المؤلفون: Stephen K. Burley

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, 3D, Three-dimensional/Three dimensions, D3R, Drug Design Data Resource, Protein Conformation, Druggability, Protein Data Bank (RCSB PDB), Information Storage and Retrieval, PDBj, Protein Data Bank Japan, RCB Protein Data Bank, drug discovery and development, Biochemistry, US, United States, Drug Delivery Systems, Drug Discovery, structural biology, Databases, Protein, structure-guided drug discovery, FAIR principles, Drug discovery, mmCIF, Macromolecular Crystallographic Information File, computer.file_format, FAIR, Findability, Accessibility, Interoperability, and Reusability, BMRB, Biological Magnetic Resonance Data Bank, Small molecule, open-access biodata resource, Abl, Abelson Proto-oncogene 1, Nonreceptor Tyrosine Kinase, ADME, Absorption-Distribution-Metabolism-Excretion, PDBe, Protein Data Bank in Europe, wwPDB, Worldwide Protein Data Bank, drug target validation, HIV, Human Immunodeficiency Virus, 3DEM, Three-dimensional Electron Microscopy, Src, Proto-oncogene Sarcoma Tyrosine-protein Kinase, CDK4, Cyclin-dependent Kinase 4, PH+, Philadelphia Chromosome Positive, Computational biology, NMR, Nuclear Magnetic Resonance, Small Molecule Libraries, 03 medical and health sciences, Drug Development, Form and function, Protein Data Bank, PDB, Protein Data Bank, protein structure, PDBx, Protein Data Bank Exchange Data Dictionary, Molecular Biology, Biomedicine, EMDB, Electron Microscopy Data Bank, 030102 biochemistry & molecular biology, business.industry, CDK6, Cyclin-dependent Kinase 6, JBC Reviews, Proteins, RCSB, Research Collaboratory for Structural Bioinformatics, RNA, Ribonucleic Acid, Cell Biology, OneDep, Unified wwPDB System for Deposition, Biocuration, and Validation, FDA, Food and Drug Administration, QT Interval, Electrocardiogram Q-wave to T-wave Interval, 030104 developmental biology, Structural biology, PDB50, ID, Identifier, GIST, Gastrointestinal Stromal Tumor, IDH2, Isocitrate Dehydrogenase 2, MX, Macromolecular Crystallography, business, computer, CML, Chronic Myelogenous Leukemia, DNA, Deoxyribonucleic Acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a21b9caf1386840870f7909454ae2d5
https://pubmed.ncbi.nlm.nih.gov/33744282

المؤلفون: Satheeswaran Balasubramanian, Ekambaram Perumal, Vignesh Jeyamanickavel Mathan, Kanmani Gunasekaran, Saranyadevi Sasidharan

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 583-595 (2020)

