المؤلفون: Joanna Brzeszczyńska, Filip Brzeszczyński, Kay Samuel, Katie Morgan, Steven D. Morley, John N. Plevris, Peter C. Hayes

المصدر: Cells, Vol 9, Iss 3, p 770 (2020)

مصطلحات موضوعية: reference genes (rg), heparg cells, apap (acetaminophen), cpz (chlorpromazine), Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/3/770; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/6561e562b8a14fc7afe63fc243209f5c

المؤلفون: Richard B. Sessions, Erik J. B. Landin, Nahida Akter, Christina Redfield, Sara A. Ryan, Richard J. K. Taylor, Matthew P. Crump, Neesha Dedi, Alice J. Bochel, Christopher Williams

المصدر: Landin, E J B, Williams, C, Ryan, S A, Bochel, A, Akter, N, Redfield, C, Sessions, R B, Dedi, N, Taylor, R J & Crump, M P 2021, ' The structural basis for high affinity binding of α1-acid glycoprotein to the potent antitumor compound UCN-01 ', Journal of Biological Chemistry, vol. 297, no. 6, 101392 . https://doi.org/10.1016/j.jbc.2021.101392
The Journal of Biological Chemistry

مصطلحات موضوعية: glycoprotein, UCN-01, Conformational change, Kinase Inhibitors, Orosomucoid, Antineoplastic Agents, BrisSynBio, TROSY-HSQC, transverse relaxation optimized - heteronuclear single quantum coherence spectroscopy, Crystallography, X-Ray, Biochemistry, AGP2-FL, full-length AGP2, DSP, disopyramide, AGP, alpha-1-acid glycoprotein, Protein Domains, Cyclin-dependent kinase, CDK2, cyclin dependent kinases, medicine, Chk1, Checkpoint 1, otorhinolaryngologic diseases, Staurosporine, kinase inhibitors, Humans, CPZ, chlorpromazine, Molecular Biology, X-ray crystallography, chemistry.chemical_classification, AGP2, biology, Chemistry, Kinase, Cyclin-dependent kinase 2, Bristol BioDesign Institute, Cell Biology, AMT, amitriptyline, Small molecule, biology.protein, pharmokinetics, Glycoprotein, medicine.drug, Research Article, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d08145bb2d4a71698152ed8ac9dcfb9
https://research-information.bris.ac.uk/en/publications/3354a1b7-e4f5-45d1-b9d6-ce2255c2e8e9

المؤلفون: Ima Trempler, Udo Dannlowski, Isabel Standke, Rebekka Lencer, Ricarda Ines Schubotz

المصدر: NeuroImage : Clinical
NeuroImage: Clinical, Vol 32, Iss, Pp 102855-(2021)

مصطلحات موضوعية: RT, reaction time, Hippocampus, BACS, Brief Assessment of Cognition in Schizophrenia (Keefe et al., 2004), Gating, CPZ, chlorpromazine equivalents (Andreasen et al., 2010), Lateral prefrontal cortex, Cognition, Striatal gating, Pr, discrimination index, medicine.diagnostic_test, Dri, drifts, Cognitive flexibility, CR, correct rejections of drifts, Regular Article, SANS, Scale for the Assessment of Negative Symptoms (Andreasen, 1984b), Magnetic Resonance Imaging, Distractor shielding, Frontal Lobe, medicine.anatomical_structure, Neurology, Br, response bias, psychological phenomena and processes, SAPS, Scale for the Assessment of Positive Symptoms (Andreasen, 1984a), Cognitive Neuroscience, Computer applications to medicine. Medical informatics, R858-859.7, Prefrontal Cortex, behavioral disciplines and activities, FA, false alarms at drifts, BDI-II, Becks Depression Inventory-II (Beck et al., 1996), medicine, Humans, Radiology, Nuclear Medicine and imaging, RC346-429, Anterior cingulate cortex, Swi, switches, Neural correlates of consciousness, business.industry, Medial prefrontal cortex, H, hits at switches, Prediction error processing, NSS, Heidelberg Scale for Neurological Soft Signs (Schröder et al., 1991), nervous system, Rule switching, BIS, Baratt Impulsiveness Scale (Patton et al., 1995), M, misses of switches, Schizophrenia, Neurology (clinical), Neurology. Diseases of the nervous system, business, Functional magnetic resonance imaging, MC, motor control, SD, standard deviation, Cognition Disorders, Insula, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b767cf8a829f894af8365374f859de2
http://europepmc.org/articles/PMC8551223

