المؤلفون: Rosario Francisco-Velilla, Azman Embarc-Buh, Salvador Abellan, Francisco del Caño-Ochoa, Santiago Ramón-Maiques, Encarnacion Martinez-Salas

المساهمون: Ministerio de Ciencia e Innovación (España), European Commission, Comunidad de Madrid, Fundación Ramón Areces, Generalitat Valenciana, Ramon-Maiques, Santiago, del Caño-Ochoa, Francisco, Martinez-Salas, Encarnacion

المصدر: Computational and Structural Biotechnology Journal. 20:6182-6191

مصطلحات موضوعية: Gemin5 interactome, SMN complex, WD-40, tryptophan-aspartic repeat motif, Phosphoresidues, TPR-like, tetratricopeptide repeat-like domain, BiNGO, Biological Networks Gene Ontology application, Biophysics, eIF4E, eukaryotic initiation factor 4E, RNA-binding proteins, Human variants, Biochemistry, CHX, cycloheximide, Structural Biology, NEDCAM, neurological disorders with cerebellar atrophy and motor dysfunction, SMN, survival of motor neurons, Genetics, TAP, tandem affinity purification, SGs, stress granules, RBS1, RNA-binding site1, MD, molecular dynamics, Computer Science Applications, IRES, internal ribosome entry site, snRNAs, small nuclear RNAs, Protein structure modeling, RBP, RNA-binding protein, Protein synthesis, Neurological disease, LC-MS/MS, liquid chromatography-mass spectrometry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8652d46d882bca23b654b6376c05d46
https://doi.org/10.1016/j.csbj.2022.11.018

المؤلفون: Ying Yan, Chitra Palanivel, Charles A. Enke, Geoffrey A. Talmon, Nichole D. Brandquist, Keith R. Johnson, Lepakshe S. V. Madduri, Michael J. Baine, Sumin Zhou, Michel M. Ouellette

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1192-1203 (2021)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: p53, Cancer Research, FBXL20, F-Box and Leucine-Rich Repeat Protein 20, Ubiquitin, Dox, Doxycycline, PP2A, protein phosphatase 2A, Protein Phosphatase 2, siRNA, short interfering RNA, RC254-282, Original Research, Gene knockdown, DMEM, Dulbecco's modified Eagle's medium, FBXL20, biology, Protein Stability, Chemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, IP, immunoprecipitation, SCF, Skp1_Cullin1_F-box, Ubiquitin ligase, Cell biology, PP2A, c-Myc, shRNA, short hairpin RNA, Phosphorylation, IHC, immunohistochemistry, Signal Transduction, wt, wild-type, Protein subunit, Phosphatase, LATS, Large Tumor Suppressor Kinase, CHX, cycloheximide, KSR, Kinase Suppressor of Ras 1, Cell Line, Tumor, Skp1, Humans, IB, immunoblotting, PR55α, HPNE, human normal pancreatic cells, esiRNAs, endoribonuclease-prepared siRNAs, ATCC, American Type Culture Collection, F-Box Proteins, DMSO, Dimethyl sulfoxide, Protein phosphatase 2, RT-PCR, Reverse Transcription Polymerase Chain Reaction, YAP, Yes-associated protein, Pancreatic Neoplasms, biology.protein, Tumor Suppressor Protein p53, HPV16, human papillomavirus 16

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f832db5958c0092cf4988a30bef03318
http://www.sciencedirect.com/science/article/pii/S1476558621000877

المؤلفون: Mingxiao Yin, Xiaojia Liu, Na Zhang, Genxiang Mao, Lu Liu, Hongbin Deng, Peng Yang, Wenjian Min, Kuang Ze'an, Jingwen Dong

