المؤلفون: Jihui Kang, Wenjuan Zhang, Yupei Liang, Hongfeng Ruan, Guoan Chen, Yunjing Zhang, Lili Cai, Xiaojun Liu, Yanyu Jiang, Shiwen Wang, Mingsong Wang, Lijun Jia, Lihui Li

المصدر: EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Male, Proteomics, Research paper, Lung Neoplasms, Apoptosis, Wine, NEDD8, Protein neddylation, Mice, 0302 clinical medicine, FACS, fluorescence-activated cell sorting, NEDD8 Activating Enzyme, NAE, NEDD8-activating enzyme, Molecular Targeted Therapy, GFP, green fluorescent protein, Gene knockdown, CDKN1B, Cyclin Dependent Kinase Inhibitor 1B, p27, General Medicine, Cell cycle, Gene Expression Regulation, Neoplastic, UBC12, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Heterografts, Female, Lung cancer, Cullin, Signal Transduction, China, NEDD8 Protein, Overcome drug resistance, CDKN1A, Cyclin Dependent Kinase Inhibitor 1A, p21, Cyclopentanes, Biology, Cell-cycle arrest, General Biochemistry, Genetics and Molecular Biology, SPSS, Statistical Program for Social Sciences software, 03 medical and health sciences, Anticancer target, CHX, cycloheximide, Animals, Humans, Ubiquitins, Cell Proliferation, 030104 developmental biology, Pyrimidines, A549 Cells, Ubiquitin-Conjugating Enzymes, Cancer research, biology.protein, Commentary, CDKN1B, Neddylation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c293566d5e8404cb98116077d2388d8
http://europepmc.org/articles/PMC6642072

المؤلفون: Zhang, K, Wong, P, Zhang, L, Jacobs, B, Borden, E C, Aster, J C, Bedogni, B^{Aff1, IDonc2011606_cor7}

المصدر: Oncogene. 31(43):4609-4618

المؤلفون: Satheeswaran Balasubramanian, Ekambaram Perumal, Vignesh Jeyamanickavel Mathan, Kanmani Gunasekaran, Saranyadevi Sasidharan

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 583-595 (2020)

مصطلحات موضوعية: microRNAs: Potential biomarkers of toxicity, Nrf2, Nuclear factor erythroid 2-related factor 2, Aβ, Amyloid Beta, Toxicology, 01 natural sciences, Non-coding RNAs, AHR, Aryl Hydrocarbon Receptor, 0302 clinical medicine, CDK6, Cyclin-dependent kinase 6, NMDAR, N-methyl-d-aspartate receptor, TP53, Tumor protein 53, BaP, Benzo[a]pyrene, NPs, Nanoparticles, Regulation of gene expression, Hpf, Hours post fertilization, qRT-PCR, quantitative Real Time-Polymerase Chain Reaction, CDKN1b, Cyclin-dependent kinase Inhibitor 1B, Wnt, Wingless-related integration site, HSPA1A, Heat shock 70 kDa protein 1, IL1R1, Interleukin 1 receptor, type 1, ER, Endoplasmic Reticulum, PDCD4, Programmed cell death protein 4, MC-RR, Microcystin-Arginine Arginine, RNAi, RNA interference, DGCR8, DiGeorge syndrome chromosomal [or critical] region 8, Epigenetics, GTP, Guanosine triphosphate, bcl2l11, B-cell lymphoma-2-like protein 11, TCDD, 2,3,7,8-Tetrachlorodibenzodioxin, RNA - Ribonucleic acid, lncRNAs, Long non-coding RNA, NFKBAP, NFKB Activating protein-1, COPD, Chronic obstructive pulmonary disease, PM2.5, Particulate Matter2.5, Environment, WHO, World Health Organization, 03 medical and health sciences, MRE, MicroRNA Response Elements, microRNA, SPIONs, Superparamagnetic Iron Oxide Nanoparticles, AMPK, Adenosine Monophosphate-activated protein kinase, lcsh:Toxicology. Poisons, NASH, Non-alcoholic steatohepatitis, CDK, Cyclin-dependent Kinase, CEC, Contaminants of Emerging Concern, RNase III, Ribonuclease III, LRP-1-, Low density lipoprotein receptor-related protein 1, MC-LR, Microcystin-Leucine Arginine, CCNB1, Cyclin B1, Ag, Silver, SiO2, Silicon dioxide, chemistry, LIN28B, Lin-28 homolog B, TRBP, Transactivation Response RNA Binding Protein, 030217 neurology & neurosurgery, Ahr aryl hydrocarbon receptor, Biomarkers, COX2, Cyclooxygenase-2, Au, Gold, ZEA, Zearalanone, Mn, Manganese, NF- ҡB, Nuclear Factor kappa-light-chain-enhancer of activated B cells, Health, Toxicology and Mutagenesis, Grp78/BIP, Binding immunoglobulin protein, 010501 environmental sciences, UTR, Untranslated region, chemistry.chemical_compound, ARRB1, Arrestin beta 1, RISC, RNA-induced silencing complex, Zn, Zinc, CTGF, Connective Tissue Growth Factor, NET1, Neuroepithelial Cell Transforming 1, BNIP3−3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, DNA, Deoxy ribonucleic acid, PFAS, Poly-fluoroalkyl substances, mRNA, Messenger RNA, ripk 1, Receptor-interacting serine/threonine-protein kinase 1, Toxicity, Fadd, Fas-associated protein with death domain, IL-6, Interleukin 6, SOLiD, Sequencing by Oligonucleotide Ligation and Detection, Al2O3, Aluminium oxide, ceRNA, Competing endogenous RNA, Computational biology, Biology, SEMA6D, Semaphorin-6D, BCB, Blood-cerebrospinal fluid barrier, ADAMTS9, A disintegrin and metalloproteinase with thrombospondin motifs 9, CDC25A, M-phase inducer phosphatase 1, lcsh:RA1190-1270, CDK1, Cyclin-dependent kinase 1, DON, Deoxynivalenol, RNA, Ribonucleic acid, TNF-α, Tumor necrosis factor – alpha, 0105 earth and related environmental sciences, ComputingMethodologies_COMPUTERGRAPHICS, miRNA, MicroRNA, MAPK, Mitogen Activated Protein Kinase, Gene regulation, CDC25C, M-phase inducer phosphatase 3, Xenobiotic, MiRNA biogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9ee14a85356d66a24aeb2b5ac399f7
https://pubmed.ncbi.nlm.nih.gov/32426239

