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المؤلفون: Hanna Yaroslavivna Stupnytska, Michael Ivanovich Sheremet, Yuliya Vyacheslavivna Bilooka, Vyacheslav Vasilievich Bilookyi, Oleksandr V. Bilookyi, Pharmacy, Bucharest, Romania, Yurii Yevgenovych Rogovyi, O.I. Fediv, Valentin Nicolae Varlas
المصدر: Journal of Medicine and Life
مصطلحات موضوعية: Modern medicine, medicine.medical_specialty, obesity, CP – ceruloplasmin, Fibrinogen, Systemic inflammation, Gastroenterology, Blood serum, Internal medicine, medicine, oxidative stress, Humans, IL-10 – interleukin-10, Irritable bowel syndrome, irritable bowel syndrome, Inflammation, CRP – C-reactive protein, TFNα – tumor necrosis factor-α, biology, TGFβ1 – transforming growth factor-β1, business.industry, Tumor Necrosis Factor-alpha, IBS – irritable bowel syndrome, General Medicine, medicine.disease, cytokines, Diarrhea, Limulus amebocyte lysate, IP – 8-isoprostane, biology.protein, Original Article, medicine.symptom, business, Ceruloplasmin, medicine.drug, endotoxicosis
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المؤلفون: Agnita J.W. Boon, Janneke G. Langendonk, L. Bossoni, Jacqueline Labra-Muñoz, Lena H.P. Vroegindeweij, J. H. Paul Wilson, Andrew G. Webb, Louise van der Weerd, Martina Huber, Marjolein Bulk
المساهمون: Internal Medicine, Neurology
المصدر: NeuroImage: Clinical, 30, 102657
NeuroImage: Clinical, 30:102657. Elsevier
NeuroImage: Clinical, Vol 30, Iss, Pp 102657-(2021)
NeuroImage: Clinical, 30. ELSEVIER SCI LTD
NeuroImage : Clinical
NeuroImage: Clinical, 30مصطلحات موضوعية: EPR, Electron Paramagnetic Resonance, Red nucleus, Cognitive Neuroscience, Iron, Computer applications to medicine. Medical informatics, Magnetometry, R858-859.7, 050105 experimental psychology, White matter, 03 medical and health sciences, 0302 clinical medicine, Nuclear magnetic resonance, SQUID, Superconducting Quantum Interference Device, Basal ganglia, medicine, Aceruloplasminemia, Humans, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, Post-mortem MRI, SIRM, Saturation Isothermal Remanent Magnetization, RC346-429, Temporal cortex, Ferritin, biology, Chemistry, ROI, Region of interest, 05 social sciences, Brain, Ceruloplasmin, Regular Article, Neurodegenerative Diseases, QSM, Quantitative Susceptibility Mapping, medicine.disease, NBIA, Neurodegeneration with Brain Iron Accumulation, Iron Metabolism Disorders, Magnetic Resonance Imaging, Dentate nucleus, medicine.anatomical_structure, Neurology, CP, ceruloplasmin, Hemosiderin, biology.protein, IRM, Isothermal Remanent Magnetization, Neurology (clinical), Neurology. Diseases of the nervous system, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Jeremy D. Semrau, Roman S. Polishchuk, Andreas E. Kremer, Bipin S. Baral, Claudia Einer, Christine von Toerne, Gerald Denk, Hans Zischka, Sabine Borchard, Tamara Rieder, Josef Lichtmannegger, Karl Heinz Weiss, Stefanie M. Hauck, Alan A. DiSpirito, Jennifer-Christin Müller, Uwe Karst, Elena V. Polishchuk, Carola Eberhagen, Ralf Wimmer, Christin Leitzinger, Frauke Neff, Simon Hohenester, Bastian Popper
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 3, Pp 571-596 (2019)
Cellular and Molecular Gastroenterology and Hepatology
