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المؤلفون: Rohit R. Jadhav, Bin Hu, Zhongde Ye, Khushboo Sheth, Xuanying Li, William J. Greenleaf, Cornelia M. Weyand, Jörg J. Goronzy
المصدر: EBioMedicine
EBioMedicine, Vol 76, Iss, Pp 103825-(2022)مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Medicine (General), PsA, psoriatic arthritis, TF, transcription factor, vst, variance stabilized transformation), RA, rheumatoid arthritis, ATAC-seq, assay for transposase-accessible chromatin using sequencing, Regulatory Sequences, Nucleic Acid, General Biochemistry, Genetics and Molecular Biology, Arthritis, Rheumatoid, Epigenome, R5-920, CDAI, clinical disease activity index, SNP, single nucleotide polymorphisms, HC, healthy individuals, Humans, Rheumatoid arthritis, GREAT, genomic regions enrichment of annotations tool, MTX, methotrexate, GO, gene ontology, DA, differentially accessible, PBMCs, peripheral blood mononuclear cells, Chromatin accessibility, EM, effector memory, PCA, principal component analysis, General Medicine, Articles, DNA Methylation, CM, central memory, FACS, fluorescence activated cell sorting, TFBS, transcription factor binding site, SRA, sequence read archive, Chromatin, Super-enhancer, CRP, C-reactive protein, Medicine, qPCR, quantitative polymerase chain reaction, UMAP, uniform manifold approximation and projection, Susceptibility loci
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المؤلفون: Branka Horvat, Sergio Bernardini, Sandro Grelli, Vita Petrone, Massimo Andreoni, Antonella Minutolo, Vincenzo Malagnino, Hervé Perron, Paolo Di Francesco, Loredana Sarmati, Marco Iannetta, Benjamin Charvet, Enrico Garaci, Emanuela Balestrieri, Paola Sinibaldi Vallebona, Marta Zordan, Pietro Vitale, Claudia Matteucci, Marialaura Fanelli
المصدر: EBioMedicine, Vol 66, Iss, Pp 103341-(2021)
EBioMedicineمصطلحات موضوعية: Male, Medicine (General), medicine.medical_treatment, PT-INR, Prothrombin time international normalized ratio, Disease, Severity of Illness Index, Settore MED/07, TNFα, Tumor necrosis factor α, 0302 clinical medicine, EM, Effector memory, NK, Natural killer, Medicine, IL-6, Interleukin-16, HERVs, Human Endogenous Retroviruses, General Medicine, PBS, Phosphate-buffered saline, Interleukin 10, 030220 oncology & carcinogenesis, NC/VMKs, Nasal cannula or Venturi masks, Cytokines, Interleukin 17, Rho, Spearman correlation coefficient, MiP, Monolateral or minimal interstitial pneumonia, NIV, Non-invasive ventilation, Mononuclear, Pneumonia, Viral, CM, Central memory, CXCR1, C-X-C chemokine receptor type 1, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, R5-920, Gene Products, Humans, Aged, LDH, Lactate dehydrogenase, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, env, PT%, Prothrombin activity percentage, AS, Asymptomatic, Case-control study, Pneumonia, medicine.disease, PT, Prothrombin time, 030104 developmental biology, BiP/Bact, BiP with bacterial co-infection, Case-Control Studies, Immunology, Leukocytes, Mononuclear, 0301 basic medicine, CXCL6, C-X-C Motif chemokine ligand 6, viruses, T-Lymphocytes, OTI, Orotracheal intubation, Pregnancy Proteins, Cytokine storm, BiP, Bilateral interstitial pneumonia, PS, Paucisymptomatic, Leukocytes, Viral, TEM, Terminal effector memory, Respiratory outcome, qRT-PCR, Quantitative reverse-transcriptase PCR, biology, Sev, Severe, Cell Differentiation, Middle Aged, IL-10, Interleukin-10, Hospitalization, Cytokine, Treatment Outcome, CT, Computed tomography, Biomarker (medicine), MCP1, monocyte chemoattractant protein-1, Female, COVID-19, Human coronavirus disease 2019, Research Paper, C-PAP, Continuous Positive Airway Pressure, COV, SARS-CoV-2-positive individuals, DTT, Dithiothreitol, GUSβ, Beta-glucuronidase, HERV-W. human endogenous retroviruses, PTV, Policlinico Tor Vergata, T-cell exhaustion, IL-17, Interleukin-17, Interleukin 6, HERV-W ENV, Human Endogenous Retrovirus -W envelope, Inflammation, business.industry, Interleukin-6, Endogenous Retroviruses, COVID-19, Gene Products, env, P No, interstitial pneumonia, Settore MED/17, INFγ, Interferon γ, HD, Healthy donors, biology.protein, Mod, Moderate, Ct, Threshold cycle, IL-17RA, Interleukin-17 receptor A, PCR, Polymerase chain reaction, business