المؤلفون: Anna P. Kipp, Stefanie Deubel, Elias S.J. Arnér, Katarina Johansson

المصدر: Redox Biology
Redox Biology, Vol 12, Iss, Pp 403-409 (2017)

مصطلحات موضوعية: PHD, prolyl hydroxylase domain proteins, Transcriptional Activation, CDKN1B, cyclin-dependent kinase inhibitor 1B (p27), SCM, stem cell medium, NFE2L2 or Nrf2, nuclear factor (erythroid-derived 2)-like 2, NF-E2-Related Factor 2, Cell Culture Techniques, XCT, cystine-glutamate exchange transporter, Models, Biological, Nrf2, NF-κB, Spheroids, Cellular, GSH, glutathione, HIF, Humans, lcsh:QH301-705.5, HIF, hypoxia inducible factor, lcsh:R5-920, DMOG, dimethyloxalylglycine, Cancer stem cells, NCL, nucleolin, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, MUC2, mucin2, NF-kappa B, pTRAF, plasmid for transcription factor reporter activation based on fluorescence, HCT116 Cells, CSC, cancer stem cell, Amino Acids, Dicarboxylic, Gene Expression Regulation, Neoplastic, lcsh:Biology (General), AUR, auranofin, CA9, carbonic anhydrase IX, Redox regulation, embryonic structures, Neoplastic Stem Cells, Hypoxia-Inducible Factor 1, Spheroids, lcsh:Medicine (General), ROSI, rosiglitazone, Oxidation-Reduction, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f4d61526fa1062febdeb9131e25dab39
http://europepmc.org/articles/PMC5357678

المؤلفون: Daniel Monleon, Pedro Roldán, Lara Navarro, Teresa San-Miguel, Javier Megías, Concha López-Ginés, Lisandra Muñoz-Hidalgo, Miguel Cerdá-Nicolás