Cell. Mol. Gast. Hept. 7, 571-596 (2019)مصطلحات موضوعية: Male, 0301 basic medicine, NADH, reduced nicotinamide adenine dinucleotide, Steatosis, Proteome, WD, Wilson disease, AST, aspartate aminotransferase, Mitochondrion, medicine.disease_cause, Cp, ceruloplasmin, F1FO, adenosine triphosphate synthase, 0302 clinical medicine, Hepatolenticular Degeneration, Medicine, Methanobactin, Original Research, Steatohepatitis, Liver injury, ND, normal diet, Gastroenterology, ICP, Inductively Coupled Plasma, Copper Chelation, Lipids, ddc, Mitochondria, Editorial, Liver, MB, methanobactin, Disease Progression, Female, 030211 gastroenterology & hepatology, HCD, high-calorie diet, medicine.medical_specialty, ATP, adenosine triphosphate, Normal diet, Acetyl-CoA, acetyl coenzyme A, HAI, Histologic Activity Index, Copper-storage Disease, Bile Acids and Salts, Excretion, 03 medical and health sciences, ROS, reactive oxygen species, Copper-Storage Disease, Internal medicine, Animals, TRIS, tris-(hydroxymethyl)aminomethane, lcsh:RC799-869, Inflammation, Hepatology, business.industry, CS, citrate synthase, medicine.disease, ADP, adenosine diphosphate, Diet, Rats, Fatty Liver, 030104 developmental biology, Endocrinology, MS, mass spectrometry, Copper-Transporting ATPases, Hepatocytes, BSA, bovine serum albumin, lcsh:Diseases of the digestive system. Gastroenterology, EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid, NAFLD, nonalcoholic fatty liver disease, Peptides, business, Copper, Oxidative stress, NAS, nonalcoholic fatty liver disease activity score
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0127ca524307588532a6af17ccfa54
http://www.sciencedirect.com/science/article/pii/S2352345X18301802 -
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المؤلفون: Kaori Okinaka, Goshi Shiota, Hiroyuki Oka, Tsuyoshi Yokobata, Shizuma Okazaki, Ikuya Noda, Minoru Morimoto, Noriko Itaba, Yohei Kono
المصدر: Regenerative Therapy, Vol 9, Iss, Pp 45-57 (2018)
Regenerative Therapyمصطلحات موضوعية: 0301 basic medicine, RBP4, retinol binding protein 4, AST, aspartate aminotransferase, GPX, glutathione peroxidase, DMSO, dimethyl sulfoxide, ChREBP, Carbohydrate-responsive element-binding protein, ERK, extracellular signal-regulated kinase, TRXR, thioredoxin reductase, CCl4, carbon tetrachloride, GSH, glutathione, HB-EGF, heparin binding-epidermal growth factor-like growth factor, GRX, glutaredoxin, GR, Glutathione reductase, IL-6, interleukin-6, NF-κB, nuclear factor-kappa B, Liver injury, lcsh:R5-920, Chemistry, lcsh:Cytology, STAT-3, Signal Tranducer and Activator of Transcription 3, Wnt signaling pathway, IL-1ra, interleukin-1 receptor antagonist, Liver regeneration, AREG, amphiregulin, HGFR, hepatocyte growth factor receptor, TRX, thioredoxin, medicine.anatomical_structure, A1AT, α1-antitrypsin, Hepatocyte, Original Article, C5aR, complement C5a receptor, lcsh:Medicine (General), mActb, mouse actin, beta, Hepatic cell sheets, PCNA, proliferating cell nuclear antigen, hGAPDH, human glyceraldehyde 3-phosphate dehydrogenase, Biomedical Engineering, TNFα, tumor necrosis factor alpha, Biomaterials, 03 medical and health sciences, 8-OHdG, 8-hydroxydeoxyguanosine, Downregulation and upregulation, ALT, alanine aminotransferase, SOD, superoxide dismutase, medicine, TGFα, transforming growth factor alpha, BM-MSCs, bone marrow-derived mesenchymal stem cells, lcsh:QH573-671, CBP, CREB-binding protein, Wnt/β-catenin signal inhibitor, MDA, malondialdehyde, ChoREs, carbohydrate response elements, Mesenchymal stem cell, C4A, complement C4A, medicine.disease, C3, complement C3, EGFR, epidermal growth factor receptor, TF, transferrin, PRX, peroxiredoxin, Transplantation, 030104 developmental biology, CP, ceruloplasmin, Hepatic stellate cell, Cancer research, Mesenchymal stem cells, APOE, apolipoprotein E, LXR, liver X receptor, Acute liver failure, Developmental Biology