المؤلفون: Yue-Hong Zhao, Longwei Bai, Hao Li, Qun Wang, Yukai Qin, Weikang Sun, Wei-Wei Li

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, EspIgR, E. sinensis polymeric immunoglobulin receptor, Hemocytes, Von Willebrand factor type D domain, invertebrate immunology, Biochemistry, Bacterial Adhesion, Vitellogenins, Crustacea, Phylogeny, NJ, neighbor-joining, polymeric immunoglobulin receptor (pIgR), Cell biology, LB, Luria–Bertani, Research Article, hemocyte, Protein domain, pIg, polyimmunoglobulin, Biology, 03 medical and health sciences, Vitellogenin, ORF, open reading frame, Phagocytosis, Protein Domains, pIgR, polymeric immunoglobulin receptor, vitellogenin (Vg), Animals, Humans, CPZ, chlorpromazine, Amino Acid Sequence, Molecular Biology, Vg, vitellogenin, Innate immune system, 030102 biochemistry & molecular biology, Bacteria, Base Sequence, HEK 293 cells, VWD, von Willebrand factor type D domain, bacterial infection, Cell Biology, TBS, Tris-buffered saline, Open reading frame, 030104 developmental biology, HEK293 Cells, biology.protein, LLTP, large lipid transfer protein, SC, secretory component, Polymeric immunoglobulin receptor, IPTG, isopropyl b-D-1-thiogalactopyranoside, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b69112c835784b4a8c06d735ed793
http://europepmc.org/articles/PMC7949091

المؤلفون: Shuangshuang Ji, Hao Fei, Xiaolong Chen, Hanjie Liu, Ang Li

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: conformation, Conformational change, LAMP-1, lysosomal-associated membrane protein 1, Peptide, CMP-Neu5Ac, cytidine 5′-monophospho-N-acetylneuraminic acid, ANS-Na, sodium 8-Anilino-1-naphthalenesulfonate, Biochemistry, 3Fax-Neu5Ac, 3Fax-Peracetyl Neu5Ac, Cell membrane, Gly-lit, glycolithocholic acid, anion sensitivity, chemistry.chemical_classification, IgG, Immunoglobulin G, Chemistry, BafA1, bafilomycin A1, CPP, cell-penetrating peptides, CAPs, cationic amphipathic peptides, Peptide Conformation, medicine.anatomical_structure, Membrane, TFE, 2,2,2-trifluoroethanol, FITC, fluorescein isothiocyanate, Hydrophobic and Hydrophilic Interactions, Research Article, IC50, the half inhibitory concentration, Anions, LAMP-2, lysosomal-associated membrane protein 2, cationic amphipathic peptides, CLSM, confocal laser scanning microscope, Endosomes, NY, nystatin, PI, propidium iodide, PBS, phosphate buffer saline, EIPA, amiloride, LUVs, large unilamellar vesicles, SAP, saporin, Amphiphile, medicine, Membrane activity, Amino Acid Sequence, CPZ, chlorpromazine, Molecular Biology, IC20, the 20% inhibitory concentration, hydrophobicity, endosomolytic delivery, Cell Membrane, Cell Biology, Lysosomal-Associated Membrane Protein 1, PSA, polysialic acid, GRAVY, the grand average of hydropathy, Biophysics, LC50, the half leakage concentration, DOPC, dioleoyl phosphatidylcholine, Peptides, DOPG, dioleoyl phosphatidylglycerole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e5bcc1c77a58618c41d844f8e23287
https://doi.org/10.1016/j.jbc.2021.101364

المؤلفون: Katie Morgan, Steven D. Morley, Peter C. Hayes, Joanna Brzeszczynska, Kay Samuel, Filip Brzeszczyński, John N. Plevris

المصدر: Brzeszczyńska, J, Brzeszczyński, F, Samuel, K, Morgan, K, Morley, S D, Plevris, J N & Hayes, P C 2020, ' Validation of Reference Genes for Gene Expression Studies by RT-qPCR in HepaRG Cells during Toxicity Testing and Disease Modelling ', Cells, vol. 9, no. 3 . https://doi.org/10.3390/cells9030770
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 770 (2020)

