-
1دورية أكاديمية
المؤلفون: Fehm T; University Hospital Düsseldorf, Center for Integrated Oncology ABCD, Düsseldorf, Germany. Electronic address: tanja.fehm@med.uni-duesseldorf.de., Cottone F; Daiichi Sankyo, Rome, Italy., Dunton K; Daiichi Sankyo, Uxbridge, UK., André F; Institut Gustave Roussy, Université Paris Saclay, Villejuif, France., Krop I; Yale Cancer Center, New Haven, CT, USA., Park YH; Samsung Medical Center, Seoul, South Korea., De Laurentiis M; Istituto Nazionale Tumori IRCCS Fondazione G Pascale, Naples, Italy., Miyoshi Y; Hyogo College of Medicine University Hospital, Hyogo, Japan., Armstrong A; The Christie Hospital, Manchester, UK., Borrego MR; Hospital Universitario Virgen del Rocio, Seville, Spain., Yerushalmi R; Rabin Medical Center-Beilinson Campus, Tel Aviv University, Tel Aviv, Israel., Duhoux FP; Cliniques universitaires Saint-Luc, Brussels, Belgium., Takano T; The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan., Lu W; Daiichi Sankyo, Basking Ridge, NJ, USA., Egorov A; Daiichi Sankyo, Basking Ridge, NJ, USA., Kim SB; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
المصدر: The Lancet. Oncology [Lancet Oncol] 2024 May; Vol. 25 (5), pp. 614-625.
نوع المنشور: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Multicenter Study; Comparative Study
بيانات الدورية: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/*analogs & derivatives, Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Trastuzumab*/therapeutic use , Trastuzumab*/administration & dosage , Patient Reported Outcome Measures* , Receptor, ErbB-2*/metabolism , Camptothecin*/therapeutic use , Camptothecin*/administration & dosage , Immunoconjugates*, Humans ; Female ; Middle Aged ; Aged ; Adult ; Capecitabine/therapeutic use ; Capecitabine/administration & dosage ; Quality of Life ; Progression-Free Survival ; Lapatinib/therapeutic use ; Lapatinib/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
-
2دورية أكاديمية
مؤلفون مشاركون: Trastuzumab Deruxtecan Clinical Management Pathway and Adverse Reaction Management Consensus Expert Group
المصدر: Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2024 Apr 23; Vol. 46 (4), pp. 304-318.
نوع المنشور: English Abstract; Journal Article
بيانات الدورية: Publisher: Chinese Medical Association Country of Publication: China NLM ID: 7910681 Publication Model: Print Cited Medium: Print ISSN: 0253-3766 (Print) Linking ISSN: 02533766 NLM ISO Abbreviation: Zhonghua Zhong Liu Za Zhi Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/*analogs & derivatives, Trastuzumab*/adverse effects , Trastuzumab*/therapeutic use , Immunoconjugates*/adverse effects , Immunoconjugates*/therapeutic use , Breast Neoplasms*/drug therapy , Breast Neoplasms*/metabolism , Receptor, ErbB-2*/metabolism , Camptothecin*/adverse effects , Camptothecin*/therapeutic use, Humans ; Female ; China ; Antineoplastic Agents, Immunological/adverse effects ; Antineoplastic Agents, Immunological/therapeutic use ; Consensus ; East Asian People
-
3دورية أكاديمية
المؤلفون: Hattori M; Department of Breast Oncology, Aichi Cancer Center, Nagoya, Japan., Honma N; Department of Pathology, Toho University Faculty of Medicine, Tokyo, Japan., Nagai S; Division of Breast Oncology, Saitama Cancer Center, Saitama, Japan., Narui K; Department of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan., Shigechi T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyusyu University, Fukuoka, Japan., Ozaki Y; Department of Breast Medical Oncology, Advanced Medical Development, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan., Yoshida M; Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan., Sakatani T; Department of Diagnostic Pathology, Nippon Medical School Hospital, Tokyo, Japan., Sasaki E; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan., Tanabe Y; Department of Medical Oncology, Toranomonn Hospital, Tokyo, Japan., Tsurutani J; Advanced Cancer Translational Research Institute, Showa University, Tokyo, Japan., Takano T; Breast Medical Oncology Department, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan., Saji S; Department of Medical Oncology, School of Medicine, Fukushima Medical University, Fukushima, Japan., Masuda S; Division of Oncologic Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan., Horii R; Department of Diagnostic Pathology, Yokohama City University Medical Center, Yokohama, Japan., Tsuda H; Department of Basic Pathology, National Defense Medical College, Saitama, Japan., Yamaguchi R; Department of Diagnostic Pathology, Nagasaki University Hospital, Nagasaki, Japan., Toyama T; Department of Breast Surgery, Nagoya City University, Nagoya, Japan., Yamauchi C; Department of Radiation Oncology, Shiga General Hospital, Moriyama, Japan., Toi M; Tokyo Metropolitan Komagome Hospital, Tokyo, Japan., Yamamoto Y; Department of Breast and Endocrine Surgery, Kumamoto University Hospital, Kumamoto, Japan. yyamamoto@kumamoto-u.ac.jp.
