المؤلفون: Calses PC; Departments of Discovery Oncology, Genentech Inc, South San Francisco, California, USA; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Pham VC; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Guarnaccia AD; Departments of Discovery Oncology, Genentech Inc, South San Francisco, California, USA; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Choi M; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Verschueren E; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Bakker ST; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA., Pham TH; Departments of Discovery Oncology, Genentech Inc, South San Francisco, California, USA., Hinkle T; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Liu C; Departments of Discovery Oncology, Genentech Inc, South San Francisco, California, USA., Chang MT; Department of Bioinformatics, Genentech Inc, South San Francisco, California, USA., Kljavin N; Department of Molecular Oncology, Genentech Inc, South San Francisco, California, USA., Bakalarski C; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA., Haley B; Departments of Discovery Oncology, Genentech Inc, South San Francisco, California, USA., Zou J; Department of Biology, Research Service Division, WuXi AppTec, Shanghai, China., Yan C; Department of Biology, Research Service Division, WuXi AppTec, Shanghai, China., Song X; Department of Biology, Research Service Division, WuXi AppTec, Shanghai, China., Lin X; Department of Biology, Research Service Division, WuXi AppTec, Shanghai, China., Rowntree R; Department of Molecular Oncology, Genentech Inc, South San Francisco, California, USA., Ashworth A; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA., Dey A; Departments of Discovery Oncology, Genentech Inc, South San Francisco, California, USA. Electronic address: anweshad@gene.com., Lill JR; Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, South San Francisco, California, USA. Electronic address: jlill@gene.com.

المصدر: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2023 Feb; Vol. 22 (2), pp. 100496. Date of Electronic Publication: 2023 Jan 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , DNA Repair*/physiology , TEA Domain Transcription Factors*/metabolism, Humans ; Carcinogenesis/metabolism ; DNA-Binding Proteins/metabolism ; Transcription Factors/metabolism

المؤلفون: Calses PC; Department of Discovery Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA; Department of Microchemistry, Proteomics, and Lipidomics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Crawford JJ; Department of Discovery Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Lill JR; Department of Microchemistry, Proteomics, and Lipidomics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Dey A; Department of Discovery Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: dey.anwesha@gene.com.

المصدر: Trends in cancer [Trends Cancer] 2019 May; Vol. 5 (5), pp. 297-307. Date of Electronic Publication: 2019 May 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101665956 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-8025 (Electronic) Linking ISSN: 24058025 NLM ISO Abbreviation: Trends Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*/drug effects, Neoplasms/*metabolism , Protein Serine-Threonine Kinases/*metabolism, Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Biomarkers ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Drug Discovery ; Gene Expression Regulation, Neoplastic ; Hippo Signaling Pathway ; Humans ; Neoplasms/etiology ; Neoplasms/pathology ; Neoplasms/therapy ; Protein Serine-Threonine Kinases/genetics

المؤلفون: Webster JD; Department of Pathology, Genentech, Inc., South San Francisco, California., Pham TH; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California., Wu X; Department of Translational Immunology, Genentech, Inc., South San Francisco, California., Hughes NW; Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Li Z; Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.; Department of Pathology, Peking University Cancer Hospital & Institute, Beijing, China., Totpal K; Department of Translational Oncology, Genentech, Inc., South San Francisco, California., Lee HJ; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California., Calses PC; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California., Chaurushiya MS; Department of Physiological Chemistry, Genentech, Inc., South San Francisco, California., Stawiski EW; Department of Molecular Biology, Genentech, Inc., South San Francisco, California., Modrusan Z; Department of Molecular Biology, Genentech, Inc., South San Francisco, California., Chang MT; Department of Bioinformatics, Genentech, Inc., South San Francisco, California., Tran C; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California., Lee WP; Department of Translational Immunology, Genentech, Inc., South San Francisco, California., Chalasani S; Department of Pathology, Genentech, Inc., South San Francisco, California., Hung J; Department of Pathology, Genentech, Inc., South San Francisco, California., Sharma N; Department of Pathology, Genentech, Inc., South San Francisco, California., Chan S; Department of Pathology, Genentech, Inc., South San Francisco, California., Hotzel K; Department of Pathology, Genentech, Inc., South San Francisco, California., Talevich E; Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Shain A; Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Xu M; Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Lill J; Department of Microchemistry, Proteomics and Lipidomics, Genentech, Inc., South San Francisco, California., Dixit VM; Department of Physiological Chemistry, Genentech, Inc., South San Francisco, California., Bastian BC; Departments of Dermatology and Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California., Dey A; Department of Discovery Oncology, Genentech, Inc., South San Francisco, California.