مصطلحات موضوعية: Transcription, Genetic, Cell Survival, Chlorpromazine, APAP (Acetaminophen), CPZ (Chlorpromazine), Computational biology, Real-Time Polymerase Chain Reaction, Models, Biological, Article, Reference Genes (RG), Cell Line, law.invention, Adenosine Triphosphate, law, Transcription (biology), Reference genes, Toxicity Tests, Gene expression, Humans, Disease, RNA, Messenger, lcsh:QH301-705.5, Gene, Polymerase chain reaction, Glyceraldehyde 3-phosphate dehydrogenase, Acetaminophen, Genes, Essential, biology, General Medicine, Reference Standards, Phenotype, Housekeeping gene, lcsh:Biology (General), Gene Expression Regulation, HepaRG cells, biology.protein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ecd128f5a0e4db57c46fb83748e4a8
https://www.pure.ed.ac.uk/ws/files/142979118/cells_09_00770_v2.pdf

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المؤلفون: Jean Paul Briand, Nicolas Page, Sylviane Muller, Christophe Macri, Nicolas Schall, Ana Maria Cuervo, Inmaculada Tasset, Fengjuan Wang

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Immunopathologie et chimie thérapeutique (ICT), Institut de biologie moléculaire et cellulaire (IBMC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Autophagy
Autophagy, Taylor & Francis, 2015, 11 (3), pp.472-486. ⟨10.1080/15548627.2015.1017179⟩

مصطلحات موضوعية: Phosphopeptides, Mice, Inbred MRL lpr, LC-MS, liquid chromatography-mass spectrometry, NBD, nucleotide binding domain, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, T-Lymphocytes, Autoimmunity, CPZ: chlorpromazine, SLE, systemic lupus erythematosus, chemistry.chemical_compound, Mice, Chaperone-mediated autophagy, paraquat, 1, 1′-dimethyl-4, 4′-bipyridyldinium dichloride, qRT-PCR, quantitative reverse transcriptase-polymerase chain reaction, immune system diseases, Serine, Lupus Erythematosus, Systemic, antigen-presenting cells, ALF, artificial lysosomal fluid, RPL5, ribosomal protein L5, Phosphorylation, skin and connective tissue diseases, chaperone-mediated autophagy, HSPA8/HSC70, education.field_of_study, B-Lymphocytes, SBD, substrate binding domain, Sciences du Vivant [q-bio]/Biotechnologies, ELISA, enzyme-linked immunosorbent assay, MHCII, major histocompatibility complex class II, class II MHC molecules, Endocytosis, Basic Research Paper, CMA, chaperone-mediated autophagy, Cell biology, Lysosomal lumen, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, bodipy: BODIPY FL C5 Lactosylceramide/bovine serum albumin, LAMP2A, lysosomal-associated membrane protein 2A, RP-HPLC, reversed-phase high-performance liquid chromatography, autophagy, CTSD, cathepsin D, PBS, phosphate-buffered saline, Endosomes, Biology, SEM, standard error of the mean, Ribosomal protein L5, Ribonucleoprotein, U1 Small Nuclear, lysosomal chaperones, TFA, trifluoroacetic acid, Sequestosome 1, lysosomes, CoIP, coimmunoprecipitation, Downregulation and upregulation, Animals, Humans, education, Antigen-presenting cell, Molecular Biology, SQSTM1/p62, sequestosome 1, iv, intravenous, SNRNP70/U170K: small nuclear ribonucleoprotein 70kDa, Autophagy, HSC70 Heat-Shock Proteins, Histocompatibility Antigens Class II, Cell Biology, lupus, HCQ, hydroxychloroquine, LC3-II, MAP1LC3-II, Molecular biology, Peptide Fragments, TF, transferrin, chemistry, APC, antigen-presenting cell, Phosphoserine, heat shock proteins, NIH 3T3 Cells, FCS, fetal calf serum, SD, standard deviation, DAPI, 4′, 6-diamidino-2-phenylindole, Molecular Chaperones, B lymphocytes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3852162ef8e4c9b772246960eadd1b
https://hal.archives-ouvertes.fr/hal-02988901

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تسجيل الدخول للوصول الكامل.