-
1دورية أكاديمية
المؤلفون: Ma, Hao, Ou, Zhi-lin, Alaeiilkhchi, Nima, Cheng, Yong-quan, Chen, Kai, Chen, Jia-yu, Guo, Ru-qin, He, Min-yue, Tang, Shi-yi, Zhang, Xin, Huang, Zhi-ping, Liu, Junhao, Liu, Jie, Zhu, Qing-an, Huang, Zu-chengAff1, IDs1294402402185y_cor15, Jiang, HuiAff1, IDs1294402402185y_cor16
المصدر: Lipids in Health and Disease. 23(1)
-
2دورية أكاديمية
المؤلفون: Hao Ma, Zhi-lin Ou, Nima Alaeiilkhchi, Yong-quan Cheng, Kai Chen, Jia-yu Chen, Ru-qin Guo, Min-yue He, Shi-yi Tang, Xin Zhang, Zhi-ping Huang, Junhao Liu, Jie Liu, Qing-an Zhu, Zu-cheng Huang, Hui Jiang
المصدر: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-16 (2024)
مصطلحات موضوعية: Demyelination, MiR-223, Lipid droplets, Lipophagy, Microglia, CTSB (cathepsin B), Nutritional diseases. Deficiency diseases, RC620-627
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1476-511X
-
3
المؤلفون: Po Hu, Hongzheng Wang, Xiaoxuan Yu, Wenzhuo Sun, Hui Hui, Hui Li, Mengyuan Zhu, Zhanyu Wang, Jingyan Xu, Qinglong Guo, Yingjie Qing
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3178-3192 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: NPC, Niemann-Pick type disease C, Cathepsin D, ATG, autophagy related, NH4Cl, ammonium chloride, Lysosomal damage, Calcium in biology, Hematological malignancies, 0302 clinical medicine, RAB7A, RAS-related protein RAB-7a, K48, lysine 48, LC3, microtubule-associated protein 1 light chain 3, TFEB, transcription factor EB, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, RT-qPCR, real time quantitative PCR, Chemistry, LCD, lysosome-dependent cell death, CaN, calcineurin, P62/SQSTM1, sequestosome 1, Cell biology, TRPML1, transient receptor potential mucolipin 1, medicine.anatomical_structure, Cholesterol, 030220 oncology & carcinogenesis, shRNA, short hairpin RNA, Original Article, CsA, cyclosporine A, DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride, Programmed cell death, AO, acridine orange, CTSD, cathepsin D, LW-218, PBS, phosphate-buffered saline, CTSB, cathepsin B, LMP, lysosome membrane permeabilization, EGTA, ethylene glycol-bis(2-aminoethyl ether)-N,N,N′,N′-tetraacetic acid, RM1-950, Lysosome-dependent cell death, 03 medical and health sciences, Dex, dexamethasone, ROS, reactive oxygen species, FBS, fetal bovine serum, Lysosome, NPC1, NPC intracellular cholesterol transporter 1, medicine, BAF A1, bafilomycin A1, 030304 developmental biology, Cathepsin, PBMCs, peripheral blood mononuclear cells, Lysosomal membrane permeabilization, K63, lysine 63, Cell growth, DCFH-DA, 2,7-dichlorodi-hydrofluorescein diacetate, Autophagy, BID, BH3-interacting domain death agonist, Lysophagy, OD, optical density, TFEB, CCK8, Cell Counting Kit, Therapeutics. Pharmacology, LAMPs, lysosomal-associated membrane proteins
-
4
المؤلفون: Jane A. Mitchell, Ricky Vaja, Blerina Ahmetaj-Shala, Nicholas S. Kirkby, Peter M. George, Santosh S. Atanur
المساهمون: British Heart Foundation
المصدر: JACC: Basic to Translational Science