المصدر: Breast cancer (Tokyo, Japan) [Breast Cancer] 2024 May; Vol. 31 (3), pp. 335-339. Date of Electronic Publication: 2024 Mar 04.
نوع المنشور: Journal Article; Practice Guideline
بيانات الدورية: Publisher: Maruzen Co Country of Publication: Japan NLM ID: 100888201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-4233 (Electronic) Linking ISSN: 13406868 NLM ISO Abbreviation: Breast Cancer Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/*analogs & derivatives, Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Trastuzumab*/therapeutic use , Receptor, ErbB-2*/metabolism , Camptothecin*/therapeutic use, Humans ; Female ; Japan ; Immunoconjugates/therapeutic use ; Antineoplastic Agents, Immunological/therapeutic use ; East Asian People
-
4دورية أكاديمية
المؤلفون: Farhoudi L; Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran., Maryam Hosseinikhah S; Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran., Vahdat-Lasemi F; Department of Medical Biotechnology and Nanotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Sukhorukov VN; Institute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, Moscow 125315, Russia., Kesharwani P; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India. Electronic address: prashantdops@gmail.com., Sahebkar A; Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: amir_saheb2000@yahoo.com.
المصدر: International journal of pharmaceutics [Int J Pharm] 2024 Jun 25; Vol. 659, pp. 124292. Date of Electronic Publication: 2024 May 30.
نوع المنشور: Journal Article; Review
بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
مواضيع طبية MeSH: Micelles* , Camptothecin*/administration & dosage , Camptothecin*/chemistry , Camptothecin*/analogs & derivatives , Camptothecin*/pharmacokinetics , Camptothecin*/pharmacology , Polymers*/chemistry , Antineoplastic Agents, Phytogenic*/administration & dosage , Antineoplastic Agents, Phytogenic*/chemistry , Antineoplastic Agents, Phytogenic*/pharmacokinetics , Drug Delivery Systems*/methods, Humans ; Animals ; Neoplasms/drug therapy ; Drug Carriers/chemistry ; Solubility ; Tissue Distribution ; Hydrophobic and Hydrophilic Interactions
-
5دورية أكاديمية
المؤلفون: Xie L; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Zhang Q; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Zhu Q; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Wang Y; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Niu S; Shandong Institute for Food and Drug Control, Ji'nan 250101, China., Zhang X; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Huang Y; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Li J; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Liu X; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Xue Z; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China., Zhao X; Department of Pharmacy, The First Affiliated Hospital of Chengdu Medical College, Clinical Medical College, Chengdu Medical College, Chengdu 610083, China., Zheng Y; School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610083, China.
