نتائج البحث - "CD4-Positive T-Lymphocytes: cytology"

المساهمون: Pathogénie Microbienne Moléculaire, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Biologie Cellulaire des Lymphocytes (BIOCELLY), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Régulation des Infections Rétrovirales, Institut Pasteur [Paris], Dynamique des Interactions Hôte-Pathogène - Dynamics of Host-Pathogen Interactions, Chaire Microbiologie et Maladies infectieuses, Collège de France (CdF (institution)), K.N. is a fellow from the Pasteur-Paris University International Doctoral Program. A. Puhar was supported first by EMBO long-term fellowship and is presently a Marie Curie fellow. W.S.-P. is funded by the Pasteur Foundation and the Philips Foundation. P.J.S. is a HHMI Foreign Scholar. The research leading to these results has received funding from the Institut Pasteur Transversal Research Program (PTR n° 251) and from the European Community's PEOPLE Seventh Framework Program under grant agreement EIMID IAPP - PIAP-GA-2008-217768., We warmly thank C. Parsot (Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur) for very helpful discussion, M.I. Thoulouze and A. Alcover (Unité de Biologie Cellulaire des Lymphocytes, Institut Pasteur) for sharing with us their expertise in T cells, G. Chicanne and B. Payrastre (INSERM U858, I2MR, CHU Rangueil) for their expertise in PI metabolism, and M. Arpin (Institut Curie, Paris, France) for her advice on the ERM proteins. From the G5 Dynamique des Interactions Hôte-Pathogènes, Institut Pasteur, L. Audry and A. Bobard were helpful in providing tools for the injection assay, and J. Enninga for some experimental design, discussion, and critical reading of the manuscript. T. Balla (National Institute of Child Health and Human Development, National Institutes of Health [NIH]) kindly sent PLCδ1PH-RFP construct. We also thank Benoit Marteyn for his very efficient contribution in performing Shigella infection in the rabbit ileal model and processing samples for immunohistochemistry. We are also grateful to colleagues from the IMAGOPOLE platform of the Institut Pasteur. C.K. was supported by fellowships from the European Consortium PATHOGENOMICS, the Institut Pasteur Transversal Research Program n° 251, and the Howard Hughes Medical Institute (HHMI). E.F. holds a fellowship from the European Initiative for basic research in Microbiology and Infectious Diseases (EIMID Program)., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Collège de France - Chaire Microbiologie et Maladies infectieuses

المصدر: Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2011, 9 (4), pp.263-72. ⟨10.1016/j.chom.2011.03.010⟩
Cell Host and Microbe, 2011, 9 (4), pp.263-72. ⟨10.1016/j.chom.2011.03.010⟩

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Phosphatidylinositol 4,5-Diphosphate, MESH: Bacterial Secretion Systems, MESH: CD4-Positive T-Lymphocytes / immunology, Cancer Research, MESH: Phosphatidylinositols / metabolism, Fluorescent Antibody Technique, MESH: Phosphoric Monoester Hydrolases / metabolism, Phosphatidylinositols, medicine.disease_cause, Shigella flexneri, Type three secretion system, Cell Movement, Shigella, Phosphorylation, MESH: Shigella flexneri / metabolism, Bacterial Secretion Systems, MESH: Fluorescent Antibody Technique, 0303 health sciences, biology, Effector, MESH: Bacterial Proteins / metabolism, MESH: DNA-Binding Proteins / metabolism, MESH: CD4-Positive T-Lymphocytes / cytology, DNA-Binding Proteins, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: Phosphatidylinositol 4,5-Diphosphate / deficiency, Host-Pathogen Interactions, Chemokines, Shigellosis, MESH: Chemokines / immunology, Blotting, Western, MESH: Shigella flexneri / genetics, Microbiology, Cell Line, 03 medical and health sciences, Bacterial Proteins, MESH: CD4-Positive T-Lymphocytes / metabolism, Immunology and Microbiology(all), Virology, medicine, Humans, MESH: Blotting, Western, Molecular Biology, MESH: Cell Movement / immunology, Dysentery, Bacillary, 030304 developmental biology, MESH: Transcription Factors / metabolism, MESH: Humans, MESH: Phosphorylation, 030306 microbiology, Cell Membrane, MESH: Host-Pathogen Interactions, MESH: CD4-Positive T-Lymphocytes / microbiology, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, medicine.disease, MESH: Dysentery, Bacillary / metabolism, Phosphoric Monoester Hydrolases, MESH: Cell Line, Cell culture, T cell migration, Parasitology, MESH: Phosphatidylinositol 4,5-Diphosphate / metabolism, MESH: Cell Membrane / chemistry, Transcription Factors, MESH: Dysentery, Bacillary / genetics

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