المصدر: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2019 Mar; Vol. 32 (2), pp. 269-279. Date of Electronic Publication: 2018 Sep 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Blackwell Munksgaard Country of Publication: England NLM ID: 101318927 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-148X (Electronic) Linking ISSN: 17551471 NLM ISO Abbreviation: Pigment Cell Melanoma Res

مواضيع طبية MeSH: Carcinogenesis/*genetics , Carcinogenesis/*pathology , Melanoma/*genetics , Melanoma/*pathology , Mutation/*genetics , Proto-Oncogene Proteins B-raf/*genetics , Skin Neoplasms/*genetics , Skin Neoplasms/*pathology , Tumor Suppressor Proteins/*metabolism , Ubiquitin Thiolesterase/*metabolism, Animals ; Cell Line, Tumor ; Cell Proliferation ; DNA Damage ; Epithelial-Mesenchymal Transition/genetics ; Gene Deletion ; Gene Expression Regulation, Neoplastic ; Histones/metabolism ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Melanocytes/metabolism ; Melanocytes/pathology ; Mice, Inbred C57BL ; Mice, Knockout ; Transcription, Genetic ; Ubiquitination ; Melanoma, Cutaneous Malignant

المؤلفون: Calses PC; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Molecular and Cellular Biology Graduate Program, University of Washington, 1959 NE Pacific, HSB T-466, Seattle, WA 98195-7275, USA., Dhillon KK; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA., Tucker N; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA., Chi Y; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA., Huang JW; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Molecular and Cellular Biology Graduate Program, University of Washington, 1959 NE Pacific, HSB T-466, Seattle, WA 98195-7275, USA., Kawasumi M; Division of Dermatology, Department of Medicine, University of Washington, 850 Republican St., Seattle, WA 98109-4714, USA., Nghiem P; Division of Dermatology, Department of Medicine, University of Washington, 850 Republican St., Seattle, WA 98109-4714, USA., Wang Y; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA., Clurman BE; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA., Jacquemont C; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA., Gafken PR; Proteomics Core Facility, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., DE-352, Seattle, WA 98109-1024, USA., Sugasawa K; Biosignal Research Center, Organization of Advanced Science and Technology, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan., Saijo M; Graduate School of Frontier Biosciences, Osaka University, Yamadaoka 1-3, Suita, Osaka 565-0871, Japan., Taniguchi T; Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., C1-015, Seattle, WA 98109-1024, USA; Department of Molecular Life Science, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. Electronic address: ttaniguc@fhcrc.org.

المصدر: Cell reports [Cell Rep] 2017 Apr 04; Vol. 19 (1), pp. 162-174.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage*, MicroRNAs/*metabolism , RNA-Binding Proteins/*metabolism , Ribonuclease III/*metabolism, Animals ; Anisomycin/metabolism ; Anthracenes/metabolism ; DNA/metabolism ; DNA/radiation effects ; DNA Repair ; HCT116 Cells ; HeLa Cells ; Humans ; MAP Kinase Kinase 4/antagonists & inhibitors ; MAP Kinase Kinase 4/metabolism ; Mice ; Phosphorylation ; RNA Polymerase II/metabolism ; RNA-Binding Proteins/genetics ; Ribonuclease III/genetics ; Ultraviolet Rays