المؤلفون: Ladekarl, Morten

المصدر: Ladekarl, M 2023, ' Pembrolizumab for second line treatment of advanced hepatocellular carcinoma-who would benefit? ', Chinese clinical oncology, vol. 12, no. 2, 10, pp. 10 . https://doi.org/10.21037/cco-23-17

مصطلحات موضوعية: hepatocellular carcinoma (HCC), Oncology, Immune check point inhibitor, Antibodies, Monoclonal, Humanized/pharmacology, Humans, General Medicine, pembrolizumab, second line, Sorafenib, randomized study, Carcinoma, Hepatocellular/drug therapy, Liver Neoplasms/drug therapy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de23b28cc5d0be3910845491adf236ff
https://vbn.aau.dk/ws/files/526457092/Ladekarl_2023_._Pembrolizumab_for_second_line_treatment_of_advanced_hepatocellular_carcinoma_who_would_benefit.pdf

المؤلفون: Jessie Neuckermans, Sien Lequeue, Paul Claes, Anja Heymans, Juliette H. Hughes, Haaike Colemonts-Vroninks, Lionel Marcélis, Georges Casimir, Philippe Goyens, Geert A. Martens, James A. Gallagher, Tamara Vanhaecke, George Bou-Gharios, Joery De Kock

المساهمون: Faculty of Medicine and Pharmacy, Pharmaceutical and Pharmacological Sciences, Experimental in vitro toxicology and dermato-cosmetology, Medicine and Pharmacy academic/administration

المصدر: Genes; Volume 14; Issue 3; Pages: 693

مصطلحات موضوعية: Pharmacology, Toxicology and Pharmaceutics(all), mice, Phenotype, hepatology, Genetics, Animals, Tyrosinemias/drug therapy, liver disease, hereditary tyrosinemia type 1, nitisinone, transcriptomics, alkaptonuria, hepatocellular carcinoma, gene signature, Carcinoma, Hepatocellular/drug therapy, Genetics (clinical), Liver Neoplasms/drug therapy, Tyrosine/genetics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf205983b81b8fede96d9f6db53217dd

المؤلفون: Helder Cardoso, Ana Margarida Alves, Margarida Marques, Ana Maria Vale, Pedro Pereira, Guilherme Macedo

المصدر: GE: Portuguese Journal of Gastroenterology, Vol 23, Iss 5, Pp 243-248 (2016)

مصطلحات موضوعية: Antineoplastic Agents/therapeutic use, Carcinoma, Hepatocellular/drug therapy, Liver Neoplasms/drug therapy, Sorafenib, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2341454516300321; https://doaj.org/toc/2341-4545

URL الوصول: https://doaj.org/article/8af497d685fd4275a89eae4a30ec6740

المؤلفون: Mrzljak, Anna, Cigrovski Berković, Maja, Giovanardi, Francesco, Quirino, Lai

المصدر: Croatian Medical Journal
Volume 63
Issue 2

مصطلحات موضوعية: Carcinoma, Hepatocellular / drug therapy, Carcinoma, Hepatocellular / pathology, Liver Neoplasms / pathology, Diabetes Mellitus, Type 2 / complications, Humans, General Medicine, Liver Neoplasms / drug therapy, Prognosis, hepatocelular carcinoma, diabetes mellitus, NAFLD, outcomes, death, progressive disease, locoregional therapy, recurrence

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32bf6fa6eec85c140c314976385bc5d
https://doi.org/10.3325/cmj.2022.63.176

المؤلفون: Tsinat Berhane, Anja Holm, Kasper Thystrup Karstensen, Andreas Petri, Mirolyuba Simeonova Ilieva, Henrik Krarup, Mogens Vyberg, Marianne Bengtson Løvendorf, Sakari Kauppinen

