نتائج البحث - "Caoimhe H. Kiernan"

1

دورية أكاديمية

Overcoming immune checkpoint blockade resistance in solid tumors with intermittent ITK inhibition

المؤلفون: Manzhi Zhao, Ling Li, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Floris Dammeijer, Marjan van Meurs, Inge Brouwers-Haspels, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Rudi W. Hendriks, Joachim G. Aerts, Yvonne M. Mueller, Peter D. Katsikis

المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/894d1a0cf952487080d6943e463aba2e

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2

دورية أكاديمية

Ibrutinib directly reduces CD8+T cell exhaustion independent of BTK

المؤلفون: Ling Li, Manzhi Zhao, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Marjan van Meurs, Inge Brouwers-Haspels, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Rudi W. Hendriks, Yvonne M. Mueller, Peter D. Katsikis

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: immune checkpoint blockade, T-cell exhaustion, ibrutinib, BTK inhibitor, CD8+ T cells, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1201415/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/3847fcbb75c24886b8cbbde00a41f92f

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3

دورية أكاديمية

Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8868b5c6ee1046f79b63a7f738da79df

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4

دورية أكاديمية

Microenvironment-Dependent Gradient of CTL Exhaustion in the AE17sOVA Murine Mesothelioma Tumor Model

المؤلفون: Jennifer L. Hope, Panagiota I. Spantidea, Caoimhe H. Kiernan, Christopher J. Stairiker, Laurine C. Rijsbergen, Marjan van Meurs, Inge Brouwers-Haspels, Yvonne M. Mueller, Delia J. Nelson, Linda M. Bradley, Joachim G. J. V. Aerts, Peter D. Katsikis

المصدر: Frontiers in Immunology, Vol 10 (2020)

مصطلحات موضوعية: cancer, CD8+ T cells, T cell exhaustion, tumors, peripheral lymphoid organs, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.03074/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/244d90e4006c4431ab1b57e407dbf2cf

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MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses

المؤلفون: Jennifer L. Hope, Manzhi Zhao, Christopher J. Stairiker, Caoimhe H. Kiernan, Alison J. Carey, Yvonne M. Mueller, Marjan van Meurs, Inge Brouwers-Haspels, Dennis C. Otero, Eun-Ah Bae, Hannah A. Faso, Alex Maas, Hans de Looper, Paolo M. Fortina, Isidore Rigoutsos, Linda M. Bradley, Stefan J. Erkeland, Peter D. Katsikis

المساهمون: Immunology, Cell biology, Hematology

المصدر: Journal of immunology (Baltimore, Md. : 1950), 208(3), 603-617. American Association of Immunologists

مصطلحات موضوعية: microRNA, Immunology, CD8+ T cells, miR-139, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3f2bca13f38066d8dc8b044c3fbbe6
http://www.scopus.com/inward/record.url?scp=85123567889&partnerID=8YFLogxK

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Allogeneic Chondrogenic Mesenchymal Stromal Cells Alter Helper T Cell Subsets in CD4+ Memory T Cells

المؤلفون: Eric Farrell, Janneke Witte-Bouma, Erik Lubberts, Patrick S. Asmawidjaja, Caoimhe H. Kiernan, Niamh Fahy, Eppo B. Wolvius, Pieter A.J. Brama

المساهمون: Immunology, Rheumatology, Oral and Maxillofacial Surgery, Orthopedics and Sports Medicine

المصدر: Tissue Engineering-Part A, 26(9-10), 490-502. Mary Ann Liebert Inc.

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Regulatory T cell, T-Lymphocytes, Osteoimmunology, medicine.medical_treatment, T cell, 0206 medical engineering, Population, Biomedical Engineering, Bioengineering, 02 engineering and technology, Biology, Mesenchymal Stem Cell Transplantation, Biochemistry, Biomaterials, 03 medical and health sciences, Immune system, medicine, Humans, education, Bone regeneration, Cells, Cultured, 030304 developmental biology, 0303 health sciences, education.field_of_study, Interleukin-6, Mesenchymal stem cell, Cell Differentiation, Mesenchymal Stem Cells, T-Lymphocytes, Helper-Inducer, 020601 biomedical engineering, Coculture Techniques, Cell biology, medicine.anatomical_structure, Cytokine, Leukocytes, Mononuclear, Chondrogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c53fe9726e810999b85f095f8a32d8
https://doi.org/10.1089/ten.tea.2019.0177

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Immunophenotyping and machine learning identify distinct immunotypes that predict COVID-19 clinical severity

مصطلحات موضوعية: Coronavirus disease 2019 (COVID-19), biology, business.industry, Machine learning, computer.software_genre, Tertiary care, Hierarchical clustering, Antibody response, Immunophenotyping, biology.protein, Medicine, Clinical severity, Artificial intelligence, Personalized therapy, Antibody, business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4ee7016575b8d7f20a18e3f8667441e0
https://doi.org/10.1101/2021.05.07.21256531