المصدر: Molecular pharmaceutics [Mol Pharm] 2024 May 06; Vol. 21 (5), pp. 2327-2339. Date of Electronic Publication: 2024 Apr 05.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/chemistry , Camptothecin*/administration & dosage , Camptothecin*/pharmacokinetics , Camptothecin*/pharmacology , Liposomes*/chemistry , Lipids*/chemistry, Animals ; Mice ; Humans ; Drug Liberation ; Drug Delivery Systems/methods ; Polyethylene Glycols/chemistry ; Cell Line, Tumor ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/pharmacokinetics ; Antineoplastic Agents, Phytogenic/pharmacology ; Female ; Click Chemistry/methods ; Mice, Inbred BALB C
-
6دورية أكاديمية
المؤلفون: Doan TN; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam., Le TD; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam., Ho NA; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam., Ho TT; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam.; Graduate University of Science and Technology, Hanoi, Vietnam., Do TT; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam., Hoang H; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam., Nguyen MH; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam.; Graduate University of Science and Technology, Hanoi, Vietnam., Bui TM; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam., Chu HH; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), Hanoi, Viet Nam.; Graduate University of Science and Technology, Hanoi, Vietnam.
المصدر: Science progress [Sci Prog] 2024 Apr-Jun; Vol. 107 (2), pp. 368504241253675.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: SAGE Publications Country of Publication: England NLM ID: 0411361 Publication Model: Print Cited Medium: Internet ISSN: 2047-7163 (Electronic) Linking ISSN: 00368504 NLM ISO Abbreviation: Sci Prog Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/pharmacology , Camptothecin*/chemistry , Camptothecin*/biosynthesis , Endophytes*/metabolism , Endophytes*/isolation & purification , Endophytes*/chemistry , Fungi*/isolation & purification , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/isolation & purification, Humans ; A549 Cells ; Cell Line, Tumor
-
7دورية أكاديمية
المؤلفون: Venturi S; Department Chemistry, Materials and Chemical Engineering 'G. Natta', Politecnico of Milan, Piazza Leonardo da Vinci 32, 20133 Milano, Italy. francesco.gatti@polimi.it., Chiaradonna F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy., Gatti FG; Department Chemistry, Materials and Chemical Engineering 'G. Natta', Politecnico of Milan, Piazza Leonardo da Vinci 32, 20133 Milano, Italy. francesco.gatti@polimi.it., La Ferla B; Department of Earth and Environmental Science, University of Milano-Bicocca, Piazza della Scienza 1, 20126 Milano, Italy. barbara.laferla@unimib.it., Palorini R; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy., Zerbato B; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.
المصدر: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Jun 20; Vol. 60 (51), pp. 6524-6527. Date of Electronic Publication: 2024 Jun 20.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/chemistry , Camptothecin*/pharmacology , Prodrugs*/chemistry , Prodrugs*/pharmacology , Prodrugs*/chemical synthesis, Humans ; Cell Line, Tumor ; Drug Liberation ; Pancreatic Neoplasms/drug therapy ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Delayed-Action Preparations/chemistry ; Molecular Structure
-
8دورية أكاديمية
المؤلفون: Banadka A; Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560 029, Karnataka, India., Narasimha SW; Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560 029, Karnataka, India., Dandin VS; Department of Biology, JSS College, Dharwad, India., Naik PM; Department of Botany, Karnatak University, Dharwad, 580003, Karnataka, India., Vennapusa AR; Department of Agriculture and Natural Resources, Delaware State University, Dover, DE, 19901, USA. avennapusa@desu.edu., Melmaiee K; Department of Agriculture and Natural Resources, Delaware State University, Dover, DE, 19901, USA., Vemanna RS; Laboratory of Plant Functional Genomics, Regional Center for Biotechnology, Faridabad, 121001, Haryana, India., Al-Khayri JM; Department of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al- Ahsa, 31982, Saudi Arabia. jkhayri@kfu.edu.sa., Thiruvengadam M; Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, South Korea., Nagella P; Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560 029, Karnataka, India. praveen.n@christuniversity.in.
المصدر: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2024 Jun 19; Vol. 108 (1), pp. 382. Date of Electronic Publication: 2024 Jun 19.