مصطلحات موضوعية: 0301 basic medicine, Cardiac & Cardiovascular Systems, Endothelium, ACE2, CTSB, cathepsin B, Inflammation, 030204 cardiovascular system & hematology, medicine.disease_cause, PPIA, peptidylprolyl isomerase A, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, INFLAMMATION, INFECTION, medicine, ADAM17, ADAM metallopeptidase domain 17, Respiratory system, 1102 Cardiorespiratory Medicine and Haematology, PPIB, peptidylprolyl isomerase B, Coronavirus, Peptidylprolyl isomerase, Science & Technology, ACE2, angiotensin converting enzyme 2, COVID-19, coronavirus disease-2019, business.industry, cardiovascular, GTEx, Genotype-Tissue Expression, SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2, COVID-19, 1103 Clinical Sciences, BSG, basigin, endothelial cells, Epithelium, CTSL, cathepsin L, 030104 developmental biology, medicine.anatomical_structure, age, PBMC, peripheral blood mononuclear cells, Basigin, Immunology, Cardiovascular System & Cardiology, CD147, TMPRSS2, transmembrane serine protease 2, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Life Sciences & Biomedicine, SYSTEM
-
5
المؤلفون: Charles Nicaise, Kevin Willemart, Florian Poulain, Nicolas Gillet, Noémie Avalosse, Riselane Lotfi, Jacques Gilloteaux, Noelle Ninanne, Noémie Lejeune, Kathleen De Swert, Valery Bielarz
المصدر: Brain Research
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, viruses, Cell, Neuroblastoma, 0302 clinical medicine, RA, retinoic acid, tmprss2, transmembrane protease, serine 2, BBB, blood–brain barrier, Cytopathic effect, COVID-19, coronavirus disease 2019, ctsb, cathepsin B, General Neuroscience, Serine Endopeptidases, ish, in situ hybridization, medicine.anatomical_structure, Neurotropism, Angiotensin-Converting Enzyme 2, Cell type, SARS-CoV, severe acute respiratory syndrome coronavirus, Clinical Neurology, Biology, Models, Biological, Article, ctsl, cathepsin L, MOI, multiplicity-of-infection, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, medicine, Humans, Molecular Biology, Tropism, hprt, hypoxanthine–guanine phosphoribosyltransferase, SARS-CoV-2, ace2, angiotensin-converting enzyme 2, COVID-19, medicine.disease, Molecular biology, 030104 developmental biology, Cell culture, Susceptibility, Vero cell, Neurology (clinical), Glioblastoma, 030217 neurology & neurosurgery, SARS-CoV-2, severe acute respiratory syndrome coronavirus-2, Developmental Biology
وصف الملف: application/pdf
-
6
المؤلفون: Gregor J. Kocher, Elias D. Bührer, Yanyun Gao, Laurène Froment, Sean R R Hall, Adrian F. Ochsenbein, Carsten Riether, Colin Tièche, Rémy Bruggmann, Ralph A. Schmid, Stefan Weis, Primo Schär, Kurt Wyler, Nina Hobi, Michael A. Amrein, Sabina Berezowska, Thomas M. Marti, Ren-Wang Peng, Patrick Dorn
المصدر: Neoplasia (New York, N.Y.)
Tièche, Colin; Gao, Yanyun; Bührer, Elias; Hobi, Nina; Berezowska, Sabina Anna; Wyler, Kurt; Froment, Laurène; Weis, Stefan; Peng, Ren-Wang; Bruggmann, Rémy; Schär, Primo; Amrein, Michael Alex; Hall, Sean; Dorn, Patrick; Kocher, Gregor; Riether, Carsten; Ochsenbein, Adrian; Schmid, Ralph; Marti, Thomas (2019). Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549. Neoplasia, 21(2), pp. 185-196. Elsevier 10.1016/j.neo.2018.09.008 <http://dx.doi.org/10.1016/j.neo.2018.09.008>
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 2, Pp 185-196 (2019)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, Tumor initiation, POU5F1, OCT4, TIC, tumor initiation cell, Receptor tyrosine kinase, SNAI1, SNAIL, Mice, 0302 clinical medicine, CDH1, E-cadherin, SCLC, small cell lung cancer, Carcinoma, Non-Small-Cell Lung, 540 Chemistry, MYC, cellular Myc, MMP2, matrix metalloproteinase-2, 610 Medicine & health, MYCN, N-Myc, SOX2+, high SOX2, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, NSCLC, non–small cell lung cancers, Phenotype, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, DNA methylation, Neoplastic Stem Cells, GOseq, KEGG pathway enrichment analysis, medicine.drug, Original article, Epithelial-Mesenchymal