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 1, Pp 10-21 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Biopsy, L-amp GB, EGFR-low amplified glioblastoma, medicine.disease_cause, wt, wildtype, MYBPC3, myosin-binding protein C, 0302 clinical medicine, HIC1, hypermethylated in cancer 1, Gene duplication, In Situ Hybridization, Fluorescence, IDH2, isocitrate dehydrogenase 2, Mutation, RB-pat, RB signaling pathway, EGFRvIII, epidermal growth factor receptor variant number III, PAH, phenylalanine hydroxylase, GBM, glioblastoma, IDH-wildtype (glioblastoma multiforme, primary glioblastoma), ANOVA, ANalysis Of VAriance, N-amp GB, EGFR-no amplified glioblastoma, Middle Aged, CDKN2A, cyclin-dependent kinase inhibitor 2A, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Primary tumor, Immunohistochemistry, H-amp GB, EGFR-high amplified glioblastoma, ErbB Receptors, TKR-pat, tyrosine-kinase receptors signaling pathway, 030220 oncology & carcinogenesis, Disease Progression, CDK6, cyclin-dependent kinase 6, CDH1, Cadherin 1, Female, CREM, cAMP response element modulator, IHC, immunohistochemistry, Adult, Original article, DNA Copy Number Variations, CDKN1B, cyclin-dependent kinase inhibitor 1B, Biology, RARB, retinoic acid receptor beta, CNS, central nervous system, lcsh:RC254-282, IDH1, isocitrate dehydrogenase 1, BCL2, B-cell cll/ lymphoma 2, CNAs, copy number algerations, WHO, World Health Organization, 03 medical and health sciences, Young Adult, p53-pat, p53 signaling pathway, medicine, Biomarkers, Tumor, TMA, tissue microarray, PTEN, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Survival analysis, Aged, Genetic heterogeneity, Gene Amplification, GFAP, glial fibrillary acidic protein, MLPA, multiplex ligation-dependent probe amplification, medicine.disease, FISH, fluorescence in situ hibridization, Survival Analysis, CDKN2B, cyclin-dependent kinase inhibitor 2B, PTEN, phosphatase and tensin homolog, EGFR, epidermal growth factor receptor, CNV-load, load of copy number variations, 030104 developmental biology, PARK2, parkin, Cancer research, biology.protein, TCGA, The Cancer Genome Atlas, LARGE1, acetylglucosaminyltransferase-like protein 1, Glioblastoma, CHD7, Chromodomain Helicase DNA Binding Protein 7, DAPI, 4′,6-diamidino-2-phenylindole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071c5ffa07d10f257ddbf1bca2c7a8ee
https://pubmed.ncbi.nlm.nih.gov/31751860

المؤلفون: Balasubramanian S; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Gunasekaran K; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Sasidharan S; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Jeyamanickavel Mathan V; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India., Perumal E; Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore, 641 046, India.

المصدر: Toxicology reports [Toxicol Rep] 2020 May 04; Vol. 7, pp. 583-595. Date of Electronic Publication: 2020 May 04 (Print Publication: 2020).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Ireland Ltd Country of Publication: Ireland NLM ID: 101630272 Publication Model: eCollection Cited Medium: Internet ISSN: 2214-7500 (Electronic) Linking ISSN: 22147500 NLM ISO Abbreviation: Toxicol Rep Subsets: PubMed not MEDLINE

المؤلفون: Pan Y; a Jiangsu Engineering Research Center for microRNA Biology and Biotechnology; State Key Laboratory of Pharmaceutical Biotechnology; School of Life Sciences; Nanjing University ; Nanjing , Jiangsu , China., Liang H, Chen W, Zhang H, Wang N, Wang F, Zhang S, Liu Y, Zhao C, Yan X, Zhang J, Zhang CY, Gu H, Zen K, Chen X

المصدر: RNA biology [RNA Biol] 2015; Vol. 12 (3), pp. 276-89.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Carcinogenesis/*genetics , Colorectal Neoplasms/*genetics , GPI-Linked Proteins/*genetics , MicroRNAs/*genetics, Animals ; Caco-2 Cells ; Carcinogenesis/metabolism ; Carcinogenesis/pathology ; Cell Proliferation ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Cyclin-Dependent Kinase Inhibitor p27/genetics ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; GPI-Linked Proteins/metabolism ; HT29 Cells ; Humans ; Mice ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/metabolism ; Neoplasm Transplantation ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; S-Phase Kinase-Associated Proteins/genetics ; S-Phase Kinase-Associated Proteins/metabolism ; Signal Transduction ; Transfection

المؤلفون: Vucicevic L; a Institute for Biological Research ; University of Belgrade ; Belgrade , Serbia., Misirkic-Marjanovic M, Paunovic V, Kravic-Stevovic T, Martinovic T, Ciric D, Maric N, Petricevic S, Harhaji-Trajkovic L, Bumbasirevic V, Trajkovic V

المصدر: Autophagy [Autophagy] 2014; Vol. 10 (12), pp. 2362-78.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

مواضيع طبية MeSH: Antipsychotic Agents/*pharmacology , Autophagy/*drug effects , Benzodiazepines/*pharmacology , Lysosomes/*drug effects , Mitochondria/*drug effects , Neurons/*drug effects, AMP-Activated Protein Kinases/metabolism ; Animals ; Apoptosis/drug effects ; Cell Line ; Humans ; Mice ; Neurons/cytology ; Olanzapine ; Reactive Oxygen Species/metabolism