مصطلحات موضوعية: microRNAs: Potential biomarkers of toxicity, Nrf2, Nuclear factor erythroid 2-related factor 2, Aβ, Amyloid Beta, Toxicology, 01 natural sciences, Non-coding RNAs, AHR, Aryl Hydrocarbon Receptor, 0302 clinical medicine, CDK6, Cyclin-dependent kinase 6, NMDAR, N-methyl-d-aspartate receptor, TP53, Tumor protein 53, BaP, Benzo[a]pyrene, NPs, Nanoparticles, Regulation of gene expression, Hpf, Hours post fertilization, qRT-PCR, quantitative Real Time-Polymerase Chain Reaction, CDKN1b, Cyclin-dependent kinase Inhibitor 1B, Wnt, Wingless-related integration site, HSPA1A, Heat shock 70 kDa protein 1, IL1R1, Interleukin 1 receptor, type 1, ER, Endoplasmic Reticulum, PDCD4, Programmed cell death protein 4, MC-RR, Microcystin-Arginine Arginine, RNAi, RNA interference, DGCR8, DiGeorge syndrome chromosomal [or critical] region 8, Epigenetics, GTP, Guanosine triphosphate, bcl2l11, B-cell lymphoma-2-like protein 11, TCDD, 2,3,7,8-Tetrachlorodibenzodioxin, RNA - Ribonucleic acid, lncRNAs, Long non-coding RNA, NFKBAP, NFKB Activating protein-1, COPD, Chronic obstructive pulmonary disease, PM2.5, Particulate Matter2.5, Environment, WHO, World Health Organization, 03 medical and health sciences, MRE, MicroRNA Response Elements, microRNA, SPIONs, Superparamagnetic Iron Oxide Nanoparticles, AMPK, Adenosine Monophosphate-activated protein kinase, lcsh:Toxicology. Poisons, NASH, Non-alcoholic steatohepatitis, CDK, Cyclin-dependent Kinase, CEC, Contaminants of Emerging Concern, RNase III, Ribonuclease III, LRP-1-, Low density lipoprotein receptor-related protein 1, MC-LR, Microcystin-Leucine Arginine, CCNB1, Cyclin B1, Ag, Silver, SiO2, Silicon dioxide, chemistry, LIN28B, Lin-28 homolog B, TRBP, Transactivation Response RNA Binding Protein, 030217 neurology & neurosurgery, Ahr aryl hydrocarbon receptor, Biomarkers, COX2, Cyclooxygenase-2, Au, Gold, ZEA, Zearalanone, Mn, Manganese, NF- ҡB, Nuclear Factor kappa-light-chain-enhancer of activated B cells, Health, Toxicology and Mutagenesis, Grp78/BIP, Binding immunoglobulin protein, 010501 environmental sciences, UTR, Untranslated region, chemistry.chemical_compound, ARRB1, Arrestin beta 1, RISC, RNA-induced silencing complex, Zn, Zinc, CTGF, Connective Tissue Growth Factor, NET1, Neuroepithelial Cell Transforming 1, BNIP3−3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, DNA, Deoxy ribonucleic acid, PFAS, Poly-fluoroalkyl substances, mRNA, Messenger RNA, ripk 1, Receptor-interacting serine/threonine-protein kinase 1, Toxicity, Fadd, Fas-associated protein with death domain, IL-6, Interleukin 6, SOLiD, Sequencing by Oligonucleotide Ligation and Detection, Al2O3, Aluminium oxide, ceRNA, Competing endogenous RNA, Computational biology, Biology, SEMA6D, Semaphorin-6D, BCB, Blood-cerebrospinal fluid barrier, ADAMTS9, A disintegrin and metalloproteinase with thrombospondin motifs 9, CDC25A, M-phase inducer phosphatase 1, lcsh:RA1190-1270, CDK1, Cyclin-dependent kinase 1, DON, Deoxynivalenol, RNA, Ribonucleic acid, TNF-α, Tumor necrosis factor – alpha, 0105 earth and related environmental sciences, ComputingMethodologies_COMPUTERGRAPHICS, miRNA, MicroRNA, MAPK, Mitogen Activated Protein Kinase, Gene regulation, CDC25C, M-phase inducer phosphatase 3, Xenobiotic, MiRNA biogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9ee14a85356d66a24aeb2b5ac399f7
https://pubmed.ncbi.nlm.nih.gov/32426239

المؤلفون: Daniel Monleon, Pedro Roldán, Lara Navarro, Teresa San-Miguel, Javier Megías, Concha López-Ginés, Lisandra Muñoz-Hidalgo, Miguel Cerdá-Nicolás

