المؤلفون: Campion, SN., Potter, DM., Bowman, CJ., Catlin, NR., Davis, S., Millard, C., Nowland, WS., Stethem, CM., Hollingshead, BD., Radi, ZA., Coder, PS., Cappon, GD.

المصدر: In Reproductive Toxicology October 2022 113:35-41

المؤلفون: Catlin NR; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA. Electronic address: natasha.catlin@pfizer.com., Cappon GD; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA; Current: ToxStrategies, Katy, TX, USA., Davenport SD; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Stethem CM; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Nowland WS; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Campion SN; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA., Bowman CJ; Drug Safety Research and Development, Pfizer Research & Development, Groton, CT, USA.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2024 Aug 09; Vol. 129, pp. 108686. Date of Electronic Publication: 2024 Aug 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

المؤلفون: Bowman CJ; Pfizer Research & Development, Groton, Connecticut, USA., Campion SN; Pfizer Research & Development, Groton, Connecticut, USA., Catlin NR; Pfizer Research & Development, Groton, Connecticut, USA., Nowland WS; Pfizer Research & Development, Groton, Connecticut, USA., Stethem CM; Pfizer Research & Development, Groton, Connecticut, USA., Radi ZA; Pfizer Research & Development, Cambridge, Massachusetts, USA., Cappon GD; Pfizer Research & Development, Groton, Connecticut, USA.

المصدر: Birth defects research [Birth Defects Res] 2024 May; Vol. 116 (5), pp. e2345.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101701004 Publication Model: Print Cited Medium: Internet ISSN: 2472-1727 (Electronic) NLM ISO Abbreviation: Birth Defects Res Subsets: MEDLINE

مواضيع طبية MeSH: Fertility*/drug effects , Janus Kinase 1*/antagonists & inhibitors , Janus Kinase 1*/metabolism , Pyrimidines*/pharmacology , Sulfonamides*/pharmacology, Female ; Animals ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Embryo Implantation/drug effects ; Janus Kinase Inhibitors/pharmacology ; Pregnancy Rate

المؤلفون: Garnsey MR; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Smith AC; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Polivkova J; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Arons AL; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Bai G; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Blakemore C; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Boehm M; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Buzon LM; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Campion SN; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Cerny M; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Chang SC; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Coffman K; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Farley KA; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Fonseca KR; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Ford KK; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Garren J; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Kong JX; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Koos MRM; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Kung DW; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Lian Y; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Li MM; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Li Q; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Martinez-Alsina LA; Pfizer, Incorporated, Groton, Connecticut 06340, United States., O'Connor R; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Ogilvie K; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Omoto K; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Raymer B; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Reese MR; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Ryder T; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Samp L; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Stevens KA; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Widlicka DW; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Yang Q; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Zhu K; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Fortin JP; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Sammons MF; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2023 Mar 09; Vol. 66 (5), pp. 3195-3211. Date of Electronic Publication: 2023 Feb 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Receptor, Melanocortin, Type 4* , Appetite*, Rats ; Humans ; Animals ; Cachexia/drug therapy ; Anorexia/drug therapy ; Molecular Conformation

المؤلفون: Campion SN; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA., Bowman CJ; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA., Fuchs A; Labcorp Early Development Services GmbH, Muenster, Germany., Karanian D; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA., Rana P; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA., Cappon GD; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA.

المصدر: Birth defects research [Birth Defects Res] 2023 Feb 01; Vol. 115 (3), pp. 348-356. Date of Electronic Publication: 2022 Nov 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101701004 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-1727 (Electronic) NLM ISO Abbreviation: Birth Defects Res Subsets: MEDLINE

مواضيع طبية MeSH: Receptor, Fibroblast Growth Factor, Type 3*/genetics , Receptor, Fibroblast Growth Factor, Type 3*/metabolism , Receptor, Fibroblast Growth Factor, Type 3*/pharmacology , Achondroplasia*/drug therapy , Achondroplasia*/genetics , Achondroplasia*/metabolism, Animals ; Humans ; Child ; Infant ; Macaca fascicularis/metabolism ; Bone Development ; Bone and Bones/metabolism