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المؤلفون: Yan Wang, Yalin Wu, Zuguo Liu, Jingmeng Chen, Chao Chen
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, STEAP3, six-transmembrane epithelial antigen of prostate 3, genetic structures, STGD1, autosomal recessive Stargardt disease, TFRC, transferrin receptor, ONL, outer nuclear layer, Mitochondrion, medicine.disease_cause, Biochemistry, Photoreceptor cell, Mice, DMT1, Divalent metal transporter 1, GSH, glutathione, Stargardt Disease, oxidative stress, iron metabolism, AMD, age-related macular degeneration, IREB2, Iron-responsive element binding protein 2, POS, photoreceptor outer segments, chemistry.chemical_classification, Deferoxamine mesylate, LDH, lactate dehydrogenase, Chemistry, TEM, transmission electron microscope, lipid peroxidation, LED, light emitting diode, Cell biology, medicine.anatomical_structure, cell death, Retinaldehyde, Photoreceptor Cells, Vertebrate, Research Article, Programmed cell death, macular degeneration, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Animals, Ferroptosis, Molecular Biology, Reactive oxygen species, Retina, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, all-trans-retinal, photoreceptor, eye diseases, TF, transferrin, Mice, Inbred C57BL, 030104 developmental biology, CP, ceruloplasmin, atRAL, all-trans-retinal, H&E, hematoxylin and eosin, sense organs, FPN, Ferroportin, Reactive Oxygen Species, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212a
https://pubmed.ncbi.nlm.nih.gov/33334878 -
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المؤلفون: Ashley I. Bush, Scott Ayton, Peng Lei
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, ZnT, Zinc transporter, NAC, N-acetylcysteine, SOD1, superoxide dismutase 1, Plaque, Amyloid, HO-1, heme oxygenase 1, Disease, CSF, cerebrospinal fluid, Biochemistry, Cp, ceruloplasmin, LTP, long-term potentiation, Amyloid precursor protein, clioquinol, PUFA, polyunsaturated fatty acids, ApoE, apolipoprotein E, DFO, deferoxamine, biology, zinc, Brain, FAD, familial AD, PBT2, GPx4, glutathione peroxidase 4, Alzheimer's disease, Alzheimer’s disease, RTA, radical trapping agent, Aβ, amyloid-β peptide, Iron, Reviews, ZIP, Zinc regulated transporter-like Iron regulated transporter-like Protein, Neuropathology, AD, Alzheimer’s disease, Selenium, 03 medical and health sciences, Neurochemical, Alzheimer Disease, medicine, Animals, Ferroptosis, Humans, Dementia, Molecular Biology, APP, amyloid protein precursor, NMDA, N-methyl-D-aspartate, 030102 biochemistry & molecular biology, business.industry, PBT2, 5,7-dichloro-2-[(dimethylamino)methyl]quinolin-8-ol, Cell Biology, Phospholipid Hydroperoxide Glutathione Peroxidase, medicine.disease, QSM, quantitative susceptibility mapping, 030104 developmental biology, copper, biology.protein, business, MRI, magnetic resonance imaging, Neuroscience
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e04007722ed5b78b56b5996523ffd2
https://doi.org/10.1074/jbc.rev120.008207 -
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المؤلفون: Yan Lu, Gregory J. Anderson, Pavle Matak, Huijun Chen, Sarah J. Wilkins, Scott C. Kogan, Deepak Darshan, Brie K. Fuqua, Alex Loguinov, Chris D. Vulpe, Linda A. Dunn, Joshua L. Dunaief, David M. Frazer
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 405-427 (2018)