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3134-3149 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, CQ, chloroquine, mTORC1, Transcription factor EB, urologic and male genital diseases, TFEB, nuclear transcriptional factor EB, CETSA, cellular thermal shift assay, 0302 clinical medicine, Cancer immunotherapy, ICB, immune checkpoint blockade, General Pharmacology, Toxicology and Pharmaceutics, p70S6K, phosphorylation of p70 S6 kinase, 0303 health sciences, biology, Chemistry, qRT-PCR, quantitative real-time polymerase chain reaction, Lysosome, medicine.anatomical_structure, 030220 oncology & carcinogenesis, mTOR, Original Article, IHC, immunohistochemistry, PD-L1, SPR, surface plasmon resonance, mTOR, mammalian target of rapamycin, RM1-950, PD-L1, programmed cell death ligand- 1, 03 medical and health sciences, CHX, cycloheximide, NSCLC, non-small cell lung cancer, Tregs, regulatory T-lymphocytes, medicine, NAG, β-N-acetylglucosaminidase, IB, immunoblotting, PI3K/AKT/mTOR pathway, 030304 developmental biology, PD-1, programmed cell death-1, Baf, bafilomycin A1, Immune checkpoint, 4EBP1, eIF4E-binding protein 1, TILs, tumor-infiltrating lymphocytes, Cancer cell, biology.protein, Cancer research, TFEB, LLC, Lewis lung carcinoma, Therapeutics. Pharmacology, TBM-1, tubeimoside-1, Immune checkpoint blockade

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d344df92d314f733377ab3c9584020
http://www.sciencedirect.com/science/article/pii/S2211383521001118

المؤلفون: Jian Liu, Qi Lv, Yinan Zhang, Yao Xing, Dong Dong, Yue Liu, Lihong Hu, Hongzhi Qiao

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)

مصطلحات موضوعية: PMSF, phenylmethanesulfonyl fluoride, MPO, myeloperoxidase, ATG7, autophagy-related protein 7, DMSO, dimethyl sulfoxide, CETSA, cellular thermal shift assay, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, General Pharmacology, Toxicology and Pharmaceutics, M-CSF, macrophage colony stimulating factor, 0303 health sciences, Chemistry, BMDMs, bone marrow-derived macrophages, EZH2, Inflammasome, ELISA, enzyme-linked immunosorbent assay, Colitis, PMA, phorbol myristate acetate, Ulcerative colitis, ChIP, chromatin immunoprecipitation, 030220 oncology & carcinogenesis, Histone methyltransferase, LPS, lipopolysaccharide, Original Article, DAI, disease activity index, medicine.drug, AIM2, absent in melanoma 2, ATP, adenosine triphosphate, ECL, enhanced chemiluminescent, 3-MC, 3-methylcholanthrene, ATG5, RM1-950, macromolecular substances, SIP, solvent-induced protein precipitation, Lonicerin, 03 medical and health sciences, CHX, cycloheximide, FBS, fetal bovine serum, PAMPs, pathogen-associated molecular patterns, DSS, dextran sulfate sodium, Autophagy, medicine, Epigenetics, TEM, transmission electron microscopy, 030304 developmental biology, EDTA, ethylenediaminetetraacetic acid, RMSF, root mean-square fluctuation, RMSD, root mean-square deviation, MDP, muramyldipeptide, medicine.disease, NLRP3 inflammasome, ATG5, autophagy-related protein 5, MSU, monosodium urate crystals, UC, ulcerative colitis, 5-ASA, 5-aminosalicylic acid, DTT, dithiothreitol, DAMPs, damage-associated molecular patterns, H&E, hematoxylin and eosin, Cancer research, Therapeutics. Pharmacology, NLRP3, nucleotide-binding domain-like receptors family pyrin domain containing 3, PRC2, polycomb repressive complex 2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b197d7e1bd61447a9d7a45da0a56387
https://doi.org/10.1016/j.apsb.2021.03.011

المؤلفون: Karin A. Vallega, Shuo Zhang, Puyu Shi, Shi-Yong Sun, Liang Deng

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 8, Pp 766-774 (2021)

