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المؤلفون: Mazen Noureddin, Eric Lawitz, Naim Alkhouri, Robert Jenders, Douglas Denham, Bal Raj Bhandari, Christopher Jones, Cara H. Nelson, Tonya Marmon, Swapna Shenvi, Hiba Graham, Daria Crittenden, Erin Quirk, Diana Chung
المصدر: Journal of Hepatology. 77:S731-S732
مصطلحات موضوعية: Hepatology
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المؤلفون: Chia-Hsiang Hsueh, Ethan Grant, Helen Yu, Thomas Tarnowski, Rita Humeniuk, Franziska Matzkies, Cara H. Nelson, Amy Meng, Ellen Kwan, Andrew N. Billin, Joy Y. Feng, Hoa Truong, Juliane M. Jürgensmeier
المصدر: Clinical pharmacology and therapeutics. 111(2)
مصطلحات موضوعية: Adult, Male, Adolescent, Anti-Inflammatory Agents, Pharmacology, Models, Biological, Arthritis, Rheumatoid, Young Adult, Pharmacokinetics, hemic and lymphatic diseases, medicine, Agammaglobulinaemia Tyrosine Kinase, Bruton's tyrosine kinase, Humans, Pharmacology (medical), Computer Simulation, Drug Dosage Calculations, Protein Kinase Inhibitors, PK/PD models, biology, Clinical Trials, Phase I as Topic, business.industry, Imidazoles, Middle Aged, medicine.disease, Pyrimidines, Drug development, Rheumatoid arthritis, Pharmacodynamics, biology.protein, Female, business, Tyrosine kinase, Dose selection
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المؤلفون: Cara H. Nelson, Christopher Jones, Kevin Klucher, Feng Jin, Tonya Marmon, Diana Chung, Erin Quirk, Daria Crittenden
المصدر: Journal of Hepatology. 77:S716
مصطلحات موضوعية: Hepatology
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المؤلفون: Cara H. Nelson, Christopher Jones, Lois Lee, Tonya Marmon, Diana Chung, Kevin Klucher, Yizhao Li, Erin Quirk, Daria Crittenden
المصدر: Journal of Hepatology. 77:S88
مصطلحات موضوعية: Hepatology
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المؤلفون: Mischa Hepner, Anita Mathias, Saili Yi, Cara H. Nelson, David Breckenridge, Kim Etchevers, John Ling, Uptal D. Patel
المصدر: Clinical pharmacokinetics. 59(9)
مصطلحات موضوعية: 0301 basic medicine, Pyridines, 030232 urology & nephrology, Pharmacology, Placebo, MAP Kinase Kinase Kinase 5, 03 medical and health sciences, Food-Drug Interactions, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Medicine, Humans, Pharmacology (medical), Dosing, Adverse effect, Whole blood, Dose-Response Relationship, Drug, business.industry, Imidazoles, Healthy Volunteers, 030104 developmental biology, Tolerability, Pharmacodynamics, Area Under Curve, Benzamides, business, Ex vivo
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المؤلفون: Justin D. Lutz, Nina Isoherranen, Alex Zelter, Cara H. Nelson, Chi Chi Peng, Catherine K. Yeung
المصدر: FEBS Letters. 590:2527-2535
مصطلحات موضوعية: 0301 basic medicine, Receptors, Retinoic Acid, Substrate channeling, Biophysics, Retinoic acid, Tretinoin, Endoplasmic Reticulum, Biochemistry, DNA-binding protein, Article, Substrate Specificity, Protein–protein interaction, 03 medical and health sciences, chemistry.chemical_compound, Structural Biology, Genetics, medicine, Humans, Amino Acid Sequence, Protein Interaction Maps, neoplasms, Molecular Biology, Peptide sequence, biology, organic chemicals, Endoplasmic reticulum, Cytochrome P450, Retinol-Binding Proteins, Cellular, Cell Biology, Retinoic Acid 4-Hydroxylase, biological factors, Kinetics, 030104 developmental biology, Gene Expression Regulation, chemistry, biology.protein, Carrier Proteins, medicine.drug
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المؤلفون: Fu-Chih Cheng, Cara H. Nelson, Christine Garnett, Lu Wang, Srini Ramanathan, Mischa Hepner, Winnie Weng, Joseph Lin, Liang Fang
المصدر: Clinical Pharmacology & Therapeutics. 98:630-638
مصطلحات موضوعية: Male, medicine.medical_specialty, Time Factors, Metabolite, Action Potentials, Pharmacology, Models, Biological, Risk Assessment, QT interval, law.invention, Electrocardiography, chemistry.chemical_compound, Double-Blind Method, Randomized controlled trial, Heart Conduction System, Heart Rate, Risk Factors, law, Internal medicine, medicine, Humans, Computer Simulation, Pharmacology (medical), Drug Approval, Protein Kinase Inhibitors, Clinical pharmacology, Dose-Response Relationship, Drug, medicine.diagnostic_test, United States Food and Drug Administration, business.industry, Arrhythmias, Cardiac, Waiver, United States, Confidence interval, chemistry, Linear Models, Cardiology, Female, business, Risk assessment, Monte Carlo Method
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المؤلفون: Nina Isoherranen, Justin D. Lutz, Cara H. Nelson
المصدر: The FASEB Journal. 27
مصطلحات موضوعية: Chemistry, Retinoic acid, Retinoic acid receptor beta, Retinoic acid receptor gamma, Retinoid X receptor gamma, Biochemistry, Cell biology, Retinoic acid-inducible orphan G protein-coupled receptor, chemistry.chemical_compound, CYP26A1, Retinoic acid receptor, Retinoic acid receptor alpha, Genetics, Molecular Biology, Biotechnology
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المؤلفون: Cara H. Nelson, Brian Buttrick, Nina Isoherranen
المصدر: Current topics in medicinal chemistry. 13(12)
مصطلحات موضوعية: medicine.medical_treatment, Retinoic acid, Endogeny, Biology, Pharmacology, Article, Targeted therapy, Xenobiotics, chemistry.chemical_compound, CYP26A1, Structure-Activity Relationship, Cytochrome P-450 Enzyme System, Psoriasis, Drug Discovery, medicine, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Enzyme Inhibitors, chemistry.chemical_classification, Molecular Structure, Cytochrome P450, General Medicine, Cell cycle, Retinoic Acid 4-Hydroxylase, medicine.disease, Enzyme, chemistry, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d097aab059f1054972d1ffc27d469cc
https://pubmed.ncbi.nlm.nih.gov/23688132 -
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المؤلفون: Gordon L. Amidon, John M. Hilfinger, Charles E. McKenna, Chester J. Provoda, Kyung Dall Lee, Ulrika Tehler, Larryn W. Peterson, Cara H. Nelson
مصطلحات موضوعية: Cytosol alanyl aminopeptidase, Organophosphonates, Peptide, Biology, Aminopeptidase, Aminopeptidases, Antiviral Agents, Article, Substrate Specificity, Puromycin-Sensitive Aminopeptidase, chemistry.chemical_compound, Cytosine, In vivo, Virology, Humans, Prodrugs, Pharmacology, chemistry.chemical_classification, Prodrug, Recombinant Proteins, Kinetics, Enzyme, chemistry, Biochemistry, Puromycin, Caco-2 Cells, Cidofovir
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b687940304da13154434e68db4038be
https://europepmc.org/articles/PMC2830364/