المؤلفون: Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA lzhu2@houstonmethodist.org.; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Yerramilli P; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA., Pruitt L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA.

المصدر: Journal of bacteriology [J Bacteriol] 2020 Nov 04; Vol. 202 (23). Date of Electronic Publication: 2020 Nov 04 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 2985120R Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5530 (Electronic) Linking ISSN: 00219193 NLM ISO Abbreviation: J Bacteriol Subsets: MEDLINE

مواضيع طبية MeSH: Streptococcal Infections/*microbiology , Streptococcus agalactiae/*genetics, Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Base Sequence ; Gene Expression Regulation, Bacterial ; Hemolysis ; Histidine Kinase/genetics ; Histidine Kinase/metabolism ; Humans ; Phenotype ; Point Mutation ; Promoter Regions, Genetic ; Streptococcal Infections/blood ; Streptococcus agalactiae/metabolism ; Virulence Factors/genetics ; Virulence Factors/metabolism

المؤلفون: Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA lzhu2@houstonmethodist.org., Yerramilli P; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Pruitt L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Ojeda Saavedra M; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Waller AS; Animal Health Trust, Newmarket, Suffolk, United Kingdom., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA.

المصدر: Infection and immunity [Infect Immun] 2020 Sep 18; Vol. 88 (10). Date of Electronic Publication: 2020 Sep 18 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5522 (Electronic) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Bacterial*, Bacteremia/*microbiology , Streptococcal Infections/*microbiology , Streptococcus agalactiae/*genetics, Bacterial Proteins/genetics ; Genetic Fitness ; Genome, Bacterial/genetics ; Humans ; Microbial Viability/genetics ; Mutagenesis, Insertional ; Mutation ; Streptococcus agalactiae/growth & development ; Streptococcus agalactiae/pathogenicity ; Virulence/genetics

المؤلفون: Salazar E; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York., Perez KK; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pharmacy, Houston Methodist Hospital, Houston, Texas., Ashraf M; Division of Infectious Diseases, Department of Clinical Medicine, Houston Methodist Hospital, Houston, Texas., Chen J; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Castillo B; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Christensen PA; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Eubank T; Department of Pharmacy, Houston Methodist Hospital, Houston, Texas., Bernard DW; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York., Eagar TN; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York., Long SW; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas., Subedi S; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Olsen RJ; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas., Leveque C; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Schwartz MR; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Dey M; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Chavez-East C; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Rogers J; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Shehabeldin A; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Joseph D; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Williams G; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Thomas K; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Masud F; Division of Infectious Diseases, Department of Clinical Medicine, Houston Methodist Hospital, Houston, Texas; Department of Anesthesiology and Critical Care, Houston Methodist Hospital, Houston, Texas., Talley C; Academic Office of Clinical Trials, Houston Methodist Research Institute, Houston, Texas., Dlouhy KG; Academic Office of Clinical Trials, Houston Methodist Research Institute, Houston, Texas., Lopez BV; Academic Office of Clinical Trials, Houston Methodist Research Institute, Houston, Texas., Hampton C; Academic Office of Clinical Trials, Houston Methodist Research Institute, Houston, Texas., Lavinder J; Department of Molecular Biosciences, Dell Medical School, University of Texas at Austin, Austin, Texas., Gollihar JD; Combat Capabilities Development Command (CCDC) Army Research Laboratory-South, University of Texas at Austin, Austin, Texas., Maranhao AC; Department of Molecular Biosciences, Dell Medical School, University of Texas at Austin, Austin, Texas., Ippolito GC; Department of Molecular Biosciences, Dell Medical School, University of Texas at Austin, Austin, Texas; Department of Oncology, Dell Medical School, University of Texas at Austin, Austin, Texas., Saavedra MO; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas., Cantu CC; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas., Yerramilli P; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas., Pruitt L; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas., Musser JM; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York; Center for Molecular and Translational Human Infectious Diseases, Houston Methodist Research Institute, Houston, Texas. Electronic address: jmmusser@houstonmethodist.org.

المصدر: The American journal of pathology [Am J Pathol] 2020 Aug; Vol. 190 (8), pp. 1680-1690. Date of Electronic Publication: 2020 May 27.