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Lung Neoplasms, EGFR-TKI, EGFR tyrosine kinase inhibitor, Act D, actinomycin D, Mutant, EGFR-TKIs, Mice, Transactivation, Osimertinib, skin and connective tissue diseases, Receptor, RC254-282, Original Research, EGFR inhibitors, Protein Stability, Chemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Proto-Oncogene Proteins c-met, ErbB Receptors, Gene Expression Regulation, Neoplastic, MET, Heterografts, Lung cancer, DR4, death receptor4, musculoskeletal diseases, Cell Survival, MAP Kinase Signaling System, MFI, mean fluorescent intensity, Models, Biological, siRNA, small intergering RNA, CHX, cycloheximide, DR5, death receptor 5, Cell Line, Tumor, NSCLC, non-small cell lung cancer, TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, Animals, Humans, DR4, Protein Kinase Inhibitors, EGFR, epidermal growth factor recetptor, Gene Amplification, Transcription Factor AP-1, Disease Models, Animal, Receptors, TNF-Related Apoptosis-Inducing Ligand, Drug Resistance, Neoplasm, Cell culture, Apoptosis, SRB, sulforhodamine B, Cancer research, Acquired resistance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e6a057877b0a1f933980bc065e9a2d
https://doi.org/10.1016/j.neo.2021.06.006

المؤلفون: Vidal, Jean^Aff4, Bakrim, Nadia^Aff4, Hodges, Michael^Aff4

المساهمون: Govindjee, editor^Aff1, Foyer, Christine H., editor^Aff2, Noctor, Graham, editor^Aff3

المصدر: Photosynthetic Nitrogen Assimilation and Associated Carbon and Respiratory Metabolism. 12:135-150

المؤلفون: Yi-Chao Zheng, Hong-Min Liu, Ouwen Li, Jun-Wei Wang, Zhenhe Suo, Fengyu Qi, Wen-Ting Kang, Pengxing He, Zhi-Ru Wang, Yinghua You

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 694-707 (2021)

مصطلحات موضوعية: USP18, ubiquitin specific peptidase 18, medicine.medical_treatment, RIPA, radioimmunoprecipitation, PTMs, post-translational modifications, WB, Western blotting, 0302 clinical medicine, General Pharmacology, Toxicology and Pharmaceutics, HDN, well differentiated matched adjacent normal tissues, 0303 health sciences, PDN, poor differentiated matched adjacent normal tissues, biology, USP7, ubiquitin-specific processing protease 7, HDT, well differentiated tumor tissues, TCR, T cell receptor, Melanoma, DUB, deubiquitinating enzymes, PDT, poor differentiated tumor tissues, medicine.anatomical_structure, PBMC, peripheral blood mononuclear cells, 030220 oncology & carcinogenesis, GC, gastric cancer, Original Article, Epigenetics, USP22, ubiquitin specific peptidase 22, Immunotherapy, PD-L1, T cell, TCGA, the Cancer Genome Atlas, Cancer biology, irAEs, immune-related adverse effects, H2O2, hydrogen peroxidase, TILs, tumor-infiltrating T cells, PD-1, programmed cell death protein 1, 03 medical and health sciences, Immune system, PBS, phosphate buffer saline, Downregulation and upregulation, CHX, cycloheximide, medicine, HAUSP, herpes virus-associated ubiquitin-specific protease, EBNA1, Epstein–Barr nuclear antigen 1, 030304 developmental biology, Bladder cancer, ICP0, infected cell protein 0, business.industry, qRT-PCR, quantitative real time polymerase chain reaction, lcsh:RM1-950, Ubiquitination, GEPIA, Gene-Expression Profiling Interactive Analysis, medicine.disease, BCA, bicinchoninic acid, MDM2, murine double minute-2, USP38, ubiquitin specific peptidase 38, FDA, U.S. Food and Drug Administration, PD-L1, programmed death ligand-1, lcsh:Therapeutics. Pharmacology, FOXO4, forkhead box O4, USP9X, ubiquitin specific peptidase 9 X-linked, Cancer cell, biology.protein, Cancer research, USP7, IL-2, interleukin 2, CSN5, COP9 signalosome 5, business, Gastric cancer, Immunosuppression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3f6e9de03bb3ad460a61d5471e4bca
http://europepmc.org/articles/PMC7982505

المؤلفون: Marta Acchioni, Anna Lisa Remoli, Angela Battistini, Robert Clarke, Chiara Acchioni, Giulia Marsili, Roberto Orsatti, Edvige Perrotti, Marco Sgarbanti