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 1, Pp 10-21 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Biopsy, L-amp GB, EGFR-low amplified glioblastoma, medicine.disease_cause, wt, wildtype, MYBPC3, myosin-binding protein C, 0302 clinical medicine, HIC1, hypermethylated in cancer 1, Gene duplication, In Situ Hybridization, Fluorescence, IDH2, isocitrate dehydrogenase 2, Mutation, RB-pat, RB signaling pathway, EGFRvIII, epidermal growth factor receptor variant number III, PAH, phenylalanine hydroxylase, GBM, glioblastoma, IDH-wildtype (glioblastoma multiforme, primary glioblastoma), ANOVA, ANalysis Of VAriance, N-amp GB, EGFR-no amplified glioblastoma, Middle Aged, CDKN2A, cyclin-dependent kinase inhibitor 2A, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Primary tumor, Immunohistochemistry, H-amp GB, EGFR-high amplified glioblastoma, ErbB Receptors, TKR-pat, tyrosine-kinase receptors signaling pathway, 030220 oncology & carcinogenesis, Disease Progression, CDK6, cyclin-dependent kinase 6, CDH1, Cadherin 1, Female, CREM, cAMP response element modulator, IHC, immunohistochemistry, Adult, Original article, DNA Copy Number Variations, CDKN1B, cyclin-dependent kinase inhibitor 1B, Biology, RARB, retinoic acid receptor beta, CNS, central nervous system, lcsh:RC254-282, IDH1, isocitrate dehydrogenase 1, BCL2, B-cell cll/ lymphoma 2, CNAs, copy number algerations, WHO, World Health Organization, 03 medical and health sciences, Young Adult, p53-pat, p53 signaling pathway, medicine, Biomarkers, Tumor, TMA, tissue microarray, PTEN, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Survival analysis, Aged, Genetic heterogeneity, Gene Amplification, GFAP, glial fibrillary acidic protein, MLPA, multiplex ligation-dependent probe amplification, medicine.disease, FISH, fluorescence in situ hibridization, Survival Analysis, CDKN2B, cyclin-dependent kinase inhibitor 2B, PTEN, phosphatase and tensin homolog, EGFR, epidermal growth factor receptor, CNV-load, load of copy number variations, 030104 developmental biology, PARK2, parkin, Cancer research, biology.protein, TCGA, The Cancer Genome Atlas, LARGE1, acetylglucosaminyltransferase-like protein 1, Glioblastoma, CHD7, Chromodomain Helicase DNA Binding Protein 7, DAPI, 4′,6-diamidino-2-phenylindole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071c5ffa07d10f257ddbf1bca2c7a8ee
https://pubmed.ncbi.nlm.nih.gov/31751860

المؤلفون: Michele A. Battle, Emily M. Walker, Bridget M. Kohlnhofer, Cayla A. Thompson

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 189-209 (2016)

مصطلحات موضوعية: EdU, 5-ethynyl-2'deoxyuridine, 0301 basic medicine, Prdm1, PR domain containing 1, endocrine system, Frizzled, Morphogenesis, Biology, Pdgfa, platelet-derived growth factor α, Villus Morphogenesis, Bio-ChIP-Seq, biotin-mediated chromatin immunoprecipitation with high-throughput sequencing, cKO, conditional knockout, SBS, short-bowel syndrome, PDGFRA, platelet-derived growth factor receptor α, 03 medical and health sciences, PCR, polymerase chain reaction, Cyclin D2, medicine, Olfm4, olfactomedin 4, lcsh:RC799-869, Sonic hedgehog, reproductive and urinary physiology, Original Research, Transcriptional Regulation, Hes1/6, hairy and enhancer of split-1/6, E, embryonic day, Hepatology, WNT Signaling, Ccnd1/2, cyclin D1/2, Cdk6, cyclin-dependent kinase 6, Atoh, atonal homolog 1, Gastroenterology, Wnt signaling pathway, Fzd5, frizzled 5, respiratory system, Intestinal epithelium, Molecular biology, Epithelium, 030104 developmental biology, medicine.anatomical_structure, Wnt, wingless type MMTV integration site family, embryonic structures, Shh, sonic hedgehog, cardiovascular system, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, Endoderm

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82fd5716bbb6773e37720f300cbfbe6

المؤلفون: Biao Tang, Hongmei Hu, Wenying Yan

المصدر: European Journal of Obstetrics & Gynecology and Reproductive Biology: X, Vol 5, Iss, Pp-(2020)
European Journal of Obstetrics & Gynecology and Reproductive Biology: X

مصطلحات موضوعية: NATs, natural antisense transcripts, SRA, Steroid receptor RNA activator, Gynecological disease, Endometriosis, lncRNAs, EMs, Endometriosis, Review, CDK6, cyclin dependent kinase 6, Biology, Bioinformatics, lcsh:Gynecology and obstetrics, medicine, RNA molecule, Non-coding RNA, lcsh:RG1-991, Igf2, insulin-like growth factor 2, ncRNAs, non-coding RNAs, lncRNAs, long non-coding RNAs, Obstetrics and Gynecology, RNA, SRAP, steroid receptor activator protein, Early diagnosis, medicine.disease, Medical research, Long non-coding RNA, Igf1r, insulin-like growth factor-1 receptor, Reproductive Medicine, piRNAs, PIWI-interacting RNAs, snRNAs, small nuclear RNAs, siRNAs, short inhibitory RNAs, HIF-1α, Hypoxia inducible factor-1alpha