نوع المنشور: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-2191 (Electronic) Linking ISSN: 00029440 NLM ISO Abbreviation: Am J Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Coronavirus Infections/*therapy , Pneumonia, Viral/*therapy, Adult ; Aged ; Betacoronavirus/genetics ; COVID-19 ; Female ; Humans ; Immunization, Passive ; Investigational New Drug Application ; Male ; Middle Aged ; Pandemics ; SARS-CoV-2 ; Texas ; Whole Genome Sequencing ; Young Adult ; COVID-19 Serotherapy

المؤلفون: Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Saavedra MO; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Kubiak SL; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Jenkins L; Department of Comparative Medicine, Houston Methodist Research Institute, Houston, Texas, USA., Waller AS; Animal Health Trust, Lanwades Park, Newmarket, United Kingdom., Sun Z; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA., Palzkill T; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA., Porter AR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA., DeLeo FR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA.

المصدر: JCI insight [JCI Insight] 2020 Jun 04; Vol. 5 (11). Date of Electronic Publication: 2020 Jun 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Bacterial* , Pharyngitis*/genetics , Pharyngitis*/metabolism , Pharyngitis*/microbiology , Pharyngitis*/pathology , Streptococcal Infections*/genetics , Streptococcal Infections*/metabolism , Streptococcal Infections*/pathology , Streptococcus pyogenes*/genetics , Streptococcus pyogenes*/metabolism , Streptococcus pyogenes*/pathogenicity , Virulence Factors*/genetics , Virulence Factors*/metabolism, Animals ; Disease Models, Animal ; Genome-Wide Association Study ; Humans ; Macaca fascicularis

المؤلفون: Salazar E, Perez KK, Ashraf M, Chen J, Castillo B, Christensen PA, Eubank T, Bernard DW, Eagar TN, Long SW, Subedi S, Olsen RJ, Leveque C, Schwartz MR, Dey M, Chavez-East C, Rogers J, Shehabeldin A, Joseph D, Williams G, Thomas K, Masud F, Talley C, Dlouhy KG, Lopez BV, Hampton C, Lavinder J, Gollihar JD, Maranhao AC, Ippolito GC, Saavedra MO, Cantu CC, Yerramilli P, Pruitt L, Musser JM

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2020 May 13. Date of Electronic Publication: 2020 May 13.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Ojeda Saavedra M; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Kubiak SL; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Jenkins L; Department of Comparative Medicine, Houston Methodist Research Institute, Houston, Texas., Yerramilli P; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Pruitt L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas., Charbonneau ARL; Department of Bacteriology Research, Animal Health Trust, Lanwades Park, Newmarket, United Kingdom; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom., Waller AS; Department of Bacteriology Research, Animal Health Trust, Lanwades Park, Newmarket, United Kingdom., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York. Electronic address: jmmusser@houstonmethodist.org.

المصدر: The American journal of pathology [Am J Pathol] 2020 Apr; Vol. 190 (4), pp. 862-873. Date of Electronic Publication: 2020 Mar 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-2191 (Electronic) Linking ISSN: 00029440 NLM ISO Abbreviation: Am J Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*metabolism , Membrane Proteins/*metabolism , Streptococcal Infections/*microbiology , Streptococcus pyogenes/*genetics , Streptococcus pyogenes/*pathogenicity , Vaginal Diseases/*microbiology, Animals ; Bacterial Proteins/genetics ; Disease Models, Animal ; Female ; Gene Expression Regulation, Bacterial ; Macaca fascicularis ; Membrane Proteins/genetics ; Streptococcal Infections/metabolism ; Streptococcus pyogenes/metabolism ; Vaginal Diseases/pathology ; Virulence

المؤلفون: Eraso JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Kachroo P; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America.; Departments of Pathology and Laboratory Medicine and Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Badu T; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Shannon S; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Saavedra MO; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Kubiak SL; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America., Porter AR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America., DeLeo FR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, United States of America.; Departments of Pathology and Laboratory Medicine and Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America.

المصدر: PloS one [PLoS One] 2020 Mar 26; Vol. 15 (3), pp. e0229064. Date of Electronic Publication: 2020 Mar 26 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*genetics , Fasciitis, Necrotizing/*microbiology , Streptococcal Infections/*microbiology , Streptococcus pyogenes/*genetics , Streptococcus pyogenes/*isolation & purification , Virulence/*genetics, Animals ; Disease Models, Animal ; Fasciitis, Necrotizing/pathology ; Gene Expression Regulation, Bacterial ; Genetic Heterogeneity ; Humans ; Mice ; Polymorphism, Genetic ; Streptococcal Infections/pathology ; Transcriptome ; Virulence Factors/genetics

المؤلفون: Kachroo P; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Eraso JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, USA.; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, USA., Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Kubiak SL; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Pruitt L; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Yerramilli P; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Ojeda Saavedra M; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Pensar J; Department of Mathematics and Statistics, Helsinki Institute of Information Technology, University of Helsinki, Helsinki, Finland., Corander J; Department of Mathematics and Statistics, Helsinki Institute of Information Technology, University of Helsinki, Helsinki, Finland.; Department of Biostatistics, University of Oslo, Oslo, Norway., Jenkins L; Comparative Medicine Program, Houston Methodist Research Institute, Houston, Texas, USA., Kao L; Department of Surgery, University of Texas McGovern Medical School, Houston, Texas, USA., Granillo A; Department of Internal Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA., Porter AR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA., DeLeo FR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, Texas, USA jmmusser@houstonmethodist.org.; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, USA.; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, USA.

