المؤلفون: Rayner M. L. Queiroz, Siân C. Piper, Johanna S. Rees, Sam Strickson, Emmanuel Briend, Choon Pei Low, G. John Ferguson, Kathryn S. Lilley, Antony P. Jackson, Donna K. Finch

المساهمون: Rees, Johanna S [0000-0003-2066-8617], Apollo - University of Cambridge Repository

مصطلحات موضوعية: Proteomics, Threonine, Proteome, T-Lymphocytes, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Blood Donors, Lymphocyte Activation, Biochemistry, SPPLAT, Guanine Nucleotide Exchange Factors, Humans, Phosphorylation, Molecular Biology, Cells, Cultured, Interleukin-7, phosphoproteomics, Cell Biology, CYTIP/cytohesin, Lymphocyte Function-Associated Antigen-1, Recombinant Proteins, IL7, Actin Cytoskeleton, LFA, TCR, Signal Transduction, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bd18a14737c71474063278e134f316
https://www.repository.cam.ac.uk/handle/1810/332866

المؤلفون: Queiroz RML; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K.; Cambridge Centre for Proteomics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, U.K., Piper SC; Bioscience Asthma, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Cambridge, U.K., Rees JS; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K.; Cambridge Centre for Proteomics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, U.K., Strickson S; Bioscience Asthma, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Cambridge, U.K., Briend E; BioPharmaceutical R&D, AstraZeneca, Cambridge, U.K., Low CP; Biologic Therapeutics 3, Antibody Discovery & Protein Engineering, R&D, AstraZeneca, Cambridge, U.K., Ferguson GJ; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Cambridge, U.K., Lilley KS; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K.; Cambridge Centre for Proteomics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, U.K., Jackson AP; Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K., Finch DK; BioPharmaceutical R&D, AstraZeneca, Cambridge, U.K.

المصدر: The Biochemical journal [Biochem J] 2022 Feb 11; Vol. 479 (3), pp. 225-243.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

مواضيع طبية MeSH: Guanine Nucleotide Exchange Factors/*metabolism , Interleukin-7/*pharmacology , Lymphocyte Function-Associated Antigen-1/*metabolism , Proteome/*metabolism , Proteomics/*methods , Receptors, Antigen, T-Cell/*metabolism , Signal Transduction/*drug effects , T-Lymphocytes/*immunology , Transcription Factors/*metabolism, Actin Cytoskeleton/metabolism ; Blood Donors ; Cells, Cultured ; Humans ; Lymphocyte Activation/drug effects ; Phosphorylation/drug effects ; Recombinant Proteins/pharmacology ; Threonine/metabolism