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المؤلفون: Varty GB; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland., Canal CE; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland.; College of Pharmacy, Department of Pharmaceutical Sciences, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States., Mueller TA; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland.; BioIVT, Hicksville, New York 11803, United States., Hartsel JA; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland.; Consultant, UPS PO Box #105-650, 25422 Trabuco Road, Lake Forest, California 92630, United States., Tyagi R; College of Pharmacy, Department of Pharmaceutical Sciences, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States., Avery K; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland., Morgan ME; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland., Reichelt AC; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland.; Faculty of Biomedicine, University of Adelaide, Adelaide, South Australia 5005, Australia., Pathare P; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland., Stang E; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland., Palfreyman MG; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland., Nivorozhkin A; Cybin IRL Limited, North Wall Quay, 1 Spencer Dock, Dublin 1 DO1 X9R7, Ireland.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Apr 25; Vol. 67 (8), pp. 6144-6188. Date of Electronic Publication: 2024 Apr 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Phenethylamines*/pharmacology , Phenethylamines*/chemistry , Phenethylamines*/chemical synthesis , Serotonin 5-HT2 Receptor Agonists*/pharmacology , Serotonin 5-HT2 Receptor Agonists*/chemistry , Serotonin 5-HT2 Receptor Agonists*/chemical synthesis, Structure-Activity Relationship ; Animals ; Humans ; Administration, Oral ; Male ; Biological Availability ; Rats ; Mice ; Rats, Sprague-Dawley ; Drug Discovery ; Receptors, Serotonin, 5-HT2/metabolism ; Receptor, Serotonin, 5-HT2A/metabolism

المؤلفون: Saraf TS; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA., Chen Y; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA., Tyagi R; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA., Canal CE; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA. Electronic address: canal_ce@mercer.edu.

المصدر: Neuropharmacology [Neuropharmacology] 2024 Mar 01; Vol. 245, pp. 109774. Date of Electronic Publication: 2023 Nov 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

مواضيع طبية MeSH: Epilepsy, Reflex* , Fragile X Syndrome*/drug therapy , Fragile X Syndrome*/genetics , Fragile X Syndrome*/metabolism , Inferior Colliculi*/metabolism, Animals ; Female ; Male ; Mice ; Fragile X Mental Retardation Protein/genetics ; Fragile X Mental Retardation Protein/metabolism ; Mice, Knockout ; Receptor, Serotonin, 5-HT1A/genetics ; Receptor, Serotonin, 5-HT1A/metabolism ; Serotonin

المؤلفون: Tyagi R; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States., Saraf TS; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States., Canal CE; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States.

المصدر: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2023 Sep 18; Vol. 6 (10), pp. 1480-1491. Date of Electronic Publication: 2023 Sep 18 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

المؤلفون: Saraf TS; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States., McGlynn RP; Center for Drug Discovery, Department of Pharmaceutical Sciences, and Department of Chemistry and Chemical Biology, Northeastern University, 300 Huntington Street, Boston, Massachusetts 02115, United States., Bhatavdekar OM; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, 3400 North Charles Street, Croft Hall B27, Baltimore, Maryland 21218, United States., Booth RG; Center for Drug Discovery, Department of Pharmaceutical Sciences, and Department of Chemistry and Chemical Biology, Northeastern University, 300 Huntington Street, Boston, Massachusetts 02115, United States., Canal CE; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, 3001 Mercer University Drive, Atlanta, Georgia 30341, United States.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Dec 21; Vol. 13 (24), pp. 3629-3640. Date of Electronic Publication: 2022 Dec 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Auditory Cortex*/metabolism , Fragile X Syndrome*/drug therapy , Serotonin 5-HT1 Receptor Agonists*/pharmacology, Adult ; Animals ; Female ; Humans ; Male ; Mice ; Disease Models, Animal ; Electroencephalography ; Fragile X Mental Retardation Protein/genetics ; Fragile X Mental Retardation Protein/metabolism ; Mice, Knockout ; Receptor, Serotonin, 5-HT1D ; Serotonin

المؤلفون: Casey AB; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: abcasey@stanford.edu., Cui M; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA; Center for Drug Discovery, Northeastern University, Boston, MA 02115, USA., Booth RG; Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA; Center for Drug Discovery, Northeastern University, Boston, MA 02115, USA., Canal CE; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University Health Sciences Center, Mercer University, 3001 Mercer University Drive, Atlanta, GA 30341, USA.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2022 Jun; Vol. 200, pp. 115028. Date of Electronic Publication: 2022 Apr 04.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Depressive Disorder, Major* , Hallucinogens*/pharmacology, Humans ; Receptor, Serotonin, 5-HT2A ; Serotonin ; Serotonin 5-HT2 Receptor Agonists/pharmacology ; Serotonin 5-HT2 Receptor Agonists/therapeutic use

المؤلفون: Armstrong JL; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA 30341, USA., Saraf TS; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA 30341, USA., Bhatavdekar O; Johns Hopkins University, Department of Chemical and Biomolecular Engineering, 3400 North Charles Street, Croft Hall B27, Baltimore, MD 21218, USA., Canal CE; Mercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA 30341, USA. Electronic address: canal_ce@mercer.edu.

المصدر: Epilepsy research [Epilepsy Res] 2022 May; Vol. 182, pp. 106891. Date of Electronic Publication: 2022 Mar 08.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8703089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6844 (Electronic) Linking ISSN: 09201211 NLM ISO Abbreviation: Epilepsy Res Subsets: MEDLINE

مواضيع طبية MeSH: Fragile X Mental Retardation Protein*/genetics , Fragile X Syndrome*/genetics, Animals ; Disease Models, Animal ; Male ; Mice ; Mice, Knockout ; Seizures/genetics

المؤلفون: Canal CE; College of Pharmacy, Department of Pharmaceutical Sciences, Mercer University, Atlanta, Georgia 30341, United States., Leopoldo M; Dipartimento di Farmacia, Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Via Orabona 4, 70125 Bari, Italy.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Jan 19; Vol. 13 (2), pp. 185-186. Date of Electronic Publication: 2022 Jan 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, G-Protein-Coupled*, Ligands