Cellular and molecular gastroenterology and hepatology, vol 6, iss 4مصطلحات موضوعية: mice lacking CP in the whole body, Male, Hephaestin, Hephfl/flCp, polymerase chain reaction, 3′-diaminobenzidine, Mice, 0302 clinical medicine, PCR, polymerase chain reaction, Homeostasis, PBS, Original Research, Hephsla/slaCp-/-, mice lacking CP in the whole body and expressing only the sla mutant form of HEPH, chemistry.chemical_classification, HCI, TBST, Cp-/-, mice lacking CP in the whole body, WT, HEPH, hephaestin, Gastroenterology, HCI, hydrochloric acid, GI, gastrointestinal, GI, 3. Good health, Absorption, Physiological, mice lacking CP in the whole body and expressing only the sla mutant form of HEPH, PCR, Editorial, Organ Specificity, mice lacking HEPH in the intestine alone, Hephint/intCp-/-, mice lacking HEPH in the intestine alone and lacking CP in the whole body, standard deviation, Iron Overload, Intestinal Iron Absorption, FDR, false discovery rate, Anemia, Duodenum, Knockout, Physiological, TIBC, 03 medical and health sciences, Hephfl/flCp-/-, mice with floxed Heph alleles and lacking CP in the whole body, Hephsla/slaCp, Hephint/int, mice lacking HEPH in the intestine alone, total iron binding capacity, mice with floxed Heph alleles, Iron Deficiency Anemia, Ligation, Tris-buffered saline with 0.1% Tween-20, SD, NTBI, TBST, Tris-buffered saline with 0.1% Tween-20, Animal, Cp, MCF, multicopper ferroxidase, mice with floxed Heph alleles and lacking CP in the whole body, medicine.disease, gastrointestinal, WT, wild-type, TF, transferrin, Mice, Inbred C57BL, 030104 developmental biology, Enterocytes, chemistry, Iron-deficiency anemia, CP, ceruloplasmin, NTBI, non-transferrin bound iron, Ceruloplasmin, mice lacking HEPH in the intestine alone and lacking CP in the whole body, 030217 neurology & neurosurgery, Non-Transferrin Bound Iron, 0301 basic medicine, hydrochloric acid, Inbred C57BL, HEPH, double-knockout mice lacking both HEPH and CP, Heph-/-, mice lacking HEPH in the whole body, Body Size, sla, Cation Transport Proteins, Mice, Knockout, multicopper ferroxidase, biology, medicine.diagnostic_test, Heph-/-Cp-/- or DKO, double-knockout mice lacking both HEPH and CP, Heph, Animals, Suckling, Phenotype, CP, Serum iron, Female, FPN1, ferroportin 1, Oxidation-Reduction, TF, sex-linked anemia, hephaestin, FPN1, Hephint/intCp, Iron, PBS, phosphate-buffered saline, phosphate-buffered saline, sla, sex-linked anemia, Absorption, FDR, non-transferrin bound iron, medicine, DAB, Animals, transferrin, mice lacking HEPH in the whole body, Suckling, Hephfl/fl, lcsh:RC799-869, wild-type, MCF, Hepatology, DAB, 3,3′-diaminobenzidine, TIBC, total iron binding capacity, Body Weight, Membrane Proteins, Metabolism, ferroportin 1, Molecular biology, Disease Models, Animal, Transferrin, Disease Models, biology.protein, Hephint/int, lcsh:Diseases of the digestive system. Gastroenterology, false discovery rate, Heph-/-Cp-/- or DKO, Hephfl/fl, mice with floxed Heph alleles, SD, standard deviation
وصف الملف: application/pdf
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المؤلفون: Sabine Feichtenhofer, Peter M. Abuja, Judith S. Fabjan
المصدر: FEBS Letters. 501:42-46
مصطلحات موضوعية: Male, Lipid Peroxides, Reaction mechanism, Lipid peroxidation, Biophysics, Redox cycle, Ascorbic Acid, Biochemistry, Antioxidants, chemistry.chemical_compound, Structural Biology, Genetics, Humans, Vitamin E, Molecular Biology, Oxidase test, biology, Low-density lipoprotein, Ceruloplasmin, Water, CP - Ceruloplasmin, Cell Biology, Atherosclerosis, Dehydroascorbic Acid, Enzyme Activation, Lipoproteins, LDL, Plasma antioxidant, Solubility, chemistry, Reducing Agents, biology.protein, Female, lipids (amino acids, peptides, and proteins), Oxidation-Reduction, Copper, 15-Lipoxygenase, Oxidation rate