المصدر: Berhane, T, Holm, A, Karstensen, K T, Petri, A, Ilieva, M S, Krarup, H, Vyberg, M, Løvendorf, M B & Kauppinen, S 2022, ' Knockdown of the long noncoding RNA PURPL induces apoptosis and sensitizes liver cancer cells to doxorubicin ', Scientific Reports, vol. 12, no. 1, 19502 . https://doi.org/10.1038/s41598-022-23802-9
Berhane, T, Holm, A, Karstensen, K T, Petri, A, Ilieva, M S, Krarup, H, Vyberg, M, Løvendorf, M B & Kauppinen, S 2022, ' Knockdown of the long noncoding RNA PURPL induces apoptosis and sensitizes liver cancer cells to doxorubicin ', Scientific Reports, vol. 12, 19502 . https://doi.org/10.1038/s41598-022-23802-9

مصطلحات موضوعية: Multidisciplinary, Carcinoma, Hepatocellular, Liver Neoplasms, Doxorubicin/pharmacology, Apoptosis, Carcinoma, Hepatocellular/drug therapy, Liver Neoplasms/drug therapy, Cell Line, Gene Expression Regulation, Neoplastic, Cell Proliferation/genetics, SDG 3 - Good Health and Well-being, Doxorubicin, Apoptosis/genetics, Cell Line, Tumor, Humans, Tumor Suppressor Protein p53/genetics, RNA, Long Noncoding, Tumor Suppressor Protein p53, RNA, Long Noncoding/metabolism, Cell Proliferation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec59f073855c358533957039449abe8
https://pubmed.ncbi.nlm.nih.gov/36376362

المؤلفون: Isabelle Colle, Hendrik Reynaert

المساهمون: Basic (bio-) Medical Sciences, Gastroenterology, Laboratory of Molecullar and Cellular Therapy, Liver Cell Biology

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4811 (2019)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cirrhosis, Antineoplastic Agents, Hormonal/therapeutic use, Octreotide, Review, Carcinoma, Hepatocellular/drug therapy, lcsh:Chemistry, 0302 clinical medicine, lcsh:QH301-705.5, Spectroscopy, Medicine(all), Clinical Trials as Topic, somatostatin analogues, Somatostatin receptor, High mortality, Liver Neoplasms, General Medicine, hepatocellular carcinoma, Computer Science Applications, somatostatin receptor, Somatostatin, Treatment Outcome, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Primary liver cancer, medicine.drug, medicine.medical_specialty, Carcinoma, Hepatocellular, Antineoplastic Agents, Hormonal, somatostatin, Catalysis, Liver Neoplasms/drug therapy, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Somatostatin/analogs & derivatives, Physical and Theoretical Chemistry, Molecular Biology, business.industry, Organic Chemistry, Cancer, medicine.disease, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, business, octreotide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8cab1d2534357b797fe0b2be8b200b
http://europepmc.org/articles/PMC6801667

المؤلفون: Ana Margarida Alves, Guilherme Macedo, Ana Maria Horta e Vale, Pedro Pereira, Hélder Cardoso, Margarida Marques

المصدر: GE-Portuguese Journal of Gastroenterology v.23 n.5 2016
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
CIÊNCIAVITAE
GE: Portuguese Journal of Gastroenterology, Vol 23, Iss 5, Pp 243-248 (2016)
GE-Portuguese Journal of Gastroenterology, Volume: 23, Issue: 5, Pages: 243-248, Published: OCT 2016
GE Portuguese Journal of Gastroenterology

مصطلحات موضوعية: Oncology, Sorafenib, Alcoholic liver disease, medicine.medical_specialty, medicine.medical_treatment, Neoplasia do Fígado/quimioterapia, Antineoplásicos/quimioterapia, Gastroenterology, Carcinoma, Hepatocellular/drug therapy, Liver Neoplasms/drug therapy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, lcsh:RC799-869, Adverse effect, Chemotherapy, business.industry, Antineoplastic Agents/therapeutic use, Retrospective cohort study, medicine.disease, digestive system diseases, BCLC Stage, Discontinuation, Carcinoma Hepatocelular/quimioterapia, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Original Article, lcsh:Diseases of the digestive system. Gastroenterology, 030211 gastroenterology & hepatology, business, medicine.drug

وصف الملف: text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b322cce424f90da937065c6380d831
https://doi.org/10.1016/j.jpge.2016.04.006