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 10, Pp 459-469 (2020)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Apoptosis, IκB kinase, medicine.disease_cause, environment and public health, IRFs, interferon regulatory factors, WB, western blot, 0302 clinical medicine, FOXO3a, forkhead box O 3a, NRU, neutral red uptake, Tumor Cells, Cultured, SDS, sodium dodecyl sulphate, skin and connective tissue diseases, Ub, ubiquitin, IRF-1, Chemistry, phosphorylation, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, WCE, whole cell extract, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, I-kappa B Kinase, Ni-NTA, nickel-nitrilotriacetic acid, HS, horse serum, protein stability, 030220 oncology & carcinogenesis, Phosphorylation, Female, Signal Transduction, Original article, CYLD, cylindromatosis, Breast Neoplasms, lcsh:RC254-282, CTR, control, 03 medical and health sciences, Breast cancer, breast cancer, CHX, cycloheximide, PBS, phosphate buffered saline, medicine, Humans, IFN, interferon, TBK-1, TANK Binding Kinase 1, TRAF2, tumor necrosis factor receptor-associated factor 2, Cell Proliferation, hEGF, human Epidermal Growth Factor, Innate immune system, Ubiquitin, Cell growth, Ubiquitination, ERα, estrogen receptor α, GST, glutathione S trasferase, medicine.disease, Stat-1, signal transducer and activator of transcription-1, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Proteolysis, Cancer research, HDM2, human double minute 2 protein, IKK-ε, inhibitor of nuclear factor kappa-B kinase-ε, K48 polyubiquitination, FCS, fetal calf serum, Carcinogenesis, PCNA, Proliferating Cell Nuclear Antigen, IKK-ε, Interferon Regulatory Factor-1, Interferon regulatory factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dc31ce8201d10ab9e5e10769229024
http://www.sciencedirect.com/science/article/pii/S1476558620301354

المؤلفون: Vidal, Jean^Aff12, Coursol, Sylvie^Aff12, Pierre, Jean-Noël^Aff12

المساهمون: Govindjee, editor^Aff1, Aro, Eva-Mari, editor^{Aff2, Aff10}, Foyer, Christine, editor^Aff3, Gantt, Elisabeth, editor^Aff4, Golbeck, John H., editor^Aff5, Golden, Susan S., editor^Aff6, Junge, Wolfgang, editor^Aff7, Michel, Hartmut, editor^Aff8, Satoh, Kirmiyuki, editor^Aff9, Andersson, Bertil, editor^Aff11

المصدر: Regulation of Photosynthesis. 11:363-375

المؤلفون: Marius Winkler, Juliane Friedrich, Cathinka Boedicker, Nadezda Dolgikh

المصدر: Translational Oncology, Vol 16, Iss, Pp 101313-(2022)
Translational Oncology

مصطلحات موضوعية: Cancer Research, (MEK), mitogen-activated protein kinase, (RIP1), receptor-interacting protein 1, (MULE), MCL-1 ubiquitin ligase E3, (FOXO1), forkhead box protein O1, (RMS), rhabdomyosarcoma, (PI), propidium iodide, (ERK), extracellular signal-regulated kinase, (FN), PAX3/7-FOXO1 fusion-negative, (DUSP6), dual specificity phosphatase 6, (FGF), fibroblast growth factor, ERK1/2 signaling, hemic and lymphatic diseases, (PARP), poly(ADP-ribose) polymerase, Apoptotic cell death, (CI), combination index, neoplasms, (RTK), receptor tyrosine kinase, RC254-282, Original Research, (PAX), paired box, (CAM), chicken chorioallantoic membrane, (FP), PAX3/7-FOXO1 fusion-positive, Ulixertinib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, (IGF), insulin-like growth factor, RMS, (FCS), fetal calf serum, (Nec-1s), necrostatin-1s, (PBMCs), peripheral blood mononuclear cells, (CHX), cycloheximide, Oncology, (RSK), p90 ribosomal s6 kinase, S63845, (zVAD.fmk), N-benzyloxycarbonyl-Val-Ala-Asp(O-Me) fluoromethyl ketone, biological phenomena, cell phenomena, and immunity, (EV), empty vector

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9f914981a207a50fa9cf51a7b0aef2
http://www.sciencedirect.com/science/article/pii/S1936523321003041