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المؤلفون: Maud E. S. Achard, Sian L. Stafford, Alastair G. McEwan, Ronan Kapetanovic, Nilesh J. Bokil, Matthew J. Sweet, Mark A. Schembri
المصدر: Bioscience Reports, Vol 33, Iss 4, p e00049 (2013)
Scopus-Elsevier
Bioscience Reportsمصطلحات موضوعية: PDE, phosphodiesterase, lcsh:Life, lcsh:QR1-502, Review Article, Nrf2, nuclear factor-erythroid 2-related factor 2, TNF, tumour necrosis factor, Biochemistry, lcsh:Microbiology, 0302 clinical medicine, DC, dendritic cells, Macrophage, Cation Transport Proteins, innate immunity, IKKβ, IκB (inhibitor of nuclear factor κB) kinase β, 0303 health sciences, Toll-like receptor, Bacterial Infections, Antimicrobial, 3. Good health, MMP, matrix metalloproteinase, Zinc, CTR, copper transporter, monocyte, copper transporter (CTR), LPS, lipopolysaccharide, NF-κB, nuclear factor κB, FPN1, ferroportin 1, TLR, Toll-like receptor, GPI, glycosylphosphatidylinositol, Biochemistry & Molecular Biology, host defence, zinc transporter, Biophysics, IFNγ, interferon γ, chemistry.chemical_element, Biology, S3, 03 medical and health sciences, ROS, reactive oxygen species, Immune system, Immunity, SOD, superoxide dismutase, Animals, Humans, Molecular Biology, 030304 developmental biology, TRIF, TIR (Toll/interleukin-1 receptor) domain-containing adaptor protein inducing interferon β, Innate immune system, Macrophages, Transporter, Biological Transport, Cell Biology, MT, metallothionein, Immunity, Innate, IL, interleukin, lcsh:QH501-531, chemistry, Gene Expression Regulation, CP, ceruloplasmin, Dietary Supplements, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery, Copper
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867cebb3d5a32f9e9bb61fd2445ba627
http://www.bioscirep.org/bsr/033/e049/bsr033e049.htm -
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المؤلفون: Anirban Basu, Susan J. Vannucci, Jaimie L Myrkalo, Sandra J. Hewett, Ellora Sen, Tracy F. Uliasz, Steven W. Levison, Lisa B. Willing
المصدر: ASN NEURO
ASN Neuro, Vol 3 (2011)مصطلحات موضوعية: IL-1, interleukin-1, Excitotoxicity, HBSS, Hepes-buffered salt solution, MCT-1, monocarboxylate transporter-1, medicine.disease_cause, GS, glutamine synthetase, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide, 0302 clinical medicine, P6, postnatal day 6, Hypoxia, Ischemic Preconditioning, Cells, Cultured, Neurons, 0303 health sciences, DMEM, Dulbecco's modified Eagle's medium, dbcAMP, dibutyryl-cAMP, LDH, lactate dehydrogenase, General Neuroscience, Glutamate receptor, glutamine synthetase, EAAT-1, excitatory amino acid transporter-1, Cell Differentiation, stroke, Cell biology, Excitatory Amino Acid Transporter 1, medicine.anatomical_structure, cell death, Neuroprotective Agents, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, transporter, Excitatory postsynaptic potential, medicine.symptom, excitotoxicity, Astrocyte, Research Article, Programmed cell death, H/I, hypoxia–ischaemia, Glutamic Acid, glutamate, Biology, S3, CNS, central nervous system, Neuroprotection, S2, S5, lcsh:RC321-571, 03 medical and health sciences, Glutamate-Ammonia Ligase, Glutamine synthetase, Glial Fibrillary Acidic Protein, medicine, Animals, Rats, Wistar, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, 030304 developmental biology, GFAP, glial fibrillary acidic protein, Hypoxia (medical), Rats, TBS, Tris-buffered saline, nervous system, Animals, Newborn, CP, ceruloplasmin, Astrocytes, Neurology (clinical), Neuroscience, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d983a274e491e853641dea2c33bcca0a
http://europepmc.org/articles/PMC3153963