المؤلفون: Virginia Sanchez-Quiles, Giuseppina Di Giacomo, Salvatore Rizza, Andrea Rasola, Emiliano Maiani, Giuseppe Filomeni, Daniela De Zio, Simone Cardaci, Jonathan S. Stamler, Blagoy Blagoev, Costanza Montagna, Francesco Cecconi

المصدر: Europe PubMed Central
Rizza, S, Montagna, C, Cardaci, S, Maiani, E, Di Giacomo, G, Sanchez-Quiles, V, Blagoev, B, Rasola, A, De Zio, D, Stamler, J S, Cecconi, F & Filomeni, G 2016, ' S-nitrosylation of the mitochondrial chaperone TRAP1 sensitizes hepatocellular carcinoma cells to inhibitors of succinate dehydrogenase ', Cancer Research, vol. 76, no. 14, pp. 4170-4182 . https://doi.org/10.1158/0008-5472.CAN-15-2637

مصطلحات موضوعية: 0301 basic medicine, Succinate Dehydrogenase/antagonists & inhibitors, Cancer Research, Carcinoma, Hepatocellular, Oncology, Necroptosis, Inflammation, Reductase, Carcinoma, Hepatocellular/drug therapy, Liver Neoplasms/drug therapy, Nitric oxide, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Mitochondria/metabolism, medicine, Animals, Humans, HSP90 Heat-Shock Proteins, Settore BIO/10, biology, Cell growth, Succinate dehydrogenase, Liver Neoplasms, Hep G2 Cells, S-Nitrosylation, Aldehyde Oxidoreductases, Molecular biology, Mitochondria, Succinate Dehydrogenase, Mice, Inbred C57BL, Oxidative Stress, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Chaperone (protein), Cancer research, biology.protein, HSP90 Heat-Shock Proteins/metabolism, medicine.symptom, Aldehyde Oxidoreductases/physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5083c5fc91a9ac97df13289f07077e8
https://doi.org/10.1158/0008-5472.can-15-2637

المؤلفون: Marc Pracht, Kenta Motomura, Philippe Merle, Richard S. Finn, Jean-Baptiste Hiriart, Takuji Okusaka, Christophe Borg, Paolo Abada, Masatoshi Kudo, Dong Bok Shin, Guido Gerken, Eric Assenat, Chia Jui Yen, Izumi Ohno, Yoon-Koo Kang, Kun-Ming Rau, Bruno Daniele, Yanzhi Hsu, Andrew X. Zhu, Josep M. Llovet, Peter R. Galle, Manabu Morimoto, Giovanni Brandi, Ho Yeong Lim

المساهمون: Zhu, Andrew X, Kang, Yoon-Koo, Yen, Chia-Jui, Finn, Richard S, Galle, Peter R, Llovet, Josep M, Assenat, Eric, Brandi, Giovanni, Pracht, Marc, Lim, Ho Yeong, Rau, Kun-Ming, Motomura, Kenta, Ohno, Izumi, Merle, Philippe, Daniele, Bruno, Shin, Dong Bok, Gerken, Guido, Borg, Christophe, Hiriart, Jean-Baptiste, Okusaka, Takuji, Morimoto, Manabu, Hsu, Yanzhi, Abada, Paolo B, Kudo, Masatoshi, Harvard Medical School [Boston] (HMS), Asan Medical Center [Seoul], University of Ulsan, National Cheng Kung University (NCKU), David Geffen School of Medicine [Los Angeles], University of California [Los Angeles] (UCLA), University of California-University of California, University Medical Center [Mainz], Icahn School of Medicine at Mount Sinai [New York] (MSSM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Centre Eugène Marquis (CRLCC), Sungkyunkwan University [Suwon] (SKKU), Chang Gung Memorial Hospital [Taipei] (CGMH), Fukuoka University, University of Tokyo [Kashiwa Campus], Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL), G Rummo Hospital, Ospedale del Mare, Gachon University Gil Medical Center [Incheon, Republic of Korea], Universität Duisburg-Essen [Essen], Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) (RIGHT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS [Bourgogne-Franche-Comté]), Hôpital Haut-Lévêque [CHU Bordeaux], CHU Bordeaux [Bordeaux], Tokyo Medical University, Yokohama University School of Medecine, Eli Lilly and Company [Indianapolis], Kindai University