Transition, CSCs, cancer stem cells, ALCAM, CD166, hybrid-E/M, hybrid epithelial/mesenchymal, Biology, SNAI2, SLUG, lcsh:RC254-282, Immunophenotyping, CDH17, Cadherin 17, CTSB, Cathepsin B, 03 medical and health sciences, Cancer stem cell, Cell Line, Tumor, medicine, Animals, Humans, Epigenetics, Cell Proliferation, Cisplatin, VIM, Vimentin, CD90−, low CD90 expression, Gene Expression Profiling, DNA Methylation, EGFR, epidermal growth factor receptor, Disease Models, Animal, 030104 developmental biology, A549 Cells, Cell culture, Cancer research, biology.protein, 570 Life sciences, biology, IR, ionizing radiation, Transcriptome, Biomarkers, EMT, epithelial-to-mesenchymal transition, DNA Damage
وصف الملف: application/pdf
-
7
المؤلفون: Anthony P. Davenport, H. Llewelyn Roderick, Emma L. Robinson, Kanar Alkass, Janet J. Maguire, Olaf Bergmann
المساهمون: Cardiologie, RS: Carim - H02 Cardiomyopathy, Maguire, Janet [0000-0002-9254-7040], Davenport, Anthony [0000-0002-2096-3117], Apollo - University of Cambridge Repository
المصدر: Journal of Molecular and Cellular Cardiology, 147, 88-91. ELSEVIER SCI LTD
Journal of Molecular and Cellular Cardiologyمصطلحات موضوعية: 0301 basic medicine, Aging, Cathepsin L, ACE, angiotensin I converting enzyme, Disease, 030204 cardiovascular system & hematology, BDKRB2, bradykinin receptor B2, ComputingMethodologies_ARTIFICIALINTELLIGENCE, Cathepsin B, Angiotensin, 0302 clinical medicine, Interferon, MAS1, MAS1 proto-oncogene G protein-coupled receptor, Medicine, TMPRSS11D, transmembrane protease serine 11D, Myocytes, Cardiac, TMPRSS2, transmembrane protease serine 2, Young adult, Furin, IFNAR1, interferon (alpha beta and omega) receptor 1, biology, Serine Endopeptidases, Interleukin, AGTR1, angiotensin II receptor type 1, Apelin, BDKRB1, bradykinin receptor B1, apelin, Interferon gamma receptor 1, TMPRSS11E, transmembrane protease serine 11E, Angiotensin-Converting Enzyme 2, Cardiology and Cardiovascular Medicine, Coronavirus Infections, medicine.drug, Angiotensins, InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, Pneumonia, Viral, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, RNA-sequencing, CTSB, cathepsin B, Virus Attachment, APLNR, apelin receptor, IRF1, interferon regulatory factor 1 (regulates transcription of interferons), Peptidyl-Dipeptidase A, Bradykinin, FURIN, furin (paired basic amino acid cleaving enzyme), TMPRSS2, Article, 03 medical and health sciences, Betacoronavirus, Downregulation and upregulation, Humans, ADAM17, ADAM metallopeptidase domain 17, IL6R, interleukin 6 receptor, Molecular Biology, Pandemics, Gene, ComputingMethodologies_COMPUTERGRAPHICS, SLC6A19, solute carrier family 6 (neutral amino acid transporter) member 19 (aka B0AT1), SARS-CoV-2, business.industry, Myocardium, human cardiomyocytes, IFNAR2, interferon (alpha beta and omega) receptor 2 (IFNAR1and 2 form chains for interferons alpha and beta), COVID-19, Virus Internalization, angiotensin, CTSL, cathepsin L, ComputingMethodologies_PATTERNRECOGNITION, 030104 developmental biology, Immunology, biology.protein, IFNGR1, Interferon gamma receptor 1, Human cardiomyocytes, ACE2, angiotensin I converting enzyme 2, business
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; Print-Electronic
-
8
المؤلفون: Qianjin Liu, Ying Miao, Xin Zuo, Rongbin Zhou, Ping Zheng, Ling-Yan Su, Chunli Sun, Min Xu, Rongcan Luo, Tian Xue, Yong-Gang Yao, Lijin Jiao, Wei Xiong
المصدر: Redox Biology, Vol 34, Iss, Pp 101560-(2020)