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UNDERSTANDING TISSUE-ENGINEERED ENDOCHONDRAL OSSIFICATION; TOWARDS IMPROVED BONE FORMATION

المؤلفون: Eric Farrell, Callie Knuth, Eppo B. Wolvius, Roberto Narcisi, Caoimhe H. Kiernan

المساهمون: Oral and Maxillofacial Surgery, Orthopedics and Sports Medicine

المصدر: European Cells & Materials, Vol 37, Pp 277-291 (2019)
European cells & materials, 37, 277-291. AO Research Institute

مصطلحات موضوعية: lcsh:Diseases of the musculoskeletal system, 0206 medical engineering, lcsh:Surgery, regenerative medicine, 02 engineering and technology, Regenerative medicine, Bone and Bones, Extracellular matrix, Tissue engineering, Osteogenesis, Animals, Humans, Medicine, Bone formation, bone tissue engineering, Process (anatomy), Endochondral ossification, Tissue Engineering, business.industry, vascularisation, Mesenchymal stem cell, Mesenchymal Stem Cells, lcsh:RD1-811, 020601 biomedical engineering, mesenchymal stem cell differentiation, Extracellular Matrix, Cell biology, immune system, Bone Substitutes, collagen type X, Mesenchymal stem cell differentiation, lcsh:RC925-935, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5bed87aa36317b3fcd1a75a695b4e0
https://pure.eur.nl/en/publications/943cfca4-e57d-48ae-b9b8-1638a30748ef

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MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8

المؤلفون: Jennifer L, Hope, Manzhi, Zhao, Christopher J, Stairiker, Caoimhe H, Kiernan, Alison J, Carey, Yvonne M, Mueller, Marjan, van Meurs, Inge, Brouwers-Haspels, Dennis C, Otero, Eun-Ah, Bae, Hannah A, Faso, Alex, Maas, Hans, de Looper, Paolo M, Fortina, Isidore, Rigoutsos, Linda M, Bradley, Stefan J, Erkeland, Peter D, Katsikis

المصدر: J Immunol

مصطلحات موضوعية: Mice, Knockout, Down-Regulation, Lymphocyte Activation, Listeria monocytogenes, Article, Mice, Inbred C57BL, Mice, MicroRNAs, Orthomyxoviridae Infections, Influenza A virus, Animals, Female, Signal Transduction, T-Lymphocytes, Cytotoxic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6638aed56934e24822095bea3ae5ecb8
https://pubmed.ncbi.nlm.nih.gov/35022277

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Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation

المؤلفون: Leticia G. Leon, Yvonne M. Mueller, Inge Brouwers-Haspels, Marjan van Meurs, Eric M.J. Bindels, Ruben Boers, Joachim Boers, Peter D. Katsikis, Manzhi Zhao, Remco Hoogenboezem, Christopher J. Stairiker, Wilfred F. J. van IJcken, Stefan J. Erkeland, Jennifer L. Hope, Joost Gribnau, Caoimhe H. Kiernan

المساهمون: Immunology, Developmental Biology, Cell biology, Hematology

المصدر: PLoS Pathogens, Vol 16, Iss 6, p e1008555 (2020)
PLoS Pathogens
PLoS Pathogens (print), 16(6):e1008555. Public Library of Science

مصطلحات موضوعية: Physiology, CD8-Positive T-Lymphocytes, Biochemistry, Immune Receptors, Mice, White Blood Cells, Animal Cells, Immune Physiology, Medicine and Health Sciences, Lymphocytic choriomeningitis virus, Cytotoxic T cell, Hepatocyte Nuclear Factor 1-alpha, Biology (General), Promoter Regions, Genetic, Innate Immune System, 0303 health sciences, DNA methylation, Immune System Proteins, T Cells, Chemistry, 030302 biochemistry & molecular biology, hemic and immune systems, Chromatin, Cell biology, Nucleic acids, Cytokines, Epigenetics, Cellular Types, DNA modification, Chromatin modification, Signal Transduction, Research Article, Chromosome biology, QH301-705.5, Immune Cells, Transgene, Immunology, Mice, Transgenic, Cytotoxic T cells, chemical and pharmacologic phenomena, Lymphocytic Choriomeningitis, Microbiology, complex mixtures, 03 medical and health sciences, In vivo, Virology, DNA-binding proteins, Genetics, Animals, Gene Regulation, Molecular Biology, 030304 developmental biology, Blood Cells, T-cell receptor, Biology and Life Sciences, Proteins, Cell Biology, DNA, Molecular Development, RC581-607, In vitro, Regulatory Proteins, T Cell Receptors, CTL, Immune System, Anergy, Parasitology, Gene expression, Immunologic diseases. Allergy, human activities, CD8, Developmental Biology, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e356e4a5a1750819b0ddb371e3c3b842
https://doaj.org/article/0638732910034e3dbdc1bc9fe44b7d9d

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