المصدر: The Lancet Oncology
The Lancet Oncology, 2019, 20 (2), pp.282-296. ⟨10.1016/S1470-2045(18)30937-9⟩

مصطلحات موضوعية: Sorafenib, Male, medicine.medical_specialty, Carcinoma, Hepatocellular, Medizin, Antineoplastic Agents, [SDV.CAN]Life Sciences [q-bio]/Cancer, Placebo, Antibodies, Monoclonal, Humanized, Gastroenterology, Ramucirumab, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Internal medicine, medicine, Clinical endpoint, Carcinoma, Humans, Aged, Neoplasm Staging, Intention-to-treat analysis, business.industry, Hazard ratio, Liver Neoplasms, MESH: Alpha-Fetoproteins / analysis, Middle Aged, medicine.disease, digestive system diseases, 3. Good health, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, 030211 gastroenterology & hepatology, Drug Therapy, Combination, Female, alpha-Fetoproteins, MESH: Carcinoma, Hepatocellular / drug therapy, Liver Neoplasms / blood, Liver Neoplasms / drug therapy, Sorafenib / administration & dosage, business, medicine.drug, MESH: Antibodies, Monoclonal, Humanized /administration & dosage, Antineoplastic Agents / administration & dosage, Carcinoma, Hepatocellular / blood

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c659e7762c4ea8ec28743092b9b3bf4c
https://www.ncbi.nlm.nih.gov/pubmed/30665869

المؤلفون: Alexandra Montagner, Nguan Soon Tan, Walter Wahli, Jiapeng Chen

المساهمون: Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), School of Biological Sciences, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), KK Women’s and Children’s Hospital (KKH), Institute of Molecular and Cell Biology, University of Tartu, Center for Integrative Genomics - Institute of Bioinformatics, Génopode (CIG), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne (UNIL)-Université de Lausanne (UNIL), ProdInra, Migration, Nanyang Technological University [Singapour], Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Université de Lausanne = University of Lausanne (UNIL)-Université de Lausanne = University of Lausanne (UNIL), Lee Kong Chian School of Medicine (LKCMedicine)

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2018, 19 (7), pp.1893. ⟨10.3390/ijms19071893⟩
International Journal of Molecular Sciences 7 (19), 1893. (2018)
International Journal of Molecular Sciences, 2018, 19 (7), pp.1893. ⟨10.3390/ijms19071893⟩
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1893 (2018)
International journal of molecular sciences, vol. 19, no. 7, pp. 1893

مصطلحات موضوعية: 0301 basic medicine, PPARβ/δ, NAFLD, NASH, steatosis, liver, lipid metabolism, Cirrhosis, [SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Peroxisome proliferator-activated receptor, Review, lcsh:Chemistry, Non-alcoholic Fatty Liver Disease, PPAR delta, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, Liver Neoplasms, Fatty liver, General Medicine, 3. Good health, Computer Science Applications, Hepatocellular carcinoma, Alimentation et Nutrition, medicine.medical_specialty, Carcinoma, Hepatocellular, Adipokine, digestive system, Catalysis, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Animals, Humans, Food and Nutrition, Physical and Theoretical Chemistry, PPAR-beta, Molecular Biology, Physiologie, business.industry, Organic Chemistry, nutritional and metabolic diseases, Lipid metabolism, medicine.disease, digestive system diseases, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, 030104 developmental biology, Endocrinology, chemistry, lcsh:Biology (General), lcsh:QD1-999, Carcinoma, Hepatocellular/drug therapy, Carcinoma, Hepatocellular/metabolism, Liver Neoplasms/drug therapy, Liver Neoplasms/metabolism, Non-alcoholic Fatty Liver Disease/drug therapy, Non-alcoholic Fatty Liver Disease/metabolism, PPAR delta/metabolism, PPAR delta/therapeutic use, PPAR-beta/metabolism, PPAR-beta/therapeutic use, physiology, Steatosis, Steatohepatitis, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0960421b5cf4f81de9069e21a37d513d
https://hal.inrae.fr/hal-02624144