المؤلفون: Catlin NR; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Bowman CJ; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Campion SN; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Lewis EM; Charles River Laboratories, Inc., Safety Assessment, Horsham, Pennsylvania 19044, USA., Nowland WS; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Stethem C; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA., Cappon GD; Drug Safety Research, Development, & Medical, Pfizer Worldwide Research & Development, Groton, Connecticut 06340, USA.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2022 Sep 24; Vol. 189 (2), pp. 225-236.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Diacylglycerol O-Acyltransferase*/metabolism , Diacylglycerol O-Acyltransferase*/pharmacology , Reproduction*, Animals ; Female ; Fertility ; Pregnancy ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Triglycerides

المؤلفون: Catlin NR; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA. Electronic address: natasha.catlin@pfizer.com., Bowman CJ; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Campion SN; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Cheung JR; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Nowland WS; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Sathish JG; Pfizer Worldwide Research, Development & Medical, Pearl River, NY, 10965, USA., Stethem CM; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA., Updyke L; Pfizer Worldwide Research, Development & Medical, Cambridge, MA, 02139, USA., Cappon GD; Pfizer Worldwide Research, Development & Medical, Groton, CT, 06340, USA.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2022 Mar; Vol. 108, pp. 56-61. Date of Electronic Publication: 2022 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Drug Treatment*, Antiviral Agents/*toxicity , Embryonic Development/*drug effects , Fertility/*drug effects , Lactams/*toxicity , Leucine/*toxicity , Nitriles/*toxicity , Proline/*toxicity , Ritonavir/*toxicity, Animals ; Drug Combinations ; Female ; Infertility/chemically induced ; Male ; Pregnancy ; Rabbits ; Rats ; Rats, Wistar

المؤلفون: Bowman CJ; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA. Electronic address: christopher.j.bowman@pfizer.com., Bouressam M; Charles River Laboratories France Safety Assessmsent SAS, Lyon, France., Campion SN; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA., Cappon GD; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA., Catlin NR; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Groton, CT, USA., Cutler MW; Vaccine Research and Development, Pfizer Worldwide Research, Development & Medical, Pearl River, NY, USA., Diekmann J; Non-Clinical Safety, BioNTech SE, Mainz, Germany., Rohde CM; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Pearl River, NY, USA., Sellers RS; Drug Safety Research and Development, Pfizer Worldwide Research, Development & Medical, Pearl River, NY, USA., Lindemann C; Non-Clinical Safety, BioNTech SE, Mainz, Germany.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2021 Aug; Vol. 103, pp. 28-35. Date of Electronic Publication: 2021 May 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Fertility* , Fetal Development*, COVID-19 Vaccines/*toxicity, Animals ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; BNT162 Vaccine ; COVID-19 Vaccines/pharmacology ; Cesarean Section ; Female ; Lactation ; Pregnancy ; Rats ; Rats, Wistar

المؤلفون: Catlin NR; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Bowman CJ; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Campion SN; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Davenport SD; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Esler WP; Internal Medicine Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA., Kumpf SW; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Lewis EM; Charles River Laboratories, Inc, Safety Assessment, Horsham, PA., Nowland WS; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Ross TT; Internal Medicine Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA., Stedman DS; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Stethem C; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT., Cappon GD; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2021 Jan 28; Vol. 179 (2), pp. 183-194.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Acetyl-CoA Carboxylase*/genetics , Acetyl-CoA Carboxylase*/metabolism , Diabetes Mellitus, Type 2*, Animals ; Lipogenesis ; Mice ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Zebrafish/metabolism

المؤلفون: Catlin NR; Pfizer, Inc., Groton, CT, USA. Electronic address: natasha.catlin@pfizer.com., Stethem C; Pfizer, Inc., Groton, CT, USA., Bowman CJ; Pfizer, Inc., Groton, CT, USA., Campion SN; Pfizer, Inc., Groton, CT, USA., Nowland WS; Pfizer, Inc., Groton, CT, USA., Cappon GD; Pfizer, Inc., Groton, CT, USA.

المصدر: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2021 Jan; Vol. 99, pp. 138-143. Date of Electronic Publication: 2020 Oct 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Abnormalities, Drug-Induced* , Models, Animal*, Drug Evaluation, Preclinical/*methods , Teratogens/*toxicity, Animals ; Embryo, Mammalian/drug effects ; Fetal Death/etiology ; Mice, Knockout ; Mice