نوع المنشور: Journal Article; Review
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0614 (Electronic) Linking ISSN: 01757598 NLM ISO Abbreviation: Appl Microbiol Biotechnol Subsets: MEDLINE
مواضيع طبية MeSH: Camptothecin*/biosynthesis , Biotechnology*/methods , Endophytes*/metabolism , Endophytes*/genetics , Camptotheca*/metabolism, Antineoplastic Agents, Phytogenic/biosynthesis ; Humans
-
9دورية أكاديمية
المؤلفون: Weiten R; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany.; Department of Urology Uro-Oncology, Robot-Assisted and Specialized Urologic Surgery, University Hospital Cologne, Köln, Germany., Niemann M; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany., Below E; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany.; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany., Friker LL; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany.; Institute of Neuropathology, University Hospital Bonn, Bonn, Germany., Ralser DJ; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany.; Department of Gynaecology and Gynaecological Oncology, University Hospital Bonn, Bonn, Germany., Toma M; Institute of Pathology, University Hospital Bonn, Bonn, Germany., Kristiansen G; Institute of Pathology, University Hospital Bonn, Bonn, Germany., Hahn O; Department of Urology, University Hospital Göttingen, Göttingen, Germany., Zechel S; Institute of Neuropathology, University Hospital Göttingen, Göttingen, Germany., Grünwald V; Clinic for Internal Medicine (Tumor Research) and Clinic for Urology, Interdisciplinary Genitourinary Oncology at the West-German Cancer Center, University Hospital Essen, Essen, Germany., Bald T; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany., Siewert J; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany., Pietsch T; Institute of Neuropathology, University Hospital Bonn, Bonn, Germany., Ritter M; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany., Hölzel M; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany., Eckstein M; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Alajati A; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany., Krausewitz P; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany., Klümper N; Department of Urology and Paediatric Urology, University Hospital Bonn, Bonn, Germany.; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany.
المصدر: Cancer medicine [Cancer Med] 2024 Jun; Vol. 13 (12), pp. e7320.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE
مواضيع طبية MeSH: Prostatic Neoplasms, Castration-Resistant*/drug therapy , Prostatic Neoplasms, Castration-Resistant*/pathology , Immunoconjugates*/therapeutic use , Immunoconjugates*/pharmacology , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/genetics , Antigens, Neoplasm*/immunology , Brain Neoplasms*/secondary , Brain Neoplasms*/drug therapy , Antibodies, Monoclonal, Humanized*/therapeutic use , Antibodies, Monoclonal, Humanized*/pharmacology , Camptothecin*/analogs & derivatives , Camptothecin*/therapeutic use , Camptothecin*/pharmacology, Male ; Humans ; Cell Line, Tumor ; Nectins
-
10دورية أكاديمية
عنوان ترانسليتريتد: Risposta mantenuta al trattamento di seconda linea con sacituzumab govitecan in paziente con malattia encefalica e sistemica da TNBC.
المؤلفون: Di Lauro V; SC Oncologia clinica sperimentale di senologia, Dipartimento Corp-S assistenziale e di ricerca dei percorsi oncologici del Distretto toracico, INT Irccs Fondazione 'Giovanni Pascale', Napoli.
المصدر: Recenti progressi in medicina [Recenti Prog Med] 2024 Jun; Vol. 115 (6), pp. 31e-35e.
نوع المنشور: Case Reports; Journal Article; English Abstract
بيانات الدورية: Publisher: Il Pensiero Scientifico Editore Country of Publication: Italy NLM ID: 0401271 Publication Model: Print Cited Medium: Internet ISSN: 2038-1840 (Electronic) Linking ISSN: 00341193 NLM ISO Abbreviation: Recenti Prog Med Subsets: MEDLINE
مواضيع طبية MeSH: Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Antibodies, Monoclonal, Humanized*/administration & dosage , Antibodies, Monoclonal, Humanized*/therapeutic use , Antibodies, Monoclonal, Humanized*/pharmacology , Brain Neoplasms*/secondary , Brain Neoplasms*/drug therapy , Camptothecin*/analogs & derivatives , Camptothecin*/administration & dosage, Humans ; Middle Aged ; Female ; Immunoconjugates/administration & dosage ; Immunoconjugates/pharmacology ; Time Factors ; Disease Progression ; Liver Neoplasms/secondary ; Liver Neoplasms/drug therapy ; Treatment Outcome