المصدر: MBio [mBio] 2020 Feb 18; Vol. 11 (1). Date of Electronic Publication: 2020 Feb 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*, Fasciitis, Necrotizing/*microbiology , Myositis/*microbiology , Streptococcal Infections/*microbiology , Streptococcus pyogenes/*genetics , Streptococcus pyogenes/*metabolism , Virulence Factors/*genetics, Animals ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/physiology ; Muscle, Skeletal/microbiology ; Muscle, Skeletal/pathology ; Myositis/genetics ; Myositis/metabolism ; Primates ; RNA, Bacterial/genetics ; RNA, Bacterial/metabolism ; Streptococcus pyogenes/pathogenicity ; Virulence/genetics ; Virulence Factors/metabolism

المؤلفون: Kachroo P; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Eraso JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY, USA., Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Nasser W; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Bernard PE; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Saavedra MO; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Arredondo MJ; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Strope B; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Do H; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Kumaraswami M; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Vuopio J; Institute of Biomedicine, Medical Microbiology and Immunology, University of Turku, Turku, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Gröndahl-Yli-Hannuksela K; Institute of Biomedicine, Medical Microbiology and Immunology, University of Turku, Turku, Finland., Kristinsson KG; Department of Clinical Microbiology, Landspitali University Hospital, Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Gottfredsson M; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Infectious Diseases, Landspitali University Hospital, Reykjavik, Iceland., Pesonen M; Helsinki Institute of Information Technology, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland.; Department of Computer Science, Aalto University, Espoo, Finland., Pensar J; Helsinki Institute of Information Technology, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland., Davenport ER; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA., Clark AG; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA., Corander J; Helsinki Institute of Information Technology, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland.; Department of Biostatistics, University of Oslo, Oslo, Norway., Caugant DA; Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway., Gaini S; Medical Department, Infectious Diseases Division, National Hospital of the Faroe Islands, Tórshavn, Denmark.; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Science and Technology, Centre of Health Research, University of the Faroe Islands, Tórshavn, Denmark., Magnussen MD; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Thetis, Food and Environmental Laboratory, Torshavn, Denmark., Kubiak SL; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Nguyen HAT; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Long SW; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA., Porter AR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., DeLeo FR; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, TX, USA. JMMusser@houstonmethodist.org.; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA. JMMusser@houstonmethodist.org.; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY, USA. JMMusser@houstonmethodist.org.

المصدر: Nature genetics [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 548-559. Date of Electronic Publication: 2019 Feb 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genome, Bacterial/*genetics , Streptococcus pyogenes/*genetics , Transcriptome/*genetics , Virulence/*genetics, Gene Expression Regulation, Bacterial/genetics ; Genome-Wide Association Study/methods ; Genomics/methods ; Phylogeny ; Quantitative Trait Loci/genetics

المؤلفون: Zhu L; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Olsen RJ; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA., Beres SB; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Eraso JM; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Saavedra MO; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Kubiak SL; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Cantu CC; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA., Jenkins L; Department of Comparative Medicine, Houston Methodist Research Institute, Houston, Texas, USA., Charbonneau ARL; Animal Health Trust, Newmarket, Suffolk, United Kingdom.; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom., Waller AS; Animal Health Trust, Newmarket, Suffolk, United Kingdom., Musser JM; Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.; Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2019 Feb 01; Vol. 129 (2), pp. 887-901. Date of Electronic Publication: 2019 Jan 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins*/biosynthesis , Bacterial Proteins*/genetics , Carrier Proteins*/biosynthesis , Carrier Proteins*/genetics , Fasciitis, Necrotizing*/genetics , Fasciitis, Necrotizing*/metabolism , Fasciitis, Necrotizing*/pathology , Gene Expression Regulation, Bacterial* , Myositis*/genetics , Myositis*/metabolism , Myositis*/microbiology , Myositis*/pathology , Streptococcus pyogenes*/genetics , Streptococcus pyogenes*/metabolism , Streptococcus pyogenes*/pathogenicity, Animals ; Cell Line ; Disease Models, Animal ; Humans ; Mice