopathy, C5-convertase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______681::c4b41d23fdbb0abd501e6dd802897c19
http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-43582

6

The Role of Properdin in Killing of Non-Pathogenic Leptospira biflexa

المؤلفون: Patrícia Antonia Estima Abreu, Gurpanna Saggu, Adriana Patricia Granados Martinez, Viviana P. Ferreira, Silvio Arruda Vasconcellos, Paulo Lee Ho, Lourdes Isaac, Angela Silva Barbosa

المصدر: Frontiers in Immunology, Vol 11 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology

مصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, lcsh:Immunologic diseases. Allergy, Complement Pathway, Alternative, Immunology, alternative pathway, chemical and pharmacologic phenomena, Cell Growth Processes, PROTEÍNAS DA MEMBRANA, urologic and male genital diseases, Microbiology, law.invention, C5-convertase, 03 medical and health sciences, 0302 clinical medicine, law, Leptospira, Humans, Immunology and Allergy, Leptospirosis, bacteria killing ability, complement system, Original Research, Virulence, biology, Chemistry, biology.organism_classification, C3-convertase, female genital diseases and pregnancy complications, Complement system, properdin, 030104 developmental biology, Complement C3b, Alternative complement pathway, Recombinant DNA, Properdin, Leptospira interrogans, Bacterial outer membrane, lcsh:RC581-607, Bacterial Outer Membrane Proteins, Complement Factor B, Protein Binding, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81762969e59f479311bc64040f5998b6

7

The allosteric modulation of Complement C5 by knob domain peptides

المؤلفون: Sarah Schulze, Alastair D. G. Lawson, James Snowden, Victoria Ellis, Maisem Laabei, Sarah Robinson, Susan J. Crennell, Charlotte M. Deane, Jean M. H. van den Elsen, James R. Birtley, Dmitri I. Svergun, Ben Holmes, Vladas Oleinikovas, Tom Eirik Mollnes, Melissa A. Graewert, Per H. Nilsson, Zainab Ahdash, Alex Macpherson

مصطلحات موضوعية: chemistry.chemical_classification, Complement component 5, biology, Chemistry, viruses, Allosteric regulation, Peptide, Cleavage (embryo), C5-convertase, Cell biology, biology.protein, Alternative complement pathway, Binding site, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0967975d5e3c30a7d0fc992b18812e15
https://doi.org/10.1101/2020.10.24.353714

8

A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity

المؤلفون: Steffen Thiel, Dorte Christiansen, Beth Stevens, Gregers R. Andersen, Tom Eirik Mollnes, Neal Lojek, Nick S. Laursen, Pernille Libach Hansen, Annette G. Hansen, Trine A.F. Gadeberg, Rasmus K. Jensen, Sofia Mm Mazarakis, Matthew B. Johnson, Alessandra Zarantonello, Dennis Pedersen, Henrik Pedersen, Heidi Gytz Olesen, Rachel Fox, Jens Magnus Bernth Jensen

المصدر: Pedersen, H, Jensen, R K, Jensen, J M B, Fox, R, Pedersen, D V, Olesen, H G, Hansen, A G, Christiansen, D, Mazarakis, S M M, Lojek, N, Hansen, P, Gadeberg, T A F, Zarantonello, A, Laursen, N S, Mollnes, T E, Johnson, M B, Stevens, B, Thiel, S & Andersen, G R 2020, ' A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity ', Journal of Immunology, vol. 205, no. 8 . https://doi.org/10.4049/jimmunol.2000752

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b48ea3989418997c40a14a46a57dd73
https://pubmed.ncbi.nlm.nih.gov/32938727

9

Bacterial killing by complement requires direct anchoring of Membrane Attack Complex precursor C5b-7

المؤلفون: Suzan H.M. Rooijakkers, Maartje Ruyken, Bart W. Hoogenboom, Dennis J. Doorduijn, Bart W. Bardoel, Edward S. Parsons, Dani A. C. Heesterbeek, Georgina Benn

المصدر: PLoS Pathogens, Vol 16, Iss 6, p e1008606 (2020)
bioRxiv
Review Commons
PLoS Pathogens

مصطلحات موضوعية: Physiology, Complement System, Complement Membrane Attack Complex, medicine.disease_cause, Biochemistry, Bacterial cell structure, Spectrum Analysis Techniques, 0302 clinical medicine, Cell Wall, Animal Cells, Red Blood Cells, Immune Physiology, Medicine and Health Sciences, Biology (General), Microscopy, 0303 health sciences, Immune System Proteins, biology, Chemistry, Effector, Complement C5, Proteases, Flow Cytometry, Trypsin, Transmembrane protein, Enzymes, Atomic Force Microscopy, Spectrophotometry, Cytophotometry, Cellular Types, Research Article, medicine.drug, Blood Bactericidal Activity, Lysis (Medicine), Gram-negative bacteria, QH301-705.5, Immunology, Research and Analysis Methods, Microbiology, C5-convertase, 03 medical and health sciences, Virology, Tissue Repair, Escherichia coli, Genetics, medicine, Humans, Gram Negative Bacteria, Molecular Biology, 030304 developmental biology, Blood Cells, Bacteria, 030306 microbiology, Scanning Probe Microscopy, Cell Membrane, Organisms, Biology and Life Sciences, Proteins, Bacteriology, Complement System Proteins, Cell Biology, RC581-607, biology.organism_classification, Complement system, HEK293 Cells, Immune System, Enzymology, Biophysics, Parasitology, Serine Proteases, Immunologic diseases. Allergy, Physiological Processes, Complement membrane attack complex, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2625da39a1541480d4784d3e66115a07
https://doi.org/10.1101/2019.12.17.877639

10

Complement Component C3 Binds to the A3 Domain of von Willebrand Factor

المؤلفون: Jennifer Nolasco, Qi Da, Zaverio M. Ruggeri, Miguel A. Cruz, Leticia Nolasco, Joel L. Moake, Sonya Cirlos

المصدر: TH Open, Vol 02, Iss 03, Pp e338-e345 (2018)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f33426fb099d00fa092cb36f96dee4
https://doi.org/10.1055/s-0038-1672189

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