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a2f6d62051c7a7aa6bcfeffc186129
https://doi.org/10.1016/j.eurox.2019.100067

المؤلفون: Masyuk T; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Masyuk A; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Trussoni C; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Howard B; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Ding J; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Huang B; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., LaRusso N; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

المصدر: JHEP reports : innovation in hepatology [JHEP Rep] 2021 Aug 05; Vol. 3 (5), pp. 100345. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: PubMed not MEDLINE

المؤلفون: Balasubramanian S; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Gunasekaran K; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Sasidharan S; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Jeyamanickavel Mathan V; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Perumal E; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.

المصدر: Toxicology reports [Toxicol Rep] 2020 May 04; Vol. 7, pp. 583-595. Date of Electronic Publication: 2020 May 04 (Print Publication: 2020).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Ireland Ltd Country of Publication: Ireland NLM ID: 101630272 Publication Model: eCollection Cited Medium: Internet ISSN: 2214-7500 (Electronic) Linking ISSN: 22147500 NLM ISO Abbreviation: Toxicol Rep Subsets: PubMed not MEDLINE

المؤلفون: Yan W; Department of Gynecology, Wangjiang Hospital, Sichuan University, China, No. 24, South Section of First Ring Road, Chengdu City, Sichuan Province, China., Hu H; Department of Gynecology, Sichuan Maternal and Child Health Hospital, No. 290 Shayan West Second Street, Jinyang Road, Chengdu City, Sichuan Province, China., Tang B; Department of Gynecology, Sichuan Maternal and Child Health Hospital, No. 290 Shayan West Second Street, Jinyang Road, Chengdu City, Sichuan Province, China.

المصدر: European journal of obstetrics & gynecology and reproductive biology: X [Eur J Obstet Gynecol Reprod Biol X] 2019 Jun 15; Vol. 5, pp. 100067. Date of Electronic Publication: 2019 Jun 15 (Print Publication: 2020).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101750520 Publication Model: eCollection Cited Medium: Internet ISSN: 2590-1613 (Electronic) Linking ISSN: 25901613 NLM ISO Abbreviation: Eur J Obstet Gynecol Reprod Biol X Subsets: PubMed not MEDLINE

المصدر: DTIC AND NTIS

مصطلحات الفهرس: Genetic Engineering and Molecular Biology, Anatomy and Physiology, Medicine and Medical Research, INTERACTIONS, PROTEINS, PROSTATE CANCER, HORMONES, HUMANS, THERAPY, IN VIVO ANALYSIS, CELLS(BIOLOGY), PROSTATE GLAND, ANDROGENS, TESTOSTERONE, TRANSCRIPTION(GENETICS)., ANDROGEN RECEPTORS, CELL CYCLE CONTROL, CDK6(CYCLIN DEPENDENT KINASE 6), GENE EXPRESSION, HORMONE DEPENDENCE, Text

URL: https://apps.dtic.mil/docs/citations/ADA415662

المؤلفون: Pekkonen P; a Institute of Biotechnology ; University of Helsinki ; Helsinki , Finland., Järviluoma A, Zinovkina N, Cvrljevic A, Prakash S, Westermarck J, Evan GI, Cesarman E, Verschuren EW, Ojala PM

المصدر: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2014; Vol. 13 (23), pp. 3670-84.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE

مواضيع طبية MeSH: Cyclin-Dependent Kinase 6/*metabolism , Herpesvirus 8, Human/*metabolism , Lymphoma, T-Cell/*metabolism , Receptors, Notch/*metabolism , T-Lymphocytes/*metabolism, Animals ; Cell Line, Tumor ; HEK293 Cells ; Humans ; Lymphoma, T-Cell/virology ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Mice, Transgenic ; Receptor, Notch3 ; T-Lymphocytes/virology