Redox Biologyمصطلحات موضوعية: WT, wild type, 0301 basic medicine, Inflammasomes, Clinical Biochemistry, Pharmacology, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, NLRP3, NOD-like receptor protein 3, Mice, PFC, prefrontal cortex, 0302 clinical medicine, siNlrp3, Nlrp3 siRNA, Analgesic tolerance, lcsh:QH301-705.5, Melatonin, Analgesics, lcsh:R5-920, LDH, lactate dehydrogenase, Microglia, Morphine, Chronic pain, Inflammasome, ELISA, enzyme-linked immunosorbent assay, medicine.anatomical_structure, Nociception, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, Hyperalgesia, LPS, lipopolysaccharide, IL-1β, Interleukin 1β, medicine.symptom, lcsh:Medicine (General), Research Paper, medicine.drug, siNC, negative control siRNA, Analgesic, PBS, phosphate-buffered saline, CTSB, cathepsin B, Pain, 03 medical and health sciences, ROS, reactive oxygen species, NMDAR, N-methyl-d-aspartate receptors, NLR Family, Pyrin Domain-Containing 3 Protein, PKC, protein kinase C, medicine, Animals, Humans, business.industry, Organic Chemistry, ASC, apoptosis-associated speck-like protein containing CARD, IBA-1, ionized calcium binding adapter molecule 1, medicine.disease, NLRP3 inflammasome, 030104 developmental biology, lcsh:Biology (General), BSA, bovine serum albumin, business, DAPI, 4′, 6-diamidino-2-phenylindole, 030217 neurology & neurosurgery
-
9
المؤلفون: Limei Piao, Ying Wan, Xian Wu Cheng, Chenglin Yu
المصدر: International Journal of Cardiology: Heart & Vasculature, Vol 28, Iss, Pp 100516-(2020)
International Journal of Cardiology. Heart & Vasculatureمصطلحات موضوعية: Cathepsin, medicine.medical_specialty, lcsh:Diseases of the circulatory (Cardiovascular) system, business.industry, NASH, non-alcoholic steatohepatitis, CTSs, cathepsins, NAFLD, Non-alcoholic fatty liver disease, FPC, fructose-palmitate-cholesterol, LDL - Low density lipoprotein, CTSB−/−, cathepsin B deficiency, Scad, short-chain acyl dehydrogenase-1, CTSB+/+, wild-type, LDL, low density lipoprotein, Editorial, Endocrinology, CSTB, cathepsin B, lcsh:RC666-701, FABP4, fatty acid binding protein 4, Internal medicine, medicine, MMP, metalloproteinase, Cardiology and Cardiovascular Medicine, business
-
10
المصدر: Virus Research
مصطلحات موضوعية: Rotavirus, 0301 basic medicine, Cancer Research, LP, late-penetrating, viruses, ReoT1L, mammalian reovirus type 1 Lang, medicine.disease_cause, Receptor, IGF Type 2, Virus entry, Mice, fluids and secretions, Vim, Vimentin, Protein Isoforms, RNA, Small Interfering, CI, cation-independent, Infectivity, LDH, lactate dehydrogenase, SORT1, Sortilin-1, CD, cation-dependent, virus diseases, CTSS, Cathepsin S, Infectious Diseases, Host-Pathogen Interactions, GM2AP, GM2 activator protein, LIMP2, lysosomal integral membrane protein 2, trans-Golgi Network, TGN, trans-golgi-network, Proteases, Genotype, Endosome, TLPs, triple-layered particles, CTSB, cathepsin B, Endosomes, CTSL1, Cathepsin L1, Biology, EP, early-penetrating, Article, Virus, Cathepsin, Cell Line, Microbiology, 03 medical and health sciences, Species Specificity, Viral entry, Virology, medicine, Animals, Humans, EEs, early endosomes, MEs, maturing endosomes, LEs, late endosomes, Biological Transport, Fibroblasts, Virus Internalization, Sortilin, Cathepsins, Macaca mulatta, Mannose-6-phosphate receptors, DLPs, double layered particles, Adaptor Proteins, Vesicular Transport, 030104 developmental biology, Gene Expression Regulation, Cytoplasm, Caco-2 Cells, M6PR, mannose